Vildagliptin(vildagliptin)isamedicinewhichis

usedindiabetesmellitus.
Yourmedicine
Diabetesaffectsthecontrolofbloodsugarlevels.In
diabetes,thebodymaynotbeabletoproduce
enoughinsulinortheinsulinthatitproducesmay
nothavethefulleffect.Insomeinstances,thebody
maynotbeabletoproduceanyinsulinatall.Insulin
helpsthebodytousethesugarintheblood
properlyandithelpstopreventbloodsugarlevels
frombecomingtoohigh.Glucagonisanother
hormonewhichisimportantincontrollingblood
sugarlevels.Glucagoncausesbloodsugarlevelsto
risewhentheyarelow.
Vildagliptinincreasestheamountofinsulin
producedbythebody.Italsodecreasestheamount
ofglucagonwhichisproducedbythebody.
Becauseoftheseeffects,Vildagliptincanhelpto
controlbloodsugarlevelsinpeoplewithdiabetes.
Vildagliptinisusedincombinationwithother
medicineswhichhelptocontrolbloodsugarlevels.
Itisveryimportantthatyourbloodsugarleveliswell
controlled.Bloodsugarlevelswhicharetoohighor
toolowcanbedangerous.Yourprescriberora
memberofyourdiabetesteamwillbeabletogive
youinformationonhowtorecognisethewarning
signsofhighandlowbloodsugarlevels.Theywill
alsobeabletotellyouwhattodoifeitherofthese
occurs.
Warningsignscanvaryfrompersontoperson.Ifthe
usualwarningsignsofpoorlycontrolledbloodsugar
levelschangeordisappear,youshouldcontactyour
prescriberoramemberofyourdiabetesteam.
TheamountofVildagliptinyouneedtocontrolyour
bloodsugarlevelswillbeworkedoutbyyour
prescriberoryourdiabetesteam.Theymayalso
adviseyoutomeasureyourbloodsugarregularly
theywillshowyouhowtodothis.Ifyouarehaving
problemscontrollingormeasuringyourbloodsugar,
youshouldcontactyourprescriberoramemberof
yourdiabetesteam.
OtherinformationaboutVildagliptin:
ifyoumissadoseofVildagliptin,takeyour
nextdoseassoonasyouremember.Donot
takeadoubledoseonthesameday.
Donotshareyourmedicinewithotherpeople.It
maynotbesuitableforthemandmayharmthem.
Thepharmacylabelonyourmedicinetellsyouhow
muchmedicineyoushouldtake.Italsotellsyou
howoftenyoushouldtakeyourmedicine.Thisis
thedosethatyouandyourprescriberhaveagreed
youshouldtake.Youshouldnotchangethedoseof
yourmedicineunlessyouaretoldtodosobyyour
prescriber.
Ifyoufeelthatthemedicineismakingyouunwellor
youdonotthinkitisworking,thentalktoyour
prescriber.
Whentotakeyourmedicine
Somemedicinesworkbestiftheyaretakenata
specifictimeofday.Gettingthemostbenefitfrom
yourmedicinecanalsobeaffectedbywhatyoueat,
whenyoueatandthetimesatwhichyoutakeother
medicines.
SpecificinformationonwhentotakeVildagliptincan
befoundinthePatientInformationLeafletthat
comeswiththismedicineoronthemedicinelabel.
Youcanalsoaskyourdoctororpharmacistfor
informationaboutwhentotakeyourmedicine.
Howtotakeyourmedicine
Somemedicineshavespecificinstructionsabout
howtotakethem.Thisisbecausetheyworkbetter
whentakencorrectly.Theseinstructionscaninclude
gettingtherightdoseandspecialinstructionsfor
preparingthemedicine.
SpecificinformationonhowtotakeVildagliptincan
befoundinthePatientInformationLeafletthat
comeswiththismedicineoronthemedicinelabel.
Alternatively,youcanrequestinformationabouthow
totakeyourmedicinefromyourdoctoror
pharmacist.
Ifyouarehavingproblemstakingthisformof
Vildagliptin,youshouldtalktoyourprescriberor
pharmacist.Theymaybeabletogiveyouadviceon
otherwaystotakeyourmedicineorother
preparationsthatareeasierforyoutotake.
