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Material Safety Data Sheet:

1. IDENTIFICATION OF THE SUBSTANCE/PREPARATION AND OF THE COMPANY/UNDERTAKING
Product name : Zydax 100 Injection & Zydax 250 Injection
Other names : PPS, PPS Injection, Pentosan, Pentosan Polysulfate, Cartrophen
Recommended use: FOR ANIMAL TREATMENT ONLY.
An aid in the treatment of non-infectious joint disease in dogs (Zydax 100) /horses (Zydax 250)
MANUFACTURER COMPANY DETAILS:
Parnell Manufacturing Pty Ltd

LICENSEE (NEW ZEALAND) DETAILS:

Parnell NZ Co

Address
Unit 4, Century Estate
476 Gardeners Road
Alexandria, NSW 2015
Australia

Address
PO Box 73160
Auckland International Airport
Manukau 2150
New Zealand

Telephone Number
61 (0)2-9667 4411

Telephone Number
0800 446 282 (Toll free within NZ)

Emergency Telephone Number

61 (0)2-9667 4411 (Business Hours)

Emergency Telephone Number

0800 446 282 (Business Hours)

Facsimile Number
Facsimile Number
61 (0)2-9667 4139
0800 727 533 (Toll free within NZ)
2. HAZARDS IDENTIFICATION
Hazardous substance according to criteria of Worksafe Australia.
3. COMPOSITION/INFORMATION ON INGREDIENTS
Chemical Entity
CAS Number
Proportion
Pentosan Polysulfate Sodium
116001-96-8
10% / 25% w/v
Antimicrobial Preservative
< 5% w/v
Buffers
< 5% w/v
Water
7732-18-5
to 100%
4. FIRST AID MEASURES
Swallowed: If poisoning occurs, contact a doctor or Poisons Information Centre.
Eye: If in eyes, hold eyes open, flood with water for at least 15 minutes. Seek medical assistance if required.
Skin: If skin contact occurs remove contaminated clothing and wash skin thoroughly with soap and water.
Inhaled: No specific requirements.
First Aid Facilities: No specific first aid facilities required.
ADVICE TO DOCTOR: Treat symptomatically as required.
5. FIRE-FIGHTING MEASURES
This material is not considered a fire hazard. Use standard fire fighting techniques to extinguish fires involving
this material. Use water spray, dry chemical, carbon dioxide or foam.
6. ACCIDENTAL RELEASE MEASURES
Clean up spilled material with absorbent ensuring no contact with skin during operation. Flush contaminated
area with water and detergent.
Dispose of waste in accordance with local, state or federal laws.
7. HANDLING AND STORAGE
Handling: Avoid contact with eyes, skin and clothing.
Storage: Store between 2C and 8C (Refrigerate. Do not freeze). Protect from light.
8. EXPOSURE CONTROLS/PERSONAL PROTECTION
Exposure Standards: No exposure standard allocated
Engineering Controls:Not applicable
Personal Protection:
Wear gloves when handling product.
Avoid spraying or splashing of the preparation.
Avoid inhalation of aerosol spray or vapour of the preparation.
Avoid eating, drinking or smoking in area of product or during handling of product.
Avoid contamination of work area.

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Material Safety Data Sheet:

9. PHYSICAL AND CHEMICAL PROPERTIES
Appearance and Odour
Clear, colourless to pale yellow solution
Boiling Point
Melting Point
Not determined
Not determined
Vapour Pressure
Specific Gravity
Not determined
Not determined
Flash Point
Flammability Limits
Not determined
Not determined
Solubility in Water
Other Properties
Soluble in water
Not applicable
10. STABILITY AND REACTIVITY
Chemical stability: Stable
Conditions to avoid: No data available
Incompatible materials: No data available
Hazardous decomposition products: No data available
Hazardous reactions: No data available
11. TOXICOLOGICAL INFORMATION
Acute Exposure:
Adverse reactions reported in humans treated with oral pentosan polysulfate include peripheral oedema,
headache, dizziness, nausea, indigestion, diarrhoea and elevation of liver function tests. Pentosan Polysulfate
has weak anticoagulant activity; transient prolongation of bleeding time is a adverse health effect.
LD50
LD50 (sodium and calcium salts)
LD50 (sodium and calcium salts)

Rat

Oral
Rat, mouse
Rat, mouse
Oral

5 g/kg
Intravenous
> 600 mg/kg
> 6 g/kg

Swallowed: May be absorbed by ingestion.

Eye: May cause transient irritation.
Skin: No health effects expected.
Inhaled: No health effects expected.
Chronic Exposure: No evidence of impaired fertility or foetal effects from daily dosing in mice, rats and rabbits.
Mutagenicity has not been demonstrated in experimental studies. No studies have been conducted on
carcinogenicity, however no carcinogenic effects have been reported.
12. ECOLOGICAL INFORMATION
No data available
13. DISPOSAL CONSIDERATIONS
Product: Observe all federal, state, and local environmental regulations.
Contaminated packaging: Dispose of as unused product.
14. TRANSPORT INFORMATION
Dangerous Goods Class and Subsidiary Risk: No class and subsidiary risk allocated
Hazchem Code: No Hazchem code allocated
Store between 2C and 8C (Refrigerate. Do not freeze). Protect from light.
15. REGULATORY INFORMATION
Poisons Schedule: Schedule 4 (Australia)
16. OTHER INFORMATION
Issue Date: 28 January 2011
Replaces MSDS dated 19 January 2010
Replaces MSDS dated 30 September 2008
Replaces MSDS dated 01 June 2006
Replaces MSDS dated 02 December 2005

End of MSDS