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flexible
and
modelling
of
approach
generic
chains
supply
to
dynamic
Introduction
It is said that the only constantin today's dynamicbusiness
environmentis change.' Regulatorychanges, globalization,
increasingintensity in competition,increasinglydemanding
customers, new information technology, and mergers and
acquisitions have been promptingimprovementsin supply
chains of various industries,includingthose of the process
industries,in orderto stay aheadof the competition.Thereis
even an axiom highlighting its importance: 'a 1-cent
reduction in supply chain costs can have as much as a
5-cent improvement on operating profits'.2 Supply Chain
Management(SCM) has thus drawna lot of attentionin the
academicand businessworld. In practice,efficientconsumer
response in the grocery industry, efficient healthcare
response in the healthcareindustry, and quick response in
the textileindustryare examplesof SCM tailoredto meet the
needs of the particularindustries.
The term SCM has been broadly used in the literature
with various meanings due to the development of the
philosophy from various perspectives: purchasing and
supply; transportationand logistics; marketing;and level
of coordination.Although differentin origin, these theories
have now merged into a holistic and strategicapproachto
operations,materialsand logisticsmanagement.A definition
At
finishedgoodsto the consumers.
productsto distributing
eachlink,businesses
needto makethebestchoicesaboutwhat
theircustomersneedand how they can meetthoserequirementsat the lowestpossiblecost.'
In other words, the purposeof SCM is to deal effectively
with external strategicchanges, such as globalization,and
operational uncertainties,such as demand fluctuations,in
order to take advantageof any new opportunities,and to
drive down the overall supply costs. Since the cost of
changinga businessstrategyand operationalpolicies can be
huge, it would be wise to have a simulationmodel of the
supply chain network concernedso that various strategies
and policies can be evaluated and comparedquantitatively
before being implementedon the real business.
Since the time correlationof upstreamand downstream
operationsis key to the successof SCM, dynamicstudiesare
particularlyimportantin supply chain improvements.With
dynamicstochasticmodels, it is possibleto assess the effects
of various uncertaintieson the overall performancemeasures, discover where the real bottleneck is and avoid
802 Journal
oftheOperational
Research
Vol.55, No.8
Society
WYHung
et a/l--Dynamic
ofsupply
chains 803
modelling
Generic Node
Material
flow
IMM
MC
OMM
Order
flow
where
Material
IMM= Inbound
Management,
MC= Material
Conversion,
Material
OMM= Outbound
Management.
804 Journal
oftheOperational
Research
Vol.55, No.8
Society
other nodes are not shown here for clarity. For the generic
node in Figure 2, the associations among the components
are describedin the Appendix.The upstreamorderflows are
simulated by order objects being created by the replenishment control policy concernedand accessedby an upstream
node or component. The downstream material flows are
simulated by updating the related stock levels after the
orders are processedby an upstreamnode component.
Replenishmentcontrol policies
Variousreplenishment
controlpolices
controlpolicies
Replenishment
(a)
(b)
(c)
(d)
(e)
(f)
Re-orderpoint (ROP)techniques
Material/distribution
requirements
planning(MRP/DRP)
Basestock control(BSC)
Linerequirements
planning(LRP)
Vendormanagedinventory(VMI)
Just-in-time(JIT)
Generic node
Inboundmaterial
management
consumes/
Material
conversion
,
Resource
Recipe
replenishment
Outboundmaterial
management
expected
produces
dueddces
ke ps
computes
OutboundSKU
supplier
replenishment
issues
Replenishment
control
policy
maintains
triggers
Inventory
FROP
MRP/DRP
SKU
Order
Internalordercontainer
ID
External
by
Internal-m
Externalordercontainer
chains 805
ofsupply
WYHung
eta/-Dynamic
modelling
Vol.55, No.8
806 Journal
oftheOperational
Research
Society
-6
9
11
13
-8
-10
S-12o0
.E0
MC
-16
Figure
for
-6
9
11
13
-8
, -10
c u, -12
2 -14o-
-16
-.-
MC
...........
-20
log2 of number of sampling points
Figure
F= H]f=l(s-xi)/(s-0.5),
TYPES
PLOT
for
where s - 360.
A 1C~r
Hookstack:
i12.tJ
UPLIF
I:UU
[SIMU~llIr4:AVLPAGE
1084
a4
?71
Gi
F,1?
SS
19
(1UG5
77
79
S7
69
71
73
7&
29
31
33
3?
