Name of Patient

B. V.

Age

20 y.o

Height

52

Diagnosis

G1P1 PU 31 wks. AOG/LMP cephalic, IPTL, severe

preeclampsia with pulmonary congestion
M. M. Olmillo

Sex

Female

Weight

60 kg

Website

milkv.co.vu

A/N

youre welcome J

Author

DRUG DATA
Generic name:
Azithromycin

CLASSIFICATION
Pharmacologic:
macrolide antibiotic

MECHANISM OF
ACTION

Bacteriostatic
orbectericidal in
susceptible bacteria

Trade name/s:
Zithromax, Zmax
Patients dose:
500mg 1tab OD x
5 days

Therapeutic:
Bacteriostatic

Maximum dose:
2g PO

Onset: varies
Peak: 2.5-3.2 hr

Minimum dose:
250mg

Pregnancy Category
Risk: B

Availability:
Tablets 250,
500, 600mg;
injection 2.5g;
powder for oral
suspension
100mg/5ml,
200mg/5ml,
1g/packet; bottles
for oral
suspension 2g
to be
reconstituted with
60ml water
(Zmax)

Duration: 24 hr
Metabolism: 11-48 hr
Distribution: crosses
placenta, enters
breast milk
Excretion: bile, urine
unchanged

INDICATIONS

General:
treatment of
> lower
respiratory
infections such as
communityacquired
pneumonia
> genital ulcer
disease in men
> uncomplicated
skin infections
> nongonococcal
urethritis and
cervicitis;
treatment of PID
> otitis media
> pharyngitis and
tonsillitis

CONTRAINDICATI
ON

Contraindicated with
hypersensitivity to
azithromycin,
erythromycin, or any
macrolide antibiotic
Precaution:
Use cautiously with
gonorrhoea or syphilis,
pseudomembranous
colitis, hepatic or renal
impairment, lactation

Patients actual
indications:
Azithromycin is
given to patient
for treatment of
acute bacterial
exacerbations of
COPD

Interactions:
> drug-drug: decreased
serum levels and
effectiveness with
aluminium and
magnesium-containing
antacids; possible
increased effects of
theophylline; possible
increased anticoagulant
effects of warfarin
> drug-food: food greatly
decreases the
absorption of
azithromycin

Source: 2011
Lippincotts NDG

Source: 2011
Lippincotts NDG

ADVERSE
EFFECTS

CNS: dizziness,
headache, vertigo,
somnolence, fatigue
GI: diarrhea,
abdominal pain,
nausea, dyspepsia,
flatulence, vomiting,
melena,
pseudomembranou
s colitis
Other:
superinections,
angioedema, rash,
photosensitivity,
vaginitis

NURSING
RESPONSIBILITIE
S

Before:
> check the doctors order
> verify patients identity
> assess for hypersensitivity to
azithromycin, erythromycin, or any
macrolide antibiotic
> assess orientation, GI output,
bowel sounds, liver evaluation
> monitor blood studies
During:
> administer the right drug and right
dose at the right time
> administer on an empty stomach 1
hr before or 2-3 hrs after meals.
> let patient take the full course
prescribed
> do not administer with antacids
After:
> monitor patients blood studies
> assess bowel function for
constipation/diarrhea
> let patient report severe or watery
diarrhea, severe nausea or vomiting,
rash or itching, mouth sores, vaginal
sores
> document and record.

Route:
PO

Source: 2011
Lippincotts NDG

Source: 2011
Lippincotts NDG

Source: 2011
Lippincotts NDG

Source: 2011
Lippincotts NDG

Source: 2011 Lippincotts Nursing

Drug Guide