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Scopus - Print - 147 (August 2014)

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Documents
Gunn, R.N., Rabiner, E.A.
PET neuroimaging: The elephant unpacks his trunk: Comment on cumming: PET neuroimaging: The white elephant
packs his trunk?
(2014) NeuroImage, 94, pp. 408-410.
Document Type: Note
Source: Scopus
Colasanti, A., Guo, Q., Muhlert, N., Giannetti, P., Onega, M., Newbould, R.D., Ciccarelli, O., Rison, S., Thomas, C., Nicholas,
R., Muraro, P.A., Malik, O., Owen, D.R., Piccini, P., Gunn, R.N., Rabiner, E.A., Matthews, P.M.
In vivo assessment of brain white matter inflammation in multiple sclerosis with 18F-PBR111 PET
(2014) Journal of Nuclear Medicine, 55 (7), pp. 1112-1118.
Document Type: Article
Source: Scopus
Mick, I., Myers, J., Stokes, P.R.A., Erritzoe, D., Colasanti, A., Bowden-Jones, H., Clark, L., Gunn, R.N., Rabiner, E.A., Searle,
G.E., Waldman, A.D., Parkin, M.C., Brailsford, A.D., Nutt, D.J., Lingford-Hughes, A.R.
Amphetamine induced endogenous opioid release in the human brain detected with [11C]carfentanil PET:
replication in an independent cohort
(2014) International Journal of Neuropsychopharmacology, pp. 1-6. Article in Press.
Document Type: Article in Press
Source: Scopus
Plisson, C., Plisson, D., Jakobsen, S., Natesan, S., Salinas, C., Lin, S.-F., Labaree, D., Zheng, M.-Q., Nabulsi, N., Marques,
T.R., Kapur, S., Kawanishi, E., Saijo, T., Gunn, R.N., Carson, R.E., Rabiner, E.A.
Phosphodiesterase 10a pet radioligand development program: From pig to human
(2014) Journal of Nuclear Medicine, 55 (4), pp. 595-601.
Document Type: Article
Source: Scopus
Natesan, S., Ashworth, S., Nielsen, J., Tang, S.-P., Salinas, C., Kealey, S., Lauridsen, J.B., Stensbl, T.B., Gunn, R.N.,
Rabiner, E.A., Kapur, S.
Effect of chronic antipsychotic treatment on striatal phosphodiesterase 10A levels: A [11C]MP-10 PET rodent
imaging study with ex vivo confirmation
(2014) Translational Psychiatry, 4, art. no. e376, .
Document Type: Article
Source: Scopus
Ashworth, S., Berges, A., Rabiner, E.A., Wilson, A.A., Comley, R.A., Lai, R.Y.K., Boardley, R., Searle, G., Gunn, R.N.,
Laruelle, M., Cunningham, V.J.
Unexpectedly high affinity of a novel histamine H3 receptor antagonist, GSK239512, in vivo in human brain,
determined using PET
(2014) British Journal of Pharmacology, 171 (5), pp. 1241-1249.
Document Type: Article
Source: Scopus

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Gunn, R., Rabiner, I.


Making drug development visible - And viable
(2014) Drug Discovery Today, 19 (1), pp. 1-3.
Document Type: Review
Source: Scopus
Owen, D.R., Guo, Q., Kalk, N.J., Colasanti, A., Kalogiannopoulou, D., Dimber, R., Lewis, Y.L., Libri, V., Barletta, J., RamadaMagalhaes, J., Kamalakaran, A., Nutt, D.J., Passchier, J., Matthews, P.M., Gunn, R.N., Rabiner, E.A.
Determination of [11C]PBR28 binding potential in vivo: A first human TSPO blocking study
(2014) Journal of Cerebral Blood Flow and Metabolism, 34 (6), pp. 989-994. Cited 1 time.
Document Type: Article
Source: Scopus
Tziortzi, A.C., Haber, S.N., Searle, G.E., Tsoumpas, C., Long, C.J., Shotbolt, P., Douaud, G., Jbabdi, S., Behrens, T.E.J.,
Rabiner, E.A., Jenkinson, M., Gunn, R.N.
Connectivity-based functional analysis of dopamine release in the striatum using diffusion-weighted MRI and
positron emission tomography
(2014) Cerebral Cortex, 24 (5), pp. 1165-1177. Cited 2 times.
Document Type: Article
Source: Scopus
Guo, Q., Owen, D.R., Rabiner, E.A., Turkheimer, F.E., Gunn, R.N.
A graphical method to compare the in vivo binding potential of PET radioligands in the absence of a reference
region: Application to [ 11 C]PBR28 and [ 18 F]PBR111 for TSPO imaging
(2014) Journal of Cerebral Blood Flow and Metabolism, 34 (7), pp. 1162-1168.
Document Type: Article
Source: Scopus
Jiao, J., Searle, G.E., Tziortzi, A.C., Salinas, C.A., Gunn, R.N., Schnabel, J.A.
Spatio-temporal pharmacokinetic model based registration of 4D PET neuroimaging data
(2014) NeuroImage, 84, pp. 225-235.
Document Type: Article
Source: Scopus
Erritzoe, D., Tziortzi, A., Bargiela, D., Colasanti, A., Searle, G.E., Gunn, R.N., Beaver, J.D., Waldman, A., Nutt, D.J., Bani,
M., Merlo-Pich, E., Rabiner, E.A., Lingford-Hughes, A.
In vivo imaging of cerebral dopamine D3 receptors in alcoholism
(2014) Neuropsychopharmacology, 39 (7), pp. 1703-1712. Cited 1 time.
Document Type: Article
Source: Scopus
Ridler, K., Gunn, R.N., Searle, G.E., Barletta, J., Passchier, J., Dixson, L., Hallett, W.A., Ashworth, S., Gray, F.A., Burgess,
C., Poggesi, I., Bullman, J.N., Ratti, E., Laruelle, M.A., Rabiner, E.A.
Characterising the plasma-target occupancy relationship of the neurokinin antagonist GSK1144814 with PET
(2014) Journal of Psychopharmacology, 28 (3), pp. 244-253.
Document Type: Article
Source: Scopus
Jiao, J., Schnabel, J.A., Gunn, R.N.
A generalised spatio-temporal registration framework for dynamic PET data: application to neuroreceptor imaging.
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(2013) Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image
Computing and Computer-Assisted Intervention, 16 (Pt 1), pp. 211-218.
Document Type: Article
Source: Scopus
Guo, Q., Colasanti, A., Owen, D.R., Onega, M., Kamalakaran, A., Bennacef, I., Matthews, P.M., Rabiner, E.A., Turkheimer,
F.E., Gunn, R.N.
Quantification of the specific translocator protein signal of 18F-PBR111 in healthy humans: A genetic polymorphism
effect on in vivo Binding
(2013) Journal of Nuclear Medicine, 54 (11), pp. 1915-1923. Cited 5 times.
