Beruflich Dokumente
Kultur Dokumente
RELMA
OrIn
Search
of
the
Missing
LOINC
Laboratory
LOINC
Meeting
June
2015
Disclaimer
The
views
and
opinions
expressed
do
not
necessarily
state
or
reect
those
of
the
U.S.
Government,
and
they
may
not
be
used
for
adver?sing
or
product
endorsement
purposes.
Acknowledgements
LOINC
Development
Team
LOINC
CommiLee
Supporters
Overview
of
LOINC
Reviewing
new
RELMA
features!
Installing
RELMA
SeNng
personal
preferences
Loading
a
Local
ObservaJon
File
(LMOF)
Searching
for
a
LOINC
Term
Preparing
LMOF
for
Mapping
Review
of
Map
Screen
FuncJons
SeNng
Search
Limits
Mapping
Local
Terms
to
LOINC
Viewing
LOINC
Term
Details
Proposing/SubmiNng
New
LOINC
Terms
ExporJng/PrinJng
Mapped
Terms
Mapping
your
own
LMOF
data
2014 Regenstrief Institute and James Case
Levels
of
Interoperability
Basic
allows
data
to
be
exchanged
between
computer
systems
Comparability
Meaning
of
the
data
is
consistent
when
shared
among
dierent
parJes
Detailed
General
General
Detailed
2014 Regenstrief Institute and James Case
The
Problem
In
a_empJng
to
arrive
at
the
truth,
I
have
applied
everywhere
for
informaJon,
but
in
scarcely
an
instance
have
I
been
able
to
obtain
hospital
records
t
for
any
purpose
of
comparison.
If
they
could
be
obtained,
they
would
enable
us
to
decide
many
other
quesJons
They
would
show
[subscribers]
how
their
money
was
being
spent
[and]
what
amount
of
good
was
really
being
done
with
it
Florence
Nightingale
-
Notes
on
a
Hospital,
1873
Test
comparisons
What
you
see
in
the
order
list
Lab A
Lab B
Why
LOINC?
Within
one
laboratory,
local
jargon
terms
may
be
used
which
are
usually
well
understood
between
colleagues,
but
would
not
be
suciently
widely
known
for
communicaJon
with
the
outside
world.
U.
Forsum
et
al.,
Pure
Appl.
Chem
72:555-745,
2000
Proper3es
and
Units
in
the
Clinical
Laboratory
Sciences
Part
VII.
Proper3es
and
Units
in
Clinical
Microbiology
2014 Regenstrief Institute and James Case
LOINC
101
Emphasis
on
Laboratory
LOINC
5193-8
Hepa??s
B
virus
surface
Ab
ACnc
Component
Property
Measured
Pt
Timing
Ser
System
Qn
Scale
EIA
Method
TesJng
instrument
Specic
details
about
the
specimen
Priority
(e.g.
STAT)
Where
tesJng
was
done
Who
did
the
test
Test
interpretaJon
Pricing
or
cost
Anything
not
part
of
naming
the
test
Things
from
other
elds
in
an
HL7
arJfact
2014 Regenstrief Institute and James Case
Component/Analyte
The
substance
or
enJty
that
is
measured,
evaluated,
or
observed
-
Sodium
-
Glucose
-
Brucella
sp.
organism
-
Inuenza
A
Virus
anJgen
- Cytomegalovirus
Virus
anJbody
- Lipids.Total
5193-8:Hepatitis
B
virus
surface
Ab:ACnc:Pt:Ser:Qn:EIA
2014 Regenstrief Institute and James Case
Component Structure
Analyte Name^Challenge^Adjustments
Formal analyte name
Calcium
Specify subanalytes
May have subclasses
Challenge
Two parts separated
by post
Adjustments
Coronavirus Ag
Calcium.ionized
Adjusted to pH 7.4
2014 Regenstrief Institute and James Case
Property
the
most
dicult
LOINC
axis
Property
the
most
dicult
LOINC
axis
Ra?o
=
mulJple
analytes
from
same
system
MCrto:
BUN/CreaJnine
in
serum
Rela?ve
Ra?o
=
measures
from
dierent
system
RelRto:
Albumin.pericard
d/Albumin.SerPl
2014 Regenstrief Institute and James Case
PR vs PRID
Timing*
The
interval
of
Jme
over
which
the
observaJon
or
measurement
was
made
Pt
-
at
a
point
in
Jme
12H
-
a
twelve
hour
collecJon
24H
-
a
twenty
four
hour
collecJon
System
The system (context) or specimen type upon
which the observation was made.
