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This document provides an overview of the topics covered in 10 lectures on biological anthropology and genetics. The lectures cover the following topics: the history of evolutionary theory and anthropology as a field; Mendel's laws of inheritance; cell structure and function; chromosome structure; mitosis and meiosis; DNA, RNA, and protein synthesis; chromosomal abnormalities; and non-Mendelian patterns of inheritance. Key concepts discussed include dominant and recessive traits, karyotypes, the stages of mitosis and meiosis, DNA replication and transcription/translation.
This document provides an overview of the topics covered in 10 lectures on biological anthropology and genetics. The lectures cover the following topics: the history of evolutionary theory and anthropology as a field; Mendel's laws of inheritance; cell structure and function; chromosome structure; mitosis and meiosis; DNA, RNA, and protein synthesis; chromosomal abnormalities; and non-Mendelian patterns of inheritance. Key concepts discussed include dominant and recessive traits, karyotypes, the stages of mitosis and meiosis, DNA replication and transcription/translation.
This document provides an overview of the topics covered in 10 lectures on biological anthropology and genetics. The lectures cover the following topics: the history of evolutionary theory and anthropology as a field; Mendel's laws of inheritance; cell structure and function; chromosome structure; mitosis and meiosis; DNA, RNA, and protein synthesis; chromosomal abnormalities; and non-Mendelian patterns of inheritance. Key concepts discussed include dominant and recessive traits, karyotypes, the stages of mitosis and meiosis, DNA replication and transcription/translation.
Ashok Introduction to Biological Anthropology - ANTH 105
Review Sheet Test 1
Lecture 1: Overview and Introduction to Anthropology Lecture 2: Development of Evolutionary Theory Lecture 3: Mendels laws of Inheritance Lecture 4: The cell: structure and function Lecture 5: Chromosome structure Lecture 6: Mitosis Lecture 7: Meiosis and development Lecture 8: Chromosomal abnormalities Lecture 9: DNA, RNA, protein synthesis Lecture 10: Non Mendelian genetics Lecture 1: Overview and Introduction to Anthropology 1. What Is Anthropology? 2. The subfields of Anthropology 3. How can we study Humans 4. Issues for Physical Anthropologists 5. Scientific Methodology Lecture 2: Development of Evolutionary Theory 1. Aristotle 2. Can you see evolution happening right now? 3. The Scopes Trial - 1925 4. Pre-Darwinian Theories 5. Darwins theory of Evolution Lecture 3: Mendels laws of Inheritance 1. Study of Pea plants 2. Seven characters 3. Dominant Trait / Recessive Trait 4. Homozygous / Heterozygous 5. Character and Trait 6. Gene and Allele 7. Locus 8. Genotype / Phenotype 9. Somatic cell / Germ cell 10. Haploid / Diploid 11. Laws of Mendel: Law of segregation; Law of Independent assortment 12. Monohybrid phenotypic ratios (3:1) 13. Monohybrid genotypic ratios (1:2:1) 14. Applications of Mendel's laws to Humans 15. Know some examples of Human Dominant & Recessive traits 16. Heritability Lecture 4: The cell: structure and function 1. Parts of a cell: Cell membrane, cytoplasm and organelles 2. Organelles: Nucleus 3. Mitochondria 4. Ribosomes 5. Cytoskeleton Lecture 5: Chromosome structure 1. DNA, Chromatin and Chromosome 2. Autosomes 22 pairs 3. Sex Chromosomes 4. Males have 22+XY chromosomes 5. Females have 22+ XX chromosomes 6. Total chromosome # in a somatic cell 7. Total chromosome # in a germ cell 8. What is a karyotype? 9. Telomere 10. Centromere 11. Chromosomes: . P arm and Q arm . Acrocentric / metacentric / submetacentric
Lecture 6: Mitosis 1. Cell division in all parts of the body 2. Division makes identical daughter cells 3. Stages of Mitosis: Prophase, Metaphase, Anaphase, Telophase (nuclear division) 4. Cytokinesis: division of the cytoplasm 5. Apoptosis (programmed cell death) Lecture 7: Meiosis and Development 1. Meiosis- cell division occurs in ovary and testis to produces sperms and ovum 2. Homologous chromosomes / Non homologous chromosomes 3. Sister chromatids 4. Spermatogenesis (sperm production) / Oogenesis (egg formation 5. Meiosis I: prophase, metaphase, anaphase and Telophase two cells 6. Meiosis II: prophase, metaphase, anaphase and Telophase four cells 7. Fertilization 8. Zygote formation 9. Development 10. Twining: Monozygotic and Dizygotic twins
Lecture 8: Chromosomal abnormalities 1. In Autosomes: Numerical & Structural 2. In sex chromosomes: Numerical & Structural 3. Polyploidy 4. Down syndrome ( Trisomy 21) 5. Patau syndrome (Trisomy 13) 6. Edward syndrome ( Trisomy 18) 7. Turner syndrome ( 45, XO) 8. Kinefelters syndrome (47,XXY) 9. XXX and XYY syndrome 10. Deletion / Duplications / Translocation / Inversion
Lecture 9: DNA, RNA, protein synthesis 1. DNA Deoxyribonucleic acid: structure and function 2. RNA Ribonucleic acid: structure and function 3. DNA replication ( ATTCAGTACCGGA TAAGTCATGGCCT) 4. Protein synthesis: Transcription and Translation 5. Transcription is ( DNA to RNA) ATTGCCATTGCACGA-DNA UAACGGUAACGUGCU-mRNA 6. Translation is ( RNA to Protein) UAA CGG UAA CGU GCU-mRNA ( three letter codes) AA -AA - AA -AA -AA (AA different amino acids) 7. Proteins are made up of Amino acids, two amino acids are joined by a peptide bonds 8. Three kinds of RNA: mRNA, tRNA, rRNA