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Abstract
Resumen
Keywords
Palabras clave
Prevention of urinary tract infection
New preventive measures for the urin
Conclusion
Conflict of interest
References
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doi:10.1016/j.acuroe.2011.05.001
Refers To
Abstract
Context
This article reviews diverse aspects of the prevention of urinary tract infections, including
confirmation of the diagnosis, application of hygiene and dietary measures, antibacterial
prophylaxis (preferably consisting of a single nocturnal oral dose per day of an antibiotic or
drug with high urinary excretion and good tolerance), and administration of vaccines made
with Escherichia coli and other Gram-negative bacilli, consisting of immunostimulating
fractions of E. coli strains or E. coli type-1 fimbriae administered through the parenteral or
oral route.
Objective
We aimed to review the new preventive measures against urinary tract infections.
Acquisition and synthesis of evidence
We reviewed various microbiological aspects, as well as the physiopathology and virulence
factors of uropathogenic E. coli strains expressing type-1 and P fimbriae. The association
between blood groups and urinary tract infections in blood group antigen-secretors and
nonsecretors was analyzed.
Conclusions
New preventive measures against urinary tract infection consist of the use of phenolinactivated vaccines administered via the mucosal route, inhibitors of bacterial adherence
and biofilm formation, and cyclic adenosine monophosphate stimulators, especially in
women aged between puberty and menopause, who show the highest incidence of these
infections.
Resumen
Contexto
En este artculo se revisan diferentes aspectos acerca de la prevencin de las infecciones
del tracto urinario que incluyen: la confirmacin de la existencia de dichas infecciones, la
aplicacin de medidas higinico-dietticas, la profilaxis antibacteriana preferentemente
la toma de una nica dosis nocturna diaria oral de un antibitico o quimioterpico con
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Keywords
Urinary infection; Adherence; Fimbriae; Biofilms; Vaccines
Palabras clave
Infeccin urinaria; Adherencia; Fimbrias; Biopelculas; Vacunas
Corresponding author.
Copyright 2011 AEU. Published by Elsevier Espaa S.L. All rights reserved.
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