31-10-2014

31
st
October, 2014 Volume No.: 38 Issue No.: 04
Vision
TO REACH THE PINNACLE OF GLORY AS A CENTRE OF EXCELLENCE IN THE FIELD
OF PHARMACEUTICAL AND BIOLOGICAL SCIENCES BY KNOWLEDGE BASED
LEARNING AND PRACTICE
Contents
Message from PRINCIPAL
Editorial board
Historical article
News Update
Knowledge based Article
Disease Related Breaking
News
Upcoming Events
Drugs Update
Campus News
Students Section
Editors Note
Archive
GNIPST Photo Gallery
For your comments/contribution
OR For Back-Issues,
mailto:gnipstbulletin@gmail.com
GURU NANAK INSTITUTE OF PHARMACEUTICAL
SCIENCE AND TECHNOLOGY

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31-10-2014
MESSAGE FROM PRINCIPAL

"It can happen. It does happen.
But it can't happen if you quit." Lauren Dane.
We are what we repeatedly do.
Excellence then is not an act, but a habit. Aristotle
It gives me immense pleasure to pen a few words for our e-bulletin. At the onset I would like to thank the
last years editors and congratulate the newly selected editors for the current year.
Our first consideration is always in the best interest of the students. Our goal is to promote academic
excellence and continuous improvement.
I believe that excellence in education is aided by creating a learning environment in which all learners are
supported in maximizing their potential and talents. Education needs to focus on personalized learning
and instruction, while promoting an education system that is impartial, universally accessible, and meeting
the needs of all students.
It is of paramount importance that our learners have sufficient motivation and encouragement in order to
achieve their aims. We are all very proud of you, our students, and your accomplishments and look
forward to watching as you put your mark on the profession in the years ahead.
The call of the time is to progress, not merely to move ahead. Our progressive Management is looking
forward and wants our Institute to flourish as a Post Graduate Institute of Excellence. Steps are taken in
this direction and fruits of these efforts will be received by our students in the near future. Our Teachers
are committed and dedicated for the development of the institution by imparting their knowledge and play
the role of facilitator as well as role model to our students.
The Pharmacy profession is thriving with a multitude of possibilities, opportunities and positive
challenges. At Guru Nanak Institute of Pharmaceutical Science and Technology, our focus is on holistic
needs of our students.
I am confident that the students of GNIPST will recognize all the possibilities, take full advantage of the
opportunities and meet the challenges with purpose and determination.
Excellence in Education is not a final destination, it is a continuous walk. I welcome you to join us on
this path.
My best wishes to all.
Dr. A. Sengupta
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EDITORIAL BOARD
CHIEF EDITOR DR. ABHIJIT SENGUPTA
EDITOR MS. JEENATARA BEGUM
ASSOCIATE EDITOR MR. DIPANJAN MANDAL
HISTORICAL ARTICLE
Sardar Vallabhbhai Patel:
Sardar Patel the iron-man of India was one of Mohandas Gandhis
closest associates, and he organized and led several satyagrahas
during Indias struggle for freedom from British rule. When India
achieved independence in 1947, Patel became Home Minister and
Deputy Prime Minister, and he presided over the most difficult
task facing the nascent nation-state, namely the integration of over
500 princely states into the Indian Union.
Vallabhbhai Patel was born in Nadiad in present-day Gujarat in
1875. He completed his schooling in the local area and
subsequently, in his 30s, he went to Britain; like many of his
generation of political leaders, he qualified as a barrister. Patel
returned to India around the same time as Gandhi returned to India
from South Africa, on the eve of World War I, and the two met
shortly thereafter. Patel joined Gandhi in representing the weavers
in the dispute with millowners in Ahmedabad in 1918, and he
played a pivotal role in helping to redress the grievances of
peasants in Kheda district. "I will say", wrote Gandhi in his
autobiography, "that without the help of Vallabhbhai Patel, we
should not have won the campaign. He had a splendid [law]
practice, he had his municipal work to do, but he renounced it all
and threw himself in the campaign."
In 1930 Sardar Vallabhbhai Patel was imprisoned for participating
in the famous Salt Satyagraha called by Mahatma Gandhi. His
inspiring speeches during the "Salt Movement" transformed the
lives of numerous people, who later played a major role in making
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the movement successful.
