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Chapter 1

PHARMACY HISTORY

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Simple Choice
Select the correct answer by marking the appropriate capital letter. There is only one correct
answer.
1. Who was the god of medicine and healing in ancient Greece?
A) Zeus
B) Asclepios
C) Hermes
D) Dioscorides
E) Artemis
2. Who introduced the principle of primum nil nocere?
A) Hygieia
B) Apollo
C) Plinius
D) Panacea
E) Hippocrates
3. Whose name is linked to the following definition?
"Everything is poison, there is poison in everything. Only the dose makes a thing not a poison."
A) Galen
B) Ehrlich
C) Paracelsus
D) Avicenna
E) Dioscorides
4. Whose name is linked to Contraria contrairis principle?
A) Asclepios
B) Avicenna
C) Dioskorides
D) Galen
E) Plinius
5. Which is considered the main work of Avicenna?
A) India Herbs
B) Materia Medica
C) Canon Medicinae
D) Extracts and tinctures
E) Etymology
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6. Who is the patron saint of pharmacists in Europe ?


A) St. Christopher
B ) St. Anthony
C) St. Teresa
D) St. Cosma
E) St. Damian
7. In which city was the first European pharmacy set up?
A) Rome
B) Brussels
C) Naples
D) Paris
E) London
8. Who discovered DNA?
A) Gregor Mendel
B) James D. Watson and Francis Crick
C) Friedrich Miescher
D) Frederick Banting and Charles Best
E) Charles Darwin
9. Which is the oldest known medical text?
A) Rosetta stone
B) Kahun Papyrus
C) Berlin Papyrus
D) Novae Constitutiones
E) Generale Normativum in Re Sanitatis
10. What is the first surviving written record of Hungarian pharmacy?
A) De medicina
B) Medicina pauperum
C) Pray-codex
D) Vademecum Hungaria
E) Norma Pauperum
11. Which of the following concepst is linked to the name of Paracelsus?
A) Quinta essentia
B) Emplastrum
C) Materia medica
D) Decoctum,

E) Sympatheia
12. When were the medical and the pharmaceutical professions separated in Europe?
A) 11th century
B) 12th century
C) 13th century
D) 14th century
E) 15th century
13. Which was the earliest law governs the pharmacy practice at in Hungary?
A) Taxa Pharmaceutica Posoniensis
B) Materiae Medicae
C) Generale Normativum in Re Sanitatis
D) Buda Law-Book
E) Taxa Medicamentorum
14. Who first isolatied morphine?
A) Staudinger
B) Bernoulli
C) Sertrner
D) Harvey
E) Galvani
15. Which topic is associated with the name of the Hungarian-born Kroly Ereky?
A) Nanotechnology
B) Bioinformatics
C) Chronotherapy
D) Biotechnology
E) Pulse system
16. Where and when was the first known pharmacy opened?
A)
B)
C)
D)
E)

Ancient Greece, in BC 152


Rome, in BC 60
Alexandria, in 46
Baghdad, in 754
North America, in 1492

17. Who developed the first synthesis of urea?


A) Kolbe
B) Whler
C) Ostwald
D) Schleiden
E) Lindt

18. Who developed the first ultramicroscope?


A) Than
B) Proust
C) Kolbe
D) Zsigmondy
E) Winkler
19. Who first introduced intravenous injections for medicinal purposes?
A) Wren
B) Wood
C) Major
D) Pasteur
E) Linn
20. Which of the following statements about Galen?
A) the applied different drugs with well-defined composition and quality
B) the successfully applied iatrochemistry
C) the introduced specific prescriptions
D) the also dealt with alchemy
E) He was born in BC 131
21. Who introduced soft gelatin capsules?
A) Murdock and Wren
B) Murdock and Mothes
C) Mothes and Dublanc
D) Murdock and Scherer
E) Scherer and Mothes
22. Whose name is linked to nanotechnology?
A) Winkle
B) Feynman
C) Scheele
D) Wren
E) Dost
23. Who invented the tableting machine?
A) Kilian
B) Fette
C) Brockedom
D) Engler
E) Manesty

24. Which the terms was used first by Dost?


A) Pharmacodinamy
B) Chronotherapy
C) Pharmacokinetics
D) Pharmakology
E) Biotechnology
25.Who discovered the liposomes?
A) Sumio
B) Bangham
C) Kroto
D) Curl
E) Papahadjopoulos

