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1.

ATP"is ~ften described as' the 'universal


energy currency of cells; . An i.l:tiportant
feature of ATP is that it
-

4.

1n wh.ich of the following reactions


of
_photosynthesis
is the -first carbohydrate
formed?

-CA)

takes part in a lunited number of


reactionsofmetabolism
_
(B)
is uSed only where it is rriade
(C) - couples catabolic
and anabolic
_ processes.
(D)
is released ~ large amounts

2.

. When n<?n-cyciic
occurs
(A)
(B)
- _(C)
(D)

3.

. OJ) _6HJO+.6(:OJ-~CI'iH.P~+'ol
(C:)

O~H+ElQH--'H~A;U~

(0)

RlInp+(:O~ ~

photophosphorylation

-light ~nergy in the green rew.onof


. - the spectrum is absorbed
carbon dioxide is fixed oxygen is produced NAD is reduced

The products fo~ed ~t the end of stage


the
light
dependent
reactions
photosynthesiS are
-

..

s.

_.:

ZCilt.

..

The knowledge of the limiting factors which.


Tect the rate of photosyntb.esis of a particular
plant species CANNOT be used diJ:ectly to :
(A)_produce
disease resistant-plants /. (B)
increase the food yield of the plant
. (C) - - controlenvironmentalstress
- (0)
-controlfloweiing
and fruiting "

1in
of

,-

(Aj
(B)
(C)

(D)

oxygen, ATP and NADP


oxygen, ATP and reduced NADP
water, ATP and NADP
.
water, ATPand reduced NADP

02207010/SPEC2007

. -6.

'.

6lyc<;llysis reqUires gluCose, the appropriate


ailzymes and
(A) - reduced NAD
(B)
ATP
(C) - pyruvate
.
(1) - -acetyl
co-enzyme A

GO ON TO THE NEXT pAGE

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7.

The diagram
below represents
a
mitochondrion. Which of the labels I to IV
indicate the sites of Krebs Cycle and the
Electron Transport Chain?

8.

Pyruvate produced by glycolysis can only


become part of the Krebs cycle if it is first
converted to
(A)
(B)
(C)
(D)

NADH
ethanol
acetyl-coenzyme A
citrate

m-<"

Krebs.
Cycle
(A)
(B)

(C)
(D)

II
ill
IV

9.

Electron
'Ihinsporl Chain
II.
ill
IV
II

The diagram shows a simple respirometer.


l\tullD

f ".

,e-:-:: -::::-=-:.3-=-=:"':

l\fmmlnlHi'"
fluid
l'

U1~
T "\

Sod.
."

lime

~_.-Syrioge

".
{'.,ermlnatln.J&.
p~ ~

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02207010/SPEC2007

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-410.
!
,I

...

Which .ofthe fallawing is NOT a funetian.of


anaerobic respiratian itiyeast? .

13.

.Tree - caterpillars -- insectivarous birdssnakes.


,

(A)
(B)
(C)
(D)

..11..

.Which afth~ fallawing BEsT describes aD


eColagical niche? .
(A)

(B)
(C)
(D)

12.

'.

Which .ofthe fallawing diagrams represent a .


pyramid ofnumbers forthe faodchain shawn
,abave?

Generatian .ofreduced NAn


ContiJiuationaf glycolysis
Generati.on of ATP .
Productiancif carban diaxide

The relatianship between the species


and the .other organisms in the
habitat
The functionai role that the argansim
plays in its habitat .
.
The habitat thatpravides faad far the
.organism
The habitat that pravides the mast
suitable environmental conditions
. far the .organism .
.. (0)
.! ...

Whi~h .ofthe fallowing is ~nsideied as ~1ii:rrlt


t.o the number .of traphic levels in a faad
chain?
. ..
...
(A)
(B)

(C)
(D)

i
I

"

;",
,

The diversity of species in the


ecasystem
.
A high. percentage ..of the energy
cansumed is canverted ta heat
Same .ofthe energy cOnsumedis last
in faeces nd tiriJie
.
.af the.
The .. net .praductivity
ecasystem.

.
.
. .

~.

"

""

. Iten:i.14refers tathefallaWing graph which


represents biamass pf .organisms aver a '
periad .oftiine.