Sardar Patel was freed in 1931 following an agreement signed
between Mahatma Gandhi and Lord Irwin, the then Viceroy of
India. The treaty was popularly known as the Gandhi-Irwin pact.
The same year, Patel was elected as the president of Indian
National Congress Party for its Karachi session.
In the Karachi session, the Indian National Congress Party
committed itself to the defence of fundamental rights and human
rights and a dream of a secular nation. An agreement regarding this
was also sanctioned.
In 1934, Sardar Vallabhbhai Patel led the all-India election
campaign for the Indian National Congress. Though he did not
contest a seat for himself, Sardar Patel helped his fellow party
mates during the election.
Sardar Patel was annoyed at Jawaharlal Nehru for the latter's
declarations of the adoption of socialism in 1936. Patel also
considered Netaji Subhash Chandra Bose a "keen of more power
within the party.
Sardar Vallabhbhai Patel's health declined in 1950. He, himself
realized that he was not going to live much longer. On 2 November
his health deteriorated further and was confined to bed. After
suffering a massive heart attack, on 15 December 1950, the great
soul left the world.
NEWS UPDATE
High prevalence of vitamin D deficiency across
the board in neuromuscular disease: (31
st

October, 2014)
More credence has been added to a growing awareness of
the high prevalence of vitamin D deficiency in
neuromuscular disease by newly presented research.
Vitamin D supplementation has been suggested to improve
function in frail elderly patients at risk for falls, as well as
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individuals with myasthenia gravis and Parkinson's. The
impact of vitamin D deficiency and supplementation on
function in other neurologic conditions has yet to be
explored.
Digital Therapist: Computer program analyzes
speech, mental health: (31
st
October, 2014)
A program that analyzes your speech and uses it to gain
information about your mental health could soon be feasible,
thanks in part to new research showing that certain vocal features
change as patients feelings of depression worsen.
Researchers probe link between newborn health,
vitamin A: (30
th
October, 2014)
The impact vitamin A has on newborns is virtually unknown, but
nutrition researchers have published two papers that may provide
a framework for future investigations of the vitamin and neonatal
health.
Unlocking the secrets of pulmonary hypertension:
(30
th
October, 2014)
A protein that plays a critical role in metabolism, the process by
which the cell generates energy from foods, is important for the
development of pulmonary hypertension, a deadly disease.
Pulmonary hypertension is caused by the narrowing of the blood
vessels in the lung, due to excessive growth of cells in the blood
vessel wall. The cells grow in number until they obstruct the
vessels, causing the heart to struggle pushing blood through the
lungs to the point where the heart fails and the patient dies.
Doubt cast over air pollution link between
childhood leukemia, power lines: (30
th
October,
2014)
Researchers from the UK have called into question a theory
suggesting that a previously reported risk of leukemia among
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children born close to overhead power lines could be caused by an
alteration to surrounding air pollution.
Scientists trigger self-destruct switch in lung
cancer cells: (30
th
October, 2014)
Scientists have found a drug combination that can trigger the self-
destruct process in lung cancer cells - paving the way for new
treatments, according to research. "There's an urgent need to save
more lives from lung cancer and we hope these findings will one
day lead to effective new treatments to help lung cancer patients
and potentially those with other cancer types too," authors noted.
Heart's own immune cells can help it heal: (30
th

October, 2014)
The heart holds its own pool of immune cells capable of helping it
heal after injury, according to new research. In a mouse model of
heart failure, the researchers showed that blocking the bone
marrow's macrophages from entering the heart protects the
organ's beneficial pool of macrophages, allowing them to remain in
the heart, where they promote regeneration and recovery. The
findings may have implications for treating heart failure in
humans.
Genetic factors behind surviving or dying from
Ebola shown in mouse study: (30
th
October,
2014)
A newly developed mouse model suggests that genetic factors are
behind the mild-to-deadly range of responses to the Ebola virus.
The frequency of different manifestations of the disease across the
lines of these mice are similar in variety and proportion to the
spectrum of clinical disease observed in the 2014 West African
outbreak. The new mouse model might be useful in testing
candidate therapeutics and vaccines for Ebola, and in finding
genetic markers for susceptibility and resistance to the disease.
