Drug

Indicatio
n

Dosage

Route

Contraindication

Side effects

Nursing
Consideration

Cefuroxime

Pharyngitis,
tonsillitis,
infection of
the urinary
or lower
respiratory
tracts, and
skin or skinstructure
infection,
UTIs,
septicemia

750 mg q 8o
ANST (-)

IV

-contraindicated in
patients hypersensitive
to drug or other
cephalosporins
-use cautiously in
patients hypersensitive
to penicillin because of
posiibility of crosssensitivity wit other
beta-lactam antibiotics

CV: phlebitis,
thrombophlebitis
GI:
pseudomembranou
s colitis, nausea,
anorexia, vomiting,
diarrhea
Hematologic:
transient
neutropenia,
eopsinophilia,
hemolytic anemia,
thrombocytopenia
GI:
pseudomembranou
s colitis, nausea,
anorexia, vomiting,
diarrhea
Skin:
maculopapular and
erythematous
rashes, urticaria,
pain, induration,
sterile abscesses,
temperature
elevation, tissue
sloughing at IM
injection site
Other:
hypersensitive
reactions, serum
sickness,
anaphylaxis

-before giving drug, ask

patient if he is allergic to
penicillins or
cephalosporins
- Absorption of oral drug is
enhanced by food
Tablets maybe crushed, if
absolutely necessary, for
patients who cant swallow
tablets. Tablets maybe
dissolved in small amounts
of apple, orange, or grape
juice or chocolate milk.
However, the drug has a
bitter taste that is difficult
to mask, even with food

Drug

Indicatio
n

Dosage

Route

Contraindication

Side effects

Nursing
Consideration

Ketorolac

-Short term
manageme
nt of
moderately
severe,
acute pain
for singledose
treatment

30 mg q 6o ANST
(-)

IV

-Contraindicated
inpatients
hypersensitive to drug
& those with active
peptic ulcer disease,
recent GI bleeding or
perforation, advance
renal impairment,
cerebrovascular
bleeding, hemorrhagic
diathesis or
incomplete
hemostasis, and those
with risk for renal
impairement from
volume depletion or at
risk of bleeding.

CNS: drowsiness,
sedation,
dizziness,
headache.

-Correct hypovolemia
before giving ketorolac.

-Contraindicated as
prophylactic analgesic
before major surgery
or intraoperatively

CV: edema,
hypertension,
palpitations
arrhythmias.
GI: nausea,
dyspepsia, GI
pain, diarrhea,
peptic ulceration,
vomiting,
constipation,
flatulence,
stomatitis.
Hematologic:
decreased
platelet edhesion,

-Alert: the maximum

combined duration of
parenteral & oral
therapy is 5 days.
-Dont give drug
epidurally or
intrathecally because of
alcohol content.
-Carefully observe
patient with
coagulopathies and
those taking
anticoagulants. Drug
inhibit platelet
aggregation and can
prolong bleeding time.
This effect disappears

when hemostasis is
critical; and in patients
currently receiving
aspirin, an NSAID, or
probenecid.

purpura,
prolonged
bleeding time.
Skin: pruritus,
rash, diaphoresis
Other: pain at
injection site.

within 48 hours of
stopping drug and
doesnt alter platelet
count, INR, PTT, or PT.