Sie sind auf Seite 1von 16

Race and genetics

From Wikipedia, the free encyclopedia

The relationship between race and genetics is relevant to the controversy concerning race. In everyday life
many societies classify populations into groups based on phenotypical traits and impressions of probable
geographic ancestry and socio-economic status - these are the groups we tend to call "races". Because the
patterns of variation of human genetic traits are clinal, with a gradual change in trait frequency between
population clusters, it is possible to statistically correlate clusters of physical traits with individual geographic
ancestry. The frequencies of alleles tend to form clusters where populations live closely together and interact
over periods of time. This is due to endogamy within kin groups and lineages or national, cultural or linguistic
boundaries. This causes genetic clusters to correlate statistically with population groups when a number of alleles
are evaluated. Different clines align around the different centers, resulting in more complex variations than those
observed comparing continental groups.
For example if a person has light skin, light hair and blue eyes, a combination of traits that seems to have
evolved in Northern Europe and is found at a high frequency there, it is probable that person has some recent
European ancestry. And by extension, according to the racial categories in use in North America that person is
likely to be classified by others, and to self-identify, as "white". In a similar way, Genetic analysis enables us to
determine the geographic ancestry of a person pinpointing the migrational history of a person's ancestors with a
high degree of accuracy, and by inference the probable racial category into which they will be classified in a
given society. In that way there is a distinct statistical correlation between gene frequencies and racial categories.
However, because all populations are genetically diverse, and because there is a complex relation between
ancestry, genetic makeup and phenotype, and because racial categories are based on subjective evaluations of
the traits, it is not the case that there are any specific genes, that can be used to determine a person's race.
Research in genetics offers a means to classify humans which is more precise than broad phenotypically based
racial categories, given that genetics can provide a much more complex analysis of individual genetic makeup
and geographic ancestry, than self identified membership of a racial category. With a blood transfusion, for
example, it is vital to know the genetically determined blood type of the donor and recipient, but it is not helpful
to know their respective geographic ancestries. Most physical anthropologists consider race to be primarily a
social category that does not correspond significantly with biological variation, but some anthropologists,
particularly forensic anthropologists, consider race a useful biological category. They argue that it is possible to
determine race from physical remains with a reasonable degree of certainty; what is identified is the geographic
phenotype. Medical practitioners also sometimes argue that racial categories can be used successfully as proxies
to assess risk of those different heritable illnesses that occur with different frequencies among populations of
different geographic ancestries. Others argue that this use may be problematic because it risks underestimating
risks of individuals from ethno-racial categories that are not considered high-risk, and to overestimate the risk in
populations that are, resulting in stigmatization.

Contents
1 Genetic variation
2 Research methods
2.1 Trait, protein and gene studies
2.2 Population genetics
2.2.1 Structure
2.2.2 Distance
Print to PDF without this message by purchasing novaPDF (http://www.novapdf.com/)

2.3 History and geography


2.4 Validation
3 Ancestral populations
4 Population structures
4.1 Group size
4.2 Between-group genetics
4.3 Self-identification
4.4 Genetic-distance increase
4.5 Number of clusters
4.6 Utility
5 Race and medicine
6 See also
7 References
8 Further reading

Genetic variation
Genetic variation arises from mutations, migration between populations (gene flow) and from the reshuffling of
genes through sexual reproduction. Variation is counteracted by natural selection and genetic drift for example
founder effect, when a population is founded small number of initial founders and hence has a correspondigly
small degree of genetic variation. Epigenetic inheritance are heritable changes in phenotype (appearance) or
gene expression caused by mechanisms other than changes in the DNA sequence.
Human phenotypes are highly polygenic (dependent on interaction by many genes) and are influenced by
environment as well as genetics.
Nucleotide diversity is based on single mutations, single nucleotide polymorphisms (SNPs). The nucleotide
diversity between humans is about 0.1 percent (one difference per one thousand nucleotides between two
humans chosen at random). This amounts to approximately three million SNPs (since the human genome has
about three billion nucleotides). There are an estimated ten million SNPs in the human population.
Research has shown that non-SNP (structural) variation accounts for more human genetic variation than single
nucleotide diversity. Structural variation includes copy-number variation and results from deletions, inversions,
insertions and duplications. It is estimated that approximately 0.4 percent of the genomes of unrelated people
differ, apart from copy number. When copy-number variation is included, human-to-human genetic variation is
estimated to be at least 0.5 percent.

Research methods
Trait, protein and gene studies
Early classification attempts measured surface traits.

Print to PDF without this message by purchasing novaPDF (http://www.novapdf.com/)

Before the discovery of DNA, scientists used blood proteins (the human blood group systems) to study human
genetic variation. Research by Ludwik and Hanka Herschfeld during World War I found that the incidence of
blood groups A and B differed by region; for example,
among Europeans 15 percent were group B and 40
percent group A. Eastern Europeans and Russians had a
higher incidence of group B; people from India had the
greatest incidence. The Herschfelds concluded that
humans comprised two "biochemical races", originating
separately. It was hypothesized that these two races
later mixed, resulting in the patterns of groups A and B.
This was one of the first theories of racial differences to
include the idea that human variation did not correlate
Geographic distribution of blood group A
with genetic variation. It was expected that groups with
similar proportions of blood groups would be more
closely related, but instead it was often found that
groups separated by great distances (such as those from
Madagascar and Russia), had similar incidences.[1]
Researchers currently use genetic testing, which may
involve hundreds (or thousands) of genetic markers or
the entire genome.

Population genetics
Structure
Several methods to examine and quantify genetic
subgroups exist, including cluster and principal
components analysis. Genetic markers from individuals
are examined to find a population's genetic structure.
While subgroups overlap when examining variants of
one marker only, when a number of markers are
examined different subgroups have different average
genetic structure. An individual may be described as
belonging to several subgroups. These subgroups may
be more or less distinct, depending on how much
overlap there is with other subgroups. One such
mathematical method is.. The population genetic
structure found is often similar.[3][4][5]

Geographic distribution of blood group B

World map based on genetic principal component


analysis of human populations from Luigi Luca
Cavalli-Sforza's 1994 History and Geography of
Human Genes.[2]

In cluster analysis, the number of clusters to search for K


is determined in advance; how distinct the clusters are varies. The results obtained from cluster analyses depend
on several factors:
A large number genetic markers studied facilitates finding distinct clusters.[6]
Some genetic markers vary more than others, so fewer are required to find distinct clusters.[7] Ancestryinformative markers exhibits substantially different frequencies between populations from different
geographical regions. Using AIMs, scientists can determine a person's ancestral continent of origin based
solely on their DNA. AIMs can also be used to determine someone's admixture proportions.[8]

