VISION

A premier university in
historic Cavite recognized
for excellence in the
development of morally
upright and globally
competitive individuals.

MISSION
Cavite State University shall provide
excellent, equitable and relevant
educational opportunities in the arts,
science and technology through quality
instruction and relevant research and
development activities. It shall produce
professional, skilled and morally
upright individuals for global
competitiveness.

Republic of the Philippines

CAVITE STATE UNIVERSITY
Don Severino Delas Alas Campus
Indang, Cavite

Name of Patient (Initial): L.O

Age: 37 years old
Drug Name
Generic
Name:
Cefuroxime
Axetil
Cefuroxime
Sodium
Brand Name:
(Ceftin[P.O])
(Zinacef
[Parenteral])

Mechanism of Action
It binds to one or more
of the penicillin-binding
proteins which inhibits
the final
transpeptidation step of
peptioglycan synthesis
in bacterial cell wall

Indications
*Pharyngitis, tonsillitis,
infections of the urinary
and lower respiratory
tracts, and skin and skinstructure infections
*Serious lower respiratory
tract infections,UTIs,skin
and skin-structure
infections, bone and joint
infections,septicemia,meni
ngitits and gonorrhea
*uncomplicated UTIs
*otitis media
*perioperative prevention
*Early Lyme disease
(erythema migrans)

Action

Date of Admission: August 27, 2014

Diagnosis:
Contraindication and
Cautions

Second-generation
cephalosporin that
inhibits cell-wall
synthesis,promoting
smtic instability;usually
bactericidal
ADVERSE ACTION:
CV: phlebitis,
thrombophlebitis
GI:
pseudomembranous
colitis, nausea,
anorexia, vomiting,
diarrhea
HEMATOLOGIC:
Transient neutropenia,
eosinophilia, hemolytic
anemia,
thrombocytopenia
SKIN:
Maculopapular and

*Contraindicated in
patient hypersensitive to
drug
*use cautiously in
patients hypersensitive to
penicillin because of
possibility of crosssensitivity with other
betalactam antibiotics
*Use with caution in
breast feeding women
and in patients with
history of colitis or renal
sufficiency.

Nursing
Responsibilitie

*Before administerin
make sure patient is
allergic to penicillins
cephalosporins.
*Absorption of
cefuroxime axetil is
enhanced by food.

*Cefuroxime axetil tb
may be crushed if
swallowing is a diffic

*Cefurxime axetil tab

may be dissolved in
small amounts of
apple,orange, or gra
juice, even chocolat
milk.
*High fat meals
increased drug

*Secondary bacterial
infection f acute bronchitis
*Uncomplicated
gonorrhea
*Acute bacterial maxillary
sinusitis

erythematous rashes,
urticaria, pain,
induration, sterile
bscesses, temperature
elevation, tissue
sloughing at
intramuscular injection
site
OTHER:
Hypersensitivity
reactions, serum
sickness,anaphylais

bioavailability.

*ALERT. Cefuroime
axetil film-coated tbl
and oral suspension
not bioequivalent.
*ALERT. Do not
confuse with other
cephalosporins that
sound like.

*Take medicine as
prescribed,even afte
feeling better.

*Take oral form with

food
.
*If suspension is bei
used, shake the
container well before
measuring dose.

*Notify prescriber ab
rashes or
superinfections.

*Notify prescriber ab
loose stools or diarr

VISION
A premier university in
historic Cavite recognized
for excellence in the
development of morally
upright and globally
competitive individuals.

Republic of the Philippines

Don Severino Delas Alas Campus
Indang, Cavite

Name of Patient (Initial): L.O

Age: 37 years old
Sex: Female

Drug Features

MISSION
Cavite State University shall provide
excellent, equitable and relevant
educational opportunities in the arts,
science and technology through quality
instruction and relevant research and
development activities. It shall produce
professional, skilled and morally
upright individuals for global
competitiveness.

Mechanism of
Action

Date of Admission:

Indication

Contraindication

Adverse Effects

Nursing
Responsibilities

Generic Name:
Gentamicin Sulfate
Brand Name:
Lormigin
Classification:
Aminoglycoside
Dosage:
15mg
Route:
IV

It binds to 30s
and 50s
ribosomal
subunits of
susceptible
bacteria
disrupting
protein
synthesis, thus
rendering the
bacterial cell
membrane
defective.

