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5.
c. Anti-Ro/SSA antibodies
d. Anti-SCL70 antibodies
e. Rheumatoid factor
Which of the following is a pro-inflammatory
cytokine?
a. CRP
b. Interleukin 4 (IL-4)
c. IL-10
d. Serum amyloid precursor protein
e. Tumour necrosis factor-alpha
6. A 72-year-old man presents with an acutely painful
right knee. On examination, he had a temperature
of 37C with a hot, swollen right knee. Of relevance
amongst his investigations, was his white cell count
which was 12.6 109/l and a knee X-ray revealed
reduced joint space and calcification of the articular
cartilage. Culture of aspirated fluid revealed no growth.
What is the most likely diagnosis?
a. Gout
b. Psoriatic monoarthropathy
c. Pseudogout
d. Rheumatoid arthiritis
e. Septic arthritis
7. Which of the following regarding Infliximab is
most true?
a. Is a monoclonal antibody to the glycoprotein
IIb-IIIa receptor
b.
Is authorized for the treatment of severe
ulcerative colitis
c. Is licensed for the treatment of RA
d. It prevents relapse of Crohns disease in patients
who are in remission
e.
Must not be used in combination with
methotrexate due to increased toxicity
8. A 25-year-old lady with known systemic lupus
erythematosus (SLE) presents with the nephrotic
syndrome. A renal biopsy is performed and this
confirms diffuse proliferative glomeronephritis (WHO
Class IV). Which of the following treatment regimens
would you advise?
a. Azathioprine alone
b. Prednisolone alone
c. Azathioprine and prednisolone
d. Prednisolone and intravenous cyclophosphamide
e. Prednisolone and methotrexate
March 2014 | Vol 19 | Issue 1
81
Answers