Document Type: Article
Source: Scopus
Jiao, J., Schnabel, J.A., Gunn, R.N.
A generalised spatio-temporal registration framework for dynamic PET data: Application to neuroreceptor imaging
(2013) Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in
Bioinformatics), 8149 LNCS (PART 1), pp. 211-218.
Document Type: Conference Paper
Source: Scopus
Comley, R.A., Salinas, C.A., Slifstein, M., Petrone, M., Marzano, C., Bennacef, I., Shotbolt, P., Van Der Aart, J., Neve, M.,
Iavarone, L., Gomeni, R., Laruelle, M., Gray, F.A., Gunn, R.N., Rabiner, E.A.
Monoamine transporter occupancy of a novel triple reuptake inhibitor in baboons and humans using positron
emission tomography
(2013) Journal of Pharmacology and Experimental Therapeutics, 346 (2), pp. 311-317. Cited 2 times.
Document Type: Article
Source: Scopus
Berges, A., Cunningham, V.J., Gunn, R.N., Zamuner, S.
Non linear mixed effects analysis in PET PK-receptor occupancy studies
(2013) NeuroImage, 76, pp. 155-166.
Document Type: Article
Source: Scopus
Salinas, C., Weinzimmer, D., Searle, G., Labaree, D., Ropchan, J., Huang, Y., Rabiner, E.A., Carson, R.E., Gunn, R.N.
Kinetic analysis of drug-target interactions with PET for characterization of pharmacological hysteresis
(2013) Journal of Cerebral Blood Flow and Metabolism, 33 (5), pp. 700-707. Cited 1 time.
Document Type: Article
Source: Scopus
Searle, G.E., Beaver, J.D., Tziortzi, A., Comley, R.A., Bani, M., Ghibellini, G., Merlo-Pich, E., Rabiner, E.A., Laruelle, M.,
Gunn, R.N.
Mathematical modelling of [11C]-(+)-PHNO human competition studies
(2013) NeuroImage, 68, pp. 119-132. Cited 8 times.
Document Type: Article
Source: Scopus
Veronese, M., Gunn, R.N., Zamuner, S., Bertoldo, A.
A non-linear mixed effect modelling approach for metabolite correction of the arterial input function in PET studies
(2013) NeuroImage, 66, pp. 611-622.

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Document Type: Article


Source: Scopus
Cole, D.M., Beckmann, C.F., Searle, G.E., Plisson, C., Tziortzi, A.C., Nichols, T.E., Gunn, R.N., Matthews, P.M., Rabiner,
E.A., Beaver, J.D.
Orbitofrontal connectivity with resting-state networks is associated with midbrain dopamine D3 receptor availability
(2012) Cerebral Cortex, 22 (12), pp. 2784-2793. Cited 13 times.
Document Type: Article
Source: Scopus
Jiao, J., Searle, G.E., Tziortzi, A.C., Salinas, C.A., Gunn, R.N., Schnabel, J.A.
Spatial-temporal pharmacokinetic model based registration of 4D brain PET data
(2012) Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in
Bioinformatics), 7570 LNCS, pp. 100-112. Cited 2 times.
Document Type: Conference Paper
Source: Scopus
Colasanti, A., Searle, G.E., Long, C.J., Hill, S.P., Reiley, R.R., Quelch, D., Erritzoe, D., Tziortzi, A.C., Reed, L.J., LingfordHughes, A.R., Waldman, A.D., Schruers, K.R.J., Matthews, P.M., Gunn, R.N., Nutt, D.J., Rabiner, E.A.
Endogenous opioid release in the human brain reward system induced by acute amphetamine administration
(2012) Biological Psychiatry, 72 (5), pp. 371-377. Cited 12 times.
Document Type: Article
Source: Scopus
Gallezot, J.-D., Beaver, J.D., Gunn, R.N., Nabulsi, N., Weinzimmer, D., Singhal, T., Slifstein, M., Fowles, K., Ding, Y.-S.,
Huang, Y., Laruelle, M., Carson, R.E., Rabiner, E.A.
Affinity and selectivity of [ 11C]-(+)-PHNO for the D3 and D2 receptors in the rhesus monkey brain in vivo
(2012) Synapse, 66 (6), pp. 489-500. Cited 22 times.
Document Type: Article
Source: Scopus
Jiao, J., Salinas, C.A., Searle, G.E., Gunn, R.N., Schnabel, J.A.
Joint estimation of subject motion and tracer kinetic parameters of dynamic PET data in an EM framework
(2012) Progress in Biomedical Optics and Imaging - Proceedings of SPIE, 8314, art. no. 83140A, .
Document Type: Conference Paper
Source: Scopus
Gunn, R.N., Summerfield, S.G., Salinas, C.A., Read, K.D., Guo, Q., Searle, G.E., Parker, C.A., Jeffrey, P., Laruelle, M.
Combining PET biodistribution and equilibrium dialysis assays to assess the free brain concentration and BBB
transport of CNS drugs
(2012) Journal of Cerebral Blood Flow and Metabolism, 32 (5), pp. 874-883. Cited 9 times.
Document Type: Article
Source: Scopus
Guo, Q., Owen, D.R., Rabiner, E.A., Turkheimer, F.E., Gunn, R.N.
Identifying improved TSPO PET imaging probes through biomathematics: The impact of multiple TSPO binding
sites in vivo
(2012) NeuroImage, 60 (2), pp. 902-910. Cited 8 times.
Document Type: Article
Source: Scopus

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Parker, C.A., Gunn, R.N., Rabiner, E.A., Slifstein, M., Comley, R., Salinas, C., Johnson, C.N., Jakobsen, S., Houle, S.,
Laruelle, M., Cunningham, V.J., Martarello, L.
Radiosynthesis and characterization of 11C-GSK215083 as a PET radioligand for the 5-HT6 receptor
(2012) Journal of Nuclear Medicine, 53 (2), pp. 295-303. Cited 8 times.
Document Type: Article
Source: Scopus
Matthews, P.M., Rabiner, E.A., Passchier, J., Gunn, R.N.
Positron emission tomography molecular imaging for drug development
(2012) British Journal of Clinical Pharmacology, 73 (2), pp. 175-186. Cited 28 times.
Document Type: Article
Source: Scopus
Zamuner, S., Rabiner, E.A., Fernandes, S.A., Bani, M., Gunn, R.N., Gomeni, R., Ratti, E., Cunningham, V.J.
A pharmacokinetic PET study of NK1 receptor occupancy
(2012) European Journal of Nuclear Medicine and Molecular Imaging, 39 (2), pp. 226-235. Cited 9 times.
Document Type: Article
Source: Scopus
Shotbolt, P., Tziortzi, A.C., Searle, G.E., Colasanti, A., Van Der Aart, J., Abanades, S., Plisson, C., Miller, S.R., Huiban, M.,
Beaver, J.D., Gunn, R.N., Laruelle, M., Rabiner, E.A.