Frequency:
OD

VISION
A premier university in
historic Cavite recognized
for excellence in the
development of morally
upright and globally
competitive individuals.

Name of Patient (Initial): L.O

Age: 37 years old
Sex: Female

Serious
infections
when
causative
organisms are
not known
(often in
conjunction
with a
penicillin or
cephalosporin)

History of
hypersensitivity to
aminoglycoside;
pregnancy;
hepatic
impairment,
perforated ear
drum.

Unlabeled use:
With
clindamycin as
alternative
regimen in PID

Republic of the Philippines

Don Severino Delas Alas Campus
Indang, Cavite

GI:
Dizziness or
vertigo; acute
renal failure,
interstitial
nephritis, acute
tubular necrosis;
electrolyte
imbalances;
transient elevation
of serum bilirubin;
nausea, vomiting;
convulsions,
mental
depression,
hallucinations.

Use 2 mg/mL
intrathecal
preparation without
preservatives, for
intrathecal use.

Patients with
edema or ascites
may have lower
peak
concentrations due
to expanded
extracellular fluid
volume.

Ensure adequate
hydration of patient
before and during
therapy.

MISSION
Cavite State University shall provide
excellent, equitable and relevant
educational opportunities in the arts,
science and technology through quality
instruction and relevant research and
development activities. It shall produce
professional, skilled and morally
upright individuals for global
competitiveness.

Date of Admission: August 27, 2014

Date medication started:

Drug

Mechanism of
Action

Generic:
Paracetamol ,
Acetaminophen

- Decreases
fever by a
hypothalamic
effect leading
Brand: Biogesic, to sweating and
Panadol, Tylenol vasodilation
Classification:
Non-narcotic
analgesic,
Antipyretic
Dosage: 5001,000 mg
Route: Oral, IV
Frequency: 4-6
hrs

Form:

Color: Brown

-Inhibits
pyrogen effect
on the
hypothalamicheat-regulating
centers

Indication
Symptomatic
treatment of
mild to
moderate pain
&/or fever.

Contraindicatio
n
Nephrotoxicity.
Renal
Insufficiency
Anemia

Side effects

Nursing
responsibilities

Occasionally, skin rashes &

hypersensitivity reactions.
Renal damage (long-term
use). Hematological
reactions including
thrombocytopenia,
leukopenia &
methemoglobinemia
resulting to cyanosis.
Minimal GI upset.

1. Do not exceed
4gm/24hr. in
adults and
75mg/kg/day
in children.

1. Methemoglobinemia
2. Hemolytic Anemia

-Inhibits CNS
prostaglandin
synthesis with
minimal effects
on peripheral
prostaglandin
synthesis
-Does not cause
ulceration of
the GI tract and
causes no

3. Neutropenia
4. Thrombocytopenia
5. Pancytopenia
6. Leukopenia
7. Urticaria
8. CNS stimulation

2. Do not take
for >5days fo
pain in
children, 10
days for pain
in adults, or
more than 3
days for fever
in adults.
3. ExtendedRelease
tablets are
not to be
chewed.

4. Monitor CBC,
liver and rena
functions.

anticoagulant
action.

9. Hypoglycemic coma
10.

Jaundice

11.

Glissitis

12.

Drowsiness

13.

Liver Damage

5. Assess for
fecal occult
blood and
nephritis.

6. Avoid using
OTC drugs
with
Acetaminophe
n.

7. Take with food

or milk to
minimize GI
upset.
8. Report N&V.
cyanosis,
shortness of
breath and
abdominal
pain as these
are signs of
toxicity.

9. Report
paleness,
weakness and

heart beat
skips

10. Report
abdominal
pain,
jaundice, dark
urine,
itchiness or
clay-colored
stools.

11. Phenmace
in may cause
urine to
become dark
brown or
wine-colored.

12. Report pain

that persists
for more than
3-5 days
13. Avoid
alcohol.
14.

This drug i

not for regula

use with any
form of liver
disease.
Submitted By: Jenivic Puedan
Year and Section: BSN 4-1
Group: Group 3-B

Submitted To: Jocelyn B. Dimayuga RN, MAN