Patient Information Leaflet

Co-Amoxiclav 375mg and 625mg Tablets

What you should know about this medicine. Please read this leaflet carefully before you start to take these tablets.
If there is something you dont understand, or if you have any other questions remember to ask your pharmacist or
doctor. Keep this leaflet, you may want to read it again.

The name of this medicine is Co-amoxiclav Tablets These tablets are available in t!o strengths
o!amo"iclav #ablets $%&mg are pale yellow, biconve" tablets embossed $%& on one side. #he tablets contain two
active ingredients, '&(mg of amo"icillin )as trihydrate* and +'&mg clavulanic acid )as potassium clavulanate*.
)#hese ingredients together are known as o!amo"iclav*.

o!amo"iclav #ablets ,'&mg are pale yellow, oblong, biconve" tablets embossed ,'& on one side. #he tablets
contain &((mg of amo"icillin )as trihydrate* and +'&mg clavulanic acid )as potassium clavulanate*.
-oth strengths of tablets also contain microcrystalline cellulose, quinoline yellow ).+(/*, titanium dio"ide ).+%+*,
crospovidone, Povidone K'&, colloidal silicon dio"ide, stearic acid, polyethylene glycol ,(((,
methylhydro"ypropylcellulose, saccharin sodium, vanilla flavour and magnesium stearate.
o!amo"iclav #ablets $%&mg and o!amo"iclav #ablets ,'&mg are available as packs of '+ tablets.

"o! does this medicine !or#$
0mo"icillin is an antibiotic. 0ntibiotics are used to treat infections caused by bacteria. When amo"icillin is
combined with clavulanic acid it is effective against a wider range of bacteria than when used alone.

Prod%ct Licence "older&
0thlone Pharmaceuticals 1imited, -allymurray, o. 2oscommon, Ireland
'an%fact%red b(&
ime" 03, -irsweg ', 4!/'&$ 1iesburg, 5wit6erland.


)istrib%ted b(&
5overeign 7edical, 5overeign 4ouse, 7iles 3ray 2oad, -asildon, .sse" 55+/ $82.

*h( am I ta#ing Co-amoxiclav Tablets$
#hey are used to treat respiratory tract infections such as bronchitis, pneumonia, sinusitis, tonsillitis and middle ear
infections9 infections of the kidneys, abdomen and lower urinary tract including cystitis9 and skin and tissue
infections.

'a#e s%re that it is safe for (o% to ta#e these tablets
5ometimes it may not be suitable. :ou should check with your doctor if;
you are sensitive or allergic to o!amo"iclav #ablets or any of the ingredients, or to penicillin or other
antibiotics
you have ever developed serious liver problems when taking an antibiotic,
you are pregnant, trying to become pregnant, or breast!feeding,
you have liver or kidney problems,
you have glandular fever,
you are on a low potassium diet.
5ome drugs will inteefere with the action of o!amo"iclav. #ell your doctor if you are taking any of these
medicines
other antibiotics such as chloramphenicol, erythromycin, sulfonamides, or tetracyclines,
warfarin or other drugs to prevent blood clotting. #he effect of drugs to thin the blood such as warfarin may be
increased by o!amo"iclav. If this happens there could be a risk of e"cessive bleeding.
0llopurinol or probenecid for gout and related conditions.

Co-amoxiclav Tablets 375mg and 625mg contain 2+6mg ,otassi%m and so ma( be harmf%l to ,eo,le !ho
need to be on a lo! ,otassi%m diet
Co-amoxiclav Tablets do not interact !ith oral contrace,tives and (o% sho%ld %se other methods of
contrace,tion !hilst ta#ing these tablets

:ou should always let your doctor know what other medicines you are taking, including any that have been
prescribed by your doctor or you have bought.


Ta#ing (o%r medicine
#ake at regular intervals. omplete the prescribed course unless otherwise directed.
:ou should always take these tablets as prescribed by your doctor. #he instructions are usually on the pharmacists
label. If youre not sure about anything please ask your doctor or pharmacist.

For infections:
)osage for ad%lts -incl%ding the elderl(. and children over /2&
The %s%al dose is 375mg three times a da(0 ,referabl( ever( 1 ho%rs0 for a maxim%m of /+ da(s
For more severe infections:
2ne 625mg tablet three times a da(
For dental infections:
The %s%al dose is 375mg three times a da(0 ,referabl( ever( 1 ho%rs0 for 5 da(s

#he dose for people with severe liver or kidney problems may be less than these doses. #he doctor will have
decided what dose you need.

#hese tablets are not suitable for children under +' or weighing less than /(kg.
<o not take more tablets than the doctor told you to take. #ake the tablets for as long as the doctor told you to.
<o not stop taking them because you feel better.
If you are still unwell after finishing the course of tablets go and see your doctor.
5wallow the tablets with a drink at the beginning of a meal. <o not break or chew the tablets.

If (o% forget to ta#e a tablet take one as soon as you remember, then carry on with the ne"t dose.
#ry to wait about / hours before taking the ne"t dose, and do not take two doses within about one hour or so.
=ever double!up on the dose to make up for the one you have missed.

If you take too many tablets tell your doctor or the nearest hospital casualty department straight away. 1et people
know what you have taken.

Are there an( side-effects$
7ost people do not have any problems when they take these tablets, but nearly all medicines can cause side!effects
in some people.
o!amo"iclav #ablets can sometimes cause stomach problems such as nausea )feeling sick*, vomiting, indigestion
or diarrhoea. #hese symptoms are usually mild and can be reduced by taking the tablets at the beginning of a meal.
>ery rarely, some people e"perience hyperactivity, di66iness, headache and convulsions. #hese symptoms are
reversible.
#here have been rare reports of tooth discolouration. #his can usually be removed by brushing.
5ome people may get thrush )a yeast infection of the vagina or mouth* when they take these tablets.
:ou can get treatments for thrush from your pharmacist or doctor. If you notice anything else which you dont
understand ask your doctor or pharmacists advice.

5ome people can be allergic to antibiotics and can develop a rash. #his can range in severity from a mid itchy rash
to a rarer more serious condition which may cause ulceration of the mouth, lips and skin. Inflammation of the
kidney can also occur rarely. In very rare cases, allergic reactions can include difficulty in breathing, fainting or
swelling of the face and throat. 5top taking the tablets and tell your doctor if you develop any of these symptoms.

5ee your doctor immediately if you develop any of the following either while you are taking o!amo"iclav #ablets
or in the weeks after finishing the treatment.
5evere or prolonged diarrhoea with bleeding
<arker urine or paler faeces
:our skin or eyes becoming yellow
8ever, bruising or bleeding.

o!amo"iclav #ablets can sometimes affect blood cell counts. 7ake sure that your doctor knows that you are
taking these tablets if you are having blood tests.

"o! to #ee, (o%r tablets

3ee, all medicines in a safe ,lace a!a( from children
<o not store above '&o. 5tore in the original package in order to protect from moisture. Keep the container
tightly closed.
<o not take the tablets after the date shown on the pack.

45'5'654 this medicine was prescribed for you. :ou should not give it to anyone else even if you think their
symptoms are similar. It may harm them.