Within-subject comparison of 11C-()-PHNO and 11 Craclopride sensitivity to acute amphetamine challenge in
healthy humans
(2012) Journal of Cerebral Blood Flow and Metabolism, 32 (1), pp. 127-136. Cited 29 times.
Document Type: Article
Source: Scopus
Owen, D.R., Yeo, A.J., Gunn, R.N., Song, K., Wadsworth, G., Lewis, A., Rhodes, C., Pulford, D.J., Bennacef, I., Parker, C.A.,
Stjean, P.L., Cardon, L.R., Mooser, V.E., Matthews, P.M., Rabiner, E.A., Rubio, J.P.
An 18-kDa Translocator Protein (TSPO) polymorphism explains differences in binding affinity of the PET radioligand
PBR28
(2012) Journal of Cerebral Blood Flow and Metabolism, 32 (1), pp. 1-5. Cited 46 times.
Document Type: Article
Source: Scopus
Gunn, R.N., Murthy, V., Catafau, A.M., Searle, G., Bullich, S., Slifstein, M., Ouellet, D., Zamuner, S., Herance, R., Salinas, C.,
Pardo-Lozano, R., Rabiner, E.A., Farre, M., Laruelle, M.
Translational characterization of [11C]GSK931145, a PET ligand for the glycine transporter type 1
(2011) Synapse, 65 (12), pp. 1319-1332. Cited 12 times.
Document Type: Article
Source: Scopus
Tziortzi, A., Searle, G., Tsoumpas, C., Long, C., Shotbolt, P., Rabiner, E., Jenkinson, M., Gunn, R.N.
MR-DTI and PET multimodal imaging of dopamine release within subdivisions of basal ganglia
(2011) Journal of Physics: Conference Series, 317 (1), art. no. 012005, . Cited 2 times.
Document Type: Conference Paper
Source: Scopus
Ridler, K., Plisson, C., Rabiner, E.A., Gunn, R.N., Easwaramoorthy, B., Abi-Dargham, A., Laruelle, M., Slifstein, M.
Characterization of in vivo pharmacological properties and sensitivity to endogenous serotonin of [ 11C] P943: A
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positron emission tomography study in Papio anubis


(2011) Synapse, 65 (11), pp. 1119-1127. Cited 7 times.
Document Type: Article
Source: Scopus
Matthews, P.M., Rabiner, I., Gunn, R.
Non-invasive imaging in experimental medicine for drug development
(2011) Current Opinion in Pharmacology, 11 (5), pp. 501-507. Cited 14 times.
Document Type: Article
Source: Scopus
Bullich, S., Slifstein, M., Passchier, J., Murthy, N.V., Kegeles, L.S., Kim, J.-H., Xu, X., Gunn, R.N., Herance, R., Gispert, J.D.,
Gutirrez, A., Farr, M., Laruelle, M., Catafau, A.M.
Biodistribution and radiation dosimetry of the glycine transporter-1 ligand 11C-GSK931145 determined from primate
and human whole-body PET
(2011) Molecular Imaging and Biology, 13 (4), pp. 776-784. Cited 6 times.
Document Type: Article
Source: Scopus
Rabiner, E.A., Beaver, J., Makwana, A., Searle, G., Long, C., Nathan, P.J., Newbould, R.D., Howard, J., Miller, S.R., Bush,
M.A., Hill, S., Reiley, R., Passchier, J., Gunn, R.N., Matthews, P.M., Bullmore, E.T.
Pharmacological differentiation of opioid receptor antagonists by molecular and functional imaging of target
occupancy and food reward-related brain activation in humans
(2011) Molecular Psychiatry, 16 (8), pp. 826-835. Cited 29 times.
Document Type: Article
Source: Scopus
Plisson, C., Salinas, C., Weinzimmer, D., Labaree, D., Lin, S.-F., Ding, Y.-S., Jakobsen, S., Smith, P.W., Eiji, K., Carson, R.E.,
Gunn, R.N., Rabiner, E.A.
Radiosynthesis and in vivo evaluation of [ 11C]MP-10 as a positron emission tomography radioligand for
phosphodiesterase 10A
(2011) Nuclear Medicine and Biology, 38 (6), pp. 875-884. Cited 15 times.
Document Type: Article
Source: Scopus
Gunn, R.N., Guo, Q., Salinas, C.A., Tziortzi, A.C., Searle, G.E.
Advances in biomathematical modeling for PET neuroreceptor imaging
(2011) Drug Discovery Today: Technologies, 8 (2-4), pp. e45-e51.
Document Type: Review
Source: Scopus
Girgis, R.R., Xu, X., Miyake, N., Easwaramoorthy, B., Gunn, R.N., Rabiner, E.A., Abi-Dargham, A., Slifstein, M.
In vivo binding of antipsychotics to D 3 and D 2 receptors: A PET study in baboons with [ 11C]-( + )-PHNO
(2011) Neuropsychopharmacology, 36 (4), pp. 887-895. Cited 11 times.
Document Type: Article
Source: Scopus
Abanades, S., Van Der Aart, J., Barletta, J.A.R., Marzano, C., Searle, G.E., Salinas, C.A., Ahmad, J.J., Reiley, R.R.,
Pampols-Maso, S., Zamuner, S., Cunningham, V.J., Rabiner, E.A., Laruelle, M.A., Gunn, R.N.
Prediction of repeat-dose occupancy from single-dose data: Characterisation of the relationship between plasma
pharmacokinetics and brain target occupancy
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(2011) Journal of Cerebral Blood Flow and Metabolism, 31 (3), pp. 944-952. Cited 22 times.
Document Type: Article
Source: Scopus
Pike, V.W., Taliani, S., Lohith, T.G., Owen, D.R.J., Pugliesi, I., Da Pozzo, E., Hong, J., Zoghbi, S.S., Gunn, R.N., Parker,
C.A., Rabiner, E.A., Fujita, M., Innis, R.B., Martini, C., Da Settimo, F.
Evaluation of novel N 1-methyl-2-phenylindol-3-ylglyoxylamides as a new chemotype of 18 kDa translocator proteinselective ligand suitable for the development of positron emission tomography radioligands
(2011) Journal of Medicinal Chemistry, 54 (1), pp. 366-373. Cited 7 times.
Document Type: Article
Source: Scopus
Tziortzi, A.C., Searle, G.E., Tzimopoulou, S., Salinas, C., Beaver, J.D., Jenkinson, M., Laruelle, M., Rabiner, E.A., Gunn,
R.N.
Imaging dopamine receptors in humans with [11C]-(+)-PHNO: Dissection of D3 signal and anatomy
(2011) NeuroImage, 54 (1), pp. 264-277. Cited 66 times.
