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1. Describe the general functions of the nervous system. (sensory, integrative and motor)
a. Sg III A
b. Sensory receptors located at the ends of peripheral nerves are stimulated by changes in
the internal and external environment.
i. Examples of such stimuli are light, heat, and sound.
c. The resulting impulses travel to the central nervous system.
d. These impulses are then integrated or brought together so that they can be interpreted
as sensations, memories and perceptions.
e. Decisions about how to respond are made both consciously and unconsciously, motor
impulse travel to effector organs and a response to the sensory impulse is stimulated.
2. Describe the somatic and autonomic
a. Sg - III B
b. The somatic nervous system
i. under conscious control
ii. controls skeletal muscle.
c. Autonomic system
i. Effectors that are involuntary
ii. Eg. such as the heart, smooth muscle in blood vessels
3. Fill in the chart below comparing the supporting cells of the NS.
Neuroglial cells
Location
Function
Microglial cells
Scattered throughout
the central nervous
system.
Oligodendrocytes
Astrocytes
Ependymal cells
An epithelial like
membrane that covers
specialized brain parts
and forms the inner
lining that enclose
spaces within the brain
Peripheral nervous
system
Location
Function
Sensory or afferent
neurons
Interneurons or
association or
internuncial neurons
Motor neurons or
efferent neurons
7. Describe the events occurring in the cell membrane that permit conduction of an impulse.
a. The distribution of ions on either side of the cell membrane is subject to change and
that change is largely determined by sets of channels that cross the cell membrane.
Some channels are open all the time; others open and close in response to stimuli.
These channels may also be selective; that is they permit only one ion to pass through it.
As a general rule, potassium ions can pass through the cell membrane more easily than
sodium ions. Calcium ions are less able to cross the cell membrane than either sodium
or potassium. Thus sodium is primarily an extracellular ion while potassium is primarily
an intracellular ion. This difference is clearly evident when blood levels of electrolytes
are obtained. The normal level of potassium is 3.5.-5.0mEq/L; the level of sodium is
135-148mEq/L. This net loss of of potassium ions creates a slightly positive charge on
the outside of the cell membrane. This is called the cells resting potential.
b.
8. Describe membrane polarization, depolarization and repolarization. Which of these events is a
nerve impulse?
9.
a. Membrane polarization refers is the mildly positive charge of the outside of the cell
membrane relative to the interior of the cell membrane. Na and K pumps that require
energy to transport Na and K across the cell membrane against a concentration gradient
maintain polarization.
i. Depolarization occurs with a decrease in the resting potential. In other words,
when the inside of the cell membrane becomes less negative in relation to the
outside of the cell membrane.
ii. In order for depolarization to occur, there must be a stimulus of sufficient
strength to open the gated channels for both sodium and potassium.
iii. Repolarization occurs as the sodium ions diffuse inward, causing the outside of
the membrane to become negatively charged. This leads to opening of the
gated potassium channels, which rapidly restores the positive charge to the
outside of the membrane.
iv. A nerve impulse is created as depolarization creates a wave of action potentials
to move down the axon toward its end.
How do the Nodes of Ranvier affect nerve impulse conduction?
a. Nerves that are covered with myelin, most commonly peripheral nerves, can carry nerve
impulses more rapidly than non-myelinated fibers. This is due to interruptions in the
myelin sheath known as the Nodes of Ranvier. Instead of the need for an impulse to
travel the entire length of the nerve fiber as in non-myelinated fibers, impulses in
myelinated fibers can jump from one Node of Ranvier to another. This kind of impulse
conduction is called saltatory conduction.
10. Define the all-or-none response in neurons?
a. Nerves that carry impulses into the brain or spinal cord are sensory nerves.
21. What is a mixed nerve?
a. Nerves that include both sensory and motor fibers are mixed nerves.
22. What is a nerve pathway?
a. The routes that nerve impulses utilize as they travel through the nervous system are
nerve pathways.
b.
23. What is a reflex? A reflex arc?
a. A reflex is the simplest of nerve pathways. A reflex arc begins with a sensory receptor.
This moves to an interneuron within the central nervous system. These interneurons
serve as processing centers for reflex pathways. These two neurons form a reflex arc.
24. Be able to label the parts of a reflex in a drawing.
25. What are the bony coverings of the CNS?
a. The bony coverings of the central nervous system are the cranial cavity of the skull and
the spinal column.
26. Fill in the following chart of the meninges.
Layer
Location
Function
Dura mater
Outermost layer of
the meninges
Arachnoid mater
Thin web-like
membrane. Lacks
blood vessels
Subarachnoid space
contains the
cerebrospinal fluid.
Locations
Function
Motor
Movement of skeletal
muscles, speech, movements
of eyes and eye lids
Association
Parietal lobes
Vision
Temporal lobes
Hearing
34. What is the function of the dominant hemisphere? The non-dominant hemisphere?
a. The dominant hemisphere oversees the ability to use and understand language. In 90%
of the population, the left hemisphere is dominant for language related activities such
as speech, writing and reading and for complex intellectual function that requiring
verbal, analytical, and computational skills. The non-dominant hemisphere, usually the
right, is used for nonverbal functions such as motor tasks that require orientation of the
body in space, understanding and interpreting musical patterns, and nonverbal visual
experiences. This hemisphere also controls intuitive thinking and emotional thinking.
