1.

In double helix of DNA, the two strands are

A. Coiled around a common axis
B. Coiled differently
C. Coiled over protein sheath
D. Coiled around each other
2. Lipids are insoluble in water because lipid molecules are
A. Hydrophilic
B. Neutral
C. Zwitter ions
D. Hydrophobic
3. Lactose is composed of
A. Glucose + galactose
B. Fructose + galactose
C. Glucose + fructose
D. Glucose + glucose
4. Which of the following nucleotide sequences contains four pyrimidine bases?
A. GATCAATGC
B. UAGCGGUAA
C. GCUAGACAA
D. Both B and C
5. The term apoenzyme is applicable to
A. Simple enzyme
B. Protein part of conjugate enzyme
C. Organic cofactor of a conjugate enzyme
D. Inorganic cofactor of conjugate enzyme
6. The enzymes involved in feed back inhibition are called
A. Allosteric enzymes
B. Holoenzymes
C. Apoenzymes
D. Coenzymes
7. Koshlands theory of enzyme action is known as
A. Reduced fit theory
B. Induced fit theory
C. Lock and key theory
D. Enzyme coenzyme theory
8. Which of the statements is true regarding Km
A. It is the measure of the stability of the ES complex
B. It is the measure of the stability of the affinity of an enzyme for its substrate
C. A high Km indicates weak substrate binding
D. All of these
9. Any molecule which acts directly on an enzyme to lower its catalytic rate is called
A. Regulator
B. Repressor
C. Inhibitor
D. Moderator
10. A reversible non-competitive inhibitor binds reversibly at a site other than the active site. This
binding lead to
A. increase in Km and Vmax remains constant
B. Increase in Vmax and Km remain constant
C. Decrease in Vmax and Km remains constant
D. No change in Vmax and Km

11. The preferred substrate for hexokinase is
A. Glucose
B. Fructose
C. Glucose and fructose equally preferred
D. Galactose
12. The primary structure of protein represents
A. Linear sequence of amino acids joined by peptide bond
B. 3 dimensional structure of protein
C. Helical structure of protein
D. Sub unit structure of protein
13. The first protein sequence by Fredrick Sanger is
A. Haemoglobin
B. Myoglobin
C. Myosin
D. Insulin
14. A. dipeptide has
A. 2 amino acids and 1 peptide bond
B. 2 amino acids and 2 peptide bonds
C. 2 amino acids and no peptide bonds
D. 2 amino acids and release of two water molecules
15. helix has
A. 3.4 amino acid residue/turn
B. 3.6 amino acid residue/turn
C. 3.8 amino acid residue/turn
D. 3.0 amino acid residue/turn
16. The pentoses in nucleotides are
A. In furnaose form
B. In furanose form
C. Both alpha and beta form
D. In pyrnaose form
17. Dehydration of DNA samples may induce the formation of
A. A DNA
B. Z- DNA
C. B-DNA
D. H-DNA
18. Ribozymes are
A. Enzymes with catalytic activity
B. RNA with catalytic activity
C. Proteins with catalytic activity
D. Nucleic acids with catalytic activity
19. A nucleoside is composed of
A. A base + sugar
B. A base + sugar + phosphate
C. A base + phosphate
D. Sugar + phosphate
20. The length of one turn of DNA is
A. 3.4 A
0

B. 34 A
0

C. 20 A
0

D. 3.04 A
0

21. A short length of DNA molecule has 80 thymine and 80 guanine bases. The total number of
nucleotide in the DNA fragment is
A. 160
B. 40
C. 320
D. 640
22. The synthesis of glucose from fat is called
A. Glycolysis
B. Krebs cycle
C. Glycogenesis
D. Gluconeogenesis
23. oxidation takes place in
A. mitochondria
B. Cytoplasm
C. Chlroplasts
D. Nucleus
24. Which of the following monosaccharides is not an aldose?
A. Galactose
B. Glucose
C. Fructose
D. Ribose
25. Which of the following is an epimeric pair?
A. D-glucose and D-glucosamine
B. D-glucose and D-mannose
C. D-lactose and D-sucrose
D. L- mannose and L- fructose
26. When the linear form of glucose cyclizes, the product is a(n):
A. Anhydride
B. Glcyoside
C. Hemiacetal
D. Lactone
27. Which of the following is not a reducing sugar?
A. Fructose
B. Glucose
C. Glyceraldehyde
D. Sucrose
28. Which of the following amino acid has amide group in its side chain ?
A. cysteine
B. Lysine
C. Glutamine
D. Isoleucine
29. Which of the following amino acid is a alpha helix terminator?
A. Tryptophan
B. Phenyl alanine
C. tyrosine
D. Proline
30. The naturally occurring form of amino acid in proteins
A. L amino acids only
B. D amino acids only
C. Both L and D amino acids
D. None of these









IMMUNOLOGY AND MEDICAL BIOTECHNOLOGY
1. The molecule or substance which induces detectable immune response (humoral /cellular
mediated immune response) is called as
A. Antibody
B. Immunogen
C. MHC
D. Antigen
2. Which among the following is called as C5 convertase in classical pathway?
A. C3bBb
B. C4b2b
C. C3bBb3b
D. C4b2a3b
3. A patient is suffering from the defect in thymic development resulted from a presumed failure
of the neural crest mesenchyma to induce morphogenetic changes in the third pharyngeal
pouch derived endoderm. The patient is suffering from which among the following
immunological disease?
A. DiGeorge syndrome
B. Graves disease
C. X-gammaglobulinemia
D. Mysthenia Gravis
4. The smallest portion of antigen which act as immunogen is called as
A. Paratope
B. Allotope
C. Epitope
D. Isotope
5. Which among the following is called as secretory antibody?
A. IgG
B. IgA
C. IgD
D. IgM
6. If a particulate antigen reacts with soluble antibody leads to _______ reaction.
A. Precipitation
B. Neutralization
C. Agglutination
D. Flocculation
7. Who among the following discovered the human blood group systems?
A. Alexis Carrel
B. Karl Landsteiner
C. Jules Bordet
D. Robert Koch
8. The strength of the total non-covalent interactions between a single antigen binding site on an
antibody is called as
A. Valency
B. Affinity
C. Avidity
D. Cross reactivity
9. Two separate arcs crossing each toher when dissimilar antigen are reacting with antibody by
double diffusion method or experiment is
A. Identity
B. Partial identity
C. Non identity
D. None of the above
10. An enzyme conjugated with an antibody reacts with a colourless substrate to generate a
coloured reaction is the basic principle lies behind ____.
A. ELISA
B. RIA
C. ODD
D. RIE
11. The target organ that affected in Mysthenia Gravis is
A. Thyroid
B. Skin
C. Kidney
D. Muscle
12. The immunological reaction, which is mediated by the formation of soluble immune complexes
and subsequent activation of complements on the cellular matrix is grouped as
A. Type I hypersensitivity reactions
B. Type II hypersensitivity reactions
C. Type III hypersensitivity reactions
D. Type IV hypersensitivity reactions
13. Epstein Barr Virus (EBV), Human papilloma Virus (HPV) are very important virus in the
development of
A. Cancers or tumors
B. Tolerance to immune system
C. Immuno-resistance
D. Autoimmune diseases
14.