1/2.
Multiple Choice
The following questions have one or more correct answers. Use the notations given below:
A: only the 1st , 2nd and 3th are correct
B: only the 1st and 3th are correct
C: only the 2nd and 4th answers are correct
D: only the 4th answers is correct
E: all of the answers are correct
26. Which of the following statements to Asclepios are correct?
1) He was the son of Apollo
2) He was the son of Artemis
3) A special procedures used in the island of Kos was the "incubation ", i.e. the application of

recovery sleep
4) According to tradition, he had two children, who also also achieved great results in medical

27. Which of the following statements relating to Avicenna are not correct?
1) He was born ca. 580
2) He was born ca. 980
3) His book was a standard medical text in Europe and the Islamic world up until the 16th
century
4) His book was a standard medical text in Europe and the Islamic world up until the 18th
century
28. Which of the following statements relating to Dioscorides?
1)
2)
3)
4)

He was the author of first detailed European encyclopedia on herbal medicine


He was a surgeon with the army of the emperor Nero
His main work, "De materia medica ", was a precursor to all modern pharmacopeias
He was known as father of botany

29. Which of the following statements relating to Theophrastos?


1) His surviving botanical works were had an important influence on medieval science
2) He studied in the school of Plato
3) He was the father of botany
4) He discovered photosynthesis

30. Which of the following statement relating to Albert Szent-Gyorgyi?


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1) He won the Nobel Prize in Physiology


2) He won the Nobel Prize in Chemisrty
3) He discovered vitamin C and the components of the citric acid cycle
4) He discovered the citric acid and synthesis of vitamin C
31. Which of the following statements relating to Karoly Nikolics?
1) He was the president of International Association of Pharmacy History
2) He received Lifetime Achievement Award in the FIP Congress in Lisbon in 1994
3) He was President of the FIP
4) He was head of a pharmacy, in Sopron (Hungary)
32. Which of the following statements relating to Lajos Winkler?
1) He discovered the citric acid
2) He discovered vitamin B
3) He discovered vitamin C
4) He was the founder of the Hungarian pharmaceutical chemistry
33. Which of the following statements relating to Matyas Rozsnyay?
1)
2)
3)
4)

He discovered the Chininum tannicum


His doctoral thesis dealt with the determination of dissolved oxygen in water
He established a public foundation to support the scientific work of young pharmacists
He constructed refractometer

34. Which of the following statements relating to Paul Ehrlich?


1) He suggested the possibility of selective therapy
2) He was a pioneer of modern chemotherapy and immunology
3) He dreamed of the "magic pill"
4) He discovered of Prontosil rubrum
35. Which of the following statements relating to Alexander Fleming?
1)He was a Scottish bacteriologist
2) He studied the effect of penicillin in experimental animals
3) He first vaccinated people against typhoid
4) He produced a purified form of penicillin
36. Which of the following statements relating to aspirin?
1) Its chemical structure was discovered by Edward Stone,in 1859
2) It was patented in 1899
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3) In combination with warfarin, it decreases the risk of gastrointestinal bleeding


4) A chemically pure and stable form was produced by Felix Hoffmann
37. Which of the following statements relating to Endre Kazay?
1) senior was the " Pharamacy" journal
2) born in Vrtesacsa
3) a manager was in the Galen pharmaceutical factory in Budapest
4) constructed refractometer and polarimeter
38. Which statement apply to Gedeon Richter?
1) He was born in 1920
2) His company produced organotherapeutic drugs
3) He exracted adrenaline from cortex of suprarenal glands
4) He founded a pharmaceutical works in Hungary before the outbreak of the First World War
39. Which of the following was a famous pharmacist?
1) Friedrich Sertrner
2 Henrik Ibsen
3) Dante Alighieri
4) Isaac Newton

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Association
40. Pair the individuals and their activities.
A) He developed a method to extract morphine
B) He was among the first to examine the toxicological effects of drugs
C) He was the founder of modern drug control
D) His doctoral thesis dealt with the determination of dissolved oxygen
E) He was associated with the production of Chininum tannicum
1) Elemr Schulek
2) Sndor Mozsonyi
3) Lajos Winkler
4) Jnos Kabay
41. Pair the individuals and their activities.
A) Abu al-Qasim al-Zahrawi (Abulcasis)
B) Muhammad ibn Zakarya Rzi (Rhazes)
C) Hamurappi
D) Asclepiades
E) Avicenna
1) He provided punishment for unsuccessful healing
2) He promoted application of chemical compounds in medicines
3) He pioneered the preparation of medicines by sublimation and distillation
4) He was the founder of the Roman medicine

