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2009

ASHP National Clinical Skills Competition

LOCAL CASE

2009 ASHP Clinical Skills Competition

LOCAL COMPETITION CASE

Directions to Clinical Skills Competition Participants


Identify the patients acute and chronic medical and drug therapy problems. Recommend interventions to address the drug therapy
problems using the forms supplied (Pharmacists Patient Data Base, Drug Therapy Assessment Worksheet [DTAW], and
Pharmacists Care Plan).
IMPORTANT NOTE: Only the Pharmacists Care Plan will be used for evaluation purposes. The Drug Therapy Assessment
Worksheet is simply a tool to assist you in the decision-making process.

ASHP CLINICAL SKILLS COMPETITION 2009

PHARMACISTS PATIENT DATA BASE FORM


Demographic and Administrative Information
Name: SC
Address: 2087 Bentley Ave
Charlotte, NC
Date of Birth: 12/17/1973
Height: 163cm (54)
Weight: 54 kg
Gender: Female
History of Present Illness
You are on rounds with the Internal Medicine team on 4/5/09 outside
the patients room. Dr Graham, the attending physician, has diagnosed
this patient with Pneumocystis jirovecii pneumonia and esophageal
candidiasis. Dr Graham believes SCs pneumonia is improving. SC
will not be started on antiretroviral medications at this time. Nurse
Jones steps out of the patients room and informs the team that the
patient has become increasingly anxious overnight. Dr Graham would
like recommendations from the pharmacist for SC. The information
below contains the patient's history, physical exam, laboratory data,
and other information up to this point.

Patient ID: 2989031


Room & Bed: Room 1064/General Medicine
Physician: Graham
Pharmacy: n/a
Race: African American
Religion: None specified
Vitals & Other Tests
Vitals & Other Tests
4/4/09
4/5/09
BP mmHg
170/95
BP mmHg
165/92
Pulse bpm
130
Pulse bpm
120
Temp
Tmax 102.2F Temp
Tmax 99 F
RR breaths/min 26
RR breaths/min 26
O2 Sat
84% RA
O2 Sat
92% RA
ABG:
pH
7.45
PaCO2 mmHg 35
PaO2 mmHg
65
HCO3 mmol/L 24

SC presented to the emergency department on 4/4/2009 @ 10PM with


a cc of cough and chills and panic-like agitation. She was also
experiencing moderate hand tremor, diaphoresis, nausea and itching
with a sensation of bugs crawling on her skin. She has known HIV
disease but is currently not on prophylaxis or antiretroviral therapy.
Two weeks prior to admission she began to note the onset of a dry,
nonproductive cough, intermittent chills, anorexia, and then
progressive exertional dyspnea. She also complains of severe mouth
and throat pain, as such she refuses to eat or drink. She was admitted
her to the general medicine service, from the emergency department,
for further inpatient management.

This form is to be used ONLY in the ASHP Clinical Skills Competition. Any other use of this form requires permission from ASHP.
2

ASHP CLINICAL SKILLS COMPETITION


PHARMACISTS PATIENT DATA BASE FORM (Cont.)
Past Medical History
HIV diagnosed in 2006
AIDS
Hepatitis C
Alcohol withdrawal related seizures (4/2006 & 12/2008)
Polysubstance abuse
Gravida 4 Para 0

Chemistry and CBC


4/4/09
Na mmol/L
136
K mmol/L
3.5
Cl mmol/L
103
CO2 mmol/L
24
BUN mg/dL
4
SCr mg/dL
0.8
Gluc mg/dL 143
Ca mg/dL
8.4
Mg mg/dL
2.0
Phos mg/dL 0.9
WBC K/L
3.4
Hgb gm/dL 10.0
HCT %
28.6
Plts K/L
260
Neut %
87
Lymph %
2
Mono %
3
Bands %
8
Eos %
0
Baso %
0
Total Protein g/dL 7.0
Albumin g/dL 3.1
Alk Phos units/L 205
AST units/L 158
ALT units/L 113
Tot bili mg/dL 0.5
hCG
negative
LDH International Units/L
460
Blood EtOH mg/dL 200

