The Binding of Isaac has 97 Secrets (As of Wrath of the Lamb v1.48) that can be unlocked.

Secrets can add differents kinds of things to

the game, such as Items, Bosses, Characters, etc.
In-Game Secrets List (98)
Basic Progression Unlocks
"A Radioactive Spider" - Finish
The Basement. (Collectible item)
"Spelunker" - Finish The Caves.
(Collectible item)
"The Womb" - Finish The Depths.
(Opens level/chapter)
"Monstro's Tooth" - Defeat every
regular boss from The Basement.
(Activated item)
"Lil Chubby" - Defeat every regular
boss from The Caves. (Collectible
item)
"Loki's Horns" - Defeat every
regular boss from The Depths.
(Collectible item)
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Character and Combo Unlocks
"Cain" - Get 55 pennies in a
single playthrough. (Playable
Character)
"The Lucky Foot" - Get 55 pennies
in a single playthrough.
(Collectible item)
"Magdalene" - Get 7 health
containers in a single playthrough.
(Playable Character)
"The Yum Heart" - Get 7 health
containers in a single
playthrough. (Activated item)
"Judas" - Defeat the boss in The
Womb 2 for the rst time.
(Playable Character)
"The Book of Belial" - Defeat the
boss in The Womb 2 for the rst
time. (Activated item)
"???" - Defeat the boss in The
Womb 2 for the tenth time.
(Playable Character)
"A Poop" - Defeat the boss in The
Womb 2 for the tenth time.
(Activated item)
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Game Completion Unlocks
"A Noose" - Defeat the boss in
The Womb 2 for the second time.
(Collectible item)
"The Nail" - Defeat the boss in The
Womb 2 for the third time.
(Activated item)
"A Quarter" - Defeat the boss in
The Womb 2 for the fourth time.
(Collectible item)
"A Fetus In A Jar" - Defeat the
boss in The Womb 2 for the fth
time. (Collectible item)
Contents
Secrets
"Everything is Terrible!!!" - Defeat
the boss in The Womb 2 for the
sixth time. (Difculty Increase)
"The Wafer" - Defeat the boss in
The Womb 2 for the seventh time.
(Collectible item)
"Money = Power" - Defeat the
boss in The Womb 2 for the eighth
time. (Collectible item)
"It Lives!" - Defeat the boss in The
Womb 2 for the ninth time. (New
Boss)
"A Cross" - Defeat the boss in The
Womb 2 with Magdalene.
(Collectible item)
"A Bag of Pennies" - Defeat the
boss in The Womb 2 with Cain.
(Collectible item)
"A Robo-Baby!" - Defeat the boss
in The Womb 2 with Judas.
(Collectible item)
"The D6" - Defeat the boss in The
Womb 2 with ???. (Activated item)
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Special Bosses and Loot
"Something from the Future!" -
Finish the Basement 25 times.
(New Boss)
"Little Steve" - Defeat Steven
(alternate boss). (Collectible item)
"Something Cute" - Finish the
Caves 20 times. (New Boss)
"Little C.H.A.D." - Defeat C.H.A.D.
(alternate boss). (Collectible item)
"Something Sticky" - Finish the
Depths 30 times. (New Boss)
"Little Gish" - Defeat Gish
(alternate boss). (Collectible item)
"The Harbingers" - Defeat the
Boss in The Depths 2. (New
Bosses)
"The Book of Revelations" -
Defeat any Harbinger/Horseman.
(Activated item)
"A Cube of Meat" - Defeat the
Boss in The Depths 2. (Collectible
item)
"The Book of Sins" - Defeat all of
the Seven Deadly Sins over
multiple playthroughs. (Activated
item)
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Separate Task Based
"A Small Rock" - Destroy 50 tinted
rocks ( ) over multiple
playthroughs. (Collectible item)
"Mr. Mega!" - Destroy 10 tinted
rocks ( ) over multiple
playthroughs. (Collectible item)
"A Halo" - Defeat the Boss in The
depths 2 (Mom) by using the
Bible. (Collectible item)
"Mom's Contact" - Collect Moms
eye and another Mom item in the
same playthrough. (Collectible
item)
"A Gamekid" - Visit Arcades
enough times over multiple
playthroughs. (Activated item)
"Mom's Pill Bottle" - Use several
Blood Donation Machines in
multiple playthroughs. (Activated
item)
"The Common Cold" - Collect any
two of the following: Roid Rage,
The Virus, and Growth Hormones,
in the same playthrough.
(Collectible item)
"A Bandage" - Make a Meat Boy
(obtain 4 Cubes of Meat in the
same playthrough) (Collectible
item)
"The Necronomicon" - Use the
Death Card ( ) 4 times over
multiple playthroughs. (Activated
item)
"The Parasite" - Collect two "dead
things" (Bob's Rotten Head, Dead
Cat, Max's Head, Tammy's Head)
in a single playthrough.
(Collectible item)
"The Pinking Shears" - Die 100
times. (Activated item)
"The Bean" - Destroy 50 piles of
poop over multiple
playthroughs. (Activated item)
"A Lump of Coal!?" - Defeat
Krampus. (Collectible item)
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No Damage Achievements
"Basement Boy" - Finish the two
Basement/Cellar levels without
taking any damage. (You just need
to kill the bosses, you don't have
to clear all of the rooms).
"Spelunker Boy" - Finish the two
Caves/Catacombs levels without
taking any damage. (You just need
to kill the bosses, you don't have
to clear all of the rooms).