42. Pair the individuals and their activities.


A) Michael Faraday
B) Friedrich Whler
C) Adolf Wilhelm Hermann Kolbe
D) Mattias Jacob Schleiden
E) Antoine Becquerel
1) He disproved the theory of vis vitalis
2) He discovered electromagnetic induction
3) He discovered nuclear radiation
4) He discovered a synthesis of salicylic acid
43. Pair the individuals and their activities.
A) Claudius Galenus

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B) Paracelsus
C) Imhotep
D) Louis Pasteur
E) Theodor Jacob Schleiden
1) He pioneered the use of chemicals and minerals in medicine
2) He developed an anthrax vaccine
3 ) He wrote texts on ancient Egyptian medicine describing diagnosis and treatment
4) He was a physician of Emperor Marcus Aurelius

44. Pair the individuals and the alkaloids that they first isolated
A) Joseph Pelletier
B) Friedrich Sertrner
C) Georg Franz Merck
D) Sune Bergstrm
E) Pierre Jean Robiquet
F) Friedrich Ferdinand Runge
1) Atropine
2) Morphine
3) Codeine
4) Papaverine
5) Quinine
45. Pair the following antibiotics and their discoverers.
A) streptomycin
B) salvarsan
C) prontosil
D) cephalosporin
E) penicillin
1) Selman Waksman
2) Paul Ehrlich
3) Giuseppe Brotzu
4) Gerhard Domagk
46. Pair the individuals and their discoveries.
A) Theodor Jacob Schleiden
B) Robert Koch
C) Claude Bernard
D) Willian Harvey
E) William Withering
1) The circulation of the blood
2) The agent of tuberculosis and cholera
3) The mechanism of action of curare
4) The cell theory

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47. Pair the inventors and their discoveries.


A) Soft gelatin capsules
B) Liposomes
C) Automated capsule manufacturing
D) Fullerene
E) The structure of DNA
1) Alec D. Bangham
2) Harold Kroto
3) Jozeph Dunblanc
4) Robert Pauli Scherer
48. Pair the individuals and their activities.
A) He discovered vitamin D
B) He discovered that childbed fever was caused by doctors transferring
C) He developed a rabies vaccine
D) He developed vaccine against the poliomyelitis
E) He discovered Oral Polio Vaccine
1) Ignac Semmelweis
2) Edward Mellanby
3) Louis Pasteur
4) Jonas Salk

49. Pair the names and their concepts.


A) Torsten Teorell
B) Gordon L. Amidon
C) Gerhard Levy
D) Friedrich Hartmut Dost
E) Paul Ehrlich
1) Pharmacokinetics
2) Biopharmaceutical Classification System (BCS)
3) Biopharmacy
4) Receptor theory
50. Pair the individuals and their discoveries.
A) Pasteur
B) Gyrgy Bksy
C) Jenner
D) Zoltn Vmossy
E) van Leeuwenhoek

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1) The microscope
2) Rabies vaccine
3) Smallpox vaccine
4) The laxative effect of phenolphthalein

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Answer key
1. Simple Choice

1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
24.
25.

B
E
C
D
C
E
C
C
B
C
A
C
D
C
D
D
B
D
A
A
C
B
C
C
B

2. Multiple Choice
26.
27.
28.
29.
30.
31.
32.
33.
34.
35.
36.
37.
38.
39.

C
B
A
A
C
A
C
D
B
A
B
C
C
E

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3. Association
40. 1-C
40. 2-B
40. 3-D
40. 4-A
41. 1-C
41. 2-B
41. 3-A
41. 4-D
42. 1-B
42. 2-A
42. 3-E
42. 4-C
43. 1-B
43. 2-D
43. 3-C
43. 4-A
44. 1-F
44. 2-B
44. 3-E
44. 4-C
44. 5-A
45. 1-A
45. 2-B
45. 3-D
45. 4-C
46. 1-D
46. 2-B
46. 3-C
46. 4-A
47. 1-B
47. 2-D
47. 3-A
47. 4-C
48. 1-B
48. 2-A
48. 3-C
48. 4-D

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49. 1-D
49. 2- B
49. 3-C
49. 4-E
50. 1-E
50. 2-A
50. 3-C
50. 4-D

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