4/5/09
Na mmol/L
138
K mmol/L
3.6
Cl mmol/L
104
CO2 mmol/L
27
BUN mg/dL
5
SCr mg/dL
0.9
Gluc mg/dL 109
Ca mg/dL
-Mg mg/dL
-Phos mg/dL
-WBC K/L
3.0
Hgb gm/dL 10.4
HCT %
29.7
Plts K/L
240
Albumin g/dL 2.7
Alk Phos units/L 206
AST units/L 128
ALT units/L 124
Tot bili mg/dL 0.4
Urine Drug Screen
Amphetamines Negative
Barbiturates Negative
Benzodiazepines Positive
Cocaine Negative
Marijuana Positive
Opiates Negative
Blood EtOH mg/dL 0

Family History
Unknown

This form is to be used ONLY in the ASHP Clinical Skills Competition. Any other use of this form requires permission from ASHP.
3

ASHP CLINICAL SKILLS COMPETITION


PHARMACISTS PATIENT DATA BASE FORM (Cont.)
Social History (from outpatient chart)
Tobacco: denies
ETOH: drinks approximately twelve 12 oz cans of beer per day, she
reports that she has not had any beer in the 12 hours before presenting
to the emergency department due to severe mouth and throat pain and
difficulty swallowing.
Illicit Drugs: Past history of occasional marijuana, last used about 2
weeks ago; crack cocaine, last used about 1
month ago
Caffeine: denies
Occupation: unemployed
Status: divorced/has boyfriend who is HIV negative (last HIV test 1
month ago).
Children: None (states she can not afford her birth control)
Physical Activity: denies
Diet: Nothing notable

Procedures

Cultures
4/5/09

Blood Culture X2 No Growth


AFB Smear X 3 No Growth
AFB Culture No Growth
Fungus Culture No Growth
Stool Culture No Growth
Sputum Gram Smear: <10 epithelial cell seen/LPF;
<10 PMN/LPF, 1+ Gram Positive Cocci; 2+ Gram
Positive Rods, 1+ Gram Negative Rods, 1+ Yeast
Pneumocystis DFA Stain 1+ Pneumocystis
jirovecii
Immunology 4/5/09
Hep A
Reactive
Hep B Surface Ag
Nonreactive
Hep B Core Total Ab
Nonreactive
Hep C Virus Ab, Riba 3.0 Positive
HIV 1 RNA
3,531,673 copies/ml
CD4
2 cells/mm3
PPD 4/5/09 @ 0800
Pending
X-ray
Chest (taken in emergency department on 4/4/09)
Reading: diffuse interstitial hilar infiltrates with ground glass
appearance most prominent in the right mid lung field
Interpretation: consistent with Pneumocystis jirovecii
pneumonia
Chest (4/5/09) unchanged.

Physical Exam 4/5/09


General: Thin female in acute distress with shortness of breath and obvious agitation
Skin: Moist; no lesions, tumors or moles; no palmar erythema
HEENT: Normocephalic; atraumatic; deferred remainder of exam due to agitation; sclerae are anicteric
Chest: Tachypneic, labored breathing; decreased breath sounds in the right middle lung field
CV: Regular rhythm; tachycardic; no murmurs, gallops, or rubs
Abd: Soft, tender to palpation, moderately distended; (+) bowel sounds; liver span enlarged at 2 cm below right costal margin; no
splenomegaly; no spider angiomata
Ext: Moves all extremities; (+) tremor in both hands

This form is to be used ONLY in the ASHP Clinical Skills Competition. Any other use of this form requires permission from ASHP.
4

ASHP CLINICAL SKILLS COMPETITION


PHARMACISTS PATIENT DATA BASE FORM (Cont.)
Allergies/Intolerances
No known drug allergies

Current Scheduled Drug Therapy


Drug Name/Dose/Strength/Route

Prescription Coverage
Insurance: None
Copay: not applicable
Cost per month: not applicable
Home Pharmacy: none known

1.