. ... "
~IJ

, ('

ASONb
""f(IiJIU,

14.

.-"U

.,f 1IIg;

If all faur traphic levels are represented;


which graph wauld identify plankton?
A
B

(A)
(B)

(C)
(D)

,'C
D
l.

;i

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16.

Item 15 refers to th~ following diilgram


whiclt represents part of the nitrogen cycle.

Which .of. the. following


is NOT
characteristic feature of xylem vessels?
(A)
(B)
. '(C)

(0)
17.

. (A)

15.

I'
i

(B)
(C)

.Nitrifyirig b~cteria are MOST active at .


(A)
(B)
(C)

. (0)'

No end walls. /'


Cells endto end .-/
Thick cellulose cells walls
No cell.contents (hollow)'- .
..

j ...

- -.

'f

Root pressure, ~apillarity, cohesion and


adhesion allcontribute to

NI~"I~fa
Anlmlllll

the. movement ofsuctose along


-thephloem
the ascent of water in xylem
veSSels
.
the mass flow of hutrients along .
.sieve elements
thelossofwaterviatheleaves

B
C

(O)D

Item 18 refers to the figure below showing an outline 6f soine of the cells from the phlOem
of a mango tree. .
-.

--om
18.

. Which of the following correctly identifies the structures numbered I to IV?


I

(A)
(B)
(C)
(0)

Sieve pore _ .
Pasmodesma
Plasmodesma
Seve plate

II

. sieve tube
sieve plate
sieve~late
. sieve pore

ill

plasmodesma.
sieve pore' .
._sieve pore
sieve tube

IV
companion cell
.sievetube
companion cell ~
plasmodesma

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022070101SPEC2007

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. 19.

Which of the following statements proVides


why sueroserather
the BEST explanation
than glucose is tran~orted by the phloem?

of

(A)
(B)
(C)

(0)

The Mass Flow Theory of the transport of .'


. organic solutes in.the phloem po~tliai
(A)

(B)

(C)

(D)

21.

(A)
. ' (B)

m~crophage ..
..redbloodceU
, '(C), 'neutrophil"
(D) ,.. lymphocyte

-, .
sucrose diffuses frommesophyllcells.
j
'.
into the phloem
along a"
T~e
gr~ph'
beiow, shows ,the 6xygen.
23 .
. concentration gradient
,
.
difsociatiop curve for 1:lUmanhaemoglobin.
. sucrose moves by osmosis into the
phloem when water ascends the,
xylemintOtheleaf'
.
.Sucrose is actively pumped by
.IIl:':
.
,. ~rl!ldllOQ .. ' 'ttl
mesophyll cellS directly into the
phloem against a concentration .
nf1IIln"CIp"tn '5a
dhllll~1lt
ill,
giadient
.
'
sucrose is actively pUr!lped by
.. ~
III .
companion cells mediating between ..
41
....,
.,.
113
. mesophyll cells ~d phloem against
a concentratiOn gradient
'mfl"'tnn~d~II"

I'J '
i: .,'

.'

In which of the following phases of the.


cardiac cycle is a pulSe generated?
(A)
(B)
(C)
(D)

below?
/

,SuCrose passes through plant cell


surface membranes more easily.
Sucrose is a disaccharide and is .
more easily converted to starch. ,.
SuCrose is a non-reducing sugar and
so it is less reactive.
." '
Sucrose synthesis does not require ...

ATP.

20.

. Which of the following correctiy i~tifies the .


mammalian blood cell shoWnin the diagram ,.

,'22 .

, Atrial systole .
Atrial diastole
Ventricular systole
Ventricular diastole

, Which of the following ranges of partiai


pressureS of oxygen would befoUJ?d in
pulmonary arteries?
(A) , BetWeen 0 and3.kPa
Between 3 and 6 kPa .
(B)
,
BetweeIi 6 and 9 'kPa
(C)

(D) . Between 9 aild 12kPa

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02207010/SPEC2007

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-724.

.. Which'ofthefollowingisNOTafunctionof
. the liver?
(A)
(B)
(C)
(0)

Production of plasma proteins


Metabolismoffat
Control of blood sugar
StorageofVitaminsB.CandD

Item 25 refers to a micrograph of part of the cortex of the kidney.