Document Type: Article
Source: Scopus
Owen, D.R.J., Gunn, R.N., Rabiner, E.A., Bennacef, I., Fujita, M., Kreisl, W.C., Innis, R.B., Pike, V.W., Reynolds, R.,
Matthews, P.M., Parker, C.A.
Mixed-affinity binding in humans with 18-kDa translocator protein ligands
(2011) Journal of Nuclear Medicine, 52 (1), pp. 24-32. Cited 65 times.
Document Type: Article
Source: Scopus
Owen, D.R., Howell, O.W., Tang, S.-P., Wells, L.A., Bennacef, I., Bergstrom, M., Gunn, R.N., Rabiner, E.A., Wilkins, M.R.,
Reynolds, R., Matthews, P.M., Parker, C.A.
Two binding sites for 3 HPBR28 in human brain: Implications for TSPO PET imaging of neuroinflammation
(2010) Journal of Cerebral Blood Flow and Metabolism, 30 (9), pp. 1608-1618. Cited 47 times.
Document Type: Article
Source: Scopus
Devanand, D.P., Mikhno, A., Pelton, G.H., Cuasay, K., Pradhaban, G., Dileep Kumar, J.S., Upton, N., Lai, R., Gunn, R.N.,
Libri, V., Xinhua Liu, Van Heertum, R., Mann, J.J., Parsey, R.V.
Pittsburgh compound B (11C-PIB) and fluorodeoxyglucose (18 F-FDG) PET in patients with Alzheimer disease, mild
cognitive impairment, and healthy controls
(2010) Journal of Geriatric Psychiatry and Neurology, 23 (3), pp. 185-198. Cited 49 times.
Document Type: Article
Source: Scopus
Searle, G., Beaver, J.D., Comley, R.A., Bani, M., Tziortzi, A., Slifstein, M., Mugnaini, M., Griffante, C., Wilson, A.A., MerloPich, E., Houle, S., Gunn, R., Rabiner, E.A., Laruelle, M.
Imaging dopamine D3 receptors in the human brain with positron emission tomography, [11C]PHNO, and a selective
D3 receptor antagonist
(2010) Biological Psychiatry, 68 (4), pp. 392-399. Cited 59 times.
Document Type: Article
Source: Scopus
Ashworth, S., Rabiner, E.A., Gunn, R.N., Plisson, C., Wilson, A.A., Comley, R.A., Lai, R.Y.K., Gee, A.D., Laruelle, M.,
Cunningham, V.J.
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Evaluation of11C-GSK189254 as a novel radioligand for the H 3 receptor in humans using PET
(2010) Journal of Nuclear Medicine, 51 (7), pp. 1021-1029. Cited 27 times.
Document Type: Article
Source: Scopus
Xie, J., Clare, S., Gallichan, D., Gunn, R.N., Jezzard, P.
Real-time adaptive sequential design for optimal acquisition of arterial spin labeling MRI data
(2010) Magnetic Resonance in Medicine, 64 (1), pp. 203-210. Cited 6 times.
Document Type: Article
Source: Scopus
Passchier, J., Gentile, G., Porter, R., Herdon, H., Salinas, C., Jakobsen, S., Audrain, H., Laruelle, M., Gunn, R.N.
Identification and evaluation of [11C]GSK931145 as a novel ligand for imaging the type 1 glycine transporter with
positron emission tomography
(2010) Synapse, 64 (7), pp. 542-549. Cited 21 times.
Document Type: Article
Source: Scopus
Catafau, A.M., Searle, G.E., Bullich, S., Gunn, R.N., Rabiner, E.A., Herance, R., Radua, J., Farre, M., Laruelle, M.
Imaging cortical dopamine D1 receptors using [ 11C]NNC112 and ketanserin blockade of the 5-HT2A receptors
(2010) Journal of Cerebral Blood Flow and Metabolism, 30 (5), pp. 985-993. Cited 6 times.
Document Type: Article
Source: Scopus
Bullich, S., Cot, A., Gallego, J., Gunn, R.N., Surez, M., Pava, J., Ros, D., Laruelle, M., Catafau, A.M.
Impact of scatter correction on D2 receptor occupancy measurements using 123I-IBZM SPECT: Comparison to 11CRaclopride PET
(2010) NeuroImage, 50 (4), pp. 1511-1518. Cited 8 times.
Document Type: Article
Source: Scopus
Zamuner, S., Di Iorio, V.L., Nyberg, J., Gunn, R.N., Cunningham, V.J., Gomeni, R., Hooker, A.C.
Adaptive-optimal design in PET occupancy studies
(2010) Clinical Pharmacology and Therapeutics, 87 (5), pp. 563-571. Cited 14 times.
Document Type: Article
Source: Scopus
Cunningham, V.J., Rabiner, E.A., Slifstein, M., Laruelle, M., Gunn, R.N.
Measuring drug occupancy in the absence of a reference region: The Lassen plot re-visited
(2010) Journal of Cerebral Blood Flow and Metabolism, 30 (1), pp. 46-50. Cited 61 times.
Document Type: Article
Source: Scopus
Plisson, C., Gunn, R.N., Cunningham, V.J., Bender, D., Salinas, C.A., Medhurst, A.D., Roberts, J.C., Laruelle, M., Gee, A.D.
11C-GSK189254: A selective radioligand for in vivo central nervous system imaging of histamine H3 receptors by
PET
(2009) Journal of Nuclear Medicine, 50 (12), pp. 2064-2072. Cited 19 times.
Document Type: Article
Source: Scopus

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Guo, Q., Brady, M., Gunn, R.N.


A biomathematical modeling approach to central nervous system radioligand discovery and development
(2009) Journal of Nuclear Medicine, 50 (10), pp. 1715-1723. Cited 36 times.
Document Type: Article
Source: Scopus
Rabiner, E.A., Slifstein, M., Nobrega, J., Plisson, C., Huiban, M., Raymond, R., Diwan, M., Wilson, A.A., McCormick, P.,
Gentile, G., Gunn, R.N., Laruelle, M.A.
In vivo quantification of regional dopamine-D3 receptor binding potential of (+)-PHNO: Studies in non-human
primates and transgenic mice
(2009) Synapse, 63 (9), pp. 782-793. Cited 64 times.
Document Type: Article
Source: Scopus
Bennacef, I., Salinas, C.A., Bonasera, T.A., Gunn, R.N., Audrain, H., Jakobsen, S., Nabulsi, N., Weinzimmer, D., Carson,
R.E., Huang, Y., Holmes, I., Micheli, F., Heidbreder, C., Gentile, G., Rossi, T., Laruelle, M.
Dopamine D3 receptor antagonists: The quest for a potentially selective PET ligand. Part 3: Radiosynthesis and in
vivo studies
(2009) Bioorganic and Medicinal Chemistry Letters, 19 (17), pp. 5056-5059. Cited 12 times.