Takingtoomuchofyourmedicine
Takingextradosesofsomemedicinescanbe
harmful.Insomecasesevenoneextradosecan
causeyouproblems.Ifyoutakeextradosesofyour
medicine,youmustgetmedicaladviceimmediately.
Youmayneedatesttoassesstheeffectoftaking
extradoses.Thisisbecausetheeffectsoftaking
toomuchmedicineareverycomplexsoitisvery
importantthatyouseekmedicaladvice.
Contactyourprescriber,pharmacist,specialistclinic
orcall111foradvice.
Makesureyoutakeallofyourmedicinecontainers
withyouifyouareadvisedtogotohospital.
Stoppingyourmedicine
Suddenlystoppingyourmedicinemaycausevery
highbloodsugarlevels.Thiscanbevery
dangerous.Thisiswhyyoumustspeaktoyour
prescriberoramemberofyourdiabetesteamifyou
arehavinganyproblemstakingyourmedicine.
Ifyouarenothavinganyproblemstakingthis
medicine,donotstoptakingitunlessadvisedtodo
sobyyourprescriberoramemberofyourdiabetes
team.
Ifyouareinanydoubt,contactyourprescriber,
pharmacist,specialistclinicorcall111.
Lookingafteryourmedicine
Theinstructionsonhowyoushouldkeepyour
medicineareonthepharmacylabel.Itisagood
ideatokeepyourmedicineintheoriginalcontainer.
Thiswillhelptokeepyourmedicineinthebest
conditionandalsoallowyoutocheckthe
instructions.Donottakethemedicineifthe
packagingappearstohavebeentamperedwithorif
themedicineshowsanysignsofdamage.Make
surethatthemedicineisoutofthesightandreach
ofchildren.
SpecificinformationonhowtolookafterVildagliptin
canbefoundinthePatientInformationLeafletthat
comeswiththismedicineoronthemedicinelabel.
Alternatively,youcanrequestinformationabouthow
tolookafteryourmedicinefromyourdoctoror
pharmacist.
Youmustnottakethemedicineaftertheexpirydate
shownonthepackaging.Ifyouhaveanyunused
medicine,returnittoyourpharmacistwhowill
disposeofitsafely.
Whetherthismedicineissuitableforyou
Vildagliptinisnotsuitableforeveryoneandsome
peopleshouldneveruseit.Otherpeopleshould
onlyuseitwithspecialcare.Itisimportantthatthe
personprescribingthismedicineknowsyourfull
medicalhistory.
Yourprescribermayonlyprescribethismedicine
withspecialcareormaynotprescribeitatallifyou:
areallergicorsensitivetoorhavehada
reactiontoanyoftheingredientsinthe
medicine
haveliverproblems
havecertaintypesofheartproblems
havediabetesthatrequirestreatmentwith
insulin
havekidneyproblems
areonhaemodialysis
haveskinproblemssuchasulcers
Furthermoretheprescribermayonlyprescribethis
medicinewithspecialcareormaynotprescribeitat
allforsomeoneundertheageof18years.
Aspartoftheprocessofassessingsuitabilityto
takethismedicineaprescribermayalsoarrange
tests:
todeterminewhetherornotthemedicineis
suitableandwhetheritmustbeprescribed
withextracare
tocheckthatthismedicineisnothavingany
undesiredeffects
OvertimeitispossiblethatVildagliptincanbecome
unsuitableforsomepeople,ortheymaybecome
unsuitableforit.Ifatanytimeitappearsthat
Vildagliptinhasbecomeunsuitable,itisimportant
thattheprescriberiscontactedimmediately.
Sideeffects
Amedicineisonlymadeavailabletothepublicifthe
clinicaltrialshaveshownthatthebenefitsoftaking
themedicineoutweightherisks.
Onceamedicinehasbeenlicensed,informationon
themedicine'seffects,bothintendedand
unintended,iscontinuouslyrecordedandupdated.
Somesideeffectsmaybeseriouswhileothersmay
onlybeamildinconvenience.Veryoccasionally,
certainsideeffectscanbebeneficial.
Everyone'sreactiontoamedicineisdifferent.Itis
difficulttopredictwhichsideeffectsyouwillhave
fromtakingaparticularmedicine,orwhetheryou
willhaveanysideeffectsatall.Theimportantthing
istotellyourprescriberorpharmacistifyouare
havingproblemswithyourmedicine.
