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Professor, Department of Conservative Dentistry & Endodontics, SVS Institute of Dental Sciences, Mahaboob Nagar, Andhra Pradesh,
India; 2Senior Lecturer, Department of Conservative Dentistry & Endodontics, SVS Institute of Dental Sciences, Mahaboob Nagar, Andhra
Pradesh, India; 3Head & Professor, Department of Conservative Dentistry & Endodontics, Aditya Dental College, Beed, Maharashtra, India.
ABSTRACT
Ozone has been successfully used in medical field since many years owing to its oxidizing property making it an
excellent antimicrobial agent. Moreover its potent anti-inflammatory property along with favorable cellular and
humoral immune response made ozone an effective therapeutic agent. Also its ability to arrest and reverse carious
lesions in a predictable way opened up a new chapter in minimal intervention dentistry. Furthermore its efficacy in
curbing resistant poly microbial root canal flora appears very promising. This article is based on information
through valid textbooks, peer reviews, journals and medline/pubmed search.
Key Words: Ozone, Endodontics, Minimal Intervention Dentistry.
How to cite this article: Reddy S A, Reddy N, Dinapadu S, Reddy M, Pasari S. Role of Ozone Therapy in Minimal
Intervention Dentistry and Endodontics - A Review. J Int Oral Health 2013; 5(3):102-108.
Source of Support: Nil
rd
Address for Correspondence: Dr. Shilpa Reddy A. Associate Professor, Department of Conservative Dentistry &
Endodontics, SVS Institute of Dental Sciences, Mahaboob Nagar, Andhra Pradesh, India.
Email: shilpareddyadmala@gmail.com. Phone: +91 (0) 9399943444.
Introduction
History
future
in
minimal
intervention
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Journal.
thus
wound healing.
reducing
inflammation
and
promoting
Effect on Micro-circulation:
USA.
increases
of Ozone in Medicine.
their
contact
area
for
oxygen
resistant
strains
with
accelerated
transcriptase
thus
hampering
viral
protein
synthesis.
Fungal & Protozoa: Ozone inhibits cell growth at
certain stages.
reactivates
the
immune
system
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HealOzone
Applications:
(Curozone,
USA).
Prozone (W&H)
for
disinfection
and
sterilization.
antimicrobial
sterilization
of hemorrhage.
whereas
A.naeslundii
9,10
effect
from
disinfection
to
60sec
in
exposure
carious
almost
lesions
eliminated
in
roots11,12.
metabolic
improved
induced
bactericidal
ozonated
biofilm.
water
increased
lipopolysaccharide
activity
against
plaque
followed by a restoration.
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Caries Severity
Diagnodent
Clinical
Index
Reading
diagnosis
<10
10-16
20-24
Radiographic
interpretation
Treatment plan
10 Sec O3/Seal Fissures if
May be a
Normal
sound tooth
Normal (lesion
White spot
not seen on x-
lesions
rays)
on x-rays
40 sec O3 and
remineralisation therapy
Air abrasion and/or seal
fissures
Air abrasion/etch/40 sec O3
therapy and restoration with
GIC/composite
Remove infected dentin, leave
Caries
4
25-29
May/may not
involving
be visible on X-
1-2mm
rays
of dentin
Caries
5
>30
involving
Mostly visible
on X-Rays
depending on remaining
>2mm of dentin
Deep carious
6
>99
lesion,
may/may not
involve pulp.
pulp vitality
remineralisation is evident, it
can be restored with a
permanent restoration.
Recommended ozone concentration (O3): 3.5-5 g/ml& flow Rate: 0.5-1 L/min.
ozone is found to instantly reduce pain in these
sensitive teeth8.
trauma
hyper
from
occlusion
may
cause
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terminating sensitivity.
anti-microbial
efficacy
was
comparable
to
Root
Canal
biomechanical
Therapy:
preparation,
After
effective
irrigation
with
with
radiological,
and
bacteriological
studies
are
demonstrated
bacterial
organized
in
biofilm19.
Ozone
action
against
anti-microbial
strains
such
as
mycobacteria,
in
randomized
control
trials.
Ozone
epiphora,
rhinitis,
cough,
upper respiratory
nausea,
vomiting,
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N-acetyl cysteine.
Staphylococcus
aureus.
Braz
Dent
J.
2006;17(2):134-8.
Contraindications:-
1. Pregnancy
ozone.
Appl
Environ
Microbiol.
1981;41(3):718-23.
deficiency
3. Hyperthyroidism
4. Severe anemia
5. Severe Myasthenia
ozonated
Inflamm. 1999;8(4-5):205-9.
human
platelets.
Mediators
9. Ozone allergy
Conclusion:
http://www.medozons.com
9. Baysan A, Beighton D. Assessment of the
ozone-mediated killing of bacteria in infected
further
research
is
required
to
References:
2. http://www.absoluteozone.com/ozone_article
ozone
_dentistry.htm
K,
on
enamel
physical
treatment
Shinriki
N.
Ozonolysis
of
mechanical
properties
of
dental
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Oral
Pathol
Oral
2008;24(10):1428-34.
2008;105(3):e85-91.
Radiol
Endod.
Sci. 2006;114(4):349-53.
dental
unit
waterlines.
Periodontol.
2003;74(11):1595-609.
24. Wikipedia-
http://en.w.k.pedia.org./wiki/ozone-
2007;18(4):299-304.
Rev.2004;(3):CD004153.
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