RAJIV GANDHI UNIVERSITY OF HEALTH SCIENCES,

BENGALURU, KARNATAKA
COMPLETED PROFORMA FOR REGISTRATION OF SUBJECT
PANCHAKARMA FOR DISSERTATION IN M.D. (AYURVEDA)
A COMPARITIVE CLINICAL STUDY ON NASYAKARMA IN
VISHWACHI WITH AND WITHOUT GREEVA BASTI W.S.R. TO
CERVICAL SPONDYLOSIS
By

VANISHREE AITHAL
1ST YEAR M.D
DEPT. OF POST GRADUATE STUDIES IN PANCHAKARMA,
MUNIYAL INSTITUTE OF AYURVEDA MEDICAL SCIENCE ,MANIPAL ,KARNATAKA
GUIDE

DR. CHETAN KUMAR.M.D.(AYU)

READER,
DEPT.OF PANCHA KARMA,
MUNIYAL INSTITUTE OF AYURVEDA MEDICAL SCIENCE ,MANIPAL ,KARNATAKA.
CO GUIDE

DR. GURUPRASAD SHETTY. M.D.(AYU)

ASST.PROFESOR ,
DEPT.OF PANCHA KARMA,
MUNIYAL INSTITUTE OF AYURVEDA MEDICAL SCIENCE , MANIPAL, KARNATAKA.

2012 - 2013
MUNIYAL INSTITUTE OF AYURVEDA MEDICAL SCIENCE
MANIPAL 576104, KARNATAKA.

ANNEXURE II
1. NAME OF THE
CANDIDATE
AND ADDRESS

VANISHREE AITHAL
DEPARTMENT OF POST GRADUATE STUDIES IN
PANCHAKARMA,
MUNIYAL INSTITUTE OF AYURVEDA MEDICAL
SCIENCE ,MANIPAL 576104, KARNATAKA..
W/O MAHESH AITHAL

PERMANENT ADDRESS

VISHWALEELA VAKWADY,
KUNDAPURA TALUK, UDIPI DIST,576257
KARNATAKA.

2. NAME OF THE
INSTITUTE

MUNIYAL INSTITUTE OF AYURVEDA MEDICAL

SCENCE, MANIPAL 576104, KARNATAKA.

3. COURSE OF STUDY AND

M.D. (Ayu.) PANCHAKARMA

SUBJECT
4. DATE OF ADMISSION

18-10-2012

TO THE COURSE
5. TITLE OF THE
DISSERTATION

A COMPARATIVE CLINICAL STUDY ON NASYA

KARMA IN

VISHWACHI WITH OR WITHOUT

GREEVABASTI
SPONDYLOSIS

W.S.R.

TO

CERVICAL

6) BRIEF RESUME OF THE INTENDED STUDY:

6.1) NEED FOR THE STUDY:
Present day lifestyle has led to many diseases which though doesnt kill the person, but
hampers the day-to-day life. One of such disease is Vishwachi, affecting the upper limbs.
Vishwachi is one of the most common type of Vatavyadhi found in clinical practice, in
which the Prakupitha Vata affects Kandara of Bahu1. It is a disorder which is prevalent in
the most active period of life. Being a Shoola Pradhana nanatmaja Vyadhi 2, it deprives the
patients of their ability to perform movements of upper limb, which inturn makes them
unable to carry their routine work. In modern parlance the above condition is described in
which radiating pain is experienced from the cervical region to the upper limb known as
cervical spondylosis. It is a common disease affecting the middle and old age group of both
sex and prevalent worldwide. Life time incidence of cervical spondylosis is said to be 4060%3.
In most of the yurvedic literature while explaining the Phalashruti of Taila yoga Acharyas
have said that taila mitigates the Vata at the same time it doesnt increases the Kapha 4 and
by considering Dalhan,s opinion in parlance to Gridhrasi and Vgbhats consideration
of beneficial effects of Nasya as Ghanonnata Skandha and Grva5, ksheera bala taila6 nasya
karma has been taken for the study.
Also Snehana and Swedana are conisdred as samanya chikitsa for any vata vyadhi by both
Acharya Vagbahata7 and Acharya Charaka8. Greeva basti is having the effects of both
snehana and swedana and it is considered as snehayukta sweda, hense it has been taken for
the study.

6.2) REVIEW OF LITERATURE:

Nidana similar to that of Samanya Vata Vyadhi9.

Samprapthi, Lakshanas10 and Chikitsa of vishwachi are mentioned by different

Acharyas.

Treatment measures of Samanya Vata Vyadhi are the measures for vishwachi also7.

Review of such conditions mentioned in contemporary medical science will be

undertaken. Relevant journals, periodicals, magazines, books and research conducted
at different research centres will also be reviewed.