Ceftriaxone 1gm IV

Q24 hours

Duration StartStop
Dates
4/4/09 present

2.

Azithromycin 500mg PO

Q24 hours

4/4/09 present

3.

Sulfamexthoxazole/Trimethoprim
800-160mg PO (1 tab)
Nystatin suspension 500,000 units PO
Enoxaparin 40mg SQ
Omeprazole 20mg PO
Multivitamin 1 tab PO
Drospirenone/Ethinyl estradiol 1 tab

Q12 hours

4/4/09 present

Q8 hours
Q24 hours
Daily
Daily
Daily

4/4/09 -- present
4/4/09 -- present
4/4/09 -- present
4/4/09 -- present
4/4/09 -- present

Empiric for community acquired


pneumonia
Empiric for community acquired
pneumonia
Treatment of Pneumocystis jirovecii
pneumonia
Treatment for esophageal candidiasis
Venous Thromboembolism prophylaxis
-Vitamin replenishment
Birth control

Once
Once
Once

Once
Once in ED
Once @ 4AM 4/5/2009

Testing for Tuberculosis


Agitation
Agitation

Q4 hours prn
pain/fever
Q4 hours prn
Q4 hours prn moderate
to severe pain
Q4 hours prn
Q6 hours prn nausea
Q6 hours prn nausea
Q6 hours prn anxiety

4/4/09 -- present

Mild pain/fever

4/4/09 -- present
4/4/09 -- present

Dyspnea
Moderate to severe pain

4/4/09 -- present
4/4/09 -- present
4/4/09 -- present
4/4/09 -- present

Dyspnea
Nausea
Nausea
Agitation

4.
5.
6.
7.
8.
PO
9. Tuberculin PPD 0.1ml ID
10. Lorazepam 1mg PO
11. Lorazepam 1mg IV
Current PRN Drug Therapy
1. Acetaminophen 500mg PO/PR 1-2 tabs
2. Albuterol Inhaler 1-2 puffs
3. Hydrocodone 5mg/Acetaminophen
500mg 1-2 tabs
4. Ipratropium Inhaler 2 puffs
5. Ondansetron 4mg IV
6. Ondansetron 4mg PO
7. Lorazepam 1mg PO

Prescribed Schedule

Indication

Medication History
Patient is non-adherent with medicine at home. She has a prescription for Yaz (drospirinone/ethinyl estradiol) at home but can not afford
this medicine, and thus does not take it.

This form is to be used ONLY in the ASHP Clinical Skills Competition. Any other use of this form requires permission from ASHP.
5

Drug Therapy Assessment Worksheet (DTAW)


The Drug Therapy Assessment Worksheet (DTAW) will serve as a guide to identify any drug-related problems that your patient may have. You may make notes on the DTAW. However, the Drug Therapy Assessment Worksheet will not be scored. As you proceed through all the questions on the DTAW, you will
accumulate a list of drug therapy problems. All of these problems should be assessed on your Pharmacists
Care Plan. Drug-related problems may be listed as separate items on your Pharmacists Care Plan or addressed in your recommendations for therapy of the acute or chronic disease states that the medicines are
being used to treat. Teams will be evaluated on identifying and making appropriate recommendations for
drug-related problems in the following areas below:
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.

Correlation between drug therapy and medical problems


Appropriate drug selection
Drug regimen
Therapeutic duplication
Drug allergy or intolerance
Adverse drug events
Interactions: drugdrug, drugdisease, drugnutrient, and druglaboratory test
Social or recreational drug use
Failure to receive therapy
Financial impact
Patient knowledge of drug therapy

15
6

Not evaluated
for Competition

ASHP CLINICAL SKILLS COMPETITION


DRUG THERAPY ASSESSMENT WORKSHEET (DTAW)
Type of Problem

Assessment

Presence of Drug-Related Problem

Correlation between Drug


Are there drugs without a medical
1.
Therapy and Medical
indication?
Problems
2.

Are any medications unidentified (are any

unlabeled or are anyprior to admission/
3.

clinic visitunknown)?