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High-intensity sound waves may aid regenerative
medicine: (30
th
October, 2014)
Researchers have developed a way to use sound to create cellular
scaffolding for tissue engineering, a unique approach that could
help overcome one of regenerative medicines significant obstacles.
Making lab-grown tissues stronger: (30
th

October, 2014)
Lab-grown tissues could one day provide new treatments for
injuries and damage to the joints, including articular cartilage,
tendons and ligaments. Cartilage, for example, is a hard material
that caps the ends of bones and allows joints to work smoothly.
Biomedical engineers are exploring ways to toughen up engineered
cartilage and keep natural tissues strong outside the body.
For detail mail to editor
KNOWLEDGE BASED ARTICLE
Encephalitis
Encephalitis is inflammation of the brain tissue. Most cases are
caused by viral infections. In rare cases it can also be caused by
bacteria.
There are two main types of encephalitisprimary and secondary.
Primary encephalitis is when a virus directly infects the brain and
spinal cord. Secondary encephalitis is when an infection that starts
elsewhere travels to brain.
This disease is rare. According to the Centers for Disease Control,
encephalitis occurs in one of every 2,000,000 people. Most people
who contract it are young children, individuals over 65, or those
with weak immune system.
Though rare, the disease is very serioussevere cases can cause
death.
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Causes:
The most common virus that causes encephalitis is herpes simplex.
Usually the herpes virus travels via a nerve to the skin. There it
causes a cold sore. In rare cases, the virus travels to the brain. This
form of encephalitis will often affect the temporal lobethe part of
the brain that controls memory and speech. It can also affect
the frontal lobewhich affects emotions and behavior. Herpes
encephalitis can cause severe damage.
Other common viruses that can cause encephalitis include:
mumps
Epstein-Barr virus
HIV
cytomegalovirus (CMV)
Childhood Viruses
The childhood viruses that used to commonly cause encephalitis
are now preventable by vaccines. Therefore, these types of
encephalitis are rare.
Some childhood viruses that can cause encephalitis include:
Chicken pox (very rare)
Measles. According to BBC health, measles causes encephalitis in
approximately one out of every 1,000 cases. In most cases, the
condition is mild. However 20 percent of those affected will have
long-term nerve damage. Up to 10 percent of cases are fatal.
Rubella. Approximately one in 5,000 rubella patients develop
encephalitis. It is fatal up to 20 percent of the time.
Arboviruses
Arboviruses are viruses carried by insects. The disease they cause
depends on the type of insect and what viruses they carry.
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California encephalitis is transmitted by mosquito bites. It is also
known as Lacrosse encephalitis. It mainly affects children. It has
few to no symptoms.
St. Louis encephalitis occurs in the rural Midwest and southern
states. It is generally mild. However, in people over 60, there is a 30
percent mortality rate.
West Nile is most often found in Africa and the Middle East.
However, it can occur in the US. West Nile is usually relatively
mild. It can be fatal among older individuals and those with
weakened immune systems.
Colorado encephalitis is also called Colorado tick fever. It is
transmitted by the female wood tick.
Eastern equine encephalitis is spread by mosquitoes. It affects both
humans and horses. It is often mild but it does have a two percent
mortality rate.
Kyasanur forest disease is transmitted by tick bites. It can also be
transmitted by drinking raw milk from goats, sheep, or cows. It
has a one to two percent mortality rate. People most at risk are
hunters, campers, forest workers, and farmers.
Risk Factors:
The groups most at risk of encephalitis are:
older individuals
children under 1 year of age
people with weakened immune systems.
Living in an area with high mosquito or tick populations also puts
you at risk. So does participating in outdoor activities when
insects are present.
Symptoms:
The symptoms of encephalitis can range from mild to severe. Each
type can have its own particular set of symptoms.