Print to PDF without this message by purchasing novaPDF (http://www.novapdf.com/)

The more individuals studied, the easier it becomes to detect distinct clusters (statistical noise is
reduced).[7]
Low genetic variation makes it more difficult to find distinct clusters.[7] Greater geographic distance
generally increases genetic variation, making identifying clusters easier.[9]
A similar cluster structure is seen with different genetic markers when the number of genetic markers
included is sufficiently large. The clustering structure obtained with different statistical techniques is similar.
A similar cluster structure is found in the original sample with a subsample of the original sample.[10]
Distance
Genetic distance is genetic divergence between species or populations of a species. It may compare the genetic
similarity of related species, such as humans and chimpanzees. Within a species, genetic distance measures
divergence between subgroups.
Genetic distance significantly correlates to geographic distance between populations, a phenomenon sometimes
known as "isolation by distance".[11] Genetic distance may be the result of physical boundaries restricting gene
flow such as islands, deserts, mountains or forests.
Genetic distance is measured by the fixation index (FST). FST is the correlation of randomly chosen alleles in a
subgroup to a larger population. It is often expressed as a proportion of genetic diversity. This comparison of
genetic variability within (and between) populations is used in population genetics. The values range from 0 to 1;
zero indicates the two populations are freely interbreeding, and one would indicate that two populations are
separate.

History and geography


Cavalli-Sforza has described two methods of ancestry analysis.[12] Current-population genetic structure does
not imply that differing clusters or components indicate only one ancestral home per group; for example, a
genetic cluster in the US comprises Hispanics with European, Native American and African ancestry.[6]
Geographic analyses attempt to identify places of origin, their relative importance and possible causes of genetic
variation in an area. The results can be presented as maps showing genetic variation. Cavalli-Sforza and
colleagues argue that if genetic variations are investigated, they often correspond to population migrations due to
new sources of food, improved transportation or shifts in political power. For example, in Europe the most
significant direction of genetic variation corresponds to the spread of agriculture from the Middle East to Europe
between 10,000 and 6,000 years ago.[12] Such geographic analysis works best in the absence of recent largescale, rapid migrations.
Historic analyses use differences in genetic variation (measured by genetic distance) as a molecular clock
indicating the evolutionary relation of species or groups, and can be used to create evolutionary trees
reconstructing population separations.[12]

Validation
Results of genetic-ancestry research are supported if they agree with research results from other fields, such as
linguistics or archeology.[12] Cavalli-Sforza and colleagues have argued that there is a correspondence between
language families found in linguistic research and the population tree they found in their 1994 study. There are
Print to PDF without this message by purchasing novaPDF (http://www.novapdf.com/)

generally shorter genetic distances between populations using languages from the same language family.
Exceptions to this rule are Sami, Tibetans and Ethiopians, who are genetically associated with populations
speaking languages from other language families. The Sami speak a Uralic language, but are genetically primarily
European. This is argued to have resulted from migration (and interbreeding) with Europeans while retaining their
original language. Agreement also exists between research dates in archeology and those calculated using
genetic distance.[7][12]

Ancestral populations
A 1994 study by Cavalli-Sforza and colleagues evaluated genetic distances among 42 native populations based
on 120 blood polymorphisms. The populations were grouped into nine clusters: African (sub-Saharan),
Caucasoid (European), Caucasoid (extra-European), northern Mongoloid (excluding Arctic populations),
northeast Asian Arctic, southern Mongoloid (mainland and insular Southeast Asia), Pacific islander, New
Guinean and Australian, and American (Amerindian). Although the clusters demonstrate varying degrees of
homogeneity, the nine-cluster model represents a majority (80 out of 120) of single-trait trees and is useful in
demonstrating the historic phylogenetic relationship among these populations.[13]
The greatest genetic distance between two continents is between Africa and Oceania, at 0.2470. Based on
physical appearance this is counterintuitive, since indigenous Australians and New Guineans resemble Africans
(with dark skin and curly hair). This measure of genetic distance reflects the isolation of Australia and New
Guinea since the end of the last glacial maximum, when the continent was isolated from mainland Asia due to
rising sea levels. The next-largest genetic distance is between Africa and the Americas, at 0.2260. This is
expected, since the longest geographic distance by land is between Africa and South America. The shortest
genetic distance, 0.0155, is between European and extra-European Caucasoids. Africa is the most genetically
divergent continent, with all other groups more related to each other than to sub-Saharan Africans. This is
expected, according to the single-origin hypothesis. Europe has a general genetic variation about three times less
than that of other continents; the genetic contribution of Asia and Africa to Europe is thought to be two-thirds
and one-third, respectively.[12][13]
Recent studies have been published using an increasing number of genetic markers.[7][10][14][15][16][17][18][19]
Research has also been done on smaller regions (for example, the genetic history of Europe, the genetic history
of Italy and genetic studies on Jews).

Population structures
Definitions of race are rooted in taxonomic classifications first developed in 18th- and 19th-century Europe.
Race has overlapped with a debate about species known as the species problem.
Since the 1960s scientists have understood race as a social construct imposed on phenotypes in culturally
determined ways, rather than a biological concept. A 2000 study by Celera Genomics found that human DNA
does not differ significantly across populations. Citizens of any village in the world, in Scotland or Tanzania, have
90 percent of the genetic variability humanity has to offer. Only .01 percent of genes account for a person's
appearance.[20] Biological adaptation plays a role in bodily features and skin type. According to Luigi Luca
Cavalli-Sforza, "From a scientific point of view, the concept of race has failed to obtain any consensus; none is
likely, given the gradual variation in existence. It may be objected that the racial stereotypes have a consistency
that allows even the layman to classify individuals. However, the major stereotypes, all based on skin color, hair
color and form, and facial traits, reflect superficial differences that are not confirmed by deeper analysis with
more reliable genetic traits and whose origin dates from recent evolution mostly under the effect of climate and
perhaps sexual selection".[2][21] [22] [23] [24] [24][25] [26]
Print to PDF without this message by purchasing novaPDF (http://www.novapdf.com/)

Group size
Research techniques can be used to detect genetic population differences if enough genetic markers are used;
the Japanese and Chinese East Asian populations have been identified.[27] Sub-Saharan Africans have greater
genetic diversity than other populations.[28]