Document Type: Article
Source: Scopus
Marner, L., Gillings, N., Comley, R.A., Baar, W.F.C., Rabiner, E.A., Wilson, A.A., Houle, S., Hasselbalch, S.G., Svarer, C.,
Gunn, R.N., Laruelle, M., Knudsen, G.M.
Kinetic modeling of11C-SB207145 binding to 5-HT4 receptors in the human brain in vivo
(2009) Journal of Nuclear Medicine, 50 (6), pp. 900-908. Cited 30 times.
Document Type: Article
Source: Scopus
Catafau, A.M., Suarez, M., Bullich, S., Llop, J., Nucci, G., Gunn, R.N., Brittain, C., Laruelle, M.
Within-subject comparison of striatal D2 receptor occupancy measurements using [123I]IBZM SPECT and
[11C]Raclopride PET
(2009) NeuroImage, 46 (2), pp. 447-458. Cited 20 times.
Document Type: Article
Source: Scopus
Narendran, R., Frankle, W.G., Mason, N.S., Rabiner, E.A., Gunn, R.N., Searle, G.E., Vora, S., Litschge, M., Kendro, S.,
Cooper, T.B., Mathis, C.A., Laruelle, M.
Positron emission tomography imaging of amphetamine-induced dopamine release in the human cortex: A
comparative evaluation of the high affinity dopamine D2/3 radiotracers [11C]FLB 457 and [ 11C]fallypride
(2009) Synapse, 63 (6), pp. 447-461. Cited 46 times.
Document Type: Article
Source: Scopus
Summerfield, S.G., Lucas, A.J., Porter, R.A., Jeffrey, P., Gunn, R.N., Read, K.R., Stevens, A.J., Metcalf, A.C., Osuna, M.C.,
Kilford, P.J., Passchier, J., Ruffo, A.D.
Toward an improved prediction of human in vivo brain penetration
(2008) Xenobiotica, 38 (12), pp. 1518-1535. Cited 37 times.
Document Type: Article
Source: Scopus

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Peng, J.-Y., Aston, J.A.D., Gunn, R.N., Liou, C.-Y., Ashburner, J.


Dynamic positron emission tomography data-driven analysis using sparse Bayesian learning
(2008) IEEE Transactions on Medical Imaging, 27 (9), art. no. 4573270, pp. 1356-1369. Cited 9 times.
Document Type: Article
Source: Scopus
Mikhno, A., Devanand, D., Pelton, G., Cuasay, K., Gunn, R., Upton, N., Lai, R.Y., Libri, V., Mann, J.J., Parsey, R.V.
Voxel-based analysis of11C-PIB scans for diagnosing Alzheimer's disease
(2008) Journal of Nuclear Medicine, 49 (8), pp. 1262-1269. Cited 24 times.
Document Type: Article
Source: Scopus
Xie, J., Gallichan, D., Gunn, R.N., Jezzard, P.
Optimal design of pulsed arterial spin labeling MRI experiments
(2008) Magnetic Resonance in Medicine, 59 (4), pp. 826-834. Cited 20 times.
Document Type: Article
Source: Scopus
Cunningham, V.J., Gunn, R.N., Rabiner, E., Slifstein, M., Laruelle, M.
Graphical analysis of occupancy studies
(2007) Journal of Cerebral Blood Flow and Metabolism, 27 (SUPPL. 1), pp. PS01-04M. Cited 1 time.
Document Type: Conference Paper
Source: Scopus
Marner, L., Gillings, N., Gunn, R.N., Comley, R., Baare, W., Hasselbalch, S.G., Knudsen, G.M.
Quantification of 11C-SB207145-PET for 5-HT4 receptors in the human brain: Preliminary results
(2007) Journal of Cerebral Blood Flow and Metabolism, 27 (SUPPL. 1), pp. PP04-07M.
Document Type: Conference Paper
Source: Scopus
Gunn, R., Summerfield, S., Salinas, C., Read, K., Searle, G., Ruffo, A., Parker, C., Stevens, A., Bonasera, T., Jeffrey, P.,
Laruelle, M.
Combining PET and equilibrium dialysis to assess blood brain barrier transport
(2007) Journal of Cerebral Blood Flow and Metabolism, 27 (SUPPL. 1), pp. PO04-01U. Cited 4 times.
Document Type: Conference Paper
Source: Scopus
Innis, R.B., Cunningham, V.J., Delforge, J., Fujita, M., Gjedde, A., Gunn, R.N., Holden, J., Houle, S., Huang, S.-C., Ichise,
M., Iida, H., Ito, H., Kimura, Y., Koeppe, R.A., Knudsen, G.M., Knuuti, J., Lammertsma, A.A., Laruelle, M., Logan, J.,
Maguire, R.P., Mintun, M.A., Morris, E.D., Parsey, R., Price, J.C., Slifstein, M., Sossi, V., Suhara, T., Votaw, J.R., Wong, D.F.,
Carson, R.E.
Consensus nomenclature for in vivo imaging of reversibly binding radioligands
(2007) Journal of Cerebral Blood Flow and Metabolism, 27 (9), pp. 1533-1539. Cited 697 times.
Document Type: Review
Source: Scopus
Boileau, I., Dagher, A., Leyton, M., Gunn, R.N., Baker, G.B., Diksic, M., Benkelfat, C.
Modeling sensitization to stimulants in humans: An [11C] raclopride/positron emission tomography study in healthy
men
(2006) Archives of General Psychiatry, 63 (12), pp. 1386-1395. Cited 148 times.
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Source: Scopus
Cunningham, V.J., Gunn, R.N.
Positron emission tomography - Tracer kinetic modelling in drug development
(2006) Astroparticle, Particle and Space Physics, Detectors and Medical Physics Applications - Proceedings of the 9th
Conference, pp. 697-704.
Document Type: Conference Paper
Source: Scopus
Frankle, W.G., Slifstein, M., Gunn, R.N., Huang, Y., Hwang, D.-R., Darr, E.A., Narendran, R., Abi-Dargham, A., Laruelle, M.
Estimation of serotonin transporter parameters with11C-DASB in healthy humans: Reproducibility and comparison
of methods
(2006) Journal of Nuclear Medicine, 47 (5), pp. 815-826. Cited 49 times.
Document Type: Article
Source: Scopus
Cunningham, V.J., Parker, C.A., Rabiner, E.A., Gee, A.D., Gunn, R.N., Lammertsma, A.A.
PET studies in drug development: Methodological considerations
(2005) Drug Discovery Today: Technologies, 2 (4), pp. 311-315. Cited 21 times.
Document Type: Review
Source: Scopus
Wells, P., Gunn, R.N., Steel, C., Ranicar, A.S., Brady, F., Osman, S., Jones, T., Price, P.
2-[11C]thymidine positron emission tomography reproducibility in humans
(2005) Clinical Cancer Research, 11 (12), pp. 4341-4347. Cited 9 times.
Document Type: Article
Source: Scopus
Aston, J.A.D., Gunn, R.N.