Comments/Notes

A problem exists.
More information is needed for a determination.
No problem exists or an intervention is not
needed.

Are there untreated medical conditions?


Do they require drug therapy?

Appropriate Drug
What is the comparative efficacy of the
1.
Selection
chosen medication(s)?

2.

What is the relative safety of the chosen

medication(s)?
3.


Has the therapy been tailored to this

individual patient?

A problem exists.

Drug Regimen
Are the prescribed dose and dosing
1.

frequency appropriatewithin the usual

therapeutic range and/or modified for
2.

patient factors?

3.

Is pm use appropriate for those

medications either prescribed or taken

that way?

A problem exists.

Is the route/dosage form/mode of


administration appropriate, considering
efficacy, safety, convenience, patient
limitations, and cost?

Are doses scheduled to maximize


therapeutic effect and compliance and to
minimize adverse effects, drug interactions,
and regimen complexity?

Is the length or course of therapy


appropriate?

Therapeutic Duplication

Are there any therapeutic duplications?

More information is needed for a determination.


No problem exists or an intervention is not
needed.

More information is needed for a determination.


No problem exists or an intervention is not
needed.

1. A problem exists.
2. More information is needed for a determination.


3. No problem exists or an intervention is not
needed.
Drug Allergy or
Intolerance




Is the patient allergic to or intolerant of


any medicines (or chemically related
medications) currently being taken?

1. A problem exists.
2. More information is needed for a determination.

Is the patient using any method to alert


3. No problem exists or an intervention is not
health care providers of the allergy/ needed.
intolerance (or serious medical problem)?

2009, American Society of Health-System Pharmacists, Inc. All rights reserved.

This form is to be used ONLY in the ASHP Clinical Skills Competition.


Any other use of this form requires permission from ASHP.

(continued)

16
7

Not evaluated
for Competition

ASHP CLINICAL SKILLS COMPETITION


DRUG THERAPY ASSESSMENT WORKSHEET (DTAW)
Type of Problem

Assessment

Presence of Drug-Related Problem

Adverse Drug Events


Are there symptoms or medical problems
1.

that may be drug induced? What is the

likelihood that the problem is drug
2.

related?

3.

A problem exists.

Interactions: Drug-Drug,
Are there drug-drug interactions? Are they
1.
Drug-Disease, Drug-
clinically significant?
Nutrient, and Drug-
2.
Laboratory Test
Are any medications contraindicated

(relatively or absolutely) given patient
3.

characteristics and current/past disease

states?

A problem exists.

Are there drug-nutrient interactions? Are they


clinically significant?

Are there drug-laboratory test interactions?


Are they clinically significant?

Social or Recreational Drug


Is the patients current use of social drugs 1.
Use
problematic?

2.

Could the sudden decrease or

discontinuation of social drugs be related
3.

to patient symptoms (e.g., withdrawal)?
Failure to Receive
Therapy



Has the patient failed to receive a


medication due to system error or
noncompliance:

Financial Impact

Is the chosen medication(s) cost effective?

Comments/Notes

More information is needed for a determination.


No problem exists or an intervention is not
needed.

More information is needed for a determination.


No problem exists or an intervention is not
needed.

A problem exists.
More information is needed for a determination.
No problem exists or an intervention is not
needed.

1. A problem exists.
2. More information is needed for a determination.

Are there factors hindering the


3. No problem exists or an intervention is not
achievement of therapeutic efficacy? needed.
1. A problem exists.


Does the cost of drug therapy represent a
2. More information is needed for a determination.

financial hardship for the patient?

3. No problem exists or an intervention is not
needed.
Patient Knowledge of
Drug Therapy





Does the patient understand the purpose


of his or her medication(s), how to take it,
and the potential side effects of therapy?

1. A problem exists.
2. More information is needed for a determination.

Would the patient benefit from education


3. No problem exists or an intervention is not
tools (e.g., written patient education needed.
sheets, wallet cards, and reminder
packaging)?

2009, American Society of Health-System Pharmacists, Inc. All rights reserved.

