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Emsley HCA, Hapkins SJ (2008) Acute ischaemic stroke and infection: recent
and emerging concepts.Lancet Neurol 7: 341-53
2. Enggel O, Meisel A (2010) Models Of infection before and after stroke:
Investigating new targets. Infect Disord Drug Targets 10: 98-104
3. Emsley HCA, Smith CJ, Gavin CM, Georgiou RF, Vail A, Barberan EM,
Hallenbeck JM, del Zappo GJ, Rothwell NJ, Tyrrel PJ, Hopkins SJ (2003) An Early
and sustained peripheral inflammatory response in acute iskemic stroke:
relationship with infection and artherosclerosis. J Neuroimmunol 139:93-101
4. Smith CJ, Emsley HCA, Gavin CM, Georgiou RF, Vail A, Barberan EM, del Zoppo
GJ, Hallenbeck JM, Rothwell NJ, Hopkins SJ, Tyrell PJ (2004) peak plasma
interleukin-6 and other peripheral marker of inflammation in the frist week of
ischemic stroke correlate with brain infarct volume, stroke severity and longterm outcome. BMC Neurol 4:2
5. Offner H, Subraimanian S, Parker SM, Afentoulis ME, Vandenbark AA, Hurn PD
(2006) Blood Flow Metab 26: 654-65
6. Offner H, Subramanian S, Parker SM, Wang C Afentoulis ME, Lewis A,
Vandenbark AA, T cells and circulating macrophages. J Immunol 176: 6523-31
7. Gendron A, Teitelbaum J, Cossette C, Nuara S, Dumont M, Geadah D, du
Souch P, Kouassi E (2002) Temporal effects of left versus right middle
cerebral artery occlusion on spleen lymphocyte subsets and mitogenic
response in Wistar rats. Brain Res 955: 85-97
8. Prass K, Meisel C, Hoflich C, Braun J, Halle E, Wolf T, Ruscher K, Victorov IV,
Priller J, Dirnagl U, Volk HD, Meisel A, (2003) Stroke induced
immunodeficiency promotes spontaneous bacterial, infections and is
mediated by sympathetic activation reserval by poststroke T helper cell type
1- like immunostimulation. J Exp Med 198:725 36
9. Stevens SL, Bao J, Hollis J, Lessov NS, Clark WM, Stenzel-Poore MP (2002) The
use of flow cytometry to evaluate temporal changes in inflammatory cells
Folowing focal cereberal ischemia in mice. Brain Res 923: 110 9
10. Prass K, Ruscher K, Karsch M, Isaev N, Megow D, Priller J, Scharff A, Dirnagl U,
Meisel A (2002) Desferioxamine indeces delayed tolerance against cereberal
ischemia in vivo and in vitro. J Cereb blood Flow Metab 22:520 5
11.Maloy KJ, Powrie F (2001) Regulatory T cells in control of immune pathology.
Nat Immunol 2:816 22
12.Rancalor MG, Levings MK (2000) The role of deffernt subsets of T regulatory
cells in controlling autoimmunity. Curr Opin Immunol 4:330 6
13.Shevach EM (2000) Regulatory T cells autoimmunology Annu Rev Immunol
18:423 49
14.Fontenot JD, Gavin MA, Rudensky AY (2003) Foxp3 Programs the development
by the transcription of CD4+CD25+ regulatory T cells Nat Immunol 4:330 6
15.Hori S, Namura T, Sakaguchi N (2005)
Control of regulatory T cells
development by the factor Foxp3. Science 299: 1057 61
16.Khattri R, Cox T, Yasayko S, Ramsdell F (2003) An essential for scurfin in
CD4+CD25+ regulatory T cells. Nat Immunol 4: 337 42
17.Sakaguchi S, Sakaguchi N (2005) Regulatory T cells in immunologic selftolerance and autoimmune disease. Int Rev Immunol 24: 211 26

