Patients Initials:

Age:

E MILIO AGUINALDO COLLEGE

School of Nursing and Midwifery

Diagnosis:

1113-1117 San Marcelino St. Ermita Manila

NAME OF DRUG
Generic Name:

CLASSIFICATION
Pharmacologic Class

Mechanism of action with

anti nematode

fluorouracil is unknown. Its

medication for the

effects on the immune

treatment of

Therapeutic

system are complete, but it

Ascarisis(roundworm)

Antineoplastic

appears to restore depressed

and

immune function rather than

Ancylostoma(hookwor

stimulate response to above-

m) infection.

Pregnancy Risk Category

normal levels. It also can

It is also used as an

stimulate antibody formation;

adjunctive drug in

enhance T-cell responses

treatment of

Immunomodulator
Trade / Brand Name:

Patients dosage: 150 mg/day

Route of Administration
Oral

INDICATION
Levamisole is used an

Levamisole

Ergamisol

MECHANISM OF ACTION
Drug is an immunomodulator.

malignancies (eg.
Pharmacokinetics
Onset Rapid
Peak 1 1/2-2 hrs
Duration Unknown

Colon cancer)

CONTRAINDICATIONS

Contraindicated in patients with history

of pre-existing blood disorders; during
pregnancy and lactation; inflammation
of joints, severe kidney problems.
PRECAUTION
Avoid using alcohol when on levamisole
medication, as it causes antabuse, reaction
characterised by severe abdominal pain,
flushing, dizziness and headache.

SIDE EFFECTS

CNS:
Memory loss, loss of consciousness, fatigue,
tingling, seizures and speech disturbances.

NURSING RESPONSIBILITIES
Dont use drug in higher than recommended
dosage or administer more frequently than
indicated.

Miscellaneous- Muscle weakness, difficulty

in breathing, hives, swelling of lips, tongue,
face, fever and chills.

Before drug therapy begins, patient should

be ambulatory, maintain normal oral nutrition,
have well-healed wounds, be fully recovered
from any postsurgical complications, and not
be hospitalized.

ADVERSE EFFECTS

Obtain CBC with differential, platelet counts,

electrolyte levels, and liver function test
results before therapy.

CNS: dizziness, headache, paresthesia,

somnolence, depression, nervousness,
insomnia, anxiety, fatigue, fever.
CV: chest pain, edema.
EENT: blurred vision,
conjunctivitis, stomatitis, dysgeusia, altered
sense of smell.
GI: nausea, diarrhea, vomiting, anorexia,
abdominal pain, constipation, flatulence,
dyspepsia.
Hematologic: agranulocytosis,
leukopenia, thrombocytopenia, anemia.
Musculoskeletal: arthralgia, myalgia.

If stomatitis or diarrhea develops during

initial fluorouracil administration schedule,
stop course before full five doses are given
If an acute neurologic syndrome occurs,
consider stopping drug immediately.