TREATMENT IN THE EMERGENCY DEPARTMENT Authors: Joan Somes, RNC, PhD, CEN, CPEN, FAEN, and Nancy Stephens Donatelli, RN, MS, CEN, NE-BC, St Paul, MN, and New Wilmington, PA Section Editors: Nancy Stephens Donatelli, RN, MS, CEN, NE-BC, and Joan Somes, RNC, PhD, CEN, CPEN, FAEN
Earn Up to 8.0 CE Hours. See page 413.
t is not uncommon for an older adult to present to the
emergency department with a complaint of abdominal pain related to constipation. In fact, 24% to 50% of independent living adults have constipation, and 74% of residents in long-term care facilities require laxatives daily to keep the bowels functioning at an optimal level. 1-3 Even though ED staff question whether constipation is an emergency, constipation in the adult patient is not only painful and distressing, it can also be life-threatening should it progress to fecal impaction. It should be noted that if an older adult presents with a sudden change in mental status, the differential diagnosis should include constipation and impaction, in addition to all the other factors than can cause mental status changes. 1-3 Other symptoms associated with constipation include lack of passing stool on a regular basis (with each person having his or her own denition of regular), passage of liquid stool while still having a sense of fullness in the colon, having to strain to pass stool, or having to use laxatives, enemas, or suppositories to maintain regularity. Patients may also have crampy abdominal pain and blood-tinged stool from straining and tearing of rectal tissue. Straining during a bowel movement has been associated with syncopal episodes as noted by ambulance personnel who have to extricate the man down from the bathroom on a fairly frequent basis. 1-4 There are 4 typical reasons the older adult may present with constipation. The most common is functional
Joan Somes, Member, Greater Twin Cities Chapter, is Staff Nurse/Department
Educator, St Josephs Hospital, St Paul, MN. Nancy Stephens Donatelli, Member, CODE Chapter, is Project Coordinator, Shenango Presbyterian SeniorCare, New Wilmington, PA. For correspondence, write: Joan Somes, RNC, PhD, CEN, CPEN, FAEN, 5718 Upper 135 St Ct, Apple Valley, MN 55124; E-mail: somes@blackhole.com. J Emerg Nurs 2013;39:372-5. 0099-1767/$36.00 Copyright 2013 Emergency Nurses Association. Published by Elsevier Inc. All rights reserved. http://dx.doi.org/10.1016/j.jen.2013.04.002
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constipation. The patient will present with hard stool that is
difcult and painful to pass. The pain and discomfort associated with functional constipation are generally relieved with passage of the stool. A second reason for constipation is pelvic oor constipationwhere evacuation of stool is compromised because of faulty coordination of the pelvic oor muscle, anorectal structural abnormalities, or impaired perianal descent innervation. A third reason for constipation is slow-transit constipation. This type of constipation is related to partial paralysis in the colon leading to decreased peristalsis. Finally, constipation may be the symptom of a variety of bowel issues, including irritable bowel syndrome, Crohns disease, adhesions, ruptured diverticulum, intestinal cancer, hernia, volvulus, or prolapsed rectum. Before one just assumes that the pain or lack of a bowel movement is related to stool, it will be important to ensure that there is not a specic intestinal issue that is the cause and especially a condition that could be made worse, or even life-threatening, by treating the patient with classic constipation therapies. In general, functional constipation is the most common type and should be addressed rst. If a thorough history and physical, including a digital examination, and use of standard therapies are unsuccessful, then the patient should be referred for testing to rule out the other causes mentioned earlier. 3-6 Although it may not specically be the role of the emergency department to perform a workup related to chronic constipation, some critical thinking and diagnostics by the emergency department may lay the groundwork for the primary care provider. In the emergency department, it often seems that the goal is to x the immediate problem, but in reality education focused on preventing this issue could be more effective in the long run. Generic instructions teaching the patient about diet, exercise, bowel techniques, timing of going to the bathroom, breathing, and positioning on the toilet should be given to anyone who is at risk of having, or currently having, constipation. In addition, if a patient is discharged with a prescription that adds a constipating medication to his or her regimen of pills, the prescription should be accompanied by
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instructions about how to prevent constipation. Sometimes, it