This form is to be used ONLY in the ASHP Clinical Skills Competition.


Any other use of this form requires permission from ASHP.

17
8

19A

Priority

Therapeutic Goals

2007,American
American Society
Health-System
Pharmacists
, Inc.
All
rights
2009,
Societyofof
Health-System
Pharmacists
, Inc.
Allreserved.
rights reserved.

Health Care Problem

Recommendations for Therapy

*Please note, there should be only a 1, 2, or 3 listed in the priority column, and the number 1 should only be used once.

A. List all health care problems that need to be addressed in this patient using the table below.
B. Prioritize the problems by indicating the appropriate number in the Priority column below:
1 = Most urgent problem (Note: There can only be one most urgent problem)
2 = Other problems that must be addressed immediately or during this clinical encounter; OR
3 = Problems that can be addressed later (e.g. a week or more later)

Problem Identification and Prioritization with Pharmacists Care Plan

ASHP Clinical Skills Competition - Pharmacists Care Plan

Monitoring Parameters and


Endpoints

Team # _______

Evaluated for
competition

19B

10

Priority

Therapeutic Goals

2007, American
American SSociety
ociety ofof
HeHealth-System
alth-System PharPharmacists
macists, Inc
.A
ll rigAll
hts rrights
eservedreserved.
.
2009,
, Inc.

Health Care Problem

Recommendations for Therapy

Problem Identification and Prioritization with Pharmacists Care Plan

ASHP Clinical Skills Competition - Pharmacists Care Plan

Monitoring Parameters and


Endpoints

Team # _______

E v a l u a te d f o r
c o m p e ti ti o n

19B

11

Priority

Therapeutic Goals

2007, American
American SSociety
ociety ofof
HeHealth-System
alth-System PharPharmacists
macists, Inc
.A
ll rigAll
hts rrights
eservedreserved.
.
2009,
, Inc.

Health Care Problem

Recommendations for Therapy

Problem Identification and Prioritization with Pharmacists Care Plan

ASHP Clinical Skills Competition - Pharmacists Care Plan

Monitoring Parameters and


Endpoints

Team # _______

E v a l u a te d f o r
c o m p e ti ti o n

19B

12

Priority

Therapeutic Goals

2007, American
American SSociety
ociety ofof
HeHealth-System
alth-System PharPharmacists
macists, Inc
.A
ll rigAll
hts rrights
eservedreserved.
.
2009,
, Inc.

Health Care Problem

Recommendations for Therapy

Problem Identification and Prioritization with Pharmacists Care Plan

ASHP Clinical Skills Competition - Pharmacists Care Plan

Monitoring Parameters and


Endpoints

Team # _______

E v a l u a te d f o r
c o m p e ti ti o n

19B

13

Priority

Therapeutic Goals

2007, American
American SSociety
ociety ofof
HeHealth-System
alth-System PharPharmacists
macists, Inc
.A
ll rigAll
hts rrights
eservedreserved.
.
2009,
, Inc.

Health Care Problem

Recommendations for Therapy

Problem Identification and Prioritization with Pharmacists Care Plan

ASHP Clinical Skills Competition - Pharmacists Care Plan

Monitoring Parameters and


Endpoints

Team # _______

E v a l u a te d f o r
c o m p e ti ti o n

19B

14

Priority

Therapeutic Goals

2007, American
American SSociety
ociety ofof
HeHealth-System
alth-System PharPharmacists
macists, Inc
.A
ll rigAll
hts rrights
eservedreserved.
.
2009,
, Inc.

Health Care Problem

Recommendations for Therapy

Problem Identification and Prioritization with Pharmacists Care Plan

ASHP Clinical Skills Competition - Pharmacists Care Plan

Monitoring Parameters and


Endpoints

Team # _______

E v a l u a te d f o r
c o m p e ti ti o n

19B

15

Priority

Therapeutic Goals

2007, American
American SSociety
ociety ofof
HeHealth-System
alth-System PharPharmacists
macists, Inc
.A
ll rigAll
hts rrights
eservedreserved.
.
2009,
, Inc.