Aspartoftreatment,thismedicinemaybeusedin
combinationwithothermedicines.Theinformation
includedhererelatestothesideeffectscausedby
thecombinationofthismedicinewithother
medicinesthatitisusuallygivenwith.Theremaybe
moreinformationonthesideeffectsofVildagliptinin
thePatientInformationLeafletforVildagliptin.
Common:Morethan1in100peoplewhotake
Vildagliptin
chills
decreasedbloodsugarlevelsverylow
bloodsugarlevelsmayleadtolossof
consciousness,impairmentofbrainfunction,
convulsionsordeath.Ifyourbloodsugar
levelsareloworyouarehavingwarning
signsoflowbloodsugarlevelsyouwillneed
tohavesomesugar.Suitablefoodsinclude
dextrosetablets,sweets,biscuits,sugaryfruit
juiceorsugar.Yourprescribermayhavealso
prescribedyouglucagon.Glucagonisan
emergencytreatmentforpeoplewithverylow
bloodsugarlevels.Ifyouhavebeen
prescribedglucagon,makesureyouoryour
Vildagliptin
Vildagliptin50mgtablets
Whenusedindiabetesmellitus
Providedbywww.medicines.org.uk/guides Page1of2 Lastupdated03Sep13
Copyright2010Datapharm
carerknowswhentouseit,whereitisstored
andhowtouseit
feelingdizzy
gastrooesophagealreflux
headaches
increasedsweating
nauseathishasonlybeenreportedwhen
Vildagliptinhasbeentakenincombination
withmetformin
oedemaoftheextremities
tremors
weakness
weightgainthishasonlybeenreported
whenVildagliptinhasbeentakenin
combinationwithaglitazone
Uncommon:Morethan1in1000peoplewhotake
Vildagliptin
abnormallaboratorytestresults
constipation
diarrhoea
flatulence
jointpain
tirednessthishasonlybeenreportedwhen
Vildagliptinhasbeentakenincombination
withmetformin
Veryrare:Fewerthan1in10,000peoplewhotake
Vildagliptin
inflammationofthenoseandthroat
respiratorytractinfection
Thefrequencyofthesesideeffectsisunknown
angioedema
liverproblemsstoptakingVildagliptinand
seekmedicaladviceifyoudevelopjaundice
pancreatitisseekmedicaladviceifyou
developpersistentorseverestomachpain
skinlesions
urticaria
Ifyoufeelunwellorifyouhaveconcernsabouta
sideeffect,youwillneedtoseekadvice.Ifyoufeel
veryill,getmedicalhelpstraightaway.Contactyour
prescriber,pharmacist,nurseorcall111.
Takingothermedicines
Ifyouaretakingmorethanonemedicinetheymay
interactwitheachother.Attimesyourprescriber
maydecidetousemedicinesthatinteract,inother
casesthismaynotbeappropriate.
Thedecisiontousemedicinesthatinteractdepends
onyourspecificcircumstances.Yourprescribermay
decidetousemedicinesthatinteract,ifitisbelieved
thatthebenefitsoftakingthemedicinestogether
outweightherisks.Insuchcases,itmaybe
necessarytoalteryourdoseormonitoryoumore
closely.
Tellyourprescriberthenamesofallthemedicines
thatyouaretakingsothattheycanconsiderall
possibleinteractions.Thisincludesallthemedicines
whichhavebeenprescribedbyyourGP,hospital
doctor,dentist,nurse,healthvisitor,midwifeor
pharmacist.Youmustalsotellyourprescriberabout
medicineswhichyouhaveboughtoverthecounter
withoutprescriptions.
Thefollowingtypesofmedicinemayinteractwith
Vildagliptin:
thiazidediuretics
corticosteroids
thyroidhormones
sympathomimetics
ACEinhibitors
sulphonylureas
IfyouaretakingVildagliptinandoneoftheabove
typesofmedicines,makesureyourprescriber
knowsaboutit.
Complementarypreparationsandvitamins
Medicinescaninteractwithcomplementary
preparationsandvitamins.Ingeneral,thereisnot
muchinformationavailableaboutinteractions
betweenmedicinesandcomplementary
preparationsorvitamins.
Ifyouareplanningtotakeorarealreadytakingany
complementarypreparationsandvitaminsyou
shouldaskyourprescriberwhetherthereareany
knowninteractionswithVildagliptin.