is as simple as recommending mild physical activity rst thing in the morning, a warm beverage, some ber, and some more warm uid to initiate bowel contractions. The patient then needs to take the time to go and sit in the bathroom and let nature take its course. Some of this education is appropriate even as one xes the problem, because many ED actions involve stimulating the bowel. 1-5 The process of xing the bowel requires some serious thought. Before proceeding, the nurse should ensure that the following factors are considered, evaluated, and managed. First, the nurse should determine whether the patient needs to undergo disimpaction. Stool that is packed hard in the rectum will not pass. Breaking up the impacted stool is necessary before the patient will be able to expel the blockage. Simply giving medication to stimulate bowel spasm will not push the stool through. 1,2,4 A second consideration is related to concern that digital manipulation may stimulate the vagal nerve and could potentially lead to bradycardia. One should have knowledge of the underlying risks related to cardiac rhythm, in addition to the recognition that attempts to stimulate the bowel may lead to an increased risk of dysrhythmias, necessitating placement of a monitor during disimpaction, or at least have backup easily available should bradycardia occur. The safety of the practice of administering a Fleet (sodium phosphate) enema to older adults is being questioned more and more. Electrolyte imbalances tend to occur as the gut pulls uid into it. Fluid loss, dehydration, decreases in blood pressure, and extreme increases in phosphate levels and decreases in calcium levels have been seen. In addition, renal function has been noted to deteriorate, acid-base imbalances have been seen, and several deaths have followed administration of sodium phosphate enemas. The current recommendation is to use this type of uid cautiously, if at all, in the older adult. 1,4,6-8 Before instilling any uids into the rectum, many practitioners recommend obtaining a radiograph or computed tomography scan of the abdomen to ensure that there is no free air or indications of a bowel perforation or rupture. A thorough abdominal examination searching for any masses or discomfort is essential before one instills uid into a leaky gut, which can lead to peritonitis. 4-6 Finally, one must consider the patients mobility. Can the patient safely make it to a bathroom, or will he or she need a bedside commode? Can the patient even make it to the commode to have the bowel movement? Will he or she be able to safely sit to pass the stool without falling off the commode? A thorough medication review focused on medications that may lead to constipation often may be facilitated by a pharmacist. However, this responsibility does not eliminate the need for a review by the emergency physician and nursing
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staff. Antacids with aluminum hydroxide and calcium
carbonate are two medications that are notoriously known for leading to constipation. Antispasmodics, antidepressants, iron, anticonvulsants, diuretics, caffeine, alcohol, and narcotic medications are commonly linked to slow bowel motility, hard stool, and constipation. Traveling, the use of public restrooms, and smoking cessation have also been linked to constipation. 1 Obtaining a history of recent travel, current diet habits, uid intake history, and recent smoking cessation and asking the question How much time do you actually spend sitting on the toilet? are important bits of information that can help sort out and identify potential causes of constipation and may help develop a teaching and discharge plan for the patient. General physiological functioning may also need to be evaluated. Thyroid function testing may identify the patient with hypothyroidism, which has been connected with constipation. Checking lead levels could identify lead poisoning as an unusual but real cause of constipation. 3,4 EDoriented therapies for constipation can range from disimpaction and cleansing enemas to medication or admission for surgical intervention or medical treatment. Some tricks to consider include the following: An oil retention enema will soften the stool if given a half hour before any attempt is made to break up the hard stool with a doublegloved nger. A good examination to ensure that there are no painful hemorrhoids, anal ssures, or an anal stenosis that has contributed to the issue is needed. Pretreating the rectal area with a local pain-reducing product typically used for hemorrhoids, including Proctofoam-HC (Duchesnay, Inc, Blainville, Quebec, Canada; hydrocortisone acetate 1% and pramoxine hydrochloride 1%), lidocaine jelly, witch hazel, Preparation H, and other similar products, can make passage of hard stool easier as well. The purpose of the enema is to administer enough uid to stretch the rectum so that a reux squeeze is generated. Use of 500 to 2,000 mL of warm saline solution or tap water will stretch the bowel, leading to a reux spasm that should lead to bowel evacuation. It should be noted that the various additives used over the years (sugar, soap, baking soda, and others) are discouraged because of the irritation that they cause to the bowel and risk of electrolyte imbalance and bowel perforation. It is also recommended that the traditional triple H enema (high, hot, and heck of a lot) be avoided and that the water should be lukewarm. The well-lubricated tip of the catheter is placed no more than 4 inches into the rectum. Cramping is generally a good indication that bowel stretching is taking place and the uid administration should be stopped or at least slowed to allow the bowel to stretch in a gradual manner. In addition to stretching the bowel, the uid makes it easier to pass the stool. Distention of the bowel by uids used during enema