Health Care Problem

Recommendations for Therapy

Problem Identification and Prioritization with Pharmacists Care Plan

ASHP Clinical Skills Competition - Pharmacists Care Plan

Monitoring Parameters and


Endpoints

Team # _______

E v a l u a te d f o r
c o m p e ti ti o n

16

17

2009
ASHP National Clinical Skills Competition

LOCAL CASE ANSWER KEY

Evaluated for
competition

ASHP Clinical Skills Competition - Pharmacists Care Plan


Problem Identification and Prioritization with Pharmacists Care Plan

Team # _______

A. List all health care problems that need to be addressed in this patient using the table below.
B. Prioritize the problems by indicating the appropriate number in the Priority column below:
1 = Most urgent problem (Note: There can only be one most urgent problem)
2 = Other problems that must be addressed immediately or during this clinical encounter; OR
3 = Problems that can be addressed later (e.g. a week or more later)
*Please note, there should be only a 1, 2, or 3 listed in the priority column, and the number 1 should only be used once.

Health Care Problem Priority

Acute Alcohol
Withdrawal

Therapeutic Goals

Recommendations for Therapy

Monitoring Parameters and


Endpoints

Prevent acute alcohol


induced delirium tremens
Prevent Wernickes
encephalopathy
Prevent autonomic
instability

Lorazepam 1mg IV q6 hours


Lorazepam 0.5mg IV q2 hours
prn (adjunctive tx to Lorazepam)
Enalaprilat 1.25mg IV q2 hours
prn SBP > 175 (change to
Clonidine 0.1mg PO)
Haloperidol 2mg IV q2 hours
prn severe agitation or
hallucinations (adjunctive tx to
Lorazepam)
Initiate maintenance fluid (1 liter
bag daily) with Dextrose
5%/0.45% NS 1 liter with
Thiamine 100mg-200mg/Folic
Acid 1mg/MVI/Magnesium 2gm
x 3 days
Follow Management of alcohol
withdrawal delirium. An
evidence-based practice
guideline. (2004)

Change to oral therapy when


thrush pain subsides
Vitals (BP/HR) q 4 hours x
72 hours then q shift
Monitor for signs/symptoms
of withdrawal:
tremor,diaphoresis,nausea/
vomiting, fever, agitation,
confusion, sleeplessness,
hallucinations, seizure
(Severity Assessment Scale,
American Journal of Critical
Care, January 1995, Vol.
4(1), 67 OR-- Revised
Clinical Institute Withdrawal
Assessment for Alcohol
(CIWA-Ar) Scale. Br J
Addict 1989;84:1353-7)
Chem 7, Magnesium,
Phosphorus daily x 72 hours

Health Care Problem Priority

Pneumocystis jiroveci
pneumonia

Therapeutic Goals

Recommendations for Therapy

Monitoring Parameters and


Endpoints

Prevent mortality
Appropriate treatment for
opportunistic infection
Decrease hypoxemia

Trimethoprim/Sulfamethoxazole
16ml (256mg TMP/1280mg
SMZ) IV q6 hours
(19mg/kg/day TMP adjusted for
ease of compounding)
Discontinue oral TMP/SMZ
subtherapeutic dosing.
Recognizing the need for IV
medication is key here.
Discontinue Ceftriaxone and
Azithromycin
Prednisone oral solution 40mg
PO BID x 5 days then 20mg PO
BID x 5 days then 20mg daily
for 11 days OR
Methylprednisolone 32 mg IV
BID X 5 days (~64mg daily)
with taper.
Follow Guidelines for
Prevention and Treatment of
Opportunistic Infections in HIVInfected Adults and Adolescents
- April 10, 2009 (p.6)

Change to oral therapy when


thrush pain subsides
Test for G6PD deficiency
Chem 7 (potassium, BUN,
creatinine) daily
CBC daily (w/ ANC)
LFTs daily
Signs/symptoms of allergic
reaction (rash, pruritis)
Maintain adequate hydration
Urine output, q shift
O2 Saturation q shift
GI upset, emotional
instability, glucose w/
Steroid