Between-group genetics
In 1972, Richard Lewontin performed a FST statistical analysis using 17 markers (including blood-group
proteins). He found that the majority of genetic differences between humans (85.4 percent) were found within a
population, 8.3 percent were found between populations within a race and 6.3 percent were found to
differentiate races (Caucasian, African, Mongoloid, South Asian Aborigines, Amerinds, Oceanians, and
Australian Aborigines in his study). Since then, other analyses have found FST values of 610 percent between
continental human groups, 515 percent between different populations on the same continent and 7585
percent within populations.[29][30][31][32][33]
While acknowledging Lewontin's observation that humans are genetically homogeneous, A. W. F. Edwards in
his 2003 paper "Human Genetic Diversity: Lewontin's Fallacy" argued that information distinguishing populations
from each other is hidden in the correlation structure of allele frequencies, making it possible to classify
individuals using mathematical techniques. Edwards argued that even if the probability of misclassifying an
individual based on a single genetic marker is as high as 30 percent (as Lewontin reported in 1972), the
misclassification probability nears zero if enough genetic markers are studied simultaneously. Edwards saw
Lewontin's argument as based on a political stance, denying biological differences to argue for social equality.[4]
In The Ancestor's Tale Richard Dawkins devotes a chapter to the subject of race and genetics. After an
extensive discussion race, and how the term is not well defined, Dawkins turns to the genetics of race. Dawkins
describes the relatively low genetic variation between races, and geneticists conclusion that race is not an
important aspect of a person. These conclusions echo those of Lewontin, and Dawkins characterizes this view
as scientific orthodoxy. However, Dawkins felt that reasonable genetic conclusions had been tainted by
Lewontins politics. Dawkins accepted Lewontin's position that our perception of relatively large differences
between human races and subgroups, as compared to the variation within these groups, is a biased perception
and that human races and populations are remarkably similar to each other, with the largest part by far of human
variation being accounted for by the differences between individuals. Dawkins' also agreed with Lewontin that
racial classification had no social value, and was in fact destructive. Together with Edwards, Dawkins disagreed
with Lewontin that this means race is of 'virtually no genetic or taxonomic significance' and summarized
Edwards' point that however small the racial partition of the total variation may be, if such racial characteristics
as there are highly correlated with other racial characteristics, they are by definition informative, and therefore of
taxonomic significance. Dawkins went on to concludes that racial classification informs us about no more than
the traits common used to classify race: the superficial, external traits like eye shape and skin color.[34]
While acknowledging that FST remains useful, a number of scientists expressed its limitations.[35][36][37] Long &
Kittles (2009) stated that FST failed to identify important variation and that when the analysis includes only
humans, FST = 0.119, but adding chimpanzees increases it only to FST = 0.183.[35] Mountain & Risch (2004)
argued that an FST estimate of 0.10-0.15 does not rule out a genetic basis for phenotypic differences between
groups and that a low FST estimate implies little about the degree to which genes contribute to between-group

Print to PDF without this message by purchasing novaPDF (http://www.novapdf.com/)

differences.[36] Pearse & Crandall 2004 wrote that FST figures cannot distinguish between a situation of high
migration between populations with a long divergence time, and one of a relatively recent shared history but no
ongoing gene flow.[37]
Anthropologists (such as C. Loring Brace),[38] philosopher Jonathan Kaplan and geneticist Joseph Graves[39]
have argued that while it is possible to find biological and genetic variation roughly corresponding to race, this is
true for almost all geographically distinct populations: the cluster structure of genetic data is dependent on the
initial hypotheses of the researcher and the populations sampled. When one samples continental groups, the
clusters become continental; with other sampling patterns, the clusters would be different. Weiss and Fullerton
note that if one sampled only Icelanders, Mayans and Maoris, three distinct clusters would form; all other
populations would be composed of genetic admixtures of Maori, Icelandic and Mayan material.[40] Kaplan
therefore concludes that, while differences in particular allele frequencies can be used to identify populations that
loosely correspond to the racial categories common in Western social discourse, the differences are of no more
biological significance than the differences found between any human populations (e.g., the Spanish and
Portuguese).[41]

Self-identification
Jorde and Wooding (2004) wrote that clusters from genetic markers did not correspond to subjects' selfidentified race or ethnic group. However, the studies cited were based on relatively few genetic markers and
deemed insufficient. In contrast, studies based on a higher number of genetic markers have found more
agreement.[27]
A 2005 study by Tang and colleagues used 326 genetic markers to determine genetic clusters. The 3,636
subjects, from the United States and Taiwan, self-identified as belonging to white, African American, East Asian
or Hispanic ethnic groups. The study found "nearly perfect correspondence between genetic cluster and SIRE
for major ethnic groups living in the United States, with a discrepancy rate of only 0.14 percent".[6]
Paschou et al. (2010) found "essentially perfect" agreement between 51 self-identified populations and the
population's genetic structure, using 650,000 genetic markers. Selecting for informative genetic makers allowed
a reduction to less than 650, while retaining near-total accuracy.[42]
Correspondence between genetic clusters in a population (such as the current US population) and self-identified
race or ethnic groups does not mean that such a cluster (or group) corresponds to only one ethnic group.
African Americans have an estimated 1020-percent European genetic admixture; Hispanics have European,
Native American and African ancestry.[6] In Brazil there has been extensive admixture between Europeans,
Amerindians and Africans, resulting in no clear differences in skin color and relatively weak associations
between self-reported race and African ancestry.[43][44]

Genetic-distance increase
Genetic distances generally increase continually with geographic distance, which makes a dividing line arbitrary.
Any two neighboring settlements will exhibit some genetic difference from each other, which could be defined as
a race. Therefore, attempts to classify races impose an artificial discontinuity on a naturally occurring
phenomenon. This explains why studies on population genetic structure yield varying results, depending on
methodology.[45]

Print to PDF without this message by purchasing novaPDF (http://www.novapdf.com/)

Rosenberg and colleagues (2005) have argued, based on cluster analysis, that populations do not always vary
continuously and a population's genetic structure is consistent if enough genetic markers (and subjects) are
included. "Examination of the relationship between genetic and geographic distance supports a view in which the
clusters arise not as an artifact of the sampling scheme, but from small discontinuous jumps in genetic distance
for most population pairs on opposite sides of geographic barriers, in comparison with genetic distance for pairs
on the same side. Thus, analysis of the 993-locus dataset corroborates our earlier results: if enough markers are
used with a sufficiently large worldwide sample, individuals can be partitioned into genetic clusters that match
major geographic subdivisions of the globe, with some individuals from
intermediate geographic locations having mixed membership in the clusters that
correspond to neighboring regions." They also wrote, regarding a model with
five clusters corresponding to Africa, Eurasia (Europe, Middle East, and
Central/South Asia), East Asia, Oceania, and the Americas: "For population
pairs from the same cluster, as geographic distance increases, genetic distance
increases in a linear manner, consistent with a clinal population structure.
However, for pairs from different clusters, genetic distance is generally larger
than that between intracluster pairs that have the same geographic distance.
For example, genetic distances for population pairs with one population in
Eurasia and the other in East Asia are greater than those for pairs at equivalent
geographic distance within Eurasia or within East Asia. Loosely speaking, it is
these small discontinuous jumps in genetic distanceacross oceans, the
Himalayas, and the Saharathat provide the basis for the ability of
A change in a gene pool may
be abrupt or clinal.
STRUCTURE to identify clusters that correspond to geographic regions".[10]
This applies to populations in their ancestral homes when migrations and gene
flow were slow; large, rapid migrations exhibit different characteristics. Tang and colleagues (2004) wrote, "we
detected only modest genetic differentiation between different current geographic locales within each
race/ethnicity group. Thus, ancient geographic ancestry, which is highly correlated with self-identified
race/ethnicityas opposed to current residenceis the major determinant of genetic structure in the U.S.
population".[6]