47
49
S3
59
23
27
39
41
43
45
51
21
25
37
Turntidayts)
Figure5 Modelvalidationin a pilot study;the faint lines are
actualdata and bold lines aremodelpredicteddata.
ofsupply
chains 807
WYHung
et al-Dynamic
modelling
Case study
Description
To demonstrate the applicability of the new modelling
method, the supply chain network of a fairly vertically
integratedmultinationalpharmaceuticalcompany is simulated. Based on its existing inventory management and
productionpolicies,the aim is to estimatefor two of its final
products to its external customers:customer service level
(CSL); probability of stock out (PSO); average inventory
(INV), and stock levels over a time horizon of 2 years. In
particular,the customerservicelevel (CSL)is takento be the
fill rate, which is the total quantity sold over the total
quantity ordered,for that SKU market for the whole time
horizon (104 weeks)averagedover all the simulations.When
the stock level is lower than the order quantity, only the
stock availableis sold with no backordersallowed.
Figure 6 shows the simulated supply chain network
configurationand the locations of the various inventories.
There are two marketsand four final products:Packs A and
B are to be sold in the Japanmarket;Packs C and D are to
be sold in the USA market. All of these final products are
made from an Active Ingredient(AI). Packs A and B are
producedin a plant in Asia, while the productionof PacksC
and D are carriedout in a plant in America.The production
of Packs A and B is simulatedas two steps:(1) AI is used to
produce Tablet A, Tablet B, Tablet EurExp, and Tablet
GenExp, then (2) TabletsA and B are packagedto give the
final SKUs PacksA and B, respectively.TabletsEurExpand
GenExp are bulk productsto be exportedwithout packing.
AI, the ingredientfor the Tablets, is in turn producedin a
plant in Europe throughfive synthesisstages. Stockpilesof
the intermediatematerials produced from each stage are
kept in the Europeanplant as buffer stocks.
Asia1
Asia2Jan
0
2AII
Europe 4/5
Europe
RM
I week
Iweek
C
IAl
Euroe3
PB
eek PA,
TA,wTB,
T
P, PB
'
ds TGE
demands
TAATTEE,
Euroe 2
0m
O
14
13
Demand
Management
Secondary Manufacturing
Primary Manufacturing
weeks
America
C
USA
1 weel
PCPD
PC,
PD
demands
.
Key:
I = InboundMaterialManagement,C = MaterialConversion,O = OutboundMaterialManagement
RM = raw material,In = Intermediaten, AI = active ingredient,TA = TabletA, TB = TabletB, TEE= TabletEurExp,
TGE= TabletGenExp,PA = PackA, PB = PackB, PC = PackC, PD = Pack D
808 Journal
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Vol.55, No.8
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Table 2
Node
USA
Japan
SKU stock
Pack A
Pack B
Pack C
Pack D
DRP
4
3000
3000
9000
145
15000
DRP
4
2000
2000
8000
145
15000
DRP
4
5000
5000
45 000
145
60 000
DRP
4
20000
20 000
40 000
145
60 000
Table 3
Node
Asia 2
SKU stock
Replenishment policy type
Safety stock level (weeks)
Minimum order quantity (packs)
Order increment (packs)
Maximum order quantity (packs)
Maximum stock level/safety stock level (%)
Initial stock level (tablets)
Table 4
Tablet A
MRP
3
10000
10 000
200 000
135
2 x 106
Node
SKU stock
Replenishment policy type
Safety stock level (kg)
Minimum order quantity (kg)
Order increment (kg)
Order-up-to-level(kg)
Initial stock level (kg)
Asia 1
America
AI
ROP: (s, S)
200
10
10
300
200
AI
ROP: (s, Q)
150
130
0
180
Table 5
Tablet B
MRP
3
10000
10000
200 000
135
2 x 106
Tablet EurExp
MRP
3
10 000
10 000
200 000
135
2 x 106
Tablet GenExp
MRP
3
10 000
10 000
200 000
135
2 x 106
Node
SKU stock
Replenishment policy type
Target stock level (kg)
Order proportional constant
Intial stock level (kg)
Europe 1
Europe 2
Europe 3
Raw material
Intermediate 1
DynTarget
1200
1
1000
Intermediate 2
DynTarget
1200
1
1000
9 x 106
Europe 4/5
Intermediate 3
DynTarget
2000
1
2000
Intermediate 4
DynTarget
2000
1
2000
AI
DynTarget
1600
1
1500
WYHung
et a/-Dynamic
ofsupply
chains 809
modelling
Table 6
Node
Asia 2
12 Tablet A in
one Pack A
Recipe
Production rate (packs/h)
Nominal production time (h/week)
Overtime allowed (h/week)
America
30 Tablet B in
one Pack B
600 mg AI in
one Pack C
600
40
20
0.1
3
Unavailabilitya
Downtime multipleb
900 mg AI in
one Pack D
1200
60
15
0.1
3
Table 7
Details of the conversion processes for the tablets in Asia Secondary Manufacturing
Node
Asia 1
20 mg AI in
one Tablet A
Recipe
30mg AI in
one Tablet B
30mg AI in
one Tablet
EurExp
40 000 tablets/h
10h/week
0 h/week
0
0
Production rate
Nominal production time
Overtime allowed
Unavailabilitya
Downtime multipleb
30 mg AI in
one Tablet
GenExp
Table 8
Details of the conversion processes for the intermediates in Europe Primary Manufacturing
Node
Recipe
Production capacity
(kg/week)
Unavailabilitya
Downtime multipleb
Europe 1
Europe 2
Europe 3
1 kg raw material
gives 1 kg
intermediate 1
150
1 kg intermediate 1
gives 1 kg
intermediate 2
150
1 kg intermediate 2
gives 1 kg
intermediate 3
250
1 kg intermediate3
gives 1 kg
intermediate4
250
0
0
0
0
0
0
0
0
Europe 4/5
1 kg intermediate 4
gives 1 kg Al
500
0
0
Frozen
period
Scheduling
period
Planning
period
t
100
Dn,t =
Dn,
Gjj20
j=1
2
t = currenttime
Time,t
in the MRPcontrolpolicy.