Ser
Ser/Plas
Bld
Ur
Flu
Tiss
XXX
serum
serum or plasma
whole blood
urine
body fluid
tissue
specified elsewhere
5193-8:Hepatitis
B2014
virus
surface
Ab:ACnc:Pt:Ser:Qn:EIA
Regenstrief Institute and James Case
System
Structure
System^Super System
Super System
818-5:A Ag:ACnc:Pt:RBC^BPU:Ord:
54417-1:ABO+Rh group:Type:Pt:Bld^fetus:Nom:
Scale
Qn
Quantitative
continuous numeric
can have operators (<,>)
Ord
Ordinal
Ranked set (1+, 2+, 3+)
Nom Nominal
unranked collection
Taxonomy (e.g. bacteria)
Nar
Narrative
5193-8:Hepatitis
B2014
virus
surface
Ab:ACnc:Pt:Ser:Qn:EIA
Regenstrief Institute and James Case
Scale
(Special)
OrdQn
Ordinal
or
QuanJtaJve
Method
Only
needed
if
interpretaJon
aected
AggluJnaJon
Enzyme
Immunoassay
Probe
with
target
amplicaJon
5193-8:Hepatitis
B2014
virus
surface
Ab:ACnc:Pt:Ser:Qn:EIA
Regenstrief Institute and James Case
Hierarchies
LOINC
Class
one
per
term
arbitrarily
assigned
What
is
in
LOINC?
Content
Term
structures
Submi_ed
units,
Example
UCUM
units
Synonyms
Answer
lists
(increasing
number)
Text
descripJons
links
to
info
sources
about
individual
tests
Panel
structures
Foreign
language
translaJons
RELMA
Purpose
of
Tutorial
Eliminate
need
to
read
the
Users
Manual
Become
familiar
with
RELMA
features
Provide
some
insight
into
mapping
Jps/piyalls
Help
begin
the
mapping
process
for
your
insJtuJon
Hang
with
some
really
cool
folks
RELMA
Functions
LOINC
les
and
indexes
Manual
and
automated
mapping
funcJons
RELMA
tools
transform
local
words
in
local
le
Proxy support.
"PanelType
"LForms"
"AssociatedObservaJons
2014 Regenstrief Institute and James Case
RELMA
Highlights
Browse-able
hierarchies
of
LOINC
parts
Display
search
results
in
tree
view
Enhanced
details
view
of
terms/parts
References
DescripJons
Sample
units
Installing RELMA
Installation
Steps
Requires
Windows
(or
VM
on
a
Mac)
Make
sure
you
have
enough
free
disk
space!
2Gb is recommended
File
Locations
Database
and
Ancillary
Files
Sample les
Running RELMA
Version 6.9
Copyright Screen
LOINC crowdsourcing
All Spanish!
File
Locations:
(See
prior
slide
for
location)
Startup
Screen
Preference
Importing
Local
Terms
into
RELMA
Ba_ery/Panel
Code
Ba_ery/Panel
DescripJon
or
Name
*Local
Code
*Test
DescripJon
or
Name
Units
Example
Values
Laboratory
SecJon
Local
Code
Local
DescripJon
Units
(highly
recommended)
2014 Regenstrief Institute and James Case
Manual
Enter/Edit
View/Add/Edit
Local
Terms
Edit\Add\Delete
Terms
Export
Terms
User
assigned
tags
Text
alignment
option
Delimiters
supported:
Tab,
comma,
semicolon,
bar
(|)
BUBPLAG
BUBONIC PLAGUE RRT PCR
Add
tags
Click
to
Add
to
Current
Working
File
Import Button
Fields Segregated
Ready
to
Import
Minimum
assignments
Import
tags
You
can
include
tags
in
your
import
le
that
allow
you
to
categorize
your
local
terms
Fields
in
import
funcJon
allow
assignment
of
Tag
with
Tag terms
Imported tags
OBR
ID
OBR
descripJon
OBX
ID
OBX
descripJon
Sample
of
results
with
Real
values
Units
Abnormal
ags
Normal
ranges
2014 Regenstrief Institute and James Case
Skip
import
of
sample
values
Name
the
Local
Term
File
(working
set)
Import_Sample_OBR.txt
Sample_HL7.HL7
Assign
Replacement
LMOF
AOptions
ttribute
Term Substitution
Comprehensive
Search
Only
Tool
Search
Window
Help
File
Enter
Search
Terms
Limit
to
Specigic
Units
Use
different
logic
Restrict Limits
Search Window
Context Menu
Large
number
of
Restricting
to
Common
results
labs
regines
further
Keyword
ComponentWordCount
restricts
word
count
Large
number
of
results
Answerlist details
Welcome
Screen
Select
the
subset
of
terms
to
work
with:
All
Mapped
Unmapped
Set
your
Search Limits
Bu_on
Customizable
grid
View
details
of
LOINC
term
New!
