DRUG ORDER

MECHANISM
OF ACTION
INDICATIONS
CONTRAINDICATIONS
ADVERSE
EFFECTS OF THE
DRUG
NURSING
RESPONSIBILITIES/
PRECAUTIONS
Generic
Name:
omeprazole
Brand Name:
Omepron
Classification:
Proton pump
inhibitors
Dosage:
40mg 1tab
Route: PO
Frequency:
QHS
Gastric acid-
pump
inhibitor.
Suppresses
gastric acid
secretion by
specific
inhit=bition of
the hydrogen-
potassium
ATPase
enzyme
system at the
secretory
surface of the
gastric parietal
cells; blocks
final step of
acid
production.
Short
term
treatment
for
duodenal
ulcer.
Treatment
of
heartburn
or
symptoms
of GERD.
Short
term
treatment
of active
benign
gastric
ulcer.
GERD,
severe
erosive
esophagiti
Hypersensitivity

Use cautiously with
pregnancy and
lactation.
CNS: headache,
vertigo,
insomia,anxiety,
apathy

DERM: rash,
inflammation,
pruritus, dry
skin

GI: diarrhea,
abdominal pain,

RESP: URI
symptoms,
sough, eistaxis

CV: chest pain
- Monitor BP
during periods
of diuresis and
through period
of dosage
adjustment.
- Administer
before meals.
Caution patient
to swallow
whole not to
open, chew, or
crush them.
- Administer
antacids if
needed.
- Advise patient
to avoid
alcohol,
products
containing
aspirin or
NSAIDs, and

s, poorly
responsiv
e
symptom
atic GERD.
foods that may
cause an
increase in GI
irritation.
DRUG ORDER
MECHANISM OF
ACTION
INDICATIONS
CONTRAINDICATIO
NS
ADVERSE
EFFECTS OF THE
DRUG
NURSING
RESPONSIBILIT
IES/
PRECAUTIONS
Generic Name:
Pregabalin
Brand name:
Lyrica
Classification:
Anticonvulsants
or
Antiepileptics
Dosage: 50mg 1
tap
Route: PO
Frequency: QHS
In vitro studies
show that
pregabalin binds
to an auxiliary
subunit (
2
-
protein) of
voltage-gated
calcium channels
in the central
nervous system,
potently
displacing [3H]-
gabapentin. Two
lines of evidence
indicate that
binding
Treatment of
neuropathic pai
n in adults.
Hypersensitivity to
pregabalin or to
any of the
excipients of
Lyrica.
GI disturbances:
nausea &
vomiting, fatigue,
dizziness.
EYE:Blurred
vision, diplopia.
Visual
disturbance, dry
eye, eye swelling,
reduced visual
acuity, eye pain,
asthenopia,
increased
lacrimation.Phot
opsia, eye
irritation,
-Advice the
patient not to
immediately
stand up may
cause
dizziness.
- Monitor vital
signs
continously
and cardiac
status.
- May be taken
with or
without food.
pregabalin to the

2
- site is
required for
analgesic and
anticonvulsant
activity in animal
models: (1)
Studies with the
inactive R-
enantiomer and
other structural
derivatives of
pregabalin and (2)
Studies of
pregabalin in
mutant mice with
defective drug
binding to the
2
-
protein. In
addition,
pregabalin
reduces the
release of several
neurotransmitters
, including
glutamate,
noradrenaline
mydriasis,
oscillopsia,
altered visual
depth
perception,
peripheral vision
loss, strabismus,
visual brightness.
EAR: Vertigo,
Hyperacusis.
CARDIO:Tachycar
dia, First-degree
atrioventricular
block, sinus
tachycardia,
sinus arrhythmia,
sinus
bradycardia.

and substance P.
The significance
of these effects
for the clinical
pharmacology of
pregabalin is not
known.
DRUG ORDER
MECHANISM OF
ACTION
INDICATIONS
CONTRAINDICATIONS
ADVERSE
EFFECTS OF
THE DRUG
NURSING
RESPONSIBILITIES/
PRECAUTIONS
Generic Name:
Co-Amoxiclav
Brand Name:
Antrodav
Classification:
Proton pump
inhibitors
Dosage: 1.2mg
Route: IV
Frequency:
upon induction
of anesthesia
An antibiotic
that combines
amoxicillin and
clavulanic acid.
It destroys
bacteria by
disrupting their
ability to form
cell walls.
Co-amoxiclav is
active against
bacterial
infections that
have become
resistant to
Known or
suspected
amoxicillin-
resistant
infections
including
respiratory
tract, skin and
soft tissue,
genitourinary,
and ear, nose
and throat
infections.
Effective
against strains
Penicillin
hypersensitivity.
History of co-
amoxiclav-associated
or penicillin-
associated jaundice or
hepatic dysfunction
Lethargy,
hallucinations,
seizures,
glossitis, sore
mouth, furry
tongue, black
hairy tongue,
nausea and
vomiting,
diarrhea,
abdominal
pain, bloody
diarrhea,
enterocolitis
Assess bowel
pattern before and
during treatment
as pseudo
membranous
colitis may occur.
>Report hematuria
or oliguria as high
doses can be
nephrotoxic.
>Assess
respiratory status.
>Observe for
anaphylaxis.
- >Ensure that


amoxicillin of Escherichia
coli, Proteus
mirabilis,
Haemophilus
influenza,
Streptococcus
faecalis,
Streptococcus
pneumoniae
and some
beta-
lactamase-
producing
organisms.
the patient has
adequate fluid
intake during
any diarrhea
attack.
-