35. Describe the location of the ventricles
a. There are four ventricles; two lateral ventricles and 1 each third and
fourth ventricle. The lateral ventricles are located in the cerebral hemispheres and
extend into the frontal, temporal, and occipital lobes. The third ventricle is a narrow
space in the midline of the brain beneath the corpus callosum. The fourth ventricle is in
the brain stem just anterior to the cerebellum.
36. What is the function of cerebral spinal fluid? Where is it secreted?
a. Cerebrospinal fluid is secreted in a mass a specialized capillaries from the pia mater
known as the choroid plexuses. The brain and spinal cord float in this fluid which
supports and protects them by acting as shock absorbers. CSF also maintains electrolyte
balance in the central nervous system and serves as a pathway to the blood for
excretion of wastes.
2. Fill in the attached table Functions of the diencephalon
Structure
Location
Function
Thalamus
Hypothalamus
Maintains homeostasis by
regulating heart rate and rhythm,
temperature, water and
electrolyte balance, hunger and
body weight, movements and
glandular secretions of the GI
tract, production of
neurosecretory hormones that
stimulate production of pituitary
hormones, sleep and wakefulness.
37. What structures comprise the limbic system? What is the function of this system?
a. The limbic system is composed of nuclei (masses of gray matter) including the
hypothalamus, thalamus, and basal nuclei. The limbic system controls emotional
experience and expression. The limbic system recognizes threats to the organism and
produces emotions such as fear, anger, pleasure which guide the person to behaviors
that increase chances for survival.
38. Identify where the brain stem is and label its components.
a. The brain stem lies between the brain and the spinal cord and
connects these two structures. It is composed of the midbrain, pons, medulla oblongata
with its component centers that control vital functions, and the reticular formation.
39. Where is the midbrain located? What is its function?
a. The midbrain is located between the diencephalon and the pons. It contains bundles of
myelinated fibers that join the lower parts of the brain stem and spinal cord with the
higher parts of the brain. It includes part of the corticospinal tracts, the major
descending motor pathways. In terms of function, several visual reflexes are located in
the midbrain such as those that turn the eyes in concert with turning the head as well as
auditory reflex centers that turn the head in the direction of a sound.
40. Where is the pons located and what is its function?
a. The pons is a rounded bulge between the midbrain and the medulla oblongata. Nuclei
of the pons work with meduallary centers to regulate the rate and depth of breathing.
Other nuclei act as relay centers for impulses to the cerebellum and from the periphery
to higher brain centers.
41. Where in the medulla oblongata located? What vital activities does this structure provide?
a. The medulla oblongata extends from the pons to the foramen magnum of the skull.
The fourth ventricle is located in the medulla. Many corticospinal tracts cross over at
this level. The medulla is the control center for the heart, vasomotor dilatation and
contraction, respiratory rhythm and depth of breathing. In addition it is the center for
reflexes such as sneezing and coughing.
42. What are the parts of the PNS?
a. The parts of the peripheral nervous system are the somatic and
autonomic nervous systems.
Sensory
II Optic
Sensory
Vision
III Oculomotor
Motor
IV Trochlear
Motor
V.Trigeminal
Mixed
Motor
VII. Facial
Mixed
VIII.
Vestibulocochlear or
Auditory
Sensory
IX. Glossopharyngeal
Mixed
X. Vagus
Mixed
XI. Accessory
Motor
XII. Hypoglossal
Motor
a.
47. How are spinal nerves identified?
a. The spinal nerves are identified by numbers 1-31.
b. C1-C
48. What is the structure and function of the dorsal root? The ventral root?
a. The dorsal root contains the cell bodies of sensory neurons whose dendrites conduct
sensory impulses from the peripheral body parts. The ventral root or anterior or motor
root of each spinal nerve consists of axons from the motor neurons whose cell bodies
are located within the gray matter of the cord.
49. What is a plexus?
a. The main portions of the spinal nerves combine to form complex
networks call plexuses. In a plexus, spinal nerve fibers are sorted and recombined so
that fibers that innervate a particular body part reach it in the same nerve despite the
fact that the fibers may come from several different spinal nerves.
b.
50. Fill in the following table.
Plexus
Nerves involved
Structures innervated
Cervical plexus
Brachial plexus
Lumbosacral plexus
a. The pregangionic fibers of the sympathetic division originate from neurons in the gray
matter of the spinal cord. They leave the cord through the ventral roots of the spinal
nerves the first thoracic through the second lumbar segments. From the spinal cord
they enter a member of the chain of paravertebral ganglia. The preganglionic fibers of
the parasympathetic division arise from the brain stem and the sacral region of the
spinal cord.
55. Identify the neurotransmitters associated with pre and post ganglionic fibers in the sympathetic
and parasympathetic divisions.
a. The preganglionic fibers of both divisions of the autonomic nervous system secrete
acetylcholine as the neurotransmitter. They are cholinergic fibers. The parasympathetic
postganglionic fibers also use acetylchoine and are also cholinergic fibers. The
sympathetic postganglionic fibers secrete norepinephrine and are known as adrenergic
fibers. The different post-ganglionic neurotransmitters are responsible for the different
effects of the two divisions on effector organs.