"Dark Boy" - Finish the two
Depths/Necropolis levels without
taking any damage. (You just need
to kill the bosses, you don't have
to clear all of the rooms).
"Mama's Boy" - Finish the
Womb/Utero levels without taking
any damage. (You just need to kill
the bosses, you don't have to
clear all of the rooms).
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Halloween Update
"The Razor" - Finish The Womb
with Eve. (Activated item)
"Mom's Knife" - Kill Satan with
Isaac. (Collectible Item)
"Eve" - Make 2 Separate Devil
Room Deals in one playthrough.
(Playable Character)
"A Curse" - Make 2 Separate Devil
Room Deals in one playthrough.
(Collectible Item)
"The Monster Manuel" - Kill Satan
with Judas. (Activated Item)
"A Dead Bird" - Make 2 Separate
Devil Room Deals in one
playthrough. (Collectible Item)
"A Bag of Bombs" - Kill Satan with
Cain. (Collectible Item)
"Guardian Angel" - Kill Satan with
Maggy. (Collectible Item)
"A Demon Baby!" - Kill Satan with
Eve. (Collectible Item)
"A Forget Me Now" - Kill Satan
with ???. (Activated/Consumable
Item) [Takes up your item slot and
dissapears when used]
"Golden God!" - Unlock all secrets
and complete the Collection.This
achievement can be gained by
collecting all but one of the items if
you have defeated Krampus and
found the lump of coal.
Title screen with Golden God
achievement unlocked.
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Wrath of the Lamb In-Game Secrets List (34)
Characters
"Samson" - Complete Depths 2,
but pass on 2 Treasure Rooms.
(Playable Character)
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Game Completion Unlocks
"The D20!" - Complete the
Cathedral as Isaac. (Activated
Item)
"The Crucix" - Complete the
Cathedral as Maggy. (Collectible
Item)
"Abel" - Complete the Cathedral
as Cain. (Collectible Item)
"Curved Horn" - Complete the
Cathedral as Judas. (Trinket)
"Sacricial Knife" - Complete the
Cathedral as Eve. (Collectible
Item)
"Rainbow Baby <3"Complete the
Cathedral as ???. (Collectible
Item)
"Bloody Lust" - Complete Womb 2
as Samson. (Collectible Item)
"Blood Rights" - Complete Sheol
as Samson. (Activated Item)
"Bloody Penny" - Complete the
Cathedral as Samson. (Trinket)
"The Polaroid" - Complete the
Cathedral six times. (Trinket)
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The Chest
"Isaac's Head" - Complete The
Chest as Isaac. (Trinket)
"Maggy's Faith" - Complete The
Chest as Maggy. (Trinket)
"Cain's Eye" - Complete The
Chest as Cain. (Trinket)
"Judas' Tongue" - Complete The
Chest as Judas. (Trinket)
"Eve's Bird Foot" - Complete The
Chest as Eve. (Trinket) [V 1.48:
Unlocked by completing the Chest
as ??? instead]
"???'s Soul" - Complete The Chest
as ???. (Trinket) [V 1.48: Unlocked
by completing the Chest as Eve
instead]
"Samson's Lock" - Complete The
Chest as Samson. (Trinket)
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Challenges
"The Candle" - Complete
Challenge 1. (Activated item)
"Lucky Toe!" - Complete
Challenge 2. (Trinket)
"Burnt Penny" - Complete
Challenge 3. (Trinket)
"Guppy's Tail" - Complete
Challenge 4. (Collectible item)
"A Fish Head" - Complete
Challenge 5. (Trinket)
"Mega Fetus" - Complete
Challenge 6. (Collectible item)
"Super Fan" - Complete Challenge
7. (Collectible Item)
"Spider Butt" - Complete
Challenge 8. (Activated item)
"Counterfeit Coin" - Complete
Challenge 9. (Trinket)
"The Egg Sack" - Complete
Challenge 10 (Collectible item)
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Task Based
Categories: Wrath of the Lamb Pages needing improvement
The Binding of Isaac PSA 1 - Missing Secrets Fix
"Guppy's Hairball" - Transform
Isaac into Guppy. (Collectible
item)
"Dad's Key" - Complete the Chest
with any character. (Activated
item)
"!Platinum God!" - Collect 197
items and unlock all other 97
secrets.
"A Forgotten Horseman" - Destroy
a total of 30 Tinted Rocks. (New
Boss - Conquest)
"Something Icky!" - Complete the
Womb or Utero 15 times. (New
boss - Triachnid)
"The Left Hand" - Unlocked by
defeating Ultra Pride. (Trinket)
"Stop Playing!" - Kill Mom over
200 times (New backdrop).
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Bugs
Secrets might be missing even though they have already been earned, due to various Anti-Virus programs, CCleaner (Or similar cleaner programs) or Steam's Cloud
Sync.
For a detailed description on how to x the missing secrets, check the video below.
Videos
Discussions about Secrets
See more discussions >
09:41
Start a Discussion
Missing an achievement I know I have obtained?
3 messages
A Wikia contributor
nope not that i know of but best to reinstall the hole game and hope that you get the achivment or holpe that it is patched in the tboi:rebirt...
Huffpuff1337
No, dummy. Right click on The Binding Of Isaac, go to Properties, go to Local Files and click Verify Integrity of Game Cache. This should work,...
Golden God Bug?
5 messages
A Wikia contributor
what is WotL because this is the binding of issac wiki?
A Wikia contributor
WotL is the expansion pack, Wrath of the Lamb