Number of clusters
Cluster analysis has been criticized because the number of clusters to search for is decided in advance, with
different values possible (although with varying degrees of probability).[46] Principal component analysis does
not decide in advance how many components for which to search,[3] and it has been used in an increasing
number of studies.

Utility
It has been argued that knowledge of a person's race is limited in value, since people of the same race vary from
one another.[27] Witherspoon and colleagues (2007) have argued that when individuals are assigned to
population groups, two randomly chosen individuals from different populations can resemble each other more
than a randomly chosen member of their own group. They found that many thousands of genetic markers had to
be used for the answer to "How often is a pair of individuals from one population genetically more dissimilar than
two individuals chosen from two different populations?" to be "never". This assumed three population groups,
separated by large geographic distances (European, African and East Asian). The global human population is
more complex, and studying a large number of groups would require an increased number of markers for the
same answer. They conclude that "caution should be used when using geographic or genetic ancestry to make
inferences about individual phenotypes",[47] and "The fact that, given enough genetic data, individuals can be
correctly assigned to their populations of origin is compatible with the observation that most human genetic
Print to PDF without this message by purchasing novaPDF (http://www.novapdf.com/)

variation is found within populations, not between them. It is also compatible with our nding that, even when the
most distinct populations are considered and hundreds of loci are used, individuals are frequently more similar to
members of other populations than to members of their own population".[48]
This is similar to the conclusion reached by anthropologist Norman Sauer in a 1992 article on the ability of
forensic anthropologists to assign "race" to a skeleton, based on craniofacial features and limb morphology.
Sauer said, "the successful assignment of race to a skeletal specimen is not a vindication of the race concept, but
rather a prediction that an individual, while alive was assigned to a particular socially constructed 'racial'
category. A specimen may display features that point to African ancestry. In this country that person is likely to
have been labeled Black regardless of whether or not such a race actually exists in nature".[49]

Race and medicine


There are certain biological differences between racial groups in susceptibility to certain diseases.[50] Genes
change in response to local diseases; for example, people who are Duffy-negative tend to have a higher
resistance to malaria. The Duffy negative phenotype is highly frequent in central Africa and the frequency
decreases with distance away from Central Africa, with higher frequencies in global populations with high
degrees of recent African immigration. This suggests that the Duffy negative genotype evolved in Sub-Saharan
Africa and was subsequently positively selected for in the Malaria endemic zone.[51] A number of genetic
conditions prevalent in malaria-endemic areas may provide genetic resistance to malaria, including sickle cell
disease, thalassaemias and glucose-6-phosphate dehydrogenase. Cystic fibrosis is the most common life-limiting
autosomal recessive disease among people of European ancestry; a hypothesized heterozygote advantage,
providing resistance to diseases earlier common in Europe, has been challenged.[52]
Information about a person's population of origin may aid in diagnosis, and adverse drug responses may vary by
group.[7] Because of the correlation between self-identified race and genetic clusters, medical treatments
influenced by genetics have varying rates of success between self-defined racial groups.[53] For this reason,
some physicians consider a patient's race in choosing the most effective treatment,[54] and some drugs are
marketed with race-specific instructions.[55] Jorde and Wooding (2004) have argued that because of genetic
variation within racial groups, when "it finally becomes feasible and available, individual genetic assessment of
relevant genes will probably prove more useful than race in medical decision making". However, race continues
to be a factor when examining groups (such as epidemiologic research).[27]

See also
Y-chromosome haplogroups by populations
Human genetic clustering
History of anthropometry, section; 4.2 Race, identity and cranio-facial description
Regional: Archaeogenetics
Archaeogenetics of the Near East
Genetics and archaeogenetics of South Asia
Genetic history of Africa
Genetic history of Europe
Genetic history of Italy
Print to PDF without this message by purchasing novaPDF (http://www.novapdf.com/)

Genetic history of North Africa


Genetic history of indigenous peoples of the Americas
Genetic history of the Iberian Peninsula
Genetic history of the British Isles

References
1. ^ Sykes, Bryan (2001). "From Blood Groups to Genes". The seven daughters of Eve. New York: Norton.
pp. 3251. ISBN 0-393-02018-5.
2. ^ a b Cavalli-Sforza, L. L.; Menozzi, P.; Piazza, A. (1994). The history and geography of human genes.
Princeton, N.J: Princeton University Press. ISBN 9780691087504.
3. ^ a b Patterson, Nick; Price, Alkes L.; Reich, David (2006). "Population Structure and Eigenanalysis"
(https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1713260). PLoS Genetics 2 (12): e190.
doi:10.1371/journal.pgen.0020190 (http://dx.doi.org/10.1371%2Fjournal.pgen.0020190). PMC 1713260
(https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1713260). PMID 17194218
(https://www.ncbi.nlm.nih.gov/pubmed/17194218).
4. ^ a b Edwards AW (August 2003). "Human genetic diversity: Lewontin's fallacy". BioEssays 25 (8): 798801.
doi:10.1002/bies.10315 (http://dx.doi.org/10.1002%2Fbies.10315). PMID 12879450
(https://www.ncbi.nlm.nih.gov/pubmed/12879450).
5. ^ Witherspoon, D. J.; Wooding, S.; Rogers, A. R.; Marchani, E. E.; Watkins, W. S.; Batzer, M. A.; Jorde, L.
B. (2007). "Genetic Similarities Within and Between Human Populations"
(https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1893020). Genetics 176 (1): 351359.
doi:10.1534/genetics.106.067355 (http://dx.doi.org/10.1534%2Fgenetics.106.067355). PMC 1893020
(https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1893020). PMID 17339205
(https://www.ncbi.nlm.nih.gov/pubmed/17339205).
6. ^ a b c d e Tang H, Quertermous T, Rodriguez B, et al. (February 2005). "Genetic Structure, Self-Identified
Race/Ethnicity, and Confounding in Case-Control Association Studies"
(https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1196372). American Journal of Human Genetics 76 (2): 268
75. doi:10.1086/427888 (http://dx.doi.org/10.1086%2F427888). PMC 1196372
(https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1196372). PMID 15625622
(https://www.ncbi.nlm.nih.gov/pubmed/15625622).
7. ^ a b c d e f Rosenberg NA, Pritchard JK, Weber JL, et al. (December 2002). "Genetic structure of human
populations". Science 298 (5602): 23815. Bibcode:2002Sci...298.2381R
(http://adsabs.harvard.edu/abs/2002Sci...298.2381R). doi:10.1126/science.1078311
(http://dx.doi.org/10.1126%2Fscience.1078311). PMID 12493913
(https://www.ncbi.nlm.nih.gov/pubmed/12493913).
8. ^ Lewontin, R.C.. "Confusions About Human Races" (http://raceandgenomics.ssrc.org/Lewontin/).
9. ^ Kittles RA, Weiss KM (2003). "Race, ancestry, and genes: implications for defining disease risk". Annual
Review of Genomics and Human Genetics 4: 3367. doi:10.1146/annurev.genom.4.070802.110356
(http://dx.doi.org/10.1146%2Fannurev.genom.4.070802.110356). PMID 14527296
(https://www.ncbi.nlm.nih.gov/pubmed/14527296).
10. ^ a b c Rosenberg NA, Mahajan S, Ramachandran S, Zhao C, Pritchard JK, Feldman MW (December 2005).
"Clines, Clusters, and the Effect of Study Design on the Inference of Human Population Structure"
(https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1310579). PLoS Genetics 1 (6): e70.
Print to PDF without this message by purchasing novaPDF (http://www.novapdf.com/)