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Mild symptoms include:
fever
headache
neck stiffness
lethargy
general feeling of being unwell
headache will continue to get more severe
vomiting
Severe symptoms include:
very high fever
confusion
drowsiness
hallucinations
slower movements
coma
seizures
irritability
light sensitivity
unconsciousness
severe dementia
The symptoms in very young children are different.
vomiting
bulging fontanel (soft spot in the scalp)
non-stop crying
body stiffness
lack of appetite
Diagnosis:
If encephalitis is suspected, the following tests may be used:
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Spinal Tap Or Lumbar Puncture:
In this test, doctor will collect a sample of spinal fluid. The sample
is then tested for signs of infection
Brain Imaging With CT Scan Or MRI:
These tests detects changes in brain structure. They can rule out
other possible explanations for symptoms, such as a tumor
or stroke.
Electroencephalograph (EEG):
An EEG uses electrodes attached to the scalp to record brain
activity.
Blood Tests:
Blood testing can reveal signs of a viral infection.
Brain Biopsy:
In a biopsy, doctor will remove small samples of brain to test for
infection. This test is rarely performed. There is a high risk of side
effects. It is usually only used if doctors cannot tell what is causing
the brain swelling and treatments are not working.
Treatment:
Anti-viral medications are effective for treating herpes
encephalitis. However, they have not yet been shown to work for
other forms. Instead, treatment often focuses on relieving
symptoms, using:
pain killers
corticosteroids (to reduce brain inflammation)
mechanical ventilation, or breathing treatments
lukewarm sponge baths
anticonvulsants
sedatives (for seizures, restlessness, aggressiveness, and
irritability)
rest
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fluids (IV fluids are sometimes necessary)
Sometimes hospitalization is needed to deal with brain swelling
and seizures.
Jeenatara Begum
Assistant Professor
GNIPST
DISEASE RELATED BREAKING NEWS
Human infection with avian influenza A(H7N9)
virus China: (29
th
October, 2014)
On 19 October 2014, the National Health and Family Planning
Commission of China notified WHO of 2 additional laboratory-
confirmed cases of human infection with avian influenza A(H7N9)
virus, including 1 death.
Read more
UPCOMING EVENTS
5
th
International Conference on Stem Cells and Cancer 2014, JNU
Convention Centre, New Delhi, India from 8-10 November, 2014
DRUGS UPDATES
FDA Approves Xigduo XR (dapagliflozin and
metformin hydrochloride) for Type 2 Diabetes:
(30
th
October, 2014)
AstraZeneca announced that the U.S. Food and Drug
Administration has approved once-daily Xigduo XR (dapagliflozin
and metformin hydrochloride extended-release) for the treatment
of adults with type 2 diabetes.
Read more
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CAMPUS NEWS
Today the students of GNIPST have participated in the Run for
Unity as a mark of tribute to the efforts of the country's first
Home Minister Sardar Vallabhbhai Patel.
Congratulation to the winner of Cricket Tournament-B.Pharm 3rd
year, 2014
Runner up team-B.Sc and BHM, 2014
Congratulation to the highest run scorer of Cricket Tournament-
Tanmoy Das Biswas, B.Pharm 3rd year, 2014
Congratulation to the highest wicket taker of Cricket
Tournament-Subhodip Das, B.Pharm 3rd year, 2014
Congratulation to the winner of Carom Tournament (Boys)-
Sk. Abdul Salam, B.Pharm 2
nd
year, 2014
1st Runner up-Subhayan Dutta, M.Sc (Biotechnology Department)
2nd year, 2014
2nd Runner up-Nirupan Gupta, B.Pharm 1
st
year, 2014
Congratulation to the winner of Carom Tournament (Girls)-
Aishwarya Datta, B.Pharm 2
nd
year, 2014
1st Runner up-Krishnakali Basu, B.Pharm 3
rd
year, 2014
2nd Runner up-Rituparna Das, B.Pharm 3
rd
year, 2014
Congratulation to the winner of Chess Tournament (Boys)-
Basab Brata Dey, M.Sc (Biotechnology Department) 2
nd
year, 2014
1st Runner up-Ankit Chowdhury, B.Pharm 1
st
year, 2014
2nd Runner up-Smaranjeet Banik, B.Pharm 3
rd
year, 2014
Congratulation to the winner of Chess Tournament (Girls)-
Rituparna Das, B.Pharm 3
rd
year, 2014
1st Runner up-Varsa Srivastav, B.Sc(Bioptechnology Department)
1
st
year, 2014
2nd Runner up- Krishnakali Basu, B.Pharm 3
rd
year, 2014
The GNIPST Cricket Tournament, Carom Tournament and Chess
Tournament was held on 21
st
and 22
nd
October, 2014.
