My exam 26-5

1.ACE inhibitors are used in the the treatment of: a.hypertension b.migraine
c.asthma d. all of the above
2.which one is not ca channel blocker : a.verapamil b.deltiazem c. amlodipine d.
cinnarzine
3.the conc of the drug on expiration date is:a.from 90-110% b.not less than 90% c.
not less than 100% d.not all the above
4.hepatitis vaccine does is: a.3 times/year

b. twice/year

c. once/year

5.bioavailability of the drug is :a. rate of absorption b.extent of absorption

and extent

c.rate

6. benzyl peroxide is used in trearment : a.acne vulgaris b. rheumatic pain b.

angina pectoris d. dysmenorrheal
7.for the treatment of anaphylactic shock use: a. salbutamol b.diphenhydramine c.
acetazolamide d epinephrine e. aminophylline
8.which of the following is not colloid solution: a. albumin b. ringer solution c.
dextran d.beta starch e. albumin
9.which of the following is released by bacterial infection: a.endotoxin b.exotoxin
c.antibiotics d. cytotoxin e. nonoof the above
10.which of the following are causes of edema: a.increase hydrostatic pressure b.
decrease oncotic pressure c. capillary permeability d. a,b and c
11.class ll antiarrythmic drugs produce its action through : a.decrease phase0
depolarization b.increase phase 3repolarization c.suppress phase 4 depolarization
d.adrenerdic receptor blocking e.shorten action potential
12.vitamin a daily dose for female : 700 microgram
13.bioavailability mean the drug reach a. site of action

b. blood circulation

14.which of the following statements describing first dose phenomen that prazosin
is true:
a.amarked increase in the level of glucose following the initial dose of prazocin
b. amarked decrease in the level of glucose following the initial dose of prazocin
c. amarked increase in the level of cholesterol following the initial dose of prazocin
d. amarked postural hypotension 30 to 90 following the initial dose of prazocin
15. 3- Enkephalins are peptides that:

a. have narcotic antagonist activity.

b. exert actions resembling those of opiates.
c. are found only in the central nervous system.
d. cause blood vessel wall relaxation.
e. transmit pain impulses
16. prep. contin
coal tar 30 part
petrolatum 15 part
adeq. to 150 part
what conc. of petrolatum in 500 ml: 700 coal tar petrolatum
17. anti cancer derived from venca is_
a_cyclophosamide
b_flourouracil
c_doxurubcin
d_ cicplastin
18. in tolerence
patient need more dose to obtain the same effect
19. Captopril and Enalapril do all the following except:
a- Increase rennin concentration in blood
b- Inhibit an enzyme
c- Competively blocks Angiotensin || at its receptorS
d- Raises the blood Potassium concentration
20. Various opiates may be used as all of the following except :
a- Analgesics
b- Anti-inflammatories
c- Antidiarreals
d- Aids to anesthesia
e- Antitussive
21. 0- for a 4 year old child, the maximum daily dose of paracetamol is
a- 240mg
b- 480 mg
c- 1 g
d- 2 g
22. To supply the myocardium with O2 shortly after myocardial infarction we give
a-anticoagulant
b-fibrinolytic
c-aspirin
d-ACEI
23.Cyclosporine is used for
a- allergies
b- angina

c- prevention of transplant rejection

d-steroids deficiency
e- treating lead poisoning
24. Tolerance is a problem when using Nitroglycerin, which of the following is true:
a- Tolerance doesn't occur in young patient
b- Over 50 years patient doesn't develop tolerance
c- Dosing schedule may affect tolerance
d- Isosorbide dinitrate doesn't develop tolerance
25. The following properties are similar for both solutions and suspensions:
A. The components of both solutions and suspensions can be separated from each
other by physical processes. .
8. Solutions and suspensions are composed of two or more components.
C. Solute in the solutions and suspensions settle out over a period of time.
D. Both A and B
E. Both Band C
26. Concerning COX-2 inhibitor, which is not true?
A. they have lower risk gastric adverse reactions than non-selective agents
B good evidence about their effectiveness in osteoarthritis
C. cardiac toxicity is a recent concern of this class of drugs
D. they are. usually administered once or twice daily
E. combination with non-selective agents provide additional benefit
27. the pharmacological property of amphetamine is:
A. Causes release of estrogen.
B. Causes release of stored norepinephrine.
C. Does not cross the blood brain barrier.
D. Causes the release of stored acetylcholine.
E. Metabolized by phosphodiesterase II.
28. Digoxin action except :a-+ve inotropic b-shorten refractory period in atrial and ventricular myocardial
c-increase conduction velocity in AV node
d-contraction of myocardial muscle
29. The Molal concentration of 0.559 M is (Mwt=331.23 g/mol& density of solution
=1.157g/ml) is:
a-1.882
b-0.882
c-0.559
d-0.575
30.drug container contain 90 mg each tablet contain 0.75mg. how many doses?
90 / 0.75 = 120 doses
31- has 5-HT antagonist and H1 antihistamine effects

