E00-E07

Chapter IV
Endocrine, nutritional and metabolic diseases
(E00-E90)
Disorders of thyroid gland
(E00-E07)

E00Congenital iodine-deficiency syndrome

Incl.:
endemic conditions associated with environmental iodine deficiency either directly or as a
consequence of maternal iodine deficiency. Some of the conditions have no current
hypothyroidism but are the consequence of inadequate thyroid hormone secretion in the
developing fetus. Environmental goitrogens may be associated.
Use additional code (F70-F79), if desired, to identify associated mental retardation.
Excl.:
subclinical iodine-deficiency hypothyroidism (E02)
E00.0Congenital iodine-deficiency syndrome, neurological type
Endemic cretinism, neurological type
E00.1Congenital iodine-deficiency syndrome, myxoedematous type
Endemic cretinism:

hypothyroid

myxoedematous type

E00.2Congenital iodine-deficiency syndrome, mixed type

Endemic cretinism, mixed type
E00.9Congenital iodine-deficiency syndrome, unspecified
Congenital iodine-deficiency hypothyroidism NOS
Endemic cretinism NOS

E01Iodine-deficiency-related thyroid disorders and allied conditions

Excl.:
congenital iodine-deficiency syndrome (E00.-)
subclinical iodine-deficiency hypothyroidism (E02)

E01.0Iodine-deficiency-related diffuse (endemic) goitre

E01.1Iodine-deficiency-related multinodular (endemic) goitre
Iodine-deficiency-related nodular goitre
E01.2Iodine-deficiency-related (endemic) goitre, unspecified
Endemic goitre NOS
E01.8Other iodine-deficiency-related thyroid disorders and allied conditions
Acquired iodine-deficiency hypothyroidism NOS

E02Subclinical iodine-deficiency hypothyroidism

E03Other hypothyroidism
Excl.:
iodine-deficiency-related hypothyroidism (E00-E02)
postprocedural hypothyroidism (E89.0)
E03.0Congenital hypothyroidism with diffuse goitre
Goitre (nontoxic) congenital:

NOS

parenchymatous
Excl.:

transitory congenital goitre with normal function (P72.0)

E03.1Congenital hypothyroidism without goitre
Aplasia of thyroid (with myxoedema)
Congenital:

atrophy of thyroid

hypothyroidism NOS

E03.2Hypothyroidism due to medicaments and other exogenous substances

Use additional external cause code (Chapter XX), if desired, to identify cause.
E03.3Postinfectious hypothyroidism
E03.4Atrophy of thyroid (acquired)
Excl.:
congenital atrophy of thyroid (E03.1)

E03.5Myxoedema coma
E03.8Other specified hypothyroidism
E03.9Hypothyroidism, unspecified
Myxoedema NOS

E04Other nontoxic goitre

Excl.:
congenital goitre:

NOS (E03.3)

diffuse (E03.3)

parenchymatous (E03.3)

iodine-deficiency-related goitre (E00-E02)

E04.0Nontoxic diffuse goitre
Goitre, nontoxic:

diffuse (colloid)

simple

E04.1Nontoxic single thyroid nodule

Colloid nodule (cystic)(thyroid)
Nontoxic uninodular goitre
Thyroid (cystic) nodule NOS
E04.2Nontoxic multinodular goitre
Cystic goitre NOS
Multinodular (cystic) goitre NOS
E04.8Other specified nontoxic goitre
E04.9Nontoxic goitre, unspecified
Goitre NOS
Nodular goitre (nontoxic) NOS

E05Thyrotoxicosis [hyperthyroidism]
Excl.:
chronic thyroiditis with transient thyrotoxicosis (E06.2)
neonatal thyrotoxicosis (P72.1)

E05.0Thyrotoxicosis with diffuse goitre

Exophthalmic or toxic goitre NOS
Graves disease
Toxic diffuse goitre
E05.1Thyrotoxicosis with toxic single thyroid nodule
Thyrotoxicosis with toxic uninodular goitre
E05.2Thyrotoxicosis with toxic multinodular goitre
Toxic nodular goitre NOS
E05.3Thyrotoxicosis from ectopic thyroid tissue
E05.4Thyrotoxicosis factitia
E05.5Thyroid crisis or storm
E05.8Other thyrotoxicosis
Overproduction of thyroid-stimulating hormone
Use additional external cause code (Chapter XX), if desired, to identify cause.
E05.9Thyrotoxicosis, unspecified
Hyperthyroidism NOS
Thyrotoxic heart disease (I43.8*)

