BIOL 350: General Microbiology

Exam 3
VERSIONB

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1.Helicobacterpyloriisassociatedspecificallywithwhatdisease?
A. stomachulcers.
B. coloncancer.
C. diarrhea.
D. foodpoisoning.
E. meningitis

2.BacteriavirulencefactorsthataregroupedtogetherandtypicalhavealowerGC
contentcanbefoundonwhichofthefollowingelements?
A. pathogenicityislands.
B. plasmids.
C. transposons.
D. bacteriophage.
E. alloftheabove
3.Whichorganismthatisresponsiblefordangerousoutbreaksisresistantto
almosteveryantibiotictherapy?
A. Streptococcuspneumoniae.
B. Neisseriameningitidis
C. Helicobacterpylori.
D. Vibriocholerae.
E. Klebsiellapneumoniae.

4.Whichstructurelargelyhelpsabacteriumavoidphagocytosis?
A. capsule
B. flagella
C. peptidoglycan
D. Slayer
E. pili
5.Whichofthefollowingarebacterialvirulencefactorsthatcancreateachannel
inhostcellmembranescausingthehostcelltolyse?
A. pathogenicityislands
B. pili
C. invasins
D. toxins
E. alloftheabove
6.Staphylococcusaureusthatisresistanttomultipleantibioticssuchas
methicillinencdodesanalternativePenicillinBindingProteinencodedonwhich
mobilegeneticelement?
A. plasmid
B. transposon
C. bacteriophage
D. pathogenicityisland

E. noneoftheabove
7.Anantibioticwhichpreventsgrowthoftheorganismisconsideredtobewhat?
A. bactericidal
B. broadspectrum
C. narrowspectrum
D. bacteriostatic
E. alloftheabove
8.Whichprocessofthebacterialcellservesasanidealtargetforantibiotic
therapy?
A. cellwallsynthesis
B. DNAreplication
C. proteinsynthesis
D. Transcription
E. alloftheabove
9.WhichofthefollowingdoesNOTcharacterizeInnateimmunity?
A. involveshighlyspecializephagocyticcells
B. animportantfirstlineofdefense
C. recognizesPAMPs
D. characterizedbylonglivedspecificmemory
E. utilizesantimicrobialpeptides

10.WhichofthefollowingisconsideredaPAMPthatisrecognizedbytolllike
receptors?
A. lysozyme
B. antimicrobialpeptides
C. peptidoglycan
D. TTSS
E. alloftheabove
11.Whichisthekeycomponentinextracellulartrapswhichensnaresthe
bacteria?
A. antimicrobialpeptides
B. lysozyme
C. DNA
D. pili
E. neutrophils
12.Theantibacterialactivityoftheantibioticshownaboveisconferredbywhich
importantcomponent(depictedbyarrow)?
A.Thiazolidine

B. Betalactamase
C. Betalactamring
D. DalaDalapeptide
E. Nacetylglucosamine
3.Tetracyclineworksbywhichprocess?
A. Bindstheribosomallargesubunittoblocktransferofpeptides
B. Prevent30sand50sribosomalsubunitsfrombindingeachother
C. Competitiveinhibitorofcrosslinktranspeptidation
D. BindsthesmallribosomalsubunittoblockbindingofaminoacyltRNA
E. B&D

14.VirulencefactorsinBacillusanthracisareencodedonwhichmobilegenetic
element?
A. plasmid
B. transposon
C. bacteriophage
D. pathogenicityisland
E. A&Bonly

15.Spontaneousmutationsmayresultinwhichformofantibioticresistance
acquisition?
A. destroyingtheantibiotic
B. modificationoftheantibiotic
C. drugeffluxpump
D. modificationofantibiotictarget
E. alloftheabove
16.WhichformofAnthraxinfectioninthemostdeadly?
A. Inhalational
B. Cutaneous
C. Oropharyngeal
D. Gastrointestinal
E. alloftheabove
17.Whichbacteriumthatcausesmeningitisdoessoprimarilyinnewborns?
A. Streptococcuspneumoniae
B. Hemophilusinfluenzae
C. Neisseriameningitidis
D. GroupBstreptococcus
E. Listeriamonocytogenes
18.Forwhichbacteriumthatcausesmeningitisisthereahighlyeffectivevaccine?