Statistical estimation with Kronecker products in positron emission tomography
(2005) Linear Algebra and Its Applications, 398 (1-3), pp. 25-36. Cited 2 times.
Document Type: Article
Source: Scopus
Parker, C.A., Matthews, J.C., Gunn, R.N., Martarello, L., Cunningham, V.J., Dommett, D., Knibb, S.T., Bender, D., Jakobsen,
S., Brown, J., Gee, A.D.
Behaviour of [11C]R(-)- and [11C]S(+)-rolipram in vitro and in vivo, and their use as PET radiotracers for the
quantificative assay of PDE4
(2005) Synapse, 55 (4), pp. 270-279. Cited 24 times.
Document Type: Article
Source: Scopus
Bnar, C.-G., Gunn, R.N., Grova, C., Champagne, B., Gotman, J.
Statistical maps for EEG dipolar source localization
(2005) IEEE Transactions on Biomedical Engineering, 52 (3), pp. 401-413. Cited 12 times.
Document Type: Article
Source: Scopus

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Aston, J.A.D., Gunn, R.N., Hinz, R., Turkheimer, F.E.


Wavelet variance components in image space for spatiotemporal neuroimaging data
(2005) NeuroImage, 25 (1), pp. 159-168. Cited 12 times.
Document Type: Article
Source: Scopus
Rabiner, E.A., Bhagwagar, Z., Gunn, R.N., Cowen, P.J., Grasby, P.M.
Preferential 5-HT1A autoreceptor occupancy by pindolol is attenuated in depressed patients: Effect of treatment or
an endophenotype of depression?
(2004) Neuropsychopharmacology, 29 (9), pp. 1688-1698. Cited 28 times.
Document Type: Article
Source: Scopus
Cunningham, V.J., Gunn, R.N., Matthews, J.C.
Quantification in positron emission tomography for research in pharmacology and drug development
(2004) Nuclear Medicine Communications, 25 (7), pp. 643-646. Cited 25 times.
Document Type: Conference Paper
Source: Scopus
Zald, D.H., Boileau, I., El-Dearedy, W., Gunn, R., McGlone, F., Dichter, G.S., Dagher, A.
Dopamine Transmission in the Human Striatum during Monetary Reward Tasks
(2004) Journal of Neuroscience, 24 (17), pp. 4105-4112. Cited 127 times.
Document Type: Article
Source: Scopus
Asselin, M.-C., Cunningham, V.J., Amano, S., Gunn, R.N., Nahmias, C.
Parametrically defined cerebral blood vessels as non-invasive blood input functions for brain PET studies
(2004) Physics in Medicine and Biology, 49 (6), pp. 1033-1054. Cited 13 times.
Document Type: Article
Source: Scopus
Kukreja, S.L., Gunn, R.N.
Bootstrapped DEPICT for error estimation in PET functional imaging
(2004) NeuroImage, 21 (3), pp. 1096-1104. Cited 9 times.
Document Type: Article
Source: Scopus
Leyton, M., Dagher, A., Boileau, I., Casey, K., Baker, G.B., Diksic, M., Gunn, R., Young, S.N., Benkelfat, C.
Decreasing Amphetamine-Induced Dopamine Release by Acute Phenylalanine/Tyrosine Depletion: A
PET/[11C]Raclopride Study in Healthy Men
(2004) Neuropsychopharmacology, 29 (2), pp. 427-432. Cited 49 times.
Document Type: Article
Source: Scopus
Xie, G., Gunn, R.N., Dagher, A., Daloze, T., Plourde, G., Backman, S.B., Diksic, M., Fiset, P.
PET Quantification of Muscarinic Cholinergic Receptors with [N- 11C-methyl]-Benztropine and Application to
Studies of Propofol-Induced Unconsciousness in Healthy Human Volunteers
(2004) Synapse, 51 (2), pp. 91-101. Cited 9 times.
Document Type: Article
Source: Scopus
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Reilhac, A., Lartizien, C., Costes, N., Sans, S., Comtat, C., Gunn, R.N., Evans, A.C.
PET-SORTEO: A Monte Carlo-based simulator with high count rate capabilities
(2004) IEEE Transactions on Nuclear Science, 51 (1 I), pp. 46-52. Cited 71 times.
Document Type: Article
Source: Scopus
Bressan, R.A., Erlandsson, K., Mulligan, R.S., Gunn, R.N., Cunningham, V.J., Owens, J., Cullum, I.D., Ell, P.J., Pilowsky,
L.S.
A bolus/infusion paradigm for the novel NMDA receptor SPET tracer [ 123i]CNS 1261
(2004) Nuclear Medicine and Biology, 31 (2), pp. 155-164. Cited 13 times.
Document Type: Article
Source: Scopus
Turkheimer, F.E., Hinz, R., Gunn, R.N., Aston, J.A.D., Gunn, S.R., Cunningham, V.J.
Rank-shaping regularization of exponential spectral analysis for application to functional parametric mapping
(2003) Physics in Medicine and Biology, 48 (23), pp. 3819-3841. Cited 22 times.
Document Type: Article
Source: Scopus
Aston, J., Turkheimer, F., Cunningham, V., Gunn, R.
Wavelet Variance Components in Image Space for Spatio-Temporal Neuroimaging Data
(2003) Proceedings of SPIE - The International Society for Optical Engineering, 5207 (2), pp. 849-857. Cited 1 time.
Document Type: Conference Paper
Source: Scopus
Bressan, R.A., Erlandsson, K., Mulligan, R.S., Gunn, R.N., Cunningham, V.J., Owens, J., Ell, P.J., Pilowsky, L.S.
Evaluation of NMDA Receptors in Vivo in Schizophrenic Patients with [ 123I]CNS 1261 and SPET: Preliminary
Findings
(2003) Annals of the New York Academy of Sciences, 1003, pp. 364-367. Cited 10 times.
Document Type: Conference Paper
Source: Scopus
Gerhard, A., Banati, R.B., Goerres, G.B., Cagnin, A., Myers, R., Gunn, R.N., Turkheimer, F., Good, C.D., Mathias, C.J.,
Quinn, N., Schwarz, J., Brooks, D.J.
[11C](R)-PK11195 PET imaging of microglial activation in multiple system atrophy
(2003) Neurology, 61 (5), pp. 686-689. Cited 95 times.
Document Type: Article
Source: Scopus
Wells, P., Aboagye, E., Gunn, R.N., Osman, S., Boddy, A.V., Taylor, G.A., Rafi, I., Hughes, A.N., Calvert, A.H., Price, P.M.,
Newell, D.R.
2-[11C]thymidine positron emission tomography as an indicator of thymidylate synthase inhibition in patients
treated with AG337
(2003) Journal of the National Cancer Institute, 95 (9), pp. 675-682. Cited 36 times.
