Code No: 43049/43050 R07 Set No - 1

II B.Tech I Semester Regular Examinations,Nov/Dec 2009

CELL BIOLOGY
Bio-Technology
Time: 3 hours Max Marks: 80
Answer any FIVE Questions
All Questions carry equal marks
?????

1. List out the different cytoplasmic organelles with specific functions within the cell.
[16]

2. Describe the process of exocytosis. What is the significance? [16]

3. Describe the different kinds of intercellular signaling strategies Give a suitable ex-
ample for each strategy. [16]

4. Explain with a suitable example how complex patterns of development are created
by cell-cell interactions? [16]

5. How can you differentiate a Prokaryotic cell from a Eukaryotic cell, give reasons
for the evolution? [16]

6. Explain by schematic representation how replication of damaged DNA can lead to

chromosome abnormalities, gene amplification and gene loss? [16]

7. Prove by an experimental strategy the observation that S-phase Cyclin-Cdk com-

plexes initiate DNS replication only one per cell? [16]

8. Write notes on:

(a) Cytoplasmic streaming

(b) Amoeaboid motion. [8+8]

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Code No: 43049/43050 R07 Set No - 2
II B.Tech I Semester Regular Examinations,Nov/Dec 2009
CELL BIOLOGY
Bio-Technology
Time: 3 hours Max Marks: 80
Answer any FIVE Questions
All Questions carry equal marks
?????

1. Explain in detail how Cdk activity can be suppressed by inhibitory phosphoryla-

tion? [16]

2. Explain in detail, the steps involved in the process of endocytosis. [16]

3. (a) Describe the structure of a G-protein linked receptor?

(b) Explain how trimeric G-proteins disassemble to relay signal from G-protein
linked receptors. [6+10]

4. Discuss various basic features of a cell. Explain their functions. [16]

5. Write about the following.

(a) Cyclic photophosphorylation

(b) Non cyclic photophosphorylation. [8+8]

6. Explain the two mechanisms, an how a morphogen gradient is created during the
process of animal development? [16]

7. The plasma membrane is considered to conform to the fluid mosaic model of cell
membrane preposed by Singer and Nicholson- Explain. [16]

8. Name at least five cancer critical genes that regulate cell division, and describe
their mechanism of action? [16]

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2
Code No: 43049/43050 R07 Set No - 3
II B.Tech I Semester Regular Examinations,Nov/Dec 2009
CELL BIOLOGY
Bio-Technology
Time: 3 hours Max Marks: 80
Answer any FIVE Questions
All Questions carry equal marks
?????

1. Given an account of structure and functions of an mitochondria. [16]

2. Describe the parts of a typical cell and give their functions. [16]

3. Write short notes on:

(a) Receptor mediated endocytosis

(b) Permease. [8+8]

4. Explain the chromosomal translocation events that result in chronic myelogenous

leukemia? [16]

5. (a) Name six signaling ligands and their respective receptors that act via receptor
tyrosine kinases?
(b) Comment on the responses generated in these diverse cell types following re-
ceptor tyrosine kinase activation? [10+6]

6. Define Frizzled / Dishelleved polarity signaling pathway. Explain their role in the
process of convergent extension during gastrula stage? [16]

7. Explain how asymmetric cell division leading to segregation of cytoplasmic compo-

nents to only one daughter cell is achieved? [16]

8. Write about the structure, motion and origin of cilia and flagella. [16]

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3
Code No: 43049/43050 R07 Set No - 4
II B.Tech I Semester Regular Examinations,Nov/Dec 2009
CELL BIOLOGY
Bio-Technology
Time: 3 hours Max Marks: 80
Answer any FIVE Questions
All Questions carry equal marks
?????

1. Write about active transport driven by an ion gradient. [16]

2. (a) What are DNA tumor viruses?

(b) Explain how DNA tumor viruses inactivate the replication machinery? [4+12]

3. Explain the mechanism of bacterial chemotaxis mediated by a two-component sig-

naling pathway of Histidine-kinase-associated receptors. [16]

4. Write short notes on:

(a) TCA Cycle

(b) ATP Synthase. [8+8]

5. What are the types of Eukaryotic cells, how are they specialized. [16]

6. (a) Explain a procedure for creating a chimeric mouse with embryonic stem cells?
(b) What is the role of the foster mother in the generation of a chimeric mouse?
[8+8]

7. Write about the molecular organization of plasma membrane. Illustrate with a

diagram. [16]

8. Describe the sequence of events that are activated when mitogens bind to cell-
surface receptors that is necessary for entry of the cell into S-phase? [16]

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