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The Cultural Programme on Bijoya Dashami and Kali Puja was
held on 20
th
October, 2014
An exhibition on Photography and Painting was held on 20
th

October, 2014
Congratulation to the winner of Football Tournament-B.Pharm
3rd year, 2014
Runner up team-B.Pharm final year, 2014
Congratulation to the winner of Table Tennis Tournament-
Krishnakali Basu, B.Pharm 3rd year, 2014
1st Runner up-Aindrila Bhowmick, B.Pharm 2nd year, 2014
2nd Runner up-Sayani Banerjee, B.Pharm 2nd year, 2014
The GNIPST Football Tournament (for male students) and Table
Tennis tournament (for female students) was held on 25th and
26th September, 2014.
On 5
th
September, 2014 the students of GNIPST have arranged a
wonderful Teachers Day Programme. On behalf of all the teachers
of GNIPST I would like to thank our beloved students.
The Freshers welcome programme was held on 14
th
August, 2014.
Welcome 1
st
year students.
We congratulate the following M.Pharm. final year students who
have made their positions in different pharmaceutical companies.
Anirban Banerjee (Emami Ltd.)
Mahender Roy (Stadmed private Ltd.)
We congratulate the following B.Pharm. final year students for
their success.
Samadrita Mukherjee (Abbott India Ltd.)
Suman Sarkar (Tata Medical Centre-Apollo Pharmacy)
Shrewashee Mukherjee (Fresenius Kabi-Parenteral Nutrition)
Avishek Naskar (Glaxo SmithKline-Marketing)
Bappaditya Manik (USV Limited)
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Sarbani Das (Nutri Synapzz-Marketing)
Ankita Roy (Nutri Synapzz-Marketing)
Rahul Mitra (B M Pharmaceuticals-Production)
The following B.Pharm. final year students have qualified, GPAT-
2014. We congratulate them all.
Utsha Sinha
Satarupa Bhattacharya
Sandipan Sarkar
Purbali Chakraborty
Reminiscence, 2014(GNIPST Reunion) was held in College
campus on 2
nd
February,2014.
1
st
Annual Sports of GNIPST was held on 3
rd
February,2014 in
College campus ground.
An industrial tour and biodiversity tour was conducted in Sikkim
for B.Pharm and B.Sc. students under the supervision of Mr. Asis
Bala, Ms. Jeentara Begum and Ms. Moumita Chowdhury.
B.Pharm 3
rd
year won the GNIPST Football Champions trophy,
2013. B.Pharm 3
rd
year won the final match 1-0 against B.Pharm 2
nd

year. Deep Chakraborty was the only scorer of the final.
STUDENTS SECTION
WHO CAN ANSWER FIRST????
Dr. S. K. Burman established which
pharmaceutical company?
Kavli prize is awarded in which
discipline?
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Answer of Previous Issues Questions:
A) Santosh Trophy
B) Football
Identify the person
Answer of Previous Issues Image:
Magnus Carlsen
Send your thoughts/
Quiz/Puzzles/games/write-ups or any other
contributions for Students Section&
answers of this Section at gnipstbulletin@gmail.com
EDITORS NOTE
It is a great pleasure for me to publish the 4
th
issue of 38
th
Volume
of GNIPST BULLETIN. All the followers of GNIPST BULLETIN
are able to avail the bulletin through facebook account GNIPST
bulletin I am very much thankful to all the GNIPST members and
readers who are giving their valuable comments, encouragements
and supports. I am also thankful to Dr. Abhijit Sengupta, Director
of GNIPST for his valuable advice and encouragement. Special
thanks to Dr. Prerona Saha, Mr. Debabrata Ghosh Dastidar
and Mr. Soumya Bhattacharya for their kind co-operation and
technical supports. Thank you Mr. Soumya Bhattacharya for the
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questionnaires of the student section. An important part of the
improvement of the bulletin is the contribution of the readers. You
are invited to send in your write ups, notes, critiques or any kind of
contribution for the forthcoming special and regular issue.