Previous research works Done:

1

HEBBAR S,A study on manyastambha w.s.r. to its management by nasya,Govt. Ayurvedic

Medical College,Mysore, RGHUS, (1992)

SHALIGRAM S D ,A study of Astigata-vata w.s.r. to cervical spondylosis and role of

Snehana and Nasya Karma in its management, Gujrat Ayurveda University, Jamnagar,
(1998).

JAIN SUJNAN,A clinical study in the effect of mahamasha thaila nasya karma in vishwachi,
S D M College of Ayurveda, Udupi,RGHUS, (2004)

HIREMAT MUKTA,Evaluation of comparative efficacy of greevabasti and nasya karma

with karpasastyadi thailam in manya stambha, Gadag,RGHUS, (2006)

SHETTY GURUPRASAD,The effect of sahacharadi thailam nasya karma in vishwachi,

Alvas Ayurveda Medical College, Moodbidri,RGHUS,(2007)

6.3 OBJECTIVES OF THE STUDY:

a) To evaluate the effect of Nasya karma with ksheerabala taila in the management of
vishwachi.
b) To evaluate the effect of Nasya karma and Greeva basti with ksheerabala taila in the
management of vishwachi.
c) To compare the effect of Nasyakarma without Greeva basti and Nasya karma with Greeva
basti in the management of Vishwachi.

7. MATERIALS AND METHODS:

7.1 SOURCE OF DATA:

(a) Subjects:
Patients with classical features of vishwachi will be selected from O.P.D and I.P.D of
Muniyal Institute of Ayurveda Medical Science, Manipal.
(b) Literary:
Literary aspect of study will be collected from classical Ayurvedic and Modern text books
& will be updated with recent medical journals and internet.

(c) Selection of drugs:

The trial drugs will be collected from the source after proper identification.
(d) Preparation of the medicine:11
Ingredients of the Medicine:
Kalka dravya: Bala mula twak- 5 pala.This is made into paste by pounding with milk.
Sneha dravya: Tila taila 1 Prasta.
Drava dravya: Gokshira- 4 Prasta.
Preparation of taila
Taila will be prepared by following the classical method at Muniyal Ayurveda
Pharmacy,Manipal

7.2

METHOD OF COLLECTION OF DATA :

(a) Study design:

A single blind comparitive clinical study, in which 40 patients (including both groups) will be
selected on the basis of simple randomized sampling procedure according to inclusive criteria.
Sl.NO.

Procedure

Drugs

Duration

Quantity

Temperature

1.

Group A-

Ksheerabala

8 drops

Luke warm

Nasya

taila

(nasyakarma)

Karma
2.

Group BNasya karma

Ksheerabala

30 min

taila

(greeva

with Greeva

8 drops

48 degree
celsius

basti)

basti

(b) Inclusion criteria:

1. Patients suffering from classical signs and symptoms of vishwachi will be selected.
2. Patient fit for Nasya Karma.
3. Patients with positive physical sign.
4. Patients in between 18yrs and 70yrs of age will be selected.
5. Patients of either sex will be selected.
(c) Exclusion criteria:
1. Patients who are traumatic,infective and having neoplastic conditions of the spine.
2. Patients who are unfit for nasyakarma and greeva basti.
3. Any other systemic disorders which will interfere the treatment.

(d) Diagnostic criteria:

Diagnosis will be purely based on Pratyatma lakshana of vishwachi.

Positive x-ray findings ( Narrowing of the space between the intervertebral discs, bamboo
shaped lumbar spine, osteo-phytic lipping).

(e) Treatment plan:

Patients will be assigned into two groups consisting of

20 patients in each group

suffering from vishwachi. Both the groups will be given stanika abhyanga with ksheerabala taila
as a Pre-operative procedure for 5 min.

Group A: 20 patients of this group will be given only Nasya karma with kheerabala
taila .

Group B: 20 patients of this group will be given Greeva basti and Nasya karma with
ksheerabala taila.

Both the groups will be treated for a period of 7 days on IP basis after getting the written
consent.
(f) Posology:
Nasya karma (matra- 8 drops in each nostril)12
.

(g) Follow up and Duration (Both A & B Group):

The patients will be followed up at regular intervals of 7 days after treatment for a period
of 30 days.
(h) Assessment criteria:

The subjective and objective parameters of pre and post treatment will be compared for
assessment of the results. Then all the results will be analysed statistically.
Subjective parameters:

Stambha

Stambha grading

Score

No stiffness

25% impairment in the range of movement

not affecting daily routine work.