18.Shimizu J, Yamazaki S, Sakaguchi S (1999) Induction of tumor immunity by


removing CD25+CD4+ T cells: a common basis between tumor immunity anf
autoimmunity. J Immunol 163: 5211 8
19.Belkaid Y, Piccirillo CA, Mendez S, Shevach EM, Sachs DL (2002) CD4+CD25+
regulatory
T cell control Leishamania major persistence and immunity.
Nature 420: 502 7
20.Palonczyk MJ, Hopke C, Vandenbark AA, offner H (2006) Estrogen- mediated
Immunomadulation involves reduced activation of effector T cells,
potentiaton of Treg cells, ande enhancedlation of the PD-1 costymulatory
pathway. J Neurosci Res 84:370 8
21.Planas AM, Gomez Choco M, Urra X, Gorina R Caballero M, Chamorro A
(2012) Brainderived antigens in lymphoid tissue of patiens with acute stroke.
J Immunol 188: 2156 63
22.Ren X, Akhiyoshi K, Grafe MR, Vandenbark AA, HUrn PD Herson PS, Offner H
(2012) Meylin Specific cells infiltrate MCAO lesions and exacerbate stroke
severity. Metab brain Dis 27: 7 15
23.Jones RE, Bourdette DN, Whitham RH, Offner H Vandenbark AA, (1993)
Induction of experimental autoimmune encephalomyelitis in severe combined
immunodeficient mice reconstituted with allogenetic or xenogenetic
hematopoitec cells. J Immunol150: 4620 9
24.Hurn PD, Subramanian S, Parker SM, Afentoulis ME, Kaler LJ, Vandenbark AA,
Offner H (2007) T- and B-cell defecient mice with experimental stroke have
reduced lesion size and inflammation. J cereb Blodd Flow Metab 27: 1798
805
25.Yilmaz G, Arumugam TV, Stroke KY, Granger DN, (2006) Role of T
lymphocytes and interferon in ischemic stroke. Criculaon 113: 2105 12
26.Jander S, Kraemer M, Schoeter M, Witte OW, Stoll G (1995) Lympocytic
infiltration and expression of intercullar adhesion molecule-1 in
photochemically induced ischemia of the rat cortex J Cereb Blood Flow Metab
15: 42-51
27.Schoeter M, Jander S, Witte OW, Stoll G (1994) Laocal immune responses in
rat cereberal cortex after middle cereberal artery occlusion. J Neuroimmunol
55: 195 203
28.Becjer KJ, McCarron RM, Reuzler C, Laban O, Sternberg E, Flanders KC,
Hellenbeck, JM (1997), Immunologic tolerance to myelin basic protein
decreases stroke size after transient focal cereberal ischemia. Proc Natl Acad
Sci USA 94: 10873 8
29.Nadareisivili ZG, Li H, Wright V, Maric D, Warach S, Hallenbeck JM, Dambrosia
J, Barker JL, Baird AE (2004) Elevated pro-inflammatory CD4+CD28Lymphocytes and stroke recurrence and death. Neurology 63: 1446 51
30.Ren X, Akiyoshi K, Dziennis, Dziennis Vandenbark AA, Herson PS, Hurn PD,
Offner H (2011) Regulatory B cells limit CNS Inflammation and neurologic
deficits in murine experimental stroke. J Neurosci 31: 8556 63
31.Gee JM, Jalil A, Shea C, Becker KJ (2007) Lymphocytes: potensial mediators of
postischemic injury and neuroprotrction. Steoke 38 (Suppl 2):783- 8

32.Wang Q, Tang SN, Yenari MA, (2007) The Inflammatory response in stroke. J
Neuroimmunol 184:53 68
33.Liesz A, Suri-Payer E, Veltkamp C, Doeer H, Sommer C, Rivest S, Giese T,
Veltkamp R (2009) Regulatory
T cells are key cerebroprotective
immunomodullators in acute experimental stroke. Nat Med 15: 192- 9
34.Planas AM, Gorina R, Chamorro A (2006) Signalling pathway mediating
inflammatory responses in brai ischemia. Biochem soc Trans 34:1267 70
35.Grilli M, Barbieri I, Basudev H, Brusa R, Casati C, LOzza G, Ongini E (2000)
Interlukin-10 modullates neuronal threshold of vulnerability to ischemic
demage. Eur J Neurosci 12: 2265 72
36.Vila N, Castolo, J, Davlos A, Esteve A, planas AM, Chammorro A (2003) Levels
of anti inflammatory cystokines and neurological worsening in acute ischemic
stroke. Stroke 34: 671 5
37.Chamorro A, Amaro S, Vargas M, Obach V, Cervera A, Torres F, Planas AM
(2006) Interleukin 10, monocytes and incrraced risk of early infection in
ischemic stroke . J Neurol NeuroSurg, Psychiarty 77: 1279 81
38.Ishida Y, Agata Y, Shibara K, Honjo T, (1992) induced expression of PD-1 ,
Anovrl member of the immunoglobin gane superfamily, upon programmed
cell death. EMBO J 11: 3887- 95
39.Keir ME, Francisco LM, Sahe PT, Sharpe AH, (2007) PD-1 and ints ligands in T
cell Immunity.Curr Opin Immunol 19: 309 14
40.Nishimura H, Minato N, Nakano T, Honjo T, (1998) Immonologica Studies on
PD-1 deficient mice: implication of PD-1 as a negative regulator for B cell
resposes. INt Immunol 10: 1563 72
41.Farcisco LM, Sage PT, Sharpe Ah (2010) The PD-1 pathway in tolerance and
autoimmunologi. Immunol Rev 236: 219 -42
42.Okazaki T, Hanjo, T (2006) The PD-1 PD-L pathway in immunological
tolerance. Trends Immunol 27: 195 201

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