Beruflich Dokumente
Kultur Dokumente
Understanding life seems like the Hindu tale in which 6 blind men
touch an elephant and try to explain what it is. Every single one of
them reaches a different conclusion based on where they touch it and
in the end they are all correct, but its never the entire animal. Weve
wished upon stars, done experiments, even created gods to
understand life and hence biology... I believe, however, that the key to
unfolding this big picture is much closer to us than the distant galaxies;
it has been hidden in plain site all along in the form of a minuscule
four-letter alphabet in the cores of our cells, and now we may get to
find out what it actually is.
Every DNA has a unique sequence of four nitrogenous bases-A,G,T,Cthat encodes for the proteins that determine the traits of living
creatures. And sequencing this alphabet, genome sequencing, may
create myriad opportunities for humanity in the future.
Every organism is formed from a single cell that differentiates into
different cells and parts that defines its species but in the end the
complete genome still exists in every differentiated cell; some genes
are simply turned off. The genetic code does change/evolve but its
never destroyed. Similar to this process, it is believed that all of life
originated from a single cell: the Last Universal Common Ancestor
a.k.a LUCA. All endeavors toward finding LUCAs sequence has been
about trying to emulate the right conditions in which it was born, but
we cant resurrect an unknown language. Why shouldnt we use the
language at hand thats sole purpose has been to copy that first
information ever and bring it into the future? By the aid of genome
sequencing, if we were to sequence the genetic code of every domain
just like we sequenced the human genome, we could theoretically form
a common sequence that may lead us to the genome of LUCA, since
even in our more evolved forms we bare pieces of that first cell that
ever divided 3.8 billion years ago. Finding LUCA would mean finding
the very origin of life, which would not just answer scientific questions,
but religious and philosophical ones as well and put ancient arguments
to rest.
A scientist put a quote from a novel in the genetic sequence of a
bacteria which proved that DNA was a reliable source information
storage and not just useful for protein synthesis. I believe that this
reveals two things. First that the noncoding, so called junk DNA can
be a yet to be deciphered information storage unit that can reveal data
about the very formation of the genetic code (hence LUCA), so by
sequencing this junk DNA and perhaps comparing it to that of other
species we can decode this ancient time capsule. This will probably