What question did the study ask?

Population/Problem

: Pregnant women that will undergo elective cesarean section

Intervention

: General Anesthesia

Comparison

: Spinal Anesthesia

Outcome

: APGAR Score

Are the results valid

1.A . Was the assignment of patients to
treatment randomized?
1. B. And was the randomization list
concealed?

2. Was follow-up of patients sufficiently long

and complete?

3. Were patients analyzed in the groups which

they were randomized?
4. Were patients and clinicians kept blind to
treatment?
5. Were the groups treated equally, apart from
the experimental treatment?

1.A. Yes, 60 healthy patients were split into 2

groups. 30 patients were given general
anesthesia and 30 others were given
spinal anesthesia. Randomization was
done restrictively so equilibrium can be
reached.
1.B. In this study, single or double blind
method are not mentioned.
No, the follow up of patients was only
conducted for 5 minutes after cesarean
delivery. But all of patients are completely
followed up.
Yes, every subject are analyzed in their own
group according to randomization. 30 subjects
in general anesthesia group, and 30 others in
spinal anesthesia group.
In this study, it is not mentioned if patients and
clinicians were kept blind to treatment.
Yes, although the anesthetic method are
different to each group, but every subject are
treated equally with elective cesarean section.
Yes, each group are the same since the
beginning of study.

6. Were the groups similar at the start of the

trial?
Are the valid result of this randomized
study important?
1. What is the magnitude of the treatment 1st Minute = CER: 66,7%; EER: 16,7%; RRR:
effect?
75%; ARR: 0,5; NNT: 2
5th Minute = CER: 100%; EER: 96,7%; RRR:
3%; ARR: 0,033; NNT: 30
2. How precise is this estimate of the It is not mentioned in this study about the
treatment effect?
confidence interval of the treatment effect.
Are these valid, important result applicable
to our patient?
1. Is our patient so different from those in the No, our patient has the same characteristics as
study that its results cannot apply?
the patients from the study.
2. Is the treatment feasible in our setting?
Yes, while considering effectivity and side
effects of treatment.
3. What are our patients potential benefits The benefit from the therapy is spinal
and harms from the therapy?
anesthesia is safer than general anesthesia. The
harm is APGAR Score in babies from patients
with general anesthesia are lower than ones in
spinal anesthesia.
4. What are our patients values and Yes, patients values and expectations are the

expectations for both the outcome we are spinal anesthesia are better than general
trying to prevent and the treatment we are anesthesia for the outcome which is the
offering?
APGAR Score from the babies.