A. Streptococcuspneumoniae
B. Hemophilusinfluenzae
C. Neisseriameningitidis
D. GroupBstreptococcus
E. Listeriamonocytogenes

19.Whichmineralisbeingusedtohelpcurediarrhea?
A. Chloride
B. VitaminB
C. Iron
D. Mercury
E. Zinc

20.Whatisthecorrectorderoftheeventsinphagocytosis?
1)Dischargeofwastematerial;2)Fusionofthephagosomewithalysosome;3)
Adherenceofthemicrobetophagocytes;4)Digestionofingestedmicrobe;5)
Formationofaphagosome;6)Ingestionofmicrobebyphagocyte.
A. 3,6,5,2,4,1
B. 3,4,6,5,2,1
C. 6,5,2,4,3,1
D. 5,2,3.6,4,1
E. 6,3,5,4,2,1
21.WhatistrueofCryptophyteAlgae?
A.Theyallhavechoroplasts
B.Theyhavetwonuclei
C.Theymoveusingpseudopods
D.Alloftheabovearecorrect
E.AandBarecorrect
22.Whichofthefollowingdescribesthesymbioticrelationshipknownasa
mutualism?
A.bothspeciesbenefitinanunspecificmanner
B.onespeciespreysuponanother
C.onespeciesbenefitswhiletheotherisharmed
D.onespeciesbenefitswhiletheotherisunaffected
E.bothspeciesbenefitanddependoneachother

23.WhatisTRUEaboutdeepseathermalventecosystems?
A.Mostofthediversityisinsidetubeworms

B.Theyhavemanyhalophiles
C.Detritusistheirmaincarbonsource
D.Alloftheabove
E.Noneoftheabove
24.WhichofthefollowingisthemajorPRODUCERinterrestrialecosystems?
A.Nitrogenfixingbacteria
B.Plants
C.Fungi
D.Bacteria
E.Protists
25.WhatisTRUEofthehumangenitourinarymicroflora?
A.Lactobacilluscanpreventestablishmentofpathogens
B.Propionbacteriaareabundantinthismicroflora
C.Healthybladdersarefullofbacteria
D.ThemicrofloraneedstotoleratehighpH
E.Noneoftheabove.

26.WhatisTRUEabouttheintestineanditsmicroflora?
A.ThelowpHofimpedesbacterialgrowth.
B.Thevastmajorityofhumanassociatebacterialivehere.
C.Streptococcusaredominanthere.
D.Helicobacterpyloricommonlyinfectintestinewalls.
E.Itselectsforsalttolerantbacteria.
27.Bacteroidesthetaiotaomicronisimportanttohumanhealthbecauseit:
A.PreventsHelicobacterestablishment
B.Helpsdigestfoodinthestomach
C.Helpsbreakdowncomplexcarbohydrates
D.Alloftheabove
E.Noneoftheabove

28.Whichofthefollowingispartoftheskinconditioncalledacne:
A.Apathogenicmicrobeinvadesthehairfollicle
B.Thecausalagentfeedsonhormonesreleaseinpuberty
C.Thecausalagentisfoundonnormalhealthyskin
D.Alloftheabove
E.Noneoftheabove
29.Skinisdifficulttocolonizebecause:
A.ThehighpH
B.Ittendstohavelowmoisture
C.Staphylococcusepidermiskeepsoutotherbacteria
D.Skinisonlyabletobecolonizedinpuberty
E.Alloftheabove

30.Africansleepingsicknessiscausedbya:
A.ATrypanosome
B.Giardia
C.Paramecium
D.AnAmeobozoan
E.Noneoftheabove

TRUEorFALSEquestions
31.Synergismisaspecificinteractionwherebothpartnersbenefit.
A.True
B.False
32.Themouthhasthehighestproportionofanaerobesofanyhumanmicrobial
ecosystem
A.True
B.False
MATCHINGQUESTIONS:
Questions3336:MatcheachofthefollowingitemswiththeBESTmatchbelow.Only
oneanswerperquestion,butalettermaybeusedmorethanonceornotatall.
(A)Barophilic
(B)Benthos
(C)Neuston
(D)Aeratedhorizon
B33. Watercontactsoceanfloor
A34.Loveshighpressure
C35.Airwaterinterface
D36.Decomposedmaterial
Questions3740:MatcheachoftheorganismswiththeBESTmatchbelow.Onlyone
answerperquestion,butalettermaybeusedmorethanonceornotatall.
(A)Yeast
(B)BrownAlgae
(C)Basidiomycetes
(D)Ciliates
B37. Energystoragelipid
C38.Fruitingbody
D39.RNAmadeinMacronucleus
C40.Gametesfuse,butnotnuclei

BIOL 350 Exam 3 Fall 2010