Beruflich Dokumente
Kultur Dokumente
Fakultas
Program Studi
: Farmasi
: Farmasi
Kode/Mata Kuliah
Sks/JP/Sifat Mata Kuliah
Prasyarat
Semester
Tahun Akademik
Dosen
B.
Deskripsi Mata Kuliah
Understanding the important interactions of drugs and their targets, i.e., DNA, RNA and proteins. The course discusses the physicochemical properties
of drugs and how this determines the interactions of small molecules (drugs) with biological macromolecules (proteins and nucleic acids) as the
targets. The course covers also the fundamental mechanisms of the regulation of targets, as well as fundamental molecular interactions important for
both detection and diagnostic applications for drugs and metabolites. The following are the selected contextual topics in medicinal chemistry to be
discussed in this course as examples: (i) Cholinergics, anticholinergics, and anticholinesterases; (ii) The adrenergic nervous system; (iii) The opium
analgesic; (iv) Antiulcer agents; (v) Antibacterial agents; (vi) Antiviral agents; and (vii) Anticancer agents.
C.
Bobot
Nilai
(%)
(6)
10
30
Cholinergics,
anticholinergics, and
anticholinesterases | The
adrenergic nervous system.
Bentuk
Pembelajaran
Pertemuan Ke-
Materi Pembelajaran
(1)
1
(2)
Able to define and classify drugs, distinguish
between drugs and medicines, explain basic
concept of drug targets and how drugs bind to
them.
(3)
(4)
Classification of Drugs | Discovery learning,
Drugs and the Medicinal small group
Chemist | The why and the discoussion
wherefore: Drug targets
2-5
Kriteria
(Indikator)
Penilaian
(5)
Accuracy
Referensi
(7)
Pertemuan Ke8-11
Materi Pembelajaran
as
drug
Bobot
Nilai
(%)
20
10
Referensi
Nucleic
targets
Pharmacokinetics
related topics
12
Antibacterial agents
13
Antiviral agents
Anticancer agents
10
14
acids
Kriteria
(Indikator)
Penilaian
Lecture, small group Accuracy
discussion
Bentuk
Pembelajaran
and
E. Penilaian/evaluasi
Pada bagian ini diuraikan alat penilaian/evaluasi untuk mengukur ketercapaian standar pembelajar
No
Bobot (%)
1.
Action
2.
Group Projects: Create and play board games to study drug-protein interactions
Action
15
3.
Written
30
4.
UTS II - 2nd Mid test: Summary on medicinal chemistry aspects of a particular drug in the market
(Individual Project/Take Home Exam)
Written
10
5.
Written
40
Total
F. Referensi
1. Patrick, G.L., 2005, An Introduction to Medicinal Chemistry, 3rd edition, Oxford University Press.
100%
Fakultas
Program Studi
:
:
Farmasi
Farmasi
Kode/Mata Kuliah
Sks/JP/Sifat Mata Kuliah
Prasyarat
Semester
Tahun Akademik
Dosen
B. Rancangan Tugas
Project 1: Individual Project: Create index cards to study amino acids properties
Tujuan Tugas
Uraian Tugas
a Objek Garapan
b
Able to identify and explain the nomenclature of amino acids and their properties
Summary of amino acids nomenclature and their properties. It can be accessed in http://molmod.org/enade/medchem_1st_2013-2014/
(password: farmasiusd)
The index cards should be shown in the 2nd lecture (week 2). The studentss knowledge about amino acids nomenclature and their
properties will also be tested in the 2nd lecture (week 2).
1)
2)
3)
4)
Able to identify and explain the nomenclature of amino acids and their properties by learning from the index cards.
Group of 6-8 students create and play a board game to study drug-protein interactions. The game should be shown and played in front
of lecturer in the 5nd lecture (week 5). The studentss knowledge about drug-protein interactions will also be tested in the 5nd lecture
(week 5).
1)
2)
3)
4)
5)
A particular marketed drug. The list of drugs will be announced in the lecture 3rd (week 3).
Download the example and the template from http://molmod.org/enade/medchem_1st_2013-2014/ (password: farmasiusd)
Write the summary on (an) A4 paper(s) (maximum 2 pages) on the selected drug following the template.
Submit the printed version of the summary to the class chairperson.
The chairperson submit all papers sequenced by the students number to the lecturer (via lecturers locker)
Deadline of the submission to the lectuter is November 10th, 2014 12.30 WIB
1)
2)
3)
Download the example and the template from http://molmod.org/enade/medchem_1st_2013-2014/ (password: farmasiusd)
Write the summary on (an) A4 paper(s) (maximum 2 pages) on the selected drug following the template.
Submit the printed version of the summary to the class chairperson.
Fakultas
Program Studi
:
:
Farmasi
Farmasi
RUBRIK PENILAIAN
=========================================================================================================================
A. Identitas Mata Kuliah
Kode/Mata Kuliah
Sks/JP/Sifat Mata Kuliah
Prasyarat
Semester
Tahun Akademik
Dosen
B. Rubrik Penilaian
Komponen
Penilaian
Sangat Baik
Baik
Batas
Dibawah Standar
Project 1: Individual Project: Create index cards to study amino acids properties (5%)
Correct Index Cards.
Correct Index Cards.
Correct Index Cards.
Incorrect index
Correctly identify some
Incorrectly identify some cards/Could not show the
(70-85)
examples.
examples.
index cards on time.
( 85)
(56-69)
( < 56)
Skor
Komponen
Penilaian
Sangat Baik
Baik
Batas
Dibawah Standar
Skor
Project 2: Group Projects: Create and play board games to study drug-protein interactions (15%)
Acceptable/understandable
Acceptable/understandable
Acceptable/understandable Could not show the board
board game.
board game.
board game..
game on time.
Correctly explain some
Incorrectly identify some
(70-85)
( < 56)
examples.
examples.
( 85)
(56-69)
UTS II - 2nd Mid test: Summary on medicinal chemistry aspects of a particular drug in the market (Individual Project/Take Home Exam) (10%)
Discipline (on time Correct format, complete aspects
Correct format, complete
Acceptable format,
Unacceptable format or
submission) and
covered in the paper.
aspects covered in the paper
complete aspects covered could not submit on time.
Accuracy
( 85)
with minor mistakes.
in the paper with major
( < 56)
mistakes.
(70-85)
(56-69)
Discipline (on time
submission) and
Accuracy
85,00
Nilai Huruf
20,00 - 55,99
< 20,00