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CyFlow miniPOC

For CD4 absolute and CD4%

Point-of-Care HIV Monitoring for Primary Health Centers and Remote Areas

routine mode

routine mode

CyFlow miniPOC

expert mode with cell distribution display

truly portable/mobile

fully integrated fluidic system

built-in thermal printer

HIV/AIDS Immune Status Monitoring

DIAGNOSTIC PATIENT
CARE WITHIN A MINUTE
CyFlow miniPOC: The true point-of-care solution

Highlights
_ portable/mobile, compact and robust point-of-care instrument
for CD4 and CD4% testing from one sample run, featuring excellent performance, ideally suited for primary health centers,
PMTCT sites and remote areas
_ easy-to perform quick results, precise and accurate, covering
the full biological range (technical range: 0-5000 CD4/l,
0100% CD4%)
_ rechargeable battery dock (optionally available, for
45 hours operation per battery charge)
_ dimensions [mm]:
268 (W) x 186 (D) x 243 (H)
_ weight < 5 kg
_ both, for low and high capacity:
up to 250 CD4 / CD4% tests per day

_ affordable dry/lyophilized mAb reagents,


eliminating any need for cold chain and cold storage
shelf life: 12 months
_ Windows based analysis software, easy-to-operate
by 5.7 colour touchscreen
_ operated by Intel Atom computer processor
_ built-in thermal printer
_ patient blood analysis with CyFlow miniPOC requires 40 70
seconds, only
_ unique on-screen video operation manual (set-up, sample preparation, instrument operation, maintenance)
_ integrated large data storage: > 20.000 data sets
_ USB ports, e.g. for easy patient data transfer

routine mode

routine mode

CyFlow miniPOC

expert mode with cell distribution display

Quick and easy preparation


for CD4 absolute and CD4%

Step 01
Add 20l EDTA whole blood

After adding EDTA blood


10 min incubation
Partec CD4/CD45
dry mAb tube

CyFlow
and Reagent
miniPOC
Kit

+
Reagent Kit for
CyFlow miniPOC
The Partec miniPOC CD4% count kit
contains all required reagents, the
dry mAb tubes and consumables for
20 CD4/CD4% tests per kit.
No other materials are required.

NEW
On-Screen Video Operation Manual
As absolutely unique feature in the field of CD4 instrumentation, the CyFlow miniPOC - profiting from the
large 5,7 TFT color touchscreen - provides a preinstalled video operation manual with chapters for all
procedures including set-up, sample preparation,
instrument operation, quality control and maintenance.

Step 02
Add prefilled buffer 1 from
tube, shake sample tube

Step 03
Add prefilled buffer 2
from syringe,
shake sample tube

Step 04
Refill volume from sample
tube into syringe

Step 05
Attach syringe to
CyFlow miniPOC

The Complete Point-of-Care Solution.


The absolute number of CD4+ T-lymphocytes and the CD4%

ideally suited as a true point-of-care (POC) solution for primary

among lymphocytes are the most widely used parameters for

health centers and PMTCT sites in all settings. The CyFlow

the immune status monitoring of HIV-infected adults and chil-

miniPOC can successfully be used for high throughput analysis

dren and AIDS patients undergoing antiretroviral therapy. CD4

with up to 250 CD4 tests/day as well as for small health centers

and CD4% testing is commonly organized in larger centralized

in rural areas, measuring only few blood samples. Employing

laboratories resulting in a limited availability of this life-saving

state-of-the-art laser modules, optics, fluidics and electronics,

diagnostic procedure for patients living in remote areas and

the total biological range of CD4 absolute counts and CD4% is

not being capable to travel to laboratories in larger cities.The

covered with unmatched precision, accuracy and reproducibility,

CyFlow miniPOC technology together with the revolutionary

until today only known from extremly expensive and large flow

Partec dry CD4/CD4% test eliminating any need for cold chain

cytometers.

and cold storage allows to perform this immune status analysis without high laboratory infrastructure and specially trained
laboratory staff. The stand-alone instrument with a weight of

The CyFlow miniPOC instrument therefore offers the highest

less than 5 kg can easily be moved close to the patients. The

standard of HIV/AIDS immune status monitoring to everybody

CyFlow miniPOC runs on regular power supplies, recharge-

who needs this important diagnosis, also in remote and rural

able battery pack or optionally on solar panels. It is therefore

areas - always at significantly affordable test cost.

1000

y = 0,9941x - 5,013
R = 0,98883

y = 1,0735x + 0,3289
R = 0,98524

25

800
700

CyFlow miniPOC [CD4]

500
400
300
200
100
0
200

300

400

500

600

700

800

900

1000

National Reference Method [CD4]

Preliminary results from national validation


at NMRL Zimbabwe, CD4 absolute counts
CyFlow miniPOC vs Reference Method

CyFlow miniPOC [CD4%]

20
600

100

Instrument and Reagents

CY-S-3033

CyFlow miniPOC
including starter kit

05-8409-d

Partec miniPOC CD4% count kit - dry, 20 tests


including dry CD4/CD45 mAb reagents, consumables,
sheath fluid and dry QC samples (beads)

Order No.

Options

CY-S-3091

Transportation Bag for CyFlow miniPOC

CY-S-3095

Rechargeable Battery Dock for CyFlow miniPOC


Operation independent from regular power supply:
Work 4-5 hours with the CyFlow miniPOC

CY-S-3097

Solar Panel for CyFlow miniPOC

05-8993

Partec ControlBlood dry, 50 tests


lyophilized and stabilized blood samples,
biological controls for QC/EQA

30

900

Order No.

15
10
5
0
0

10

15

20

25

30

National Reference Method [CD4%]

Preliminary results from national validation


at NMRL Zimbabwe, CD4% results
CyFlow miniPOC vs Reference Method

Contact
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Supplies, after sales service, techsupport, application support and training in >100 countries
worlwide:

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www.cyclos-design.de

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Fax +33 1 69 04 90 38
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