Yourprescribercanadvisewhetheritisappropriate
foryoutotakecombinationsthatareknownto
interact.Theycanalsodiscusswithyouthe
possibleeffectthatthecomplementarypreparations
andvitaminsmayhaveonyourcondition.
Ifyouexperienceanyunusualeffectswhiletaking
thismedicineincombinationwithcomplementary
preparationsandvitamins,youshouldtellyour
prescriber.
Drivingandoperatingmachinery
Whentakinganymedicineyoushouldbeawarethat
itmightinterferewithyourabilitytodriveoroperate
machinerysafely.
InthecaseofVildagliptin:
thismedicinecouldaffectyourabilitytodrive
oroperatemachinery
Youshouldseehowthismedicineaffectsyou
beforeyoujudgewhetheryouaresafetodriveor
operatemachinery.Ifyouareinanydoubtabout
whetheryoushoulddriveoroperatemachinery,talk
toyourprescriber.
Diet
Medicinescaninteractwithcertainfoods.Insome
cases,thismaybeharmfulandyourprescribermay
adviseyoutoavoidcertainfoods.
InthecaseofVildagliptin:
Vildagliptinisnotknowntointeractwithfood.
Youshouldcontinueonthedietadvisedby
yourdieticianorprescriber
Formoreadvicespeaktoyourprescriber,
nutritionistorpharmacist.
Alcohol
Alcoholcaninteractwithcertainmedicines.
InthecaseofVildagliptin:
therearenoknowninteractionsbetween
alcoholandVildagliptin
Familyplanningandpregnancy
Mostmedicines,insomeway,canaffectthe
developmentofababyinthewomb.Theeffecton
thebabydiffersbetweenmedicinesandalso
dependsonthestageofpregnancythatyouhave
reachedwhenyoutakethemedicine.
InthecaseofVildagliptin:
donottakethismedicineduringpregnancy
ifyoubecomepregnant,orthinkyouhave
becomepregnantwhiletakingVildagliptin,
youmustcontactyourprescriber
Peoplewithdiabetesmaystarttohaveinsulin
insteadofVildagliptintocontroltheirbloodsugar
duringpregnancy.IfyouaretakingVildagliptinand
areplanningtobecomepregnant,becomepregnant
orthinkthatyouarepregnant,talktoamemberof
yourdiabetesteam.Formoreinformationon
managingyourdietandyourdiabetesduringyour
pregnancy,talktoyourprescriberoramemberof
yourdiabetesorantenatalteam.
Breastfeeding
Certainmedicinescanpassintobreastmilkand
mayreachyourbabythroughbreastfeeding.
InthecaseofVildagliptin:
womenwhoarebreastfeedingmustnottake
thismedicine
Beforeyouhaveyourbabyyoushoulddiscuss
breastfeedingwithyourdoctorormidwife.Ifyou
wishtobreastfeedyoushoulddiscusswithyour
prescriberwhetherthereareanyothermedicines
youcouldtakewhichwouldalsoallowyouto
breastfeed.Youshouldnotstopthismedicine
withouttakingadvicefromyourdoctor.
Ingredientsofyourmedicine
Medicinescontainactiveingredients.Theymayalso
containother,additionalingredientsthathelpensure
thestability,safetyandeffectivenessofthe
medicine.Theyarealsoaddedtoimprovethe
medicine'stasteandappearanceandtomakeit
easiertotake.Somemaybeusedtoprolongthelife
ofthemedicine.
Thismedicinecontainsvildagliptin.
Weareunabletolistalloftheingredientsforyour
medicinehere.Forafulllist,youshouldrefertothe
patientinformationleafletthatcomeswiththis
medicine.Youshouldcheckthatyouareableto
taketheingredientsofyourmedicine,especiallyif
youhaveanyallergies.Youshouldalsocheck
whetheranyoftheseingredientsareknowntohave
sideeffects.
Ifyouarenotabletotakeanyoftheingredientsin
yourmedicine,talktoyourprescriberorpharmacist
toseeiftheycansuggestanalternativemedicine.If
youhavereactedbadlytoVildagliptinbefore,donot
takeVildagliptin.Talktoyourprescriber,pharmacist
ornurseassoonaspossible.
Vildagliptin
Vildagliptin50mgtablets
Whenusedindiabetesmellitus
Providedbywww.medicines.org.uk/guides Page2of2 Lastupdated03Sep13
Copyright2010Datapharm