Add
searchable
tags
to
local
term
Sort
by
column
Click
column
Custom
Sort
Mapping
Screen
View
or
edit
local
term
User
assigned
tags
Congigure
Grid
Select
elements
to
display
Reorder
grid
elements
Begin
a
search
(or
hit
enter)
EEK!
Whatll
I
do?!
Click
to
show
words
used
in
search
2014 Regenstrief Institute and James Case
Use
term
checkbox
Number
of
LOINC
terms
containing
keyword
Battery
terms
included
in
search
Number
of
matching
records
found
Number
of
matching
records
found
Match
units
selected
Navigate
through
the
local
terms
Navigate
to
Functions
from
Mapping
Page
Tree View
Tree
View
Results
displayed
hierarchically
Tree
View
Cannot
map
to
terms
representing
LOINC
parts
(or doubleclick)
If
comments
option
is
selected,
prompt
appears
LOINC
Term
Assigned
Panel Children
Output
Options
Include
column
headers
Save
Congiguration
and/or
Export
LOINC code
AnswerListID
Answer String
Answer tab
More
on
Searching
Search
Screen
Example
Deni?on
Inuenza virus A
AND
Morphine
AND
Opiates
OR
Inuenza
OR
Parainuenza
NOT
Gluc?se
(glucose,glucase)
Gluc*se
(glucose,
glucuronidase,
etc.)
Search Qualigiers
Exclude Glucosidase
Descrip?on
( )
Fieldname:
Fieldname:()
{}, []
91 terms
33 terms
19
terms
2014 Regenstrief Institute and James Case
8
terms
2014 Regenstrief Institute and James Case
Limiting Searches
Toggle Buttons
Search
Constraints
Attribute
trees
Expanded
predegined,
general
search
constraints
Specimen
constraints
CSF
Enter
default
Specimen
Exclude laterality
Exclude laterality
Laterality terms
Restrict
to
common
orders
Common
orders
rank
Large
number
of
candidates
Methodless
Terms
Restriction
Only
Methodless
Terms
Appear
2014 Regenstrief Institute and James Case
Differ
in
one
or
more
components
Conditional
Methodless
More
terms
returned
No
method-less
term;
all
shown
Order/Observation Restriction
Order
or
Observation
preference
2014 Regenstrief Institute and James Case
Three
top-level
branches
Tree
Navigation
Buttons
Large
number
of
candidate
terms
2014 Regenstrief Institute and James Case
Search Trees
Only
Non-Challenge
Chemistry
tests
returned
System Hierarchy
Component
Hierarchy
Click
on
details
for
more
information
about
the
selection
Export
according
to
Congiguration
Extremely
fast
Include
and
exclude
criteria
ParJal
string
matching
(using
wildcards)
Vreeman
DJ,
Finnell
JT,
Overhage
JM.
A
Rationale
for
Parsimonious
Laboratory
Term
Mapping
by
Frequency.
AMIA
Annu
Symp
Proc.
2007;:771-775.
2014 Regenstrief Institute and James Case
Common
in
Microbiology
2014 Regenstrief Institute and James Case
Excel Export
Export
Terms
to
Delimited
File
Select Delimiter
Other
RELMA
Features
2014 Regenstrief Institute and James Case
Double-click
panel
test
to
see
components
Clinical Panels
35089-2, 35090-0
HIPAA Attachments
Select
Propose
a
new
LOINC
Required
gields
in
red
Navigate
through
proposed
terms
301-555-1314
NIH/NLM
301-555-1315
James.case@mail.nih.gov
X
X
X
Choose
whether
to
send
or
postpone
Direct
submission
via
web
All
required
components
gilled
in
The
code
is
from
LOINC
The
code
is
from
SNOMED
OBX-5:
Data
A
c
ode
for
L.
monocytogenes
Q and A Session
Exercise
Map
your
own
data