UNIVERSITY MISSION

UNIVERSITY VISON

Republic of the Philippines

The Premier University in historic Cavite recognized

for excellence in the development of globally
competitive and morally upright individuals.

CAVITE STATE UNIVERSITY

(CvSU)
Don Severino Delas Alas Campus
Indang, Cavite

Cavite State University shall provide excellent, equitable and

relevant educational opportunities in the arts, science and
technology through quality instruction and relevant research
and development activities. It shall produce professional,
skilled and morally upright individuals for global
competitiveness.

DRUG STUDY
Name of Patient (Initial): O.T

Date of Admission: August 26, 2013

Age: 48 years old

Diagnosis: Typhoid Fever vs Leptospirosis

Sex: Male

Date Medication started:

DRUG

Generic Name:
Clonidine
Hydrochloride
Brand Name:
Catapres
Classification:
Antihypertensive
Central Analgesic
Symphatolytic
Dosage:
75 mg
Route:
Oral

MECHANISM OF
ACTION

INDICATION

CONTRAINDICATION

EFFECTS

Stimulates CNS
alpha2-adrenergic
receptors, inhibits
sympathetic
cardioaccelerator and
vasoconstrictor
centers and
decreases
sympathetic outflow
from the CNS.

-Hypertension, used
alone or as part of
combination therapy.

- Contraindicated
with hypersensitivity
to clonidine or any
adhesive layer
components of the
transdermal system.

CNS:
Drowsiness, sedation,
dizziness, headache,
fatigue, nightmares,
insominia,
hallucinations,
delirium,
nervousness,
restlessness, anxiety,
depression.

-Treatment of severe
pain in cancer
patientsin
combination with
opiates; epidural
more effective with
neuropathic pain.

-Use cautiously with

severe coronary
insufficiency, recent
MI, cerebrovascular
disease, chronic renal
failure; pregnancy,
lactation.

CV: Heart failure,

orthostatic
hypotension,
palpitations,
tachycardia,
bradycardia.

NURSINGR
RESPONSIBILITIES
Assessment
History:
Hypersensitivity to
clonidine or adhesive
layer components of
the transdermal
system; severe
coronary
insufficiency, recent
MI, CVD, chronic
renal failure,
lactation, pregnancy.
Physical:
Body weight, skin
color, lesions, mucous
membranes color,
breast examination,

Frequency:

Form:
Tablet
Color:

GU: Impotence,
sexual dysfunction,
nocturia, difficulty in
micturition, urinary
retention.
Dermatologic:
Rash, angioneurotic
edema, hives,
urticaria, alopecia,
pruritus, dryness,
itching, burning of
the eyes, pallor
GI:
Dry mouth,
constipation,
anorexia, malaise,
nausea, vomiting,
parotid pain,
parotitis, mild
transient
abnormalities in LFTs.
Others:
Weight gain,
transient
hyperglycemia, or
elevated serum
creatinine
phosphokinase level,
gynecomastia,
weakness, muscle or

orientation, affect,
reflexes,
ophthalmologic
examination,
perfusion, bowel
sounds, normal
urinary output.
Intervention:
-Do not discontinue
transdermal therapy
prior to surgery;
Monitor BP carefully
during surgery.
-Continue oral
clonidine therapy to
within 4 hr of surgery
then resume as soon
as possible
thereafter.

Submitted by: Flora Angeli D. Pastores

Year & Sec. Grp.: BSN 3-1 3
Date: August 29, 2013

joint pain, cramps of

the lower limbs,
dryness of the nasal
mucosa, fever.
Submitted to: Mr Rolando Antonio