25-50% impairment in the range of

movement not affecting daily routine work

with difficulty
50-75% impairment in the range of

movement not affecting daily routine work

More than 75% impairment in the range of
movement not affecting daily routine work

Rukh

Rukh(Pain) grading

Thodha

Aruchi

Tandra

Gaurava

Score

Frequent Pain

Pain after exertion

No

Objective parameters:

Tenderness

Deep tendon reflexes

Score
Deep tendon reflexes grading

Muscle tone

Absent

Present

Brisk

Very brisk

Clonus

Muscle Tone grading

Score

No Increase

Slight Increase with catch and release

Minimum resistance through range

following catch
More marked increased tone through

range of movement
Considerable increase in tone. no

passive movement
Afflicted part rigid

Statistical analysis:
The observations will be analyzed critically and scientifically by employing statistical
tests,that is between the groups with unpaired t -test and also within the group with paired
t-test.
7.3. DOES THE STUDY REQUIRE ANY INVESTIGATION OR INTERVENTION TO
BE CONDUCTED ON PATIENT OR OTHER HUMANS OR ANIMALS? IF SO PLEASE
DESCRIBE BRIEFLY.
The study will be conducted clinically. No animal experimentation will be carried out.

Investigations: For diagnostic purpose (if necessary)

Blood Investigation : Hemoglobin gm%, Total WBC Count, Differential WBC Count
and Erythrocyte Sedimentation rate.

Biochemical investigation : Fasting Blood Sugar

7.4

Urine : Sugar, Albumin, Microscopic

X - Ray of Cervical Spine - AP and Lateral views(If necessary)

HAS

THE

ETHICAL

CLEARANCE

BEEN

OBTAINED

FROM

YOUR

INSTITUTION?

Yes, the clearance has been obtained through the ethical committee formulated in the
institution.
8.LIST OF REFERENCES:
1) Sushruta, sushruta samhita, With Nibandha sangraha commentary of Dalhanacharya & the
Nyaya chandrika panchika of Gayadas Acharya on Nidana sthana edited J.T . Acharya, 8 th
edition, Chaukamba Orientalia, Varanasi,Pp-824 , Page no-268,422.
2) Charaka, charaka samhita, with the Ayurveda-Dipika Commentary of Chakrapani Datta on
sutra Sathana edited by J.T. Acharya. Chaukamba Sanskrit Sansthan,8 th edition, Varanasi, Pp738, Page no-112.
3) Davidsons Principles and practice of medicine, Edited by Nicki R. Coledge. Part-2 ,
chapter 26, Nuerological diseases, Pp- ,Page no-1221.
4) Charaka, Charaka Samhita, with the Ayurveda-Dipika Commentary of Chakrapani datta on
sutra Sthana edited by J.T. Acharya, 8th edition,Chaukamba Sanskrit sansthan, Varanasi, Pp738 , Page no- 82.
5) Vagbhat, Ashtanga Hridaya, with Sarvanga Sundara commentary of Arunadatt and
Ayurveda Rasayana commentary of Hemadri on Sutra Sthana, Chaukamba Orientalia,14 th
edition, Varanasi , Pp-616 , Page no - 287, 534 & 727.

6) Vagbhat, Astanga Hridaya, with Sarvanga Sundara commentary of Arunadatt

and

Ayurveda Rasayana commentary of Hemadri on Chikitsa Sthana, Chaukamba orientalia,14 th

editionVaranasi, Pp-616 , Page no-532.
7) Charaka, Charaka Samhita, with Charaka Chandrika of Agnivesha on Chikitsa Sthana
edited by Dr. B.Tripati,11th edition,Chaukamba Sanskrit Sansthan, Varanasi, Pp-1450,Page no951.
8)Vagbhata,Astanga Hridaya, with the commentaries Sarvangasundara of Arunadatta and
Ayurvedarasayana of Hemadri on Sutra Sthanaedited by Pt. B.H. Paradkar Vaidya, 4th edition,
Choukamba Krishnadas Acadamy,Varanasi,Pp-956,Page no-722.
9) Charaka, Charaka Samhita, with the Ayurveda;Dipika Commentary of Chakrapani datta on
Sutra sthana edited by J.T. Acharya, 8 th edition,Chaukamba Sanskrit Sansthana,Varanasi,Pp738, Page no-114.
10) Charaka, Charaka Samhita, with Charaka Chandrika of Agnivesha on Chikitsa Sthana
edited by Dr.B.Tripati, 11th edition, Chaukambha Sanskrit Sansthana, Varanasi,Pp- 1450,Page
no- 937.
11) Sahasrayogam, written by Dr. Ramnivas Sharma and Dr. Surendra Sharma,Choukamba
Sanskrit Prathistana,Delhi, Pp-318,Page no-75.

12)Vagbhata, Astanga hridaya, with the commentaries Sarvangasundara of Arunadatta and

Ayurvedarasayana of Hemadri on Sutra Sthanaedited by Pt. B.H. Paradkar Vaidya, 4th edition,
Choukamba Krishnadas Acadamy,Varanasi,Pp-956,Page no-289.