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administration will lead to an evacuation reux. One should
remember that there is a risk of bowel perforation with the enema tip or an excessive amount of or too rapid uid instillation. Perforation may have been present before the enema and part of the reason for the constipation. A small tear in the bowel is especially a risk for the older adult, whose gastrointestinal mucosa tends to be thinner and easier to penetrate and tear. Pain during insertion or instillation of the uid or after uid administration should lead to suspicion of a perforation. In addition, one should remember that the actions of the enema administration equipment may be enough to produce vagal stimulation and resultant bradycardia. 1,4,7-9 In addition to enemas, there are other options that will stimulate the bowels to move. Osmotic agentspolyethylene glycol electrolyte solutions, such as GoLYTELY (Braintree Laboratories, Braintree, MA); the powdered preparations without electrolytes (MiraLAX; Merck & Co, Whitehouse Station, NJ); or synthetic disaccharides, lactulose, magnesium citrate, or milk of magnesiawill all pull water into the bowel and encourage stool movement. Most of these are taken orally and take up to a day to work. If there is a fecal impaction, these products will not be sufcient to yield passage of the stool but will only cause pain and more packing of the stool into the rectum. Sometimes, diarrhea that ows around the impaction will develop because of liquefaction of the stool in the colon but not in the rectal area. This can lead to difculties in making the diagnosis. 1,4,6,7 A staff member recently noted that eating a large number of dietary hard candies could lead to an effect similar to polyethylene glycol electrolyte solutions. Stimulant laxativessuch as bisacodyl, senna, and sodium picosulfate (Dulcolax Drops; Boehringer Ingelheim, Ridgeeld, CT)typically are taken orally to stimulate bowel spasm and stool movement. Suppositories containing glycerin or bisacodyl will also stimulate bowel contraction. They also pull liquid into the gut, and the waxy carrier for the medication contained in the suppositories helps to liquefy the stool, providing a secondary benet of the suppository. Suppositories tend to have an effect in 1 or 2 hours versus waiting several hours to days for the oral laxatives to take effect. 1,4,6,7 Recently, a new type of drug has been introduced to the market that, though not specically a laxative, does assist in emptying the bowel of slowly moving stool, especially if the patient is taking a narcotic that is leading to slow bowel function. Methylnaltrexone works on the receptors of the gut. A single subcutaneously injected dose of this medication works similarly to naloxone by displacing the opioid from the receptor sites that affect bowel motility. Alvimopan is an oral medication that works in a similar manner. The good news is that these drugs do not affect the
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TABLE 1
Preventing constipation: Education for ED patients
Medications that can lead to decreased bowel motility and constipation include the following: aluminum antacids, anticholinergics, anticonvulsants, antidepressants, antihistamines, barium, calcium antacids, calcium channel blockers, calcium supplements, diuretics, iron supplements, levodopa, opioids, and psychotropics. Foods that can lead to decreased bowel motility and constipation include the following: caffeine, alcohol, rened sugar and processed foods, and animal fats (dairy, meat, and eggs). Actions that can lead to decreased motility and constipation include the following: Increased intake of uids, especially warm uids, and increased intake of fruits and vegetables. Increase in exercise. Increase in time sitting on the toilet when the urge strikes. There is a need for more bulktaking a daily dose of a dietary ber or bulk-forming laxative such as psyllium or methylcellulose with extra uid will assist in preventing constipation. In one study, prunes were actually found to be just as effective as psyllium. 10 The recommended dose of ber each day is 20-35 g/d. Bran, 2-6 tablespoons per day with a glass of water, may also prevent constipation. An over-the-counter stimulant laxative can be taken, especially if patients have just been given a prescription for a constipation-causing medication. It is recommended that patients not rely on laxatives, and if they do, they should taper off of them and attempt to keep the bowels regular with uid, bulk, and exercise.