!.

z
25.

"

Which of the following correctly identifies X. Y and Z? .

x
(A) .
(B)
(C)
(D)

Glomerulus
DiStalconvoluted tubule
GlODienllUS
RenaJ.capsule .

0220701O/SPEC2007.

Y.

'.

distal convulutedtubule
renal capsule
renal cap~ule
Gomenllus

renal capsule
glomerulus .
distal convoluted tubule
distal convoluted tubule

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......

..

'

-.t':' -~.

I 'f

1:,(
I

...

.r'.; ".
I
I

~w/ .
!:....,> ~

~. -";'.,0,

and . '

.26.

Which of the follo~g indicates the sire


mechanism for the reabsorptiQIl of giucose
into the blood capillaries from Ii human
. kidney nephron?

~~:

28. ' . In Ii cho1iD.eigicsYnapse; calciumions(Ca2+)


are involved in the transrirlsSion of nerve
impulses by~',
. . (A)

Mechanism
(A)

Collecting duct Actiye transport

(B)

Distalconvoluted tubule

generating an action potential of


. +4OInv inthe postsynaptic knob'
(B) " depolarit1ng the presynaptic Imob by
". entering the neurone
.'
(C) . restorfug the resting potential of the
neurone by leaviJig the cell '
(D); ,triggering.
the
release
of
... nfmrotransmitterfrom the synaptic
vesicles '.

.'

'.

...

Passive diffusion

(C)

. ,(D)

. Glorllerulus' '.. Selectiveteabs


tion .' '.,'
ProxiiIial.
convoluted
tubule.'

29. . .' Which of the following combinatiom correctly


. , : '. identifieScharacteristics of both giucagon and

. Activetr~ort

iDsiilint "

.,

Insulin

Glucagon

.(A)

.Item 27tefers to the diagram below. .

(B)

..

J"...,.,,""
'it
.1N at
"I

(C)
(D)

8'

I. ..-

......
(;

30.
"

.j
41!:

27.

The diagram shows the' changes in


'metpbtanepermeability when a stimuluS'is
applied to a neurone. In which region of the
action potential-A, B, C or D,do soduimions ..
begin to move in? .

'j'

Which thIee of the following combinatiolls


. correctly. describeS .the featUres which 'are
typicalof endocrine CoIIimunication?
.
, I. " : TransttJi.ssionlSslow /
.' n.Responseis
slow __
ill;"
Response is reversible
Iv. '. Jiesponse is widespread
(A)
(B)

(C)
(D)

. I, Uand monly
L ill and IV. only
. iI, illaud IV only
I, II and IV only.

"'-

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02207010/SPEC2007

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-931.

As women pass 50 years of age tltey ~uire


less iron and more calcium in their diets. '
Which statement
provides
the BEST
, explanationforthis?

34.

The graph shows the development


infeCtion with huInanimmwi~eficiency
(HIV) over a period of 10 years.
DCq

32.

0-

-RlV,

Blood cells are more readily broken


down and must be replaced.
Women at that age need. to replace
(B)
calcium lost during child bearing
years.
,(C) '. Menstruation is gradually reducing,
and bone loss is increasing
(0) . . Less .active' women would NOr
require as 'manY ,bloqd cells to be .
'manufactured ...
(A)

of an
virus

...
T"tfb

During. starvation, the FIRsT reserve used


by the body to maintain energy levels is .
. The patient is MOST likely to fiist .show
. symptoms of AIDS at point

. (A), . sf<)redglycogen .
. (B) .' protem in muscle .
.
(C) . "vitaniinS stored in liver .
(0)
stored fat

(A)
(B)

A.
B

(C) C
(0)

I)

33. , . Astudent iJivestigates the immediate effects .


of exerciseo~
the body and records
folloWing reswtS
'

the'

PulseJbeat$
..1
DllD.

. Systolicblood
pressure/min He

At rest

60

110

5 mins

75

130

iOmins

80

165

Time

3S.

Which of the following is NOT a mode of


. transmission of the human fmmune deficiency
virus (HIV)?
.' (A)
(B)
(C)
(0)

Intimate sexual cOntact


Containination with infected blood
Mother's breast1Dllk to her baby
Mosquito saliva and transfer ofblood

I:

Which of the following is the percentage


change in blood pressure after 10 minutes of
exercise?