Health Care Problem Priority

Severe oral and


esophageal thrush

Therapeutic Goals

Recommendations for Therapy

Monitoring Parameters and


Endpoints

Appropriate treatment of
candidiasis

Change to oral therapy when


thrush pain subsides

Pain assessment, including


pain Score (1-10 scale), pain
intensity, pain relief, daily
Quality of life measurement
daily
Change to oral therapy when
thrush pain subsides

Pain Management

Improve pain
relief/minimize pain
Prevent Acetaminophen
toxicity

Electrolyte
Management

Replenish electrolytes
Prevent re-feeding
syndrome

Convert all medicine to IV


therapy when possible
(solutions/suspensions may be
appropriate)
Fluconazole 200mg IV daily x
14-21 days
Discontinue Nystatin
Follow Guidelines for
Prevention and Treatment of
Opportunistic Infections in HIVInfected Adults and Adolescents
- April 10, 2009 (p.46)
Viscous Lidocaine/Maalox 10ml
po q6 hours prn pain
Morphine 2mg IV q6 hours as
needed for mild to moderate
(esophageal) pain.
Morphine 6mg IV q6hours as
needed for severe (esophageal)
pain.
Discontinue
Hydrocodone/Acetaminophen
and Acetaminophen products
Replace phosphate with Sodium
Phosphate 0.24mmol/kg over 6
hours 13 mmol Sodium
Phosphate in 250ml 0.9NS IV
over 6 hours. Repeat x 1 if
needed

Chem 7, Magnesium,
Phosphorus daily x 72 hours

Health Care Problem Priority

Discharge
Planning/Patient
Education

2
OR
3

Opportunistic Infection
Prophylaxis

Therapeutic Goals

Recommendations for Therapy

Ensure patient can obtain


medicine
Establish a pharmacy home
Prevent inpatient
readmission due to nonadherence
Ensure all discharge
medications have an
indication

Appropriate primary and


secondary prophylaxis for
opportunistic infections

Monitoring Parameters and


Endpoints

Contact social worker to enroll


patient in NC Medicaid
Determine pharmacies that are in
close proximity to patients home
and give patient options for a
pharmacy home
Contact chosen community
pharmacist for continuity of
care, medication reconciliation
and comprehensive medication
review.
Patient needs primary
prophylaxis for MAC and
Toxoplasmosis: Azithromycin
1200mg q week. TMP/SMZ
will cover Toxoplasmosis
prophylaxis.
PCP prophylaxis TMP/SMZ 1
DS tab daily (after 21 days of
treatment therapy)
Follow Follow Guidelines for
Prevention and Treatment of
Opportunistic Infections in HIVInfected Adults and Adolescents
- April 10, 2009

Chem 7, CBC q 3 months

Health Care Problem Priority

Contraception/Safe
sexual practices

Therapeutic Goals

Assure pregnancy is
prevented
Assure education of safe
sexual practice

Recommendations for Therapy

Monitoring Parameters and


Endpoints

Discontinue YAZ in the hospital


due to risk of hyperkalemia (with
TMP/SMZ)
Medroxyprogesterone (DepoProvera 150mg IM every 3
months.

OR
Ethinyl Estradiol and
Norethindrone 28-tablet package-1
tablet daily without interruption
OR
Ethinyl Estradiol and
Norelgestromin (Ortho Evra) Apply one patch each week for 3
weeks (21 total days); followed by
one week that is patch-free. Each
patch should be applied on the
same day each week (patch change
day) and only one patch should be
worn at a time. No more than 7
days should pass during the patchfree interval.
OR
Ethinyl Estradiol and Etonogestrel
(Nuvaring) - One ring, inserted
vaginally and left in place for 3
consecutive weeks, then removed
for 1 week. A new ring is inserted 7
days after the last was removed
(even if bleeding is not complete)
and should be inserted at
approximately the same time of day
the ring was removed the previous
week.

