Beruflich Dokumente
Kultur Dokumente
Beta Psi, Nurse Specialist (research), Contractor, Genetics Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD
Beta Psi, Dr. May Rawlinson Distinguished Professor & Senior Scientist, Oregon Health & Science University, School of Nursing, Portland, OR
Professor, Division of Child and Family Nursing, Oregon Health & Science University, School of Nursing, Portland, OR
Associate Professor, Oregon Health & Science University, School of Nursing, Portland, OR
Beta Psi, Associate Professor, Oregon Health & Science University, School of Nursing, Portland, OR
Key words
Mammography, decision making, breast cancer
screening, breast screening, breast cancer,
family history, grounded theory, qualitative
research
Correspondence
Dr. Karen E. Greco, 8901 Wisconsin Ave.,
Building 8, Room 5105, Bethesda,
MD 20889-5105. E-mail: karen.greco@nih.gov
Accepted: October 17, 2009
doi: 10.1111/j.1547-5069.2010.01335.x
Abstract
Purpose: This studys purpose is to describe and explain how women 55 years
of age and older with a family history of breast cancer make screening mammography decisions.
Design: A qualitative design based on grounded theory. This purposeful sample consisted of 23 women 55 years of age or older with one more first-degree
relatives diagnosed with breast cancer.
Method: Open-ended interviews were conducted with 23 women 55 years of
age and older with a family history of breast cancer using a semistructured interview guide. Transcribed interview data were analyzed using constant comparative analysis to identify the conditions, actions, and consequences associated with participants screening mammography decision making.
Findings: Women reported becoming aware of their breast cancer risk usually due to a triggering event such as having a family member diagnosed with
breast cancer, resulting in women guarding against cancer. Womens actions
included having mammograms, getting health check-ups, having healthy behaviors, and being optimistic. Most women reported extraordinary faith in
mammography, often ignoring negative mammogram information. A negative mammogram gave women peace of mind and assurance that breast cancer
was not present. Being called back for additional mammograms caused worry,
especially with delayed results.
Conclusions: The guarding against cancer theory needs to be tested in other
at-risk populations and ultimately used to test strategies that promote cancer
screening decision making and the adoption of screening behaviors in those at
increased risk for developing cancer.
Clinical Relevance: Women 55 years of age and older with a breast cancer
family history need timely mammogram results, mammography reminders,
and psychosocial support when undergoing a mammography recall or other
follow-up tests.
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Greco et al.
breast cancer, compared to women without this family history. Breast cancer risk can quadruple with two
or more first-degree relatives diagnosed with the disease
(ACS).
Mammography is currently the most effective method
for reducing breast cancer mortality and detecting the
disease when cure is most likely (United States Preventative Services Task Force, 2002; Nystrom et al., 2002).
Despite considerable research related to factors associated with mammography use and interventions to increase utilization, in a large study of women 40 years
of age and older, 35% of women reported no mammogram in the past 2 years. In addition, there was an alarming 3.5% decline in mammography use from 2000 to
2005 (Slomiany, McMasters, & Chagpar, 2008). According to a meta-analysis, healthcare provider recommendation is consistently associated with increased mammography use (Schueler, Chu, & Smith-Bindman, 2008);
however, as a womans age increases, the likelihood that
her physician will recommend mammography decreases
(Hawley, Earp, OMalley, & Ricketts, 2000; Lane, Zapka,
Breen, Messina, & Fotheringham, 2000).
Having a family history of breast cancer impacts breast
cancer risk perception, early detection beliefs, and mammography decisions, although study results are inconsistent. In women 40 years of age and older without breast
cancer, those with a first-degree relative with the disease
were more likely to believe breast cancer could be cured
with early detection. They were also more likely to report
a mammogram within the past year and rate their breast
cancer risk higher than women without a family history
(Tracy et al., 2008). In another study, however, 89% of
women with a high breast cancer risk due to family history and other risk factors had an optimistic bias and underestimated their breast cancer risk. Level of perceived
risk did not correlate with breast cancer screening in this
study (Katapodi, Dodd, Lee, & Facione, 2009).
In a study of 41 women 27 to 84 years of age, 12 with
a breast cancer family history, Silverman et al. (2001)
explored womens beliefs about breast cancer and mammography. Almost all women viewed breast cancer as a
progressive disease that begins in a silent curable form.
Most believed that mammography had no down sides
and could detect breast cancer early, and that breast cancers were seldom missed. Women believed even benign
lesions had malignant potential.