E06Thyroiditis
Excl.:
postpartum thyroiditis (O90.5)
E06.0Acute thyroiditis
Abscess of thyroid
Thyroiditis:

pyogenic

suppurative

Use additional code (B95-B98), if desired, to identify infectious agent.

E06.1Subacute thyroiditis
Thyroiditis:

de Quervain

giant-cell

granulomatous

nonsuppurative
Excl.:

autoimmune thyroiditis (E06.3)

E06.2Chronic thyroiditis with transient thyrotoxicosis
Excl.:
autoimmune thyroiditis (E06.3)
E06.3Autoimmune thyroiditis
Hashimoto thyroiditis
Hashitoxicosis (transient)
Lymphadenoid goitre
Lymphocytic thyroiditis
Struma lymphomatosa
E06.4Drug-induced thyroiditis
Use additional external cause code (Chapter XX), if desired, to identify drug.
E06.5Other chronic thyroiditis
Thyroiditis:

chronic:
o

NOS

fibrous

ligneous

Riedel

E06.9Thyroiditis, unspecified

E07Other disorders of thyroid

E07.0Hypersecretion of calcitonin
C-cell hyperplasia of thyroid
Hypersecretion of thyrocalcitonin
E07.1Dyshormogenetic goitre
Familial dyshormogenetic goitre
Pendred syndrome

Excl.:
transitory congenital goitre with normal function (P72.0)
E07.8Other specified disorders of thyroid
Abnormality of thyroid-binding globulin

Haemorrhage
of thyroid
Infarction
Sick-euthyroid syndrome
E07.9Disorder of thyroid, unspecified

E10-E14
Diabetes mellitus
(E10-E14)
Use additional external cause code (Chapter XX), if desired, to identify drug, if druginduced.
The following fourth-character subdivisions are for use with categories E10-E14:

.0

With coma
Diabetic:

coma with or without ketoacidosis

hyperosmolar coma

hypoglycaemic coma

.1

Hyperglycaemic coma NOS

With ketoacidosis
Diabetic:
acidosis

without mention of coma

ketoacidosis
.2

With renal complications

Diabetic nephropathy (N08.3*)
Intracapillary glomerulonephrosis (N08.3*)
Kimmelstiel-Wilson syndrome (N08.3*)

.3

With ophthalmic complications

Diabetic:

.4

cataract (H28.0*)

retinopathy (H36.0*)

With neurological complications

Diabetic:

amyotrophy (G73.0*)

autonomic neuropathy (G99.0*)

mononeuropathy (G59.0*)

polyneuropathy (G63.2*)
o

.5

autonomic (G99.0*)

With peripheral circulatory complications

Diabetic:

gangrene

peripheral angiopathy (I79.2*)

.6

ulcer

With other specified complications

Diabetic arthropathy (M14.2*)
Neuropathic diabetic arthropathy (M14.6*)

.7

With multiple complications

.8

With unspecified complications

.9

Without complications

E10Type 1 diabetes mellitus

[See before E10 for subdivisions]
Incl.:
diabetes (mellitus):

brittle

juvenile-onset

ketosis-prone
Excl.:

diabetes mellitus (in):

malnutrition-related (E12.-)

neonatal (P70.2)

pregnancy, childbirth and the puerperium (O24.-)

glycosuria:

NOS (R81)

renal (E74.8)

impaired glucose tolerance (R73.0)

postsurgical hypoinsulinaemia (E89.1)
E11Type 2 diabetes mellitus

[See before E10 for subdivisions]

Incl.:
diabetes (mellitus)(nonobese)(obese):

adult-onset

maturity-onset

nonketotic

stable

non-insulin-dependent diabetes of the young

Excl.:
diabetes mellitus (in):

malnutrition-related (E12.-)

neonatal (P70.2)

pregnancy, childbirth and the puerperium (O24.-)

glycosuria:

NOS (R81)

renal (E74.8)

impaired glucose tolerance (R73.0)

postsurgical hypoinsulinaemia (E89.1)
E12Malnutrition-related diabetes mellitus
[See before E10 for subdivisions]
Incl.:
malnutrition-related diabetes mellitus:

type 1

type 2
Excl.:

diabetes mellitus in pregnancy, childbirth and the puerperium (O24.-)

glycosuria:

NOS (R81)

renal (E74.8)

impaired glucose tolerance (R73.0)

neonatal diabetes mellitus (P70.2)
postsurgical hypoinsulinaemia (E89.1)
E13Other specified diabetes mellitus
[See before E10 for subdivisions]
Excl.:
diabetes mellitus (in):

malnutrition-related (E12.-)

neonatal (P70.2)

pregnancy, childbirth and the puerperium (O24.-)

type 1 (E10.-)

type 2 (E11.-)

glycosuria:

NOS (R81)

renal (E74.8)

impaired glucose tolerance (R73.0)

postsurgical hypoinsulinaemia (E89.1)
E14Unspecified diabetes mellitus
[See before E10 for subdivisions]
Incl.:
diabetes NOS
Excl.:
diabetes mellitus (in):

malnutrition-related (E12.-)

neonatal (P70.2)

pregnancy, childbirth and the puerperium (O24.-)

Type 1 (E10.-)

Type 2 (E11.-)

glycosuria:

NOS (R81)

renal (E74.8)

impaired glucose tolerance (R73.0)

postsurgical hypoinsulinaemia (E89.1)

Chapter XIV
Diseases of the genitourinary system
(N00-N99)
Renal failure
(N17-N19)
Use additional external cause code (Chapter XX), if desired, to identify external agent.
Excl.:
congenital renal failure (P96.0)
drug- and heavy-metal-induced tubulo-interstitial and tubular conditions (N14.-)
extrarenal uraemia (R39.2)
haemolytic-uraemic syndrome (D59.3)
hepatorenal syndrome (K76.7)
hepatorenal syndrome

postpartum (O90.4)

prerenal uraemia (R39.2)

renal failure:

complicating abortion or ectopic or molar pregnancy (O00-O07, O08.4)

following labour and delivery (O90.4)

postprocedural (N99.0)

N17Acute renal failure

Incl.:
acute renal impairment
N17.0Acute renal failure with tubular necrosis
Tubular necrosis:

NOS

acute

renal

N17.1Acute renal failure with acute cortical necrosis

Cortical necrosis:

NOS

acute

renal

N17.2Acute renal failure with medullary necrosis

Medullary [papillary] necrosis:

NOS

acute

renal

N17.8Other acute renal failure

N17.9Acute renal failure, unspecified
N18Chronic kidney disease
Incl.:
chronic renal failure
Use additional code, if desired, to identify underlying disease.
Use additional code, if desired, to identify presence of hypertension.
N18.1Chronic kidney disease, stage 1
Kidney damage with normal or increased GFR ( 90 mL/min)
N18.2Chronic kidney disease, stage 2
Kidney damage with mild decreased GFR (60-89 mL/min)

N18.3Chronic kidney disease, stage 3

Kidney damage with moderately decreased GFR (30-59 mL/min)
N18.4Chronic kidney disease, stage 4
Kidney damage with severely decreased GFR (15-29 mL/min)
N18.5Chronic kidney disease, stage 5
End stage kidney disease:

in allograft failure

NOS

on dialysis

without dialysis or transplant

Renal retinitis (H32.8*)

Uraemic:

apoplexia (I68.8*)

dementia (F02.8*)

neuropathy (G63.8*)

paralysis (G99.8*)

pericarditis (I32.8*)

N18.9Chronic kidney disease, unspecified

Chronic renal impairment
Chronic uraemia NOS
Diffuse sclerosing glomerulonephritis NOS
N19Unspecified kidney failure
Incl.:
Renal insufficiency NOS

Uraemia NOS
Excl.:
kidney failure due to hypertension (I12.0)
uraemia of newborn (P96.0)