Cyproheptadine
32- Dobutamine is used as :
a- Parasympathomimetic
b- In cardiac surgery
c- Hypotensive agent
d- All of the above
33- Controled released drug delivery depends on :
a- Body fluid interaction
b- Enzymatic reactions
c- Ready programmed & no influece of the body fluid
d- Stomach PH.
34- All of these are antichlonergic except :
a- Atropine sulphate
b- Hydroatropine
c- Mebeverine
d- Iprotropium bromide
e- Butrepium bromide
35.pharmacokinetics constant :
A.zero order
B.first order
C.mixed order
D.a and b
36.when you know the preservative used with the antibiotic is not suitable:
A.use another one suitable
B.add another to increase its activity
C.use two or more preservative may increase the activity and may become suitable
d.a and c
37.The action of histamine is : acapillary constriction
elevation of blood pressure cstimulation of gastric secretion dskeletal muscle paralysis
eslowing the heart rate

b-

38.Inderal is : asimilar in action to ergotamine bsimilar in action to tubocurarine cused as an antihistamine dpure badrenergic receptor blocker
39.The heart`s dominant pacemaker is : a AV node bSA node cpukinje fiber
dinternodal pathways enon of the above
40.The term shock signifies : ahyperperfusion bhypoperfusion ctachycardia dbradycardia
enon of the above
41.In treatment of shock , which of the following should be considered? aairway control
bIV of crystalloid solution cdopamine to support blood pressure dmonitor heart rhythm
eall of the above

42. A disease modifying drugs in rheumatoid arthritis: agold preparations bhydroxychloroquine cmethotrexate d a and b ea , b and c
43Which of the following is true about surgical prophylaxis ? ait is given to treat surgery associated infections bit is given to reduce the possibility of surgical site infection cshould always be given regardless type of surgery dshould be continued for 7 days after surgery eall are true
44When diagnosis of diabetes to be considered : aWBC count with differential boral glucose tolerance test
c HBA1c d a and b e b and c
45.These are non aqueous pharmaceutical solutions:
aotic soln. , mouth washes and nasal soln.
bessences , collodions an elixirs
cgargles , douches and irrigation soln.
dsyrups , mucillages and collodions
eenemas , liniments and spirits
46.Which of the following is NOT a primary literature agournal of pharmacy practice bapplied therapeutic & clinical use of drug cnew EnglandJournal of medicine dLoncet eJAMA
50 References to check compatibility of drugs in parentral administration: aMERCK Index bhandbook on injectable drugs
cmicromedix d a and b e b and c
51.When concidering drug therapy for hypertention , which is true? acombination of drugs always preferred bhydralazine is first line therapy in young hypertension cfurosemide should be administrated before meal to improve absorption dbetablokers should be avoided in asthmatic patient eACEIs are recommended in pregnant women
52.The antimalarial to be avoided in glucose6phosphate
dehydrogenase deficiency : aprimaquine bquinine cchloroguanide
53.Role of carbidopa in treatment of Parkinsonism. a$Serotonin reuptake
bdopamine agonist cDecrease dopamine in peripheral vessel d Dopamine antagonist
5HT1 antagonist

e-

54.When drug absorbed through GIT then go to liver and

excreted this process called a first pass bdrug metabolism c drug distribution
55.azaleic acid used in :
a.acne b.psoriasis
c myocardial infarction
56.monitoring for dose in elderly patient: aexcretion in kidney decrease
decrease in liver enzymes function creabsorption is high
dmetabolism is high e A ,b
57-

b-

which of the following cause metallic taste acaptopril bcimetidine

cmetoformin d-metronidazole
58. the optimal size for ophthalmic drops: < 10g
59.tegretol is used in the ttt of: tregimnal neuralgia , seizures
60.Drugused in ttt of traveler diarrhea: aampicillin
trimoxazole d ciprofloxacin

b amoxicillin c co-

61.drug used for ttt of migraine and HTN: aclonidine b minoxidil cpropranolol
hydralazin
62.determination analysis of solution depend on anature of solute
type of solution canalyzer d a.b

b-

64.when use liquid or oint. to dissolve the solid it is called : levigation

65. which of the following cause depression : reserpine
66.about cardioglycosidic effect : ave inotropic
Bradycardia

cHypertension dTachycardia e-

67.all factors affect on distribution of drug except : aTissue solubility bProtein binding cMolecular weight of drug dType enzyme response of metabolism
68. the equation that determine the acid & base degree is:
(BRONESTED EQUATION )
69class IV anti arrhythmia is: (verapamil)
70.alpha 2 agonist :decrease blood pressure

All questions from 400 , 300 and 120 questions

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d-