pain-relieving properties of the opioid. Initially used in areas
that served patients with chronic painful illnesses, such as cancer, these drugs have recently been introduced to ED personnel to consider for patients presenting with constipation related to pain medication. Methylnaltrexone, in particular, has been shown to have predictable and quick results (a bowel movement within 1 hour!). One testimonial regarding this stated, Once it workslook out! Its as if the entire gut relaxes and the entire stool comes out in one big rush! The caution was to be ready with a close commode or bathroom. This drug can be readministered every other day for chronic constipation but recently has been marketed to the emergency department as a one-shot x. 1,6 Some older adults are so frail and so constipated that the safest approach is to admit them to the hospital for a gentle evacuation of the bowel. Constipation is generally not an admittable diagnosis, but if the patient is having signicant pain associated with the constipation or has other underlying medical conditions, especially bowel issues such as those noted earlier, he or she may meet criteria for
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admission. The risk of peritonitis is great with constipation,
particularly as the gut attempts to move stool and meets resistance. Coordinating with the physician and case manager is in the patients best interest. 1 The inspiration for this article came from an older adult who frequently presents to the emergency department with complaints of abdominal pain and constipation. Fortunately, this visit did not require disimpaction. It was determined after the emergency physician did a complete examination and testing that it was safe to administer a tap-water enema, which produced satisfactory results. During this time, it was also identied that the patient could use additional education on how to keep his bowels moving regularly. The nurse and the pharmacist spoke with the patient about his medications and found that, indeed, he was taking several medications that could lead to constipation. It was also determined that the patient did not have the best diet and did little exercise. Education related to improving bowel motility took place, and the patient went home with a smile on his face and a parting note to the nurse that he was going to try the things suggested. Educational information for the ED patient regarding preventing constipation is presented in the Table 1. REFERENCES 1. Toner F, Claros E. Preventing, assessing, and managing constipation in older adults. Nursing. 2012;42(12):32-9. 2. McKay SL, Fravel M, Scanlon C. Management of constipation. J Gerontol Nurs. 2012;38(7):9-15.
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3. Mayo Clinic. Chronic constipation in older patients. Mayo Clinic Briefs.
http://www.mayoclinic.org/medicalprofs/constipation-older-adultspudd0412.html. Accessed February 20, 2013. 4. Schaefer DC, Cheskin LJ. Constipation in the elderly. Am Fam Physician. 1998;15(4):907-14. http : //www.aafp.org/afp/1998/0915/p907.html. Accessed February 20, 2013. 5. Basson M, Katz M, Anand BS. Constipation in adults. Emedicinehealth. http://emedicine.medscape.com/article/184704-overview. Accessed February 20, 2013. 6. Gu M, Gonzalez CE, Todd KH. Emergent management of constipation in cancer patients. Emerg Med. 2011;43(11):6-12. 7. Pray WS. Enema products: uses and cautions. US Pharmacist. http:// legacy.uspharmacist.com/oldformat.asp?url=newlook/les/Cons/feat. cfm&pub_id=8%. Accessed March 10, 2013. 8. Ori Y, Rozen-Zvi B, Chagnac A. Fatalities and severe metabolic disorders associated with use of sodium phosphate enemas. Arch Intern Med. 2012;172(3):263-5. 9. Lippincott, William, and Wilkins on line procedure manual. http:// lippincottsolutions.com/solutions/lnps. Revised July 7, 2012. Accessed March 11, 2013. 10. Wald A. Management of chronic constipation in adults. UpToDate. http://www.uptodate.com/contents/management-of-chronic-constipationin-adults. Published 2013. Accessed February 20, 2013.
Submissions to this column are encouraged and may be sent to
Joan Somes, RNC, PhD, CEN, CPEN, FAEN somes@black-hole.com or Nancy Stephens Donatelli, RN, MS, CEN, NE-BC question4gene@gmail.com