A similar qualitative study of 50 women 36 to 83 years
of age identified three approaches to mammography decision making (Lewis, Corcoran-Perry, Narayan, & Lally,
1999). Nearly half the women used thoughtful consideration considering age, family history, breast cancer risk
factors, and mammography risks and benefits, with 57%
having mammography. A third used cursory consider-
Methods
Design
Grounded theory methodologies guided this qualitative study. The study design was emergent, allowing the
inquiry methods to be adapted based on what was
learned in the ongoing data analysis. Using inductive
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Sample
Twenty-three women 55 to 85 years of age (Table) living independently participated in this study. Ten of the
women were married at the time of the interview, and
all had at least a high school education, with 11 having
some college. No participants used mobility aids. Participants had a total of 31 first-degree relatives with breast
cancer (10 mothers, 15 sisters, and 6 daughters) and an
average of 3.2 first- or second-degree relatives diagnosed
with any cancer.
Data Analysis
Data collection and analysis occurred simultaneously
since data analysis guided further data collection. Data
were analyzed using text coding strategies common to
grounded theory. Concepts were identified through open
coding and organized into categories based on how
well they explained mammography decision-making processes. Comparative analysis was used to identify patterns
and variations in the data. Axial coding was conducted
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Greco et al.
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8
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5
12
11
10
4
7
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that identified conditions, actions, and consequences associated with the core category or main theme in the
womens stories. Theoretical sampling was used to help
develop the concepts and categories, for example, to gain
understanding of how the two women who were not
having mammograms guarded against cancer. Theoretical memos documented the researchers thoughts and
ideas during analysis. A theoretical model was developed
that explains how older women with a family history of
breast cancer make screening mammography decisions
(Figure).
While the principal investigator conducted all of the interviews and did the preliminary analyses, three coinvestigators reviewed segments of the interview data, coding,
and theoretical memos and provided critical feedback on
how the data were conceptualized. Disagreements about
the meanings of data or codes were resolved by reaching consensus in understanding the participants interview responses. Several research participants were interviewed a second time to answer additional questions to
help refine the theory and to comment on whether the
emerging theory and framework represented their experience, and changes were made based on this feedback.
Trustworthiness of the grounded theory was verified
by conducting multiple interviews with five participants, sharing and discussing the data and codes with
coinvestigators, and using an audit trail for external review of field notes and theoretical memos.
Greco et al.
Results
Guarding Against Cancer Grounded Theory
The guarding against cancer theory describes and explains the conditions, actions, and consequences involved
when women 55 years of age and older with a family
history of breast cancer make decisions about whether or
not to have screening mammography. Guarding against
cancer was the core process emerging from the data used
to name the theory (Figure). Conditions associated with
the decision-making process include triggering events,
being aware of risk, and beliefs. Actions women took in
guarding against cancer included taking charge of health
and maintaining faith. The consequences or outcomes of
guarding against cancer were how much peace of mind
and assurance women had that cancer was not present
and how much worry women had about cancer.
The process of guarding against cancer was usually the
result of a triggering event that caused participants to
become aware of their breast cancer risk. Women talked
about their fear of getting breast cancer, dying of breast
cancer, or having it and not knowing it. Women varied
in how much they were guarding against cancer. As one
woman put it, you might sometimes be on real rigid,
scared, on guard and other times you might be lightly on
guard. Triggering events usually caused women to increase or evaluate their level of guarding against cancer.
Greco et al.
participants receiving mammography who reported regular healthcare provider visits reported no recent clinical
breast examination.
The two women who reported they were not receiving regular mammograms both believed mammograms
were effective; however, they had different reasons for
not having mammograms. Both were in their eighties and
believed they were at risk for breast cancer, although they
believed their risk was lower than it was 20 to 30 years
ago. Both women had two first-degree relatives diagnosed with breast cancer, one of whom was a daughter.
One woman guarded against cancer by avoiding mammograms because she believed they could actually cause
her to have breast cancer. She had received painful mammograms in the past and reported telling a technician,
Every time you guys do this you press so hard, if I dont
have cancer now, I will when you get through. The
other woman reported not having had a mammogram
in at least 20 years because, although she reported receiving annual physical examinations, her doctor hadnt
given her a breast examination in years or recommended
a mammogram, so she believed she must not need them.
She also believed her breast cancer risk was lower in
her eighties because both her mother and daughter had
been diagnosed with breast cancer in their fifties. She was
guarding against breast cancer by checking her breasts
several times a week in the shower, watching for any
signs and symptoms, and being careful about her diet.
Greco et al.