(https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1310579). PLoS Genetics 1 (6): e70.


doi:10.1371/journal.pgen.0010070 (http://dx.doi.org/10.1371%2Fjournal.pgen.0010070). PMC 1310579
(https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1310579). PMID 16355252
(https://www.ncbi.nlm.nih.gov/pubmed/16355252).
11. ^ Support from the relationship of genetic and geographic distance in human populations for a serial founder
effect originating in Africa (http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1276087)
12. ^ a b c d e f Genes, peoples, and languages, Luigi Luca Cavalli-Sforza, Proceedings of the National Academy of
Science, 1997, vol.94, pp.77197724, doi=10.1073/pnas.94.15.7719
http://www.pnas.org/cgi/content/full/94/15/7719
13. ^ a b Cavalli-Sforza, L. L., P. Menozzi, A. Piazza. 1994. The History and Geography of Human Genes.
Princeton University Press, Princeton. ISBN 0-691-02905-9
14. ^ Li, J. Z.; Absher, D. M.; Tang, H.; Southwick, A. M.; Casto, A. M.; Ramachandran, S.; Cann, H. M.; Barsh,
G. S.; Feldman, M.; Cavalli-Sforza, L. L.; Myers, R. M. (2008). "Worldwide Human Relationships Inferred
from Genome-Wide Patterns of Variation". Science 319 (5866): 11001104. Bibcode:2008Sci...319.1100L
(http://adsabs.harvard.edu/abs/2008Sci...319.1100L). doi:10.1126/science.1153717
(http://dx.doi.org/10.1126%2Fscience.1153717). PMID 18292342
(https://www.ncbi.nlm.nih.gov/pubmed/18292342).
15. ^ Jakobsson, M.; Scholz, S. W.; Scheet, P.; Gibbs, J. R.; Vanliere, J. M.; Fung, H. C.; Szpiech, Z. A.;
Degnan, J. H.; Wang, K.; Guerreiro, R.; Bras, J. M.; Schymick, J. C.; Hernandez, D. G.; Traynor, B. J.;
Simon-Sanchez, J.; Matarin, M.; Britton, A.; Van De Leemput, J.; Rafferty, I.; Bucan, M.; Cann, H. M.; Hardy,
J. A.; Rosenberg, N. A.; Singleton, A. B. (2008). "Genotype, haplotype and copy-number variation in
worldwide human populations". Nature 451 (7181): 9981003. Bibcode:2008Natur.451..998J
(http://adsabs.harvard.edu/abs/2008Natur.451..998J). doi:10.1038/nature06742
(http://dx.doi.org/10.1038%2Fnature06742). PMID 18288195
(https://www.ncbi.nlm.nih.gov/pubmed/18288195).
16. ^ Xing, J.; Watkins, W. S.; Witherspoon, D. J.; Zhang, Y.; Guthery, S. L.; Thara, R.; Mowry, B. J.; Bulayeva,
K.; Weiss, R. B.; Jorde, L. B. (2009). "Fine-scaled human genetic structure revealed by SNP microarrays"
(https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2675970). Genome Research 19 (5): 815825.
doi:10.1101/gr.085589.108 (http://dx.doi.org/10.1101%2Fgr.085589.108). PMC 2675970
(https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2675970). PMID 19411602
(https://www.ncbi.nlm.nih.gov/pubmed/19411602).
17. ^ Lpez Herrez, D.; Bauchet, M.; Tang, K.; Theunert, C.; Pugach, I.; Li, J.; Nandineni, M. R.; Gross, A.;
Scholz, M.; Stoneking, M. (2009). "Genetic Variation and Recent Positive Selection in Worldwide Human
Populations: Evidence from Nearly 1 Million SNPs"
(https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2775638). In Hawks, John. PLoS ONE 4 (11): e7888.
Bibcode:2009PLoSO...4.7888L (http://adsabs.harvard.edu/abs/2009PLoSO...4.7888L).
doi:10.1371/journal.pone.0007888 (http://dx.doi.org/10.1371%2Fjournal.pone.0007888). PMC 2775638
(https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2775638). PMID 19924308
(https://www.ncbi.nlm.nih.gov/pubmed/19924308).
18. ^ Report by Masatoshi Nei and Arun K (http://www.racialcompact.com/Race_%20Realityand%20Denial.html)
19. ^ Peter J. Taylor's schematic map (http://pjt111.wordpress.com/2011/04/21/depictions-of-human-geneticrelationships-3/)
20. ^ "Do Races Differ? Not Really, DNA Shows" (http://partners.nytimes.com/library/national/science/082200scigenetics-race.html). The New York Times. 22 August 2000.
21. ^ McDonald, J; Lehman, DC (Spring 2012). "Forensic DNA analysis.". Clinical laboratory science : journal of
Print to PDF without this message by purchasing novaPDF (http://www.novapdf.com/)