Document Type: Article
Source: Scopus
Erlandsson, K., Bressan, R.A., Mulligan, R.S., Gunn, R.N., Cunningham, V.J., Owens, J., Wyper, D., Ell, P.J., Pilowsky, L.S.
Kinetic modelling of [123I]CNS 1261 - A potential SPET tracer for the NMDA receptor
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(2003) Nuclear Medicine and Biology, 30 (4), pp. 441-454. Cited 25 times.
Document Type: Article
Source: Scopus
Gunn, R.N., Gunn, S.R., Turkheimer, F.E., Aston, J.A.D., Cunningham, V.J.
Positron emission tomography compartmental models: A basis pursuit strategy for kinetic modeling
(2002) Journal of Cerebral Blood Flow and Metabolism, 22 (12), pp. 1425-1439. Cited 89 times.
Document Type: Article
Source: Scopus
Sechet, S., Reilhac, A., Gunn, R., Evans, A., Dagher, A.
Frame misalignement-induced errors in PET studies: An investigation on strategies for correction
(2002) IEEE Nuclear Science Symposium and Medical Imaging Conference, 2, pp. 1330-1334. Cited 1 time.
Document Type: Conference Paper
Source: Scopus
Wells, P., Gunn, R.N., Alison, M., Steel, C., Golding, M., Ranicar, A.S., Brady, F., Osman, S., Jones, T., Price, P.
Assessment of proliferation in vivo using 2-[11C]thymidine positron emission tomography in advanced intraabdominal malignancies
(2002) Cancer Research, 62 (20), pp. 5698-5702. Cited 53 times.
Document Type: Article
Source: Scopus
Rabiner, E., Gunn, R.N., Wilkins, M.R., Sedman, E., Grasby, P.
Evaluation of EMD 128 130 occupancy of the 5-HT1A and the D2 receptor: A human PET study with [11C]WAY100635 and [11C]raclopride
(2002) Journal of Psychopharmacology, 16 (3), pp. 195-199. Cited 28 times.
Document Type: Article
Source: Scopus
Rabiner, E.A., Messa, C., Sargent, P.A., Husted-Kjaer, K., Montgomery, A., Lawrence, A.D., Bench, C.J., Gunn, R.N.,
Cowen, P., Grasby, P.M.
A database of [11C]WAY-100635 binding to 5-HT1A receptors in normal male volunteers: Normative data and
relationship to methodological, demographic, physiological, and behavioral variables
(2002) NeuroImage, 15 (3), pp. 620-632. Cited 95 times.
Document Type: Article
Source: Scopus
Aston, J.A.D., Cunningham, V.J., Asselin, M.-C., Hammers, A., Evans, A.C., Gunn, R.N.
Positron emission tomography partial volume correction: Estimation and algorithms
(2002) Journal of Cerebral Blood Flow and Metabolism, 22 (8), pp. 1019-1034. Cited 103 times.
Document Type: Article
Source: Scopus
Rabiner, E.A., Wilkins, M.R., Turkheimer, F., Gunn, R.N., De Haes, J.U., De Vries, M., Grasby, P.M.
5-Hydroxytryptamine1A receptor occupancy by novel full antagonist 2-[4-[4-(7-Chloro-2,3-dihydro-1,4-benzdioxyn-5yl)-1-piperazinyl]butyl] -1,2-benzisothiazol-3-(2H)-one-1,1-dioxide: A [11C][O-methyl-3H]-N-(2-(4-(2methoxyphenyl)-1-piperazinyl) ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide trihydrochloride (WAY-100635)
positron emission tomography study in humans
(2002) Journal of Pharmacology and Experimental Therapeutics, 301 (3), pp. 1144-1150. Cited 33 times.

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Source: Scopus
Andre, B., Halldin, C., Pike, V.W., Gunn, R.N., Olsson, H., Farde, L.
The PET radioligand [carbonyl-11C]desmethyl-WAY-100635 binds to 5-HT1A receptors and provides a higher
radioactive signal than [carbonyl-11C]WAY-100635 in the human brain
(2002) Journal of Nuclear Medicine, 43 (3), pp. 292-303. Cited 28 times.
Document Type: Article
Source: Scopus
Rabiner, E.A., Bhagwagar, Z., Gunn, R.N., Sargent, P.A., Bench, C.J., Cowen, P.J., Grasby, P.M.
Pindolol augmentation of selective serotonin reuptake inhibitors: PET evidence that the dose used in clinical trials
is too low
(2001) American Journal of Psychiatry, 158 (12), pp. 2080-2082. Cited 65 times.
Document Type: Article
Source: Scopus
Banati, R.B., Cagnin, A., Brooks, D.J., Gunn, R.N., Myers, R., Jones, T., Birch, R., Anand, P.
Long-term trans-synaptic glial responses in the human thalamus after peripheral nerve injury
(2001) NeuroReport, 12 (16), pp. 3439-3442. Cited 52 times.
Document Type: Article
Source: Scopus
Montgomery, A.J., Bench, C.J., Young, A.H., Hammers, A., Gunn, R.N., Bhagwagar, Z., Grasby, P.M.
PET measurement of the influence of corticosteroids on serotonin-1A receptor number
(2001) Biological Psychiatry, 50 (9), pp. 668-676. Cited 20 times.
Document Type: Article
Source: Scopus
Cagnin, A., Myers, R., Gunn, R.N., Lawrence, A.D., Stevens, T., Kreutzberg, G.W., Jones, T., Banati, R.B.
In vivo visualization of activated glia by [11C] (R)-PK11195-PET following herpes encephalitis reveals projected
neuronal damage beyond the primary focal lesion
(2001) Brain, 124 (10), pp. 2014-2027. Cited 111 times.
Document Type: Article
Source: Scopus
Dagher, A., Bleicher, C., Aston, J.A.D., Gunn, R.N., Clarke, P.B.S., Cumming, P.
Reduced dopamine D1 receptor binding in the ventral striatum of cigarette smokers
(2001) Synapse, 42 (1), pp. 48-53. Cited 74 times.
Document Type: Article
Source: Scopus
Cagnin, A., Brooks, D.J., Kennedy, A.M., Gunn, R.N., Myers, R., Turkheimer, F.E., Jones, T., Banati, R.B.
In-vivo measurement of activated microglia in dementia
(2001) Lancet, 358 (9280), pp. 461-467. Cited 507 times.
Document Type: Article
Source: Scopus
Gunn, R.N., Gunn, S.R., Cunningham, V.J.
Positron emission tomography compartmental models
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(2001) Journal of Cerebral Blood Flow and Metabolism, 21 (6), pp. 635-652. Cited 155 times.
Document Type: Article
Source: Scopus
Price, J.C., Lopresti, B.J., Meltzer, C.C., Smith, G.S., Mason, N.S., Huang, Y., Holt, D.P., Gunn, R.N., Mathis, C.A.