Discussion
In this study, conditions facilitating womens decisions
to have mammography included having a family member
diagnosed with breast cancer, believing that mammography detects breast cancer early, believing increased age
increases breast cancer risk, receiving mammography reminders, and having a healthcare provider recommend
a mammogram. Participants reported physician recommendation as influencing their decision to have a mammogram, which is consistent with the literature. What
was not found in the literature was women being willing to defy their healthcare providers, if needed, to have
their mammograms.
Although in this study participants described being actively involved in mammography decision making, in a
study by Burack, George, and Gurney (2000), age was
inversely related to active involvement in mammography decision making ranging from 48% in women 55 to
59 years of age to 19% in women 75 years of age and
older. Perhaps women with a breast cancer family history are more likely to be actively involved because they
are more aware of their breast cancer risk.
Not having insurance coverage has been associated
with lower mammography rates, although, even with
Medicare, older women are less likely to receive mammography (Schueler et al., 2008). All participants in
this study had insurance coverage. Women on Medicare, however, reported needing to track their mammography dates in order for Medicare to cover the
cost.
Increased age may be under recognized as a breast
cancer risk factor in women with a breast cancer family history and patient education may be needed. Some
women in this study believed as they got older breast
cancer risk was reduced and screening was less important. In an earlier study, 12% of older women did
not recognize increased age as a breast cancer risk factor (Thomas, Fox, Leake, & Roetzheim, 1996). More
current studies related to whether or not women recognize age as a breast cancer risk factor were not
found. However, a recent study found age was inversely
related to womens level of perceived breast cancer risk
regardless of family breast cancer history (Katapodi et al.,
2009).
Individuals at increased risk for cancer may share
core experiences related to undergoing cancer screening
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Greco et al.
Study Limitations
All participants were White women. Most participants had multiple first-degree and second-degree relatives with breast and other cancers. Their mammography decision-making processes may be different from
women with only one first-degree relative with breast
cancer, or women from ethnically diverse backgrounds.
The accuracy of self-reported mammograms could not
be verified with medical records. Although efforts were
made to recruit women not receiving regular mammograms, only two participants were not receiving regular
mammograms.
Conclusions
Findings from this study indicate that primary care
providers can facilitate women 55 years of age and older
deciding to have mammograms by providing mammogram reminders, timely mammogram results, and psychosocial support for women undergoing a mammography recall or other follow-up tests such as ultrasound
or breast biopsy. Healthcare providers also need to inform women that breast cancer risk increases with age
because some women may believe as they get older their
breast cancer risk lowers and breast cancer screening is
not needed, especially if their relative was diagnosed with
breast cancer at a younger age.
Studies are needed to identify support needs of women
with a breast cancer family history undergoing mammography recall, the impact of delay in receiving mammography results, and to compare psychological and cost
outcomes in women who receive care in centers where
follow-up tests can be done the same day compared with
settings where test results are delayed. Researchers need
to explore older womens beliefs about age and breast
cancer risk and the relationship to mammography behavior. Findings from this study need to be compared
to a larger sample of older women not receiving regular
mammography and to the mammography decisionmaking processes of different ethnic groups. The guarding against cancer theory needs to be tested in other
at-risk populations such as those at increased risk for colorectal cancer. Developing a more generalizable theory
can be used in future studies to test strategies that promote cancer screening decision making and the adoption of screening behaviors in those at increased risk for
developing cancer.
Acknowledgments
The primary author would like to acknowledge support from the following funding sources: John A.
Greco et al.
Hartford Foundations Building Academic Geriatric Nursing Capacity 20022004 Pre-Doctoral Scholarship; National Institutes of Health National Research Service
Award for Research Training: Nursing Care For Older
Populations (T32 NR0007048); National Institutes of
Health National Research Service Award for Research
Training: Nursing Care For Older Populations (T32
NR7048-15); Oregon Health & Science University Deans
Scholarship; and Oncology Nursing Foundation 2002
Doctoral Scholarship. The authors would also like to acknowledge Richard J. Greco for his assistance with the
guarding against cancer diagram in the Figure.
Clinical Resources
r National Cancer Institute Screening Mammograms.
http://www.cancer.gov/cancertopics/factsheet/
detection/screening-mammograms
National Comprehensive Cancer Network Guidelines for Breast Cancer Screening. http://www.
nccn.org/professionals/physician gls/f guidelines.
asp
Susan G. Komen for the Cure Breast Cancer
Screening and Mammography Resources. http://
ww5.komen.org/breastcancer/earlydetectionamp
screening.html
U.S. Surgeon Generals Family History Initiative
Resources and downloadable Pedigree Forms.
http://www.hhs.gov/familyhistory/respachealth.
html
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