21. ^ McDonald, J; Lehman, DC (Spring 2012). "Forensic DNA analysis.". Clinical laboratory science : journal of
the American Society for Medical Technology 25 (2): 10913. PMID 22693781
(https://www.ncbi.nlm.nih.gov/pubmed/22693781).
22. ^ Butler, John. Genetics and Genomics of Core STR Loci Used in Human Identity Testing*
(http://www.cstl.nist.gov/div831/strbase/pub_pres/Butler_coreSTRloci_JFS_Mar2006.pdf).
23. ^ Genetics and Genomics of Core STR Loci Used in Human Identity Testing*
(http://www.omicsonline.org/2157-7145/2157-7145-3-170.pdf). doi:10.4172/2157-7145.1000170
(http://dx.doi.org/10.4172%2F2157-7145.1000170).
24. ^ a b Redd, AJ; Chamberlain, VF; Kearney, VF; Stover, D; Karafet, T; Calderon, K; Walsh, B; Hammer, MF
(May 2006). "Genetic structure among 38 populations from the United States based on 11 U.S. core Y
chromosome STRs.". Journal of forensic sciences 51 (3): 5805. doi:10.1111/j.1556-4029.2006.00113.x
(http://dx.doi.org/10.1111%2Fj.1556-4029.2006.00113.x). PMID 16696705
(https://www.ncbi.nlm.nih.gov/pubmed/16696705).
25. ^ Hammer, MF; Chamberlain, VF; Kearney, VF; Stover, D; Zhang, G; Karafet, T; Walsh, B; Redd, AJ (Dec 1,
2006). "Population structure of Y chromosome SNP haplogroups in the United States and forensic implications
for constructing Y chromosome STR databases." (http://www.fsijournal.org/article/S0379-0738(05)006158/abstract). Forensic Science International 164 (1): 4555. doi:10.1016/j.forsciint.2005.11.013
(http://dx.doi.org/10.1016%2Fj.forsciint.2005.11.013). PMID 16337103
(https://www.ncbi.nlm.nih.gov/pubmed/16337103).
26. ^ Sims, LM; Ballantyne, J (March 2008). "The golden gene (SLC24A5) differentiates US sub-populations
within the ethnically admixed Y-SNP haplogroups." (https://www.ncjrs.gov/pdffiles1/nij/grants/211979.pdf).
Legal medicine (Tokyo, Japan) 10 (2): 727. doi:10.1016/j.legalmed.2007.06.004
(http://dx.doi.org/10.1016%2Fj.legalmed.2007.06.004). PMID 17720606
(https://www.ncbi.nlm.nih.gov/pubmed/17720606).
27. ^ a b c d Jordge, Lynn B. and Stephen P. Wooding. "Genetic Variation, classification and 'race'". Nature, Vol. 36
Num. 11, November 2004.
28. ^ Long, Jeffrey C.; Li, Jie; Healy, Meghan E. (2009). "Human DNA sequences: More variation and less race".
American Journal of Physical Anthropology 139 (1): 2334. doi:10.1002/ajpa.21011
(http://dx.doi.org/10.1002%2Fajpa.21011). PMID 19226648
(https://www.ncbi.nlm.nih.gov/pubmed/19226648).
29. ^ Lewontin, R. C. (1972). "The Apportionment of Human Diversity" (http://www.philbio.org/wpcontent/uploads/2010/11/Lewontin-The-Apportionment-of-Human-Diversity.pdf). Evolutionary Biology 6 (38):
391398. doi:10.1007/978-1-4684-9063-3_14 (http://dx.doi.org/10.1007%2F978-1-4684-9063-3_14).
30. ^ Risch, Neil; Burchard, Esteban; Ziv, Elad; Tang, Hua (2002). "Categorization of humans in biomedical
research: genes, race and disease" (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC139378). Genome Biology
3 (7): comment2007.1. doi:10.1186/gb-2002-3-7-comment2007 (http://dx.doi.org/10.1186%2Fgb-2002-3-7comment2007). PMC 139378 (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC139378). PMID 12184798
(https://www.ncbi.nlm.nih.gov/pubmed/12184798).
31. ^ Templeton, Alan R. (2003). "Human Races in the Context of Recent Human Evolution: A Molecular Genetic
Perspective"
(http://slava.parma.ru/Doc/Unsorted/New/BOOKS/Genetic.Nature.Culture.Anthropology.And.Science.Beyond.T
he.Two-Culture.Divide.eBook-LiB.pdf#page=254). In Goodman, Alan H.; Heath, Deborah; Lindee, M. Susan.
Genetic nature/culture: anthropology and science beyond the two-culture divide. Berkeley: University of
California Press. pp. 234257. ISBN 0-520-23792-7.
32. ^ Ossorio and Duster, 2005
Print to PDF without this message by purchasing novaPDF (http://www.novapdf.com/)