Analyses of [18F]altanserin bolus injection PET data. II: Consideration of radiolabeled metabolites in humans
(2001) Synapse, 41 (1), pp. 11-21. Cited 35 times.
Document Type: Article
Source: Scopus
Banati, R.B., Cagnin, A., Myers, R., Gunn, R.N., Turkheimer, F.E., Brooks, D.J., Jones, T.
Microglial activation in neurodegenerative diseases: A PET study using [11C](R)-PK11195
(2000) NeuroImage, 11 (6 PART II), .
Document Type: Article
Source: Scopus
Koepp, M.J., Gunn, R.N., Grasby, P.M., Bloomfield, P., Cunningham, V.J.
Changes in cerebral blood flow during a videogame: A quantitative H2 15O-PET study
(2000) NeuroImage, 11 (6 PART II), . Cited 2 times.
Document Type: Article
Source: Scopus
Aston, J.A.D., Asselin, M.-C., Gunn, R.N., Cunningham, V.J.
Estimation of errors in partial volume correction
(2000) NeuroImage, 11 (6 PART II), .
Document Type: Article
Source: Scopus
Aston, J., Worsley, K.J., Turkheimer, F.E., Cunningham, V.J., Gunn, R.N.
A bayesian approach to spectral analysis
(2000) NeuroImage, 11 (6 PART II), .
Document Type: Article
Source: Scopus
Banati, R.B., Newcombe, J., Gunn, R.N., Cagnin, A., Turkheimer, F., Heppner, F., Price, G., Wegner, F., Giovannoni, G.,
Miller, D.H., Perkin, G.D., Smith, T., Hewson, A.K., Bydder, G., Kreutzberg, G.W., Jones, T., Cuzner, M.L., Myers, R.
The peripheral benzodiazepine binding site in the brain in multiple sclerosis. Quantitative in vivo imaging of
microglia as a measure of disease activity
(2000) Brain, 123 (11), pp. 2321-2337. Cited 328 times.
Document Type: Article
Source: Scopus
Pappata, S., Levasseur, M., Gunn, R.N., Myers, R., Crouzel, C., Syrota, A., Jones, T., Kreutzberg, G.W., Banati, R.B.
Thalamic microglial activation in ischemic stroke detected in vivo by PET and [(11)C]PK11195
(2000) Neurology, 55 (7), pp. 1052-1054. Cited 137 times.
Document Type: Article
Source: Scopus
Aston, J.A.D., Gunn, R.N., Worsley, K.J., Ma, Y., Evans, A.C., Dagher, A.
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A statistical method for the analysis of positron emission tomography neuroreceptor ligand data
(2000) NeuroImage, 12 (3), pp. 245-256. Cited 62 times.
Document Type: Article
Source: Scopus
Rabiner, E.A., Gunn, R.N., Castro, M.E., Sargent, P.A., Cowen, P.J., Koepp, M.J., Meyer, J.H., Bench, C.J., Harrison, P.J.,
Pazos, A., Sharp, T., Grasby, P.M.
-blocker binding to human 5-HT(1A) receptors in vivo and in vitroImplications for antidepressant therapy
(2000) Neuropsychopharmacology, 23 (3), pp. 285-293. Cited 64 times.
Document Type: Article
Source: Scopus
Gunn, R.N., Lammertsma, A.A., Grasby, P.M.
Quantitative analysis of [carbonyl-11C]WAY-100635 PET studies
(2000) Nuclear Medicine and Biology, 27 (5), pp. 477-482. Cited 37 times.
Document Type: Article
Source: Scopus
Rabiner, E.A., Gunn, R.N., Wilkins, M.R., Sargent, P.A., Mocaer, E., Sedman, E., Cowen, P.J., Grasby, P.M.
Drug action at the 5-HT(1A) receptor in vivo: Autoreceptor and postsynaptic receptor occupancy examined with PET
and [carbonyl-11C]WAY- 100635
(2000) Nuclear Medicine and Biology, 27 (5), pp. 509-513. Cited 51 times.
Document Type: Article
Source: Scopus
Hirani, E., Opacka-Juffry, J., Gunn, R., Khan, I., Sharp, T., Hume, S.
Pindolol occupancy of 5-HT(1A) receptors measured in vivo using small animal positron emission tomography with
carbon-11 labeled WAY 100635
(2000) Synapse, 36 (4), pp. 330-341. Cited 39 times.
Document Type: Article
Source: Scopus
Turkheimer, F.E., Banati, R.B., Visvikis, D., Aston, J.A.D., Gunn, R.N., Cunningham, V.J.
Modeling dynamic PET-SPECT studies in the wavelet domain
(2000) Journal of Cerebral Blood Flow and Metabolism, 20 (5), pp. 879-893. Cited 40 times.
Document Type: Article
Source: Scopus
Hume, S.P., Hirani, E., Opacka-Juffry, J., Osman, S., Myers, R., Gunn, R.N., McCarron, J.A., Clark, R.D., Melichar, J., Nutt,
D.J., Pike, V.W.
Evaluation of [O-methyl-11C]RS.15385-197 as a positron emission tomography radioligand for central 2adrenoceptors
(2000) European Journal of Nuclear Medicine, 27 (5), pp. 475-484. Cited 12 times.
Document Type: Article
Source: Scopus
Gunn, R.N., Ranicar, A., Yap, J.T., Wells, P., Osman, S., Jones, T., Cunningham, V.J.
On-line measurement of exhaled [11C]CO2 during PET
(2000) Journal of Nuclear Medicine, 41 (4), pp. 605-611. Cited 13 times.
Document Type: Article
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A general method to correct PET data for tissue metabolites using a dual-scan approach
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Brain serotonin(1A) receptor binding measured by positron emission tomography with [11C]WAY-100635: Effects of
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[11C] (R)-PK11195 positron emission tomography imaging of activated microglia in vivo in Rasmussen's
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Novelty seeking behaviour correlates with dopamine D2 receptor binding in the nucleus accumbens
(1999) NeuroImage, 9 (6 PART II), .
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Dopamine release from nigral transplants visualized in vivo in a Parkinson's patient
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Huntington's disease progression. PET and clinical observations
(1999) Brain, 122 (12), pp. 2353-2363. Cited 102 times.
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Meyer, J.H., Gunn, R.N., Myers, R., Grasby, P.M.
Assessment of spatial normalization of PET ligand images using ligand- specific templates
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Steps to a neurochemistry of personality
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Evidence for dopamine release during a videogame using [11C]Raclopride PET
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Tracer kinetic modeling of the 5-HT(1A) receptor ligand [carbonyl- 11C]WAY-100635 for PET
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Evidence for striatal dopamine release during a video game
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Pharmacological constraints associated with positron emission tomographic scanning of small laboratory animals
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Characterisation of the appearance of radioactive metabolites in monkey and human plasma from the 5-HT(1A)
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Non-invasive measurement of left ventricular volumes and function by gated positron emission tomography
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