ARCHIVE
GNIPST organized a garment distribution programme on 28
th

September, 2013 at Dakshineswar Kali Temple and Adyapith,
Kolkata. On this remarkable event about hundred people have
received garments. More than hundred students and most of the
faculties participated on that day with lot of enthusiasm.
GNIPST celebrated World Heart Day (29
th
September) and
Pharmacists Day (25
th
September) on 25
th
and 26
th
September,
2013 in GNIPST Auditorium. A seminar on Violence against
woman and female foeticide was held on GNIPST Auditorium on
25
th
September organized by JABALA Action Research
Organization. On 26
th
September an intra-college Oral and Poster
presentation competition related to World Pharmacists day and
Heart day was held in GNIPST. Ms. Purbali Chakraborty of
B.Pharm 4
th
year won the first prize in Oral Presentation. The
winner of Poster presentation was the group of Ms. Utsa Sinha,
Mr. Koushik Saha and Mr. Niladri Banerjee (B.Pharm 4
th
year). A
good number of students have participated in both the
competition with their valuable views.
Teachers day was celebrated on 5
th
September, 2013 by the
students of GNIPST in GNIPST Auditorium.
Azalea (exotic flower ) , the fresher welcome programme for
newcomers of GNIPST in the session 2013-14 was held on 8
th

August in GNIPST Auditorium.
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One day seminar cum teachers development programme for
school teachers on the theme of Recent Trends of Life Sciences
in Higher Education organized by GNIPST held on 29
th
June,
2013 at GNIPST auditorium. The programme was inaugurated by
Prof . Asit Guha, Director of JIS Group, Mr. U.S. Mukherjee, Dy
Director of JIS Group and Dr. Abhijit Sengupta, Director cum
Principal of GNIPST with lamp lighting. The programme started
with an opening song performed by the B.Pharm students of this
institute. The seminar consists of a series of lectures, video
presentations and poster session. On the pre lunch session 4
lectures were given by Dr. Lopamudra Dutta, Mr. Debabrata
Ghosh Dastidar, Ms. Swati Nandy and Ms. Tamalika Chakraborty
respectively. On their presentation the speakers enlighten the
recent development of Pharmacy, Genetics and Microbiology and
their correlation with Life Sciences. On the post lunch session, Ms.
Saini Setua and Ms. Sanchari Bhattacharjee explained the recent
development and career opportunities in Biotechnology and
Hospital Management. The programme was concluded with
valedictory session and certificate distribution.
About 50 Higher secondary school teachers from different
schools of Kolkata and North& South 24 Parganas district of West
Bengal participated in this programme. A good interactive session
between participants and speakers was observed in the seminar.
The seminar was a great success with the effort of faculties, staffs
and students of our Institute. It was a unique discussion platform
for school teachers and professional of the emerging and newer
branches of Life Science.
The general body meeting of APTI, Bengal Branch has been
conducted at GNIPST on 15
th
June, 2012. The program started with
a nice presentation by Dr. Pulok Kr. Mukherjee, School of Natural
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31-10-2014
Products, JU on the skill to write a good manuscript for
publication in impact journals. It was followed by nearly two hour
long discussion among more than thirty participants on different
aspects of pharmacy education. Five nonmember participants
applied for membership on that very day.
GNIPST is now approved by AICTE and affiliated to WBUT for
conducting the two years post graduate course (M.Pharm)
in PHARMACOLOGY. The approved number of seat is 18.
The number of seats in B.Pharm. has been increased from 60 to
120.
AICTE has sanctioned a release of grant under Research
Promotion Scheme (RPS) during the financial year 2012-13to
GNIPST as per the details below:
a. Beneficiary Institution: Guru Nanak Institution of Pharmaceutical
Science & Technology.
b. Principal Investigator: Dr. LopamudraDutta.
c. Grant-in-aid sanctioned:Rs. 16,25000/- only
d. Approved duration: 3 years
e. Title of the project: Screening and identification of potential
medicinal plant of Purulia & Bankura districts of West Bengal
with respect to diseases such as diabetes, rheumatism, Jaundice,
hypertension and developing biotechnological tools for enhancing
bioactive molecules in these plants.
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