32. ^ Ossorio and Duster, 2005


33. ^ Lewontin, R. C. (2005). Confusions About Human Races (http://raceandgenomics.ssrc.org/Lewontin/) from
Race and Genomics, Social Sciences Research Council. Retrieved 28 December 2006.
34. ^ Dawkins, Richard; Wong, Yan (2005). The Ancestor's Tale: A Pilgrimage to the Dawn of Evolution
(http://books.google.com/?
id=rR9XPnaqvCMC&pg=PA406&dq=%22Lewontin's+Fallacy%22#v=onepage&q=%22Lewontin's%20Fallacy
%22&f=false). Houghton Mifflin Harcourt. pp. 406407. ISBN 978-0-618-61916-0. Retrieved July 13, 2011.
35. ^ a b Long, J.C. & Kittles, R.A. (2009). "Human genetic diversity and the nonexistence of biological races"
(http://www.ncbi.nlm.nih.gov/pubmed/14655871). Human Biology 81 (5/6): 777798.
doi:10.3378/027.081.0621 (http://dx.doi.org/10.3378%2F027.081.0621).
36. ^ a b Mountain, J.L. & Risch, N (2004). "Assessing genetic contributions to phenotypic differences among
'racial' and 'ethnic' groups" (http://www.nature.com/ng/journal/v36/n11s/full/ng1456.html). Nature Genetics 36:
S48 S53. doi:10.1038/ng1456 (http://dx.doi.org/10.1038%2Fng1456).
37. ^ a b Pearse, D. E., & Crandall, K. A. "Beyond FST: analysis of population genetic data for conservation"
(http://link.springer.com/article/10.1007/s10592-003-1863-4). Conservation Genetics 5 (5): 585602.
doi:10.1007/s10592-003-1863-4 (http://dx.doi.org/10.1007%2Fs10592-003-1863-4).
38. ^ Loring Brace, C. 2005. Race is a four letter word. Oxford University Press.
39. ^ Graves, Joseph. 2001. The Emperor's New Clothes. Rutgers University Press
40. ^ Weiss KM and Fullerton SM (2005) Racing around, getting nowhere. Evolutionary Anthropology 14: 165
169
41. ^ Kaplan, J. M. (2011). "'Race': What Biology Can Tell Us about a Social Construct"
(http://www.els.net/WileyCDA/ElsArticle/refId-a0005857.html). Encyclopedia of Life Sciences (ELS)
(Chichester: John Wiley & Sons, Ltd). doi:10.1002/9780470015902.a0005857
(http://dx.doi.org/10.1002%2F9780470015902.a0005857).
42. ^ Ancestry informative markers for fine-scale individual assignment to worldwide populations, Peristera
Paschou, Jamey Lewis, Asif Javed, Petros Drineas, J Med Genet doi:10.1136/jmg.2010.078212
(http://dx.doi.org/10.1136%2Fjmg.2010.078212)
43. ^ Pena, Srgio D. J.; Di Pietro, Giuliano; Fuchshuber-Moraes, Mateus; Genro, Julia Pasqualini; Hutz, Mara H.;
Kehdy, Fernanda de Souza Gomes; Kohlrausch, Fabiana; Magno, Luiz Alexandre Viana; Montenegro, Raquel
Carvalho; Moraes, Manoel Odorico; de Moraes, Maria Elisabete Amaral; de Moraes, Milene Raiol; Ojopi, lida
B.; Perini, Jamila A.; Racciopi, Clarice; Ribeiro-dos-Santos, ndrea Kely Campos; Rios-Santos, Fabrcio;
Romano-Silva, Marco A.; Sortica, Vinicius A.; Suarez-Kurtz, Guilherme (2011). "The Genomic Ancestry of
Individuals from Different Geographical Regions of Brazil is More Uniform Than Expected"
(https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040205). In Harpending, Henry. PLoS ONE 6 (2): e17063.
Bibcode:2011PLoSO...6E7063P (http://adsabs.harvard.edu/abs/2011PLoSO...6E7063P).
doi:10.1371/journal.pone.0017063 (http://dx.doi.org/10.1371%2Fjournal.pone.0017063). PMC 3040205
(https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040205). PMID 21359226
(https://www.ncbi.nlm.nih.gov/pubmed/21359226).
44. ^ Parra, F. C. (2002). "Color and genomic ancestry in Brazilians"
(https://www.ncbi.nlm.nih.gov/pmc/articles/PMC140919). Proceedings of the National Academy of Sciences
100 (1): 17782. Bibcode:2002PNAS..100..177P (http://adsabs.harvard.edu/abs/2002PNAS..100..177P).
doi:10.1073/pnas.0126614100 (http://dx.doi.org/10.1073%2Fpnas.0126614100). PMC 140919
(https://www.ncbi.nlm.nih.gov/pmc/articles/PMC140919). PMID 12509516
(https://www.ncbi.nlm.nih.gov/pubmed/12509516).
45. ^ Back with a Vengeance: the Reemergence of a Biological Conceptualization of Race in Research on
Print to PDF without this message by purchasing novaPDF (http://www.novapdf.com/)

45.

Back with a Vengeance: the Reemergence of a Biological Conceptualization of Race in Research on


Race/Ethnic Disparities in Health Reanne Frank (http://paa2006.princeton.edu/download.aspx?
submissionId=61713)

46. ^ Bolnick, Deborah A. (2008). "Individual Ancestry Inference and the Reification of Race as a Biological
Phenomenon". In Koenig, Barbara A.; Richardson, Sarah S.; Lee, Sandra Soo-Jin. Revisiting race in a genomic
age. Rutgers University Press. ISBN 978-0-8135-4324-6.
47. ^ Witherspoon DJ, Wooding S, Rogers AR, et al. (May 2007). "Genetic Similarities Within and Between
Human Populations" (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1893020). Genetics 176 (1): 3519.
doi:10.1534/genetics.106.067355 (http://dx.doi.org/10.1534%2Fgenetics.106.067355). PMC 1893020
(https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1893020). PMID 17339205
(https://www.ncbi.nlm.nih.gov/pubmed/17339205).
48. ^ Witherspoon DJ, Wooding S, Rogers AR, et al. (May 2007). "Genetic Similarities Within and Between
Human Populations" (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1893020). Genetics 176 (1): 358.
doi:10.1534/genetics.106.067355 (http://dx.doi.org/10.1534%2Fgenetics.106.067355). PMC 1893020
(https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1893020). PMID 17339205
(https://www.ncbi.nlm.nih.gov/pubmed/17339205).
49. ^ Sauer 1992
50. ^ Risch N (July 2005). "The whole side of it--an interview with Neil Risch by Jane Gitschier". PLoS Genetics 1
(1): e14. doi:10.1371/journal.pgen.0010014 (http://dx.doi.org/10.1371%2Fjournal.pgen.0010014).
PMID 17411332 (https://www.ncbi.nlm.nih.gov/pubmed/17411332).
51. ^ Malaria and the Red Cell, Harvard University. 2002 url=http://sickle.bwh.harvard.edu/malaria_sickle.html
52. ^ Hgenauer C, Santa Ana CA, Porter JL, et al. (December 2000). "Active intestinal chloride secretion in
human carriers of cystic fibrosis mutations: an evaluation of the hypothesis that heterozygotes have subnormal
active intestinal chloride secretion" (http://linkinghub.elsevier.com/retrieve/pii/S0002-9297(07)63211-X). Am. J.
Hum. Genet. 67 (6): 14227. doi:10.1086/316911 (http://dx.doi.org/10.1086%2F316911). PMC 1287919
(https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1287919). PMID 11055897
(https://www.ncbi.nlm.nih.gov/pubmed/11055897).
53. ^ Racial Differences in the Response to Drugs Pointers to Genetic Differences
(http://content.nejm.org/cgi/content/extract/344/18/1393). New England Journal of Medicine, Volume
344:1393-1396, May 3, 2001.
54. ^ Bloche, Gregg M. Race-Based Therapeutics (http://content.nejm.org/cgi/content/full/351/20/2035). New
England Journal of Medicine, Volume 351:2035-2037, November 11, 2004.
55. ^ Drug information for the drug Crestor. (http://www.emedicinehealth.com/drug-rosuvastatin/article_em.htm)
Warnings for this drug state, "People of Asian descent may absorb rosuvastatin at a higher rate than other
people. Make sure your doctor knows if you are Asian. You may need a lower than normal starting dose."

