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COURSE SYLLABUS
COLLEGE OF ARTS AND SCIENCES
Course Code
Course Title
Credit Units
Course Description
Contact Hours/week
Prerequisite
Course Objectives
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CHEM 103L
BIOCHEMISTRY
5.0
Biochemistry is a course that deals with the physical and chemical reactions occurring in the living cell at the molecular level. It encompasses the study of
chemistry of carbohydrates lipids, proteins, nucleic acids, and enzymes and their metabolism when taken as food by man. Furthermore, the course
provides diverse opportunities for the students to understand the significant functions of macro molecules in the human body.
3 hours (Lecture) & 6 hours (Laboratory) every week
CHEM 101L - General Chemistry
At the end of the semester, the students must be able to:
Classify biochemical substances into bioinorganic and bioorganic.
Discuss the morphology of a cell and the biochemical substances that comprises it.
Describe the general structure of a cell membrane and its chemical composition.
Distinguish between passive transport and active transport and between simple diffusion and facilitated diffusion.
Determine the role and significance of carbohydrates, acids in the human body
Define monosaccharides, disaccharides, and polysaccharides, and recognize examples.
Describe the chemical structures and general properties of fatty acids, waxes, fats, sterols, and oils
Define essential and nonessential amino acids, and describe the general strategy of amino acid biosynthesis.
Describe and identify the components of nucleosides, nucleotides, DNA, and RNA.
List the types of RNA, their locations in the cell, and their functions.
Explain the genetic code, and describe the initiation, elongation, and termination steps of translation.
Describe the chemical nature of enzymes and their function in biochemical reactions.
Provide an overview of what happens as one or more substrates and an enzyme come together so that the catalyzed reaction can occur, and be
able to list the properties of enzymes that make their specificity possible.
Describe the two major classes of vitamins, the reasons vitamins are necessary in our diet, and the general results of excesses or deficiencies.
Identify essential minerals, explain why minerals are necessary in the diet, and explain the results of deficiencies.
Describe carbohydrate digestion, its location, the enzymes involved, and name the major products of this process.
Give an overview of the glycolysis pathway and its products and identify where the major monosaccharides enter the pathway.
Identify the hormones that influence glucose metabolism and describe the changes in metabolism during starvation and diabetes mellitus.
List the sequence of events in the digestion of dietary triacylglycerols and their transport into the bloodstream.
Name the major pathways for the synthesis and breakdown of triacylglycerols and fatty acids, and identify their connections to other metabolic
pathways.
Enumerate the sequence of events in the digestion of proteins, and describe the nature of the amino acid pool.
List the major reactants and products of the urea cycle.
Describe in general the origins, pathways, and actions of hormones.
Give examples of different chemical types of hormones describe the general origins, pathways, and actions of neurotransmitters.
Identify neurotransmitters and drugs active in these conditions.
Describe the major categories of body fluids, their general composition, and the exchange of solutes between them.
Explain the composition and functions of blood.
Identify and describe the roles of blood components that participate in inflammation, the immune response, and blood clotting.
Week 2
Week 3
Carbohydrates
Week 4
Lipids
Week 5
Preliminary Examination
Week 6
Amino Acids
Week 7
Proteins
Week 8-9
Week 10
Midterm Examination
Week 11
Week 12
Week 13
Lipid Metabolism
Week 14
Semifinal Examination
Week 15
Carbohydrate Metabolism
Week 16
Week 17
Body Fluids
Week 18
Final Examination
2.5.
Provide an overview
of the sources of energy and
how it is being used
Identify the cellular
location of energy generation
Differentiate
anabolism and catabolism
Describe in general
the electron transport chain,
oxidative phosphorylation,
and how the two processes
are coupled
Describe what
Course Content/Subject
Matter
PRELIMS
1.
Overview of
Biochemistry
a. Class Orientation
b. Nature of Biochemistry
c. Attributes of Life
d. Biological Substances
e. Laboratory Safety
f. The Compound
Microscope
LEARNING PLAN
Teaching and Learning
Textbooks/References
Activities (TLAs)
Assessment Task
(ATs)
DYCI Values
Content
Resource
Materials
Time
Table
1. Quiz/Seatwork
2. Laboratory Activity:
Science Laboratory
Safety Test
3. Laboratory Activity:
The Compound
Microscope
1. Patience
2. Hard work
3. Perseverance
PowerPoint
Presentation
Week 1
1. Illustration of concepts
2. Label the parts of an
Animal Cell and
determine its functions
3. Observe the chick cell
under a compound
microscope
1. Seatwork
2. Watch and interpret
animation of
different metabolic
pathways
3. Scientific Article :
Basal Metabolism
4. Scientific Article :
Plants and
Photosynthesis
5. Laboratory Activity:
The Animal Cell
1. Patience
2. Dedication
3. Perseverance
Handout
Science
Laboratory
Lab. Sheet
Compound
Microscope
2.
PowerPoint
Presentation
Worksheet
Science
Laboratory
Lab. Sheet
Chick Cell
Biological
Stain
Microscope
Week 2
Course Content/Subject
Matter
3.
4.
Carbohydrates
a. The D and L Families of
Sugar
b. Monosaccharides
c. Disaccharides
d. Important
Polysaccharides
e. Digestion of Dietary
Carbohydrates
Lipids
a. Structure and
Classification of Lipids
b. Fatty Acids
c. Phospholipids and
Glycolipids
d. Structure of the Cell
Membrane
e. Transport Across Cell
Membrane
LEARNING PLAN
Teaching and Learning
Textbooks/References
Activities (TLAs)
McMurry, J., Ballantine
D.S., Hoeger C. A., &
Peterson, V. E. (2013).
Fundamentals of
General, Organic, and
Biological Chemistry.
(pg. 657 )
McMurry, J & Castellion
M.E. (2007). Essentials
of General, Organic,
and Biological
Chemistry.4th Ed. (pg.
628)
Stroker, H.S. (2013).
Exploring General,
Organic and Biological
Chemistry. 2nd Ed. (pg.
592)
Stoker, H.S. (2011).
Biochemistry. (pg. 1011)
McMurry, J., Ballantine
D.S., Hoeger C. A., &
Peterson, V. E. (2013).
Fundamentals of
General, Organic, and
Biological Chemistry.
(pg. 657 )
Stroker, H.S. (2013).
Exploring General,
Organic and Biological
Chemistry. 2nd Ed. (pg.
Assessment Task
(ATs)
Resource
Materials
1. Group Work
2. Board Work
3. Expressing Ones
Opinion
4. Laboratory Activity
1. Quiz/Seatwork
2. Scientific Article:
Carbohydrates and
Fiber in the Diet
3. Laboratory Activity:
Testing the
Presence of Sugar
1.
2.
3.
4.
Accuracy
Patience
Cooperation
Perseverance
PowerPoint
Presentation
1. Group Work
2. Interpret Diagrams and
Processes
3. Laboratory Activity
1. Quiz/Seatwork
2. Scientific Article:
Lipids in the Diet
3. Scientific Article:
Butter and Its
Substitutes
4. Laboratory Activity:
Cellular Transport
1.
2.
3.
4.
Patience
Cooperation
Perseverance
Accuracy
PowerPoint
Presentation
Time
Table
Week 3
Science
Laboratory
Lab. Sheet
Laboratory
Apparatuses
Science
Laboratory
Lab. Sheet
Compound
Microscope
Rheo