Hypercoagulability risk
Side effects: menstrual
irregularities, weight
changes, headache
Counsel on proper use of
contraceptives
Patch or Ring products may
be confusing to use for
patient. Close follow-up
necessary.

Health Care Problem Priority

Polysubstance Abuse
(Alcohol/Cocaine/THC)

Antiretroviral Therapy

Therapeutic Goals

Recommendations for Therapy

Prevent
alcohol/cocaine/THC
withdrawal
Reduce morbidity/mortality

Psych consult
Suggest counseling at each
follow-up visit

Reduce morbidity/mortalty
from HIV related disease

Although she has AIDS stage


HIV, SC will not likely be
started on antiretroviral therapy
until she has issues such as
substance abuse, adherence, and
reason for her acute inpatient
admission resolved.
Patient should be referred for
HIV follow-up at an appropriate
outpatient setting

Monitoring Parameters and


Endpoints

HIV viral load and CD4


count every 3 months
CBC w/ diff every 3 months
Chem 7 every 3 months
Tox Screen every 3 months
or PRN

Note to the local judges:


The Pharmacist Care Plan has been constructed to be as exhaustive as possible. Judges for the Clinical Skills Competition are experts in the field of
clinical pharmacy and will have insights into this case that could not be accounted for in a feasible manner. Thus, as a topic expert, if you identify a
drug related problem that we did not account for, please feel free to judge the students responses based on your best judgment. We can envision
industrious students listing level 3 problems such as: outpatient vaccinations, outpatient cancer screenings, patient literacy assessments, domestic
violence assessments, etc. Please use you discretion in judging these points in the context of the larger case.

Optimal Medication Plan for Inpatient Admission


Current Scheduled Drug Therapy
Drug Name/Dose/Strength/Route
1. Lorazepam 2mg IV
2. Fluconazole 200mg IV
3. Sulfamexthoxazole/Trimethoprim 16ml in
500ml D5W (256mg TMP/1280mg SMZ) IV
4. Prednisone solution 40mg PO
5. Enoxaparin 40mg SQ (a change to Heparin
5000 units SQ q8 hours may be
acceptable).
6. Sodium Phosphate 16 mmol/250 0.9NS IV
7. D5W/0.45% Saline IV with Thiamine
100mg/Folic Acid 1mg/MVI
8. Tuberculin PPD 0.1ml SC
Current PRN Drug Therapy
1. Viscous Lidocaine/Maalox 10ml PO
(swish/swallow)
2. Albuterol Inhaler 1-2 puffs
3. Lorazepam 1mg q2 hours
4. Haloperidol 2mg IV
5. Enaprilat 1.25mg IV
6. Morphine 2mg IV
7. Morphine 6mg IV

Prescribed
Schedule
Q6 hours
Q 24 hours
Q6 hours

Duration StartStop
Dates
HD #2 - present
HD #2 - present
HD #2 present

Indication

BID

HD #2 present (x 5
days)
HD #1 -- present

PJP Pneumonia treatment for


PaO2<70 on admission ABG
VTE prophylaxis

HD #2 Once

Phosphate replenishment/prevent
refeeding syndrome
Thiamine/Dextrose Prevent
Wernickes Encephalitis/Vitamin
replenishment

Q24 hours

Once (over 6
hours)
50ml/hour

HD #2 present (x 3
days total)

Once

HD #1 Once

Q4 hours prn

HD #2 present

Q4 hours prn
Q2 hours prn
Q2 hours prn
Q2 hours prn
Q6 hours prn

HD #1 -- present
HD #2 present
HD #2 -- present
HD #2 present
HD #2 -- present

Q6 hours prn

HD #2 -- present

2009, American Society of Health-System Pharmacists, Inc. All rights reserved

Prevent acute alcohol withdrawal/DTs


Severe oral/esophageal thrush
PJP Pneumonia treatment

Pain associated with oral/esophageal


thrush
Wheezing
Mild/Moderate agitation/breakthrough
Severe agitation/hallucinations
SBP > 175
Mild moderate pain associated with
oral/esophageal thrush
Severe pain associated with
oral/esophageal thrush

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