BIOL2146 Cell Structure and Function Lecture and Prac Schedule- 2015

Lecture: Wednesdays at 10:30 AM-12:30 PM in lecture theatre 016.01.001

Lab classes: Wednesdays at 1:30-4:00 PM (Groups P1, P2 or P4, P5)
OR 4:30-7:00 PM (Group P3) in 14.13.007/008
Date/Week
Number

Module #/title

Lecture Topics

Staff

Page references
(Alberts 4th
edition)# ECB

Page references
(MBoC)*

Lab
Class/Groups

4-March
Week 1

Module 1
Introduction to
cells

GN

Ch. 1:pp. 1-37

Ch. 1: 1-12, 14-16, 24-30.

No lab class

11-March
Week 2

Module 1

Course introduction.
What are cells? Domains of
life and big concepts in
biology.
Cell theory. Microscopy and
how scientists study cells.

GN

Ch. 1:pp. 1-37

Ch. 9:579-592; 604-613

Introduction to
microscopes
(P1, P2, P3)

Ch. 2:pp. 39-53

Ch. 2: 45-65; 106-117

18-March
Week 3
25-March
Week 4

Module 2
Biomolecules
Module 2
Biomolecules

15-April
Week 6

Module 3
Biological
membranes and
movement across
membranes
Module 4
Eukaryotic cell
organelles
Module 5
Bioenergetics

22-April
Week 7

Module 6
Enzymes

29-April
Week 8

Module 7
Bioenergetics:
how cells convert
energy.
Module 7

1-April
Week 5

6-May
Week 9
13-May
Week 10
20-May
Week 11

Module 8
Photosynthesis
Module 9
DNA,
replication,
transcription &
translation

Biomolecules: Carbohydrates
Biomolecules: lipids, proteins
and nucleic acids (DNA,
RNA).
Cell and organelle membranes
Transport across membranes

TS

Ch. 2:pp. 53-81

Ch. 4:pp. 121-141

Ch. 2: 45-65; 106-117

Ch. 3: 125-137; 142-148

GN

Ch. 11: pp. 359-381

Ch. 12: pp. 383-396

Ch. 10: 617-648 Ch. 11:

651-667
Ch. 13: 787-792

Cellular organelles,
intracellular trafficking and
the endomembrane system.
Introduction to cellular
thermodynamics. Free energy
and spontaneous reactions.
Introduction to enzymes and
enzyme structure. Factors
influencing enzyme function.

GN

Ch. 15: 487-522

Ch. 15: 695-707

Ch. 15: 713-715

GN

Ch. 3: pp. 83-100

Ch.3: pp. 103-117

Ch. 2: 65-87

GN

Ch. 3: 152-181
Ch. 3: 190

Energy coupling, energy

conservation and transfer ATP
and phosphorylation
reactions.
Glycolysis, fermentation and
cellular respiration.
Photosynthesis: light
reactions,
photophosphorylation and
carbon fixation.
Chromosomes and DNA
replication.
From DNA to protein:
transcription and translation

GN

Ch. 4: pp. 141-157,

168-9.
Ch. 3: 100-102,
104-106.
Ch. 3: pp. 90-117

Ch. 3: pp. 83-116

Micropipettes/
Protein Assay
(P4, P5)

Ch. 13: pp. 419-444

Ch. 14: pp. 447-469
Ch. 14: pp. 469-483

Ch. 2: 88-103
Ch. 14: 813-837
Ch. 14: 840-855

Enzyme Assay
(P1, P2, P3)
Enzyme Assay
(P4, P5)

GN
GN

TS

Ch. 5: pp. 171-185

Ch. 6: pp. 197-211
Ch. 7: pp. 223-259

Introduction to
microscopes
(P4, P5)
No lab: in class
module test.
(All groups)
Cell types and
Osmosis
(P1, P2, P3)
Cell types and
Osmosis
(P4, P5)
Micropipettes/
Protein Assay
(P1, P2, P3)

Ch. 4: 195-202
Fermentation
Ch. 4: 209-211
(P1, P2, P3)
Ch. 5: 266-276
Ch. 6: 329-358
Pp: 366-376, 378-384;
395-6
27-May
Module 10
Cell cycle, Mitosis, Meiosis.
GN
Ch. 18 :pp. 603-633 Ch. 17: 1053-1055
Fermentation
Week 12
Cell division
Ch. 19: pp. 645-657 pp. 1060-1062; 1071-1073; (P4, P5)
1075-1098
Ch. 21: 1269-1281
Lecturers: GN: Dr Gregory Nugent (course coordinator), TS: Assoc. Prof. Trevor Stevenson.
Prescribed Textbook: Alberts et al. (2013) Essential Cell Biology. Fourth Edition, 865 pages. Paperback: ISBN 9780815344551.
http://www.garlandscience.com/product/isbn/9780815344551.
Recommended Textbook: Alberts et al. (2008) Molecular Biology of the Cell. Fifth Edition 1,392 pages: 1,526 illustrations Paperback: 978-08153-4106-2 Companion Website: http://www.garlandscience.co.uk/textbooks/0815341059.asp

Assessment:
Online tests (x10)/ in class written test
Pracs
Exam

25%
25%
50%

Practical skills
Microscopy/basic sectioning/staining/centrifugation
Assays: enzyme function, fermentation, protein concentration
Data analysis: tables, standard curve
Biological drawing
Partner/teamwork