Further reading
Helms JE, Jernigan M, Mascher J (January 2005). "The meaning of race in psychology and how to change it: a
methodological perspective". The American Psychologist 60 (1): 2736. doi:10.1037/0003-066X.60.1.27
(http://dx.doi.org/10.1037%2F0003-066X.60.1.27). PMID 15641919
(https://www.ncbi.nlm.nih.gov/pubmed/15641919).
Jackson FL (2004). "Human genetic variation and health: new assessment approaches based on ethnogenetic
layering". British Medical Bulletin 69: 21535. doi:10.1093/bmb/ldh012
(http://dx.doi.org/10.1093%2Fbmb%2Fldh012). PMID 15226208
Print to PDF without this message by purchasing novaPDF (http://www.novapdf.com/)

(https://www.ncbi.nlm.nih.gov/pubmed/15226208).
Keita, Shomarka O. Y. (March 1993). "The Subspecies Concept in Zoology and Anthropology: A Brief
Historical Review and Test of a Classification Scheme". Journal of Black Studies 23 (3): 41645.
doi:10.1177/002193479302300309 (http://dx.doi.org/10.1177%2F002193479302300309).
Keita SO, Kittles RA, Royal CD, et al. (November 2004). "Conceptualizing human variation". Nature Genetics
36 (11 Suppl): S1720. doi:10.1038/ng1455 (http://dx.doi.org/10.1038%2Fng1455). PMID 15507998
(https://www.ncbi.nlm.nih.gov/pubmed/15507998).
Leroi, Armand Marie (March 14, 2005). "A Family Tree in Every Gene"
(http://www.nytimes.com/2005/03/14/opinion/14leroi.html). The New York Times. Retrieved February 2, 2010.
Lieberman, Leonard; Kirk, Rodney C.; Corcoran, Michael (2003). "The Decline of Race in American Physical
Anthropology" (http://www.staff.amu.edu.pl/~anthro/pdf/paar/vol066/01lieb.pdf). Przegld Antropologiczny
Anthropological Review 66: 321. ISSN 0033-2003 (https://www.worldcat.org/issn/0033-2003).
Long JC, Kittles RA (August 2003). "Human genetic diversity and the nonexistence of biological races". Human
Biology 75 (4): 44971. doi:10.1353/hub.2003.0058 (http://dx.doi.org/10.1353%2Fhub.2003.0058).
PMID 14655871 (https://www.ncbi.nlm.nih.gov/pubmed/14655871).
Miththapala, Sriyanie; Seidensticker, John; O'Brien, Stephen J. (1996). "Phylogeographic Subspecies
Recognition in Leopards (Panthera pardus): Molecular Genetic Variation". Conservation Biology 10 (4): 1115.
doi:10.1046/j.1523-1739.1996.10041115.x (http://dx.doi.org/10.1046%2Fj.1523-1739.1996.10041115.x).
Ossorio P, Duster T (January 2005). "Race and genetics: controversies in biomedical, behavioral, and forensic
sciences". The American Psychologist 60 (1): 11528. doi:10.1037/0003-066X.60.1.115
(http://dx.doi.org/10.1037%2F0003-066X.60.1.115). PMID 15641926
(https://www.ncbi.nlm.nih.gov/pubmed/15641926).
Parra EJ, Kittles RA, Shriver MD (November 2004). "Implications of correlations between skin color and
genetic ancestry for biomedical research". Nature Genetics 36 (11 Suppl): S5460. doi:10.1038/ng1440
(http://dx.doi.org/10.1038%2Fng1440). PMID 15508005 (https://www.ncbi.nlm.nih.gov/pubmed/15508005).
Sawyer SL, Mukherjee N, Pakstis AJ, et al. (May 2005). "Linkage disequilibrium patterns vary substantially
among populations". European Journal of Human Genetics 13 (5): 67786. doi:10.1038/sj.ejhg.5201368
(http://dx.doi.org/10.1038%2Fsj.ejhg.5201368). PMID 15657612
(https://www.ncbi.nlm.nih.gov/pubmed/15657612).
Rohde DL, Olson S, Chang JT (September 2004). "Modelling the recent common ancestry of all living
humans". Nature 431 (7008): 5626. Bibcode:2004Natur.431..562R
(http://adsabs.harvard.edu/abs/2004Natur.431..562R). doi:10.1038/nature02842
(http://dx.doi.org/10.1038%2Fnature02842). PMID 15457259
(https://www.ncbi.nlm.nih.gov/pubmed/15457259).
Serre D, Pbo S (September 2004). "Evidence for Gradients of Human Genetic Diversity Within and Among
Continents" (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC515312). Genome Research 14 (9): 167985.
doi:10.1101/gr.2529604 (http://dx.doi.org/10.1101%2Fgr.2529604). PMC 515312
(https://www.ncbi.nlm.nih.gov/pmc/articles/PMC515312). PMID 15342553
(https://www.ncbi.nlm.nih.gov/pubmed/15342553).
Smedley A, Smedley BD (January 2005). "Race as biology is fiction, racism as a social problem is real:
Anthropological and historical perspectives on the social construction of race". The American Psychologist 60
(1): 1626. doi:10.1037/0003-066X.60.1.16 (http://dx.doi.org/10.1037%2F0003-066X.60.1.16).
PMID 15641918 (https://www.ncbi.nlm.nih.gov/pubmed/15641918).
Barbara A. Koenig, Sandra Soo-Jin Lee, Sarah S. Richardson, ed. (January 2005). "Revisiting race in a genomic

Print to PDF without this message by purchasing novaPDF (http://www.novapdf.com/)

age". American Psychologist (Rutgers University Press) 60 (1): 1626. doi:10.1037/0003-066X.60.1.16


(http://dx.doi.org/10.1037%2F0003-066X.60.1.16). ISBN 978-0-8135-4324-6. PMID 15641918
(https://www.ncbi.nlm.nih.gov/pubmed/15641918).
Barbara A. Koenig, Sandra Soo-Jin Lee, Sarah S. Richardson, ed. (2008). Revisiting race in a genomic age.
Rutgers University Press. ISBN 978-0-8135-4324-6.
Marsh SG (October 2011). "Race and Genetics in Stem Cell Transplantation"
(http://www.bionews.org.uk/page_109729.asp). BioNews 629.

Retrieved from "http://en.wikipedia.org/w/index.php?title=Race_and_genetics&oldid=615048953"


Categories: Genetic genealogy Race (human classification) Population genetics Human genetics
Biological anthropology
This page was last modified on 30 June 2014 at 18:26.
Text is available under the Creative Commons Attribution-ShareAlike License; additional terms may
apply. By using this site, you agree to the Terms of Use and Privacy Policy. Wikipedia is a registered
trademark of the Wikimedia Foundation, Inc., a non-profit organization.

Print to PDF without this message by purchasing novaPDF (http://www.novapdf.com/)