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Question Bank

What is Drug Metabolism?


What are the Phase I and Phase II Reactions? Explain with suitable examples.
What is Glucuronic acid conjugation?
Explain the various conjugation Reactions with suitable examples.
What are the factors affecting Drug Metabolism?
What are Antibiotics?
What are the various classes of Penicillin.
What are the Penicillinase resistant Penicillins
What are the AminoPenicillins
What are the Antipseudomonal Penicillin

What are the various classes of Cephalosporins. Write down its SAR.

Write down the synthesis of Cefadroxil.

What are the various classes of Tetracyclines


Write down the SAR and MOA for this.
What are the Antimicobacterials
What are the Polypeptides antibiotics
What is Chloramphenicol?
What Are the Sulphonamides.Give its SAR and MOA.
Classify the sulphonamides.
What Are the Quinolones
What Are the Aminoglycosides

What is malaria?Classify various antimalarials drugs.


Give the SAR of Quinolones.
What are Biguanides?
What are Antiamoebic drugs?

What are Antiprotozoal drugs

What are Antelmintics drugs?


Write down the synthesis of Niclosamide.
What are Antifungal drugs?
Give the structure, uses, properties and the synthesis of Clotrimazole
What are Peptide Proteins?
Give the life cycle of Virus.
What are Reverse Transcriptase inhibitors?
What are the HIV protease Inhibitors
What is AIDS? How will you treat this?

What is Cancer? Classify the anticancer drugs with suitable examples


What are the nitrosoureas?
Write down the synthesis of Antimetabolites.
Give the structure, uses of Bleomycin.
What are Steroidal Hormonal agents?
What are Enzyme nhibitors?
What are Chemotherapeutic agents?
What are Mannich bases?

What is Diabetes? Classify this.


What are the various Insulin preparation
Classify the varoius Oral hypoglycaemic agents. Give their Structures and synthesis of any two
drugs.
Write down the structure of Sulfonyl urea? Give its Synthesis.
Give the structure and synthesis of Biguanides

What is Thyroid?
What are the drugs used for the treatment of Hyperthyroidism?

What are the Diagnostic Agents?


Give the synthesis of Iopanoic Acid.

What are Pharmaceuticals Aids? Explain with suitable examples


Write a note on Colouring, Flavouring and Sweetening Agents

QUESTION BANK AND


ASSIGNMENTS

ASSIGNMENT 1

2 marks type:
1. Write the structure and use of Tolnaftate.
2. Write the structure of Clotrimazole and mention its use.
3. Write the structure of Griseofulvin and mention its use.
4.
5.
6.
7.
8.
9.

Write any two structures of Quinolones, and mention their uses.


Write the structure of Nitrofurantion and mention its uses.
Write the structure and use of Ethambutol and Isoniazid.
Write structure of any two antitubercular antibiotics.
Write the synthesis and uses of Nalidixic acid.
Classify anti tubercular agents, giving examples along with their

structures
10. Write any two structures of antiviral agents, write their structures
and mention their uses.
11. What is Cotrimoxazole? Mention its therapeutic use.
12.
Write the structure and use of Trimethoprim.
13.

Write the structure and use of Metronidazole and Diloxanide furoate.

14.

Write the structure and use of Emetine hydrochloride.

15.

Write structures of Chloriquine and Pyrimethamine.

16.

Give examples for Biguanides as antimalarials and mention their

uses
17. Give an example for betalactamase inhibitors and mention its use.
18. Write structure and use of Ampicillin
19.

Mention uses of tetracyclines.

20.

Write uses of Polypeptidal antibtiotics.

21.

Write plant products as anticancer drugs.

22.

Write the structure of Methotrexate and mention its use

5 marks type:
1. What are anti fungal agents? Classify them giving examples with
structures.
2. Write any two examples for Imidazoles as antifungal agents.
3.
4.
5.
6.
7.

Mention their uses.


Write a note on antifungal antibiotics.
Write the synthesis and mention its use.
Write the SAR of Quinolones and mention their uses.
Write a note on antitubercular antibiotics.
Write the synthesis and uses of Ethambutol and Isoniazid.

8. Classify anti tubercular agents, giving examples along with their


structures.
9. Write a note on antitubercular antibiotics.
10.
Write the synthesis and uses of Ethambutol and Isoniazid.
11.
What are antiviral drugs? Classify them giving examples,
along with their structures.
12.
Write the SAR of Sulfonamides.
13.
Write the synthesis of any two sulfonamides and mention
their uses.
14.
How do you modify the structure of Sulfonamides to develop
drugs that do not cause crystlurea.
15.

Classify antiprotozoal drugs, along with their structures.

16.

Write the synthesis of Metronidazole, and mention its use.

17.
18.

Write the SAR of quinoline group of antimalarials.


What causes malaria? Write the malarial cycle. Classify

antimalarial drugs
19.

What are beta lactam antibiotics? Classify them giving

examples.
20.

Write a note on semisynthetic penicillins.

21.

Write a note on broad spectrum penicillins.

22.

Write the chemistry and uses of Aminoglycosides.

23.

Write the SAR of tetracyclines, and mention their uses.

24.

What are Macrolidal antibtiotics? Give their uses.

25.

Write the stereochemistry of Chloramphenicol and mention its

uses.
26.

Write the synthesis and uses of Chloramphenicol.

27.

Write the mechanism of action of alkylating agents as

anticancer drugs.
28.
Classify antimetabolites as anticancer drugs giving their uses.
29.
Give the synthesis of Cyclophosphamide.mention its use.

10 marks type:
1. Classify Anthelmintics, write the synthesis of Mebendazole.
2. Write the synthesis of any two anthelmentics.
3. What are Sulfonamides? Classify them giving examples along with
their structures.
4. Classify sulfonamides, write the SAR of Sulfonamides.
5. Classify antimarial drugs, write the synthesis of any two antimalarial
drugs.
6. Write the synthesis of any two Antimalarials and mention their uses.
7. What are antibiotics? Classify them, giving examples.
8. What are Penicillins? Classify Semi-synthetic penicillins along with
their structures.
9. Discus chemistry and chemical degradation of Pencicillins.
10.
What are tetracyclines? Discuss their chemistry, SAR, and
uses.
11.
What are antineoplastics? Classify them giving examples.
12.
Write note on alkylating agents as anticancer drugs. Mention
its mechanism of action and uses.

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