Figure7 Timeperiodclassification
wheret correspondsto the time step. For these two cases, we
also investigate the effects of replacing the forecast
dependent DRP policies with one of the ROP techniques,
(s, Q), whichis forecastindependent.This can be easily done
of the Operational
Research
810 Journal
SocietyVol.55, No.8
Table9
CSL (%)
Basecase
Case (a): consistentlyunderforecast
(DRP)
Case (a): consistentlyunderforecast
(s, Q)
Case (b):consistentlyoverforecast(DRP)
Case (b):consistentlyoverforecast(s, Q)
Case (c): QC considered
Pack C (USA)
Pack A (Japan)
Experiments
100
84
93
100
PSO (%)
INV (packs)
CSL (%)
3.2 x 104
0.0
1.9x 104
1.8
0.9
2.5 x 104
4.3 x 104
0.0
Sameas base case
Sameas base case
0.0
8.1 x 104
Sameas basecase
Sameas base case
Sameas base case
Sameas base case
7.7 x 104
6.4
100
88
120000
------mean quantity
safety stock
100000 -
95c0 upperconfidence
950o lowerconfidence
80000 x
60000 -
<
40000
o.
20000
0
0
20
80
40
60
Time I weeks
100
INV (packs)
PSO (%)
400000
3
350000
mean quantity
35~0000
safety stock
m.300000 -
950 upperconfidence
950. lowerconfidence
Z 250000
o,
-.
200000 -
?x 100000-
a. 50000
0
20
40
60
80
100
Time / weeks
chains811
ofsupply
WY
etal-Dynamic
modelling
Hung
120000
---
-mean quantity
stock
95% upper confidence
- .safety
95% lowerconfidence
120000a100000
- -80000
.2 100000
95% lowerconfidence
80000
, 60000
60000
40000
a.
mean quantity
safety stock
-- 95% upper confidence
- - - -
CO
20000
. 20000+
20
40
100
80
60
Time / weeks
40
20
60
80
100
Time / weeks
120000
mean quantity
---
" 100000 - o.
98
safety stock
-- 95% upper confidence
95% lowerconfidence
80000
>-
S96
o 94
60000-
o 92
,O
40000
90
88
20000
-YI:...
20
40
60
80
100
Time / weeks
120000
1-)-
safety stock
y 100000
o
a.
.-
95% lowerconfidence
-
80000
60000
CA-
1
0.8
%b
0.6
mean quantity
---
20
40
60
40000
a. 20000-
0.4
0.2
--
- -
I-
80
100
Time / weeks
812 Journal
oftheOperational
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Vol.55,No.8
Society
45000
40000
c 35000
< 30000S25000
0 20000
z 15000
100002
3
4
5
Safety stock cover for Pack A / weeks
References
The
1 BowersoxDJ and Closs DJ (1996).LogisticalManagement.:
Integrated Supply Chain Process. McGraw-Hill: New York.
Appendix
distribution
models:a criticalreviewwithemphasison global
andmethods.IntJ ProdEcon55:281-294.
WYHung
ofsupply
chains 813
eta/-Dynamic
modelling
11 Gjerdrum J (2001). Problems in the optimum planning of multi-
19 Owen AB (1998). Latin Supercube Sampling for very highdimensional simulations. ACM Trans Model Comput Simul 8:
71-102.
20 Sobol' IM (1998). On quasi-Monte Carlo integrations.Math
Comput Simul 47: 103-112.
Wight:Essex Junction,USA.
17 Niederreiter H (1992). Random Number Generation and QuasiMonte Carlo Methods. SIAM: Philadelphia, PA, USA.
18 Sobol' IM (1994). Primer for the Monte Carlo Method. CRC