(A)

45%

(B).'
(C)

50%
. 55%

(D)

60%

36.

,Which of the following is the human body's


first lille of defence against invading
pathogens?
.
(A)
(B)

(C)
(D)

The production of antibodies


The production of antigens
The ingestion of pathOgens by B.lymphocytes
.The ingestion
of pathogens
by
phagocytes

OOONTq~NmITR~aB'
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'

1 ' ~ '::

i'

.-~~'---

~ :. p ~....
.'

-10 -

.1

37.

;/

Cells that divide and give rise to lytnphoc}'tes . 39 ..


are called stem cells. In which of the
following structures of the human body do ..
these stem cells Carry out their division? .
. (A)
(B)
(C) .
(D)

.,

(A)
'(B)
(C)
(D)

Bone marrow
Spleen
ThymUs.
Lymphnodes'
40.

Item"38 refers to the folloWingdiagram which' ..


illustrates an antibody molecule., . - .

1. -

Which of the following options besttieSCribes


the type of immunity that resuItsfi:'O'm.taking.'
an oral vaccine for ~olio?

'. AIllOliocloilalantibodyis
(A)"
(B)
'(C)
, (D).

0--

The two labels which represent the ~tigen


. binding site and the region which gives
flexibility m bmding to antigens are
. (A)
(B)
(C)
(D)

. ..

. a SJIUillquantity of several antibodies --.


Imide by Olle particular type of Biymphocyte.
.'
_, made by fusmg lymphocyte w!~ba
. .somatic cell .
. produced by T cells after .expOsure .
. to 'one particuiar antigen. .

Long term' eJq>osUre of the liver to. high .


concentril1ions of alcohol eveni:ually t:eSults
. fuliverfailun;. This is due.to the development
of the disease called. i (A)

38.

Active natural immimity


Passive natural immunity
'.' Active artificial immunity
Passive artificial immunity

(B)'
(C)
(D)

CirrhoSis ..
. -Multiple sClerosis
Atherosclerosis . .
Arteriosclerosis

1and 3
2.and3
3 and 4
1 and 4

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02207010/SPEC2007

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42.

11 -

The table below shows the effects of three components of tobacco


. smoke (X., Y. Z) in humans.

y-

Lung cancer

Constriction of
~eS

Reduces the oxygen carrying capacity ofblood

Mucus secretion '.


high

Releaseof
adrenaline

Combines with haemoglobin

Which of the following correctly identifies X. Y and Z?

.'

.'

(A)

Tar.

.Carbon monoxide

Nicotine

(B)

Tar

Nicotine

Carbon monoxide

(C)

Nicotine

Carb~n monoXide

Tar

(0)

43.

NicotiIie

Tar

.Carbon.monoxide

Item 45 refers to the diagram below showing


a map of. a plasmid shoWing the positions' of
recognition sequences of two restriction
enzymes.

. What is the name of the enzyme used to


produce. sections of DNA from messenger
RNA for use illgenetic engineering?

(A)
DNApolymeri1se
. (B) " Reverse traD.scriptase
(C),
Restriction endonuclease .
(0)
RNA polYmerase
....

44.'

Which of the following DNA IIlolecUlescan


be sectioned by usiD.ga restriction enzyme
with a recognition site of MIT?
(A)

GCTTGCATAAGC
CGAACGTATTCG

45.

In an experiment to use this plasmid as a .


vector for thebuman insUlin gene. for which
of the following reasons would the genetic
engineer choose the Bani location to rot this
plasmid?

(B)

CATGGCATGGCA
GTACCGTACCGA

(C)

AGTTCAGGTACC
TCAAGTCCATGG

(A)

TACCG,TTAAGCT
ATGGCAATTCGA

(B)

(0)

(C)
(D)

....IFYOUFJN;lS1lBEFORETIMEIS
02207010/SPECt007

The
insulin
gene' is not
complementary to the Eco RI
restriction site
Bam HI makes a staggered cut
To allow identification
of the
recombinant plasmid
The gene for tetracycline resistance
is needed for the expression of the
insulin gene.
'/

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