Kitia Mae C.

Pepito BSN4Y1-8B



DRUG


Classification

Action

Indication

Contraindication

Adverse effects

Nursing
Responsibilities


Generic
name:

clonidine
hydrochlori
de, USP




Brand
name:

Catapres


Anti
hypertensive
Sympatholyti
c (centrally
acting)
Central
analgesic


Reduced
sympathetic
outflow from
the central
nervous
system and in
decreases in
peripheral
resistance,
renal vascular
resistance, hea
rt rate,
and blood
pressure.

Hypertension, used
alone or as part of
combination
therapy
Treatment of
severe pain in
cancer patients in
combination with
opiates; epidural
more effective
with neuropathic p
ain (Duraclon)
Unlabeled
uses: Tourette's syn
drome; migraine,
decreases severity
and frequency;
menopausal
flushing, decreases
severity and
frequency of
episodes;

Contraindicated
with
hypersensitivity
to clonidine or
any adhesive layer
components of
the transdermal
system.
Use cautiously
with severe
coronary
insufficiency,
recent
MI, cerebrovascu
lar disease;
chronic renal
failure; pregnancy,
lactation.


CNS: Drowsiness,
sedation,
dizziness, headache,
fatigue that tend to
diminish within 46 wk,
dreams, nightmares,
insomnia,
hallucinations, delirium,
nervousness,
restlessness, anxiety,
depression, retinal
degeneration
CV: CHF, orthostatic
hypotension,
palpitations,
tachycardia, bradycardi
a, Raynaud's phenomen
on, ECG abnormalities
manifested
as Wenckebach period
or ventricular trigeminy
Dermatologic: Rash,
angioneurotic edema,
hives, urticaria, hair
thinning and alopecia


Take this drug
exactly as prescribed. Do
not miss doses. Do not
discontinue the drug
unless so instructed. Do
not discontinue
abruptly; life-
threatening adverse
effects may occur. If you
travel, take an adequate
supply of drug.
Use the
transdermal system as
prescribed; refer to
directions in package
insert, or contact your
health care provider
with questions. Be sure
to remove old systems
before applying new
ones.
Attempt lifestyle
changes that will reduce
your blood pressure:
Stop smoking and using
alcohol; lose weight

Kitia Mae C. Pepito BSN4Y1-8B



DRUG


Classification

Action

Indication

Contraindication

Adverse effects

Nursing
Responsibilities

Generic Name
: Dobutamine




Brand Name:
Dobutrex


Vasopressors

a direct-acting agent
whose primary activity
results from stimulation of
the
1
-adrenoceptors of
the heart, increasing
contractility and cardiac
output. Since it does not
act on dopamine
receptors to induce the
release
of norepinephrine (another

1
agonist), dobutamine is
less prone to induce
hypertension than
is dopamine.

This medication
is a
sympathomimetic
compound used
in the treatment
of heart failure
and cardiogenic
shock. It
stimulates the
heart muscle.


Contraindicated in
patients with
hypersensitivity;
idiopathic
hypertrophic
subaortic stenosis
(Obstruction of
the flow of blood
out of the left
ventricle due to
enlargement of
the ventricular
septum),
Tachydsrhythmias.



Heart-
Increased heart
rate and blood
pressure, chest
pain,
palpitation.
Local-
Inflammation of
vein.
Miscellaneous-
Nausea,
vomiting,
headache,
anxiety, fatigue
and shortness
of breath
Potentially
Fatal- Heart
diseases.


Observe IV site
closely and avoid
extravasation.
Dobutamine can
cause
inflammatory
response and
tissue ischaemia.
Monitor for
adverse reactions
Continuous
blood pressure
monitoring
Continuous
cardiorespiratory
monitoring
Document vital
signs hourly and
PRN
Monitor fluid
balance





Kitia Mae C. Pepito BSN4Y1-8B


DRUG


Classification

Action

Indication

Contraindication

Adverse effects

Nursing
Responsibilities
.

Generic Name:
Hydrocortisone

Brand Name:
Cortef,
Hydrocortone

Anorectal
Preparations

Enters target cells
and binds
to cytoplasmic recep
tors; initiates many
complex reactions
that are responsible
for its anti-
inflammatory,
immunosuppressive
(glucocorticoid), and
salt-retaining
(mineralocorticoid)
actions. Some
actions may be
undesirable,
depending on drug
use.

This medication
is a
corticosteroid,
prescribed for
severe allergies,
arthritis, asthma,
multiple sclerosis
and skin
conditions. It is
also used to treat
certain types of
cancer.



Contraindicated in
patients with
systemic fungal
infection, who are
taking mifepristone
and
hypersensitivity.



headache
nausea
vomiting
dizziness
insomnia
restlessness
depression
anxiety
unusual moods
increased
sweating
increased hair
growth
reddened face
acne
thinned skin
easy bruising
tiny purple skin
spots
irregular or
absent menstrual
periods


WARNING: Give daily
before 9 AM to mimic
normal peak diurnal
corticosteroid levels
and minimize HPA
suppression.
Space multiple
doses evenly
throughout the day.
Do not give IM
injections if patient has
thrombocytopenic pur
pura.
Rotate sites of IM
repository injections to
avoid local atrophy.
Use minimal
doses for minimal
duration to minimize
adverse effects.
Taper doses when
discontinuing high-
dose or long-term
therapy.
Arrange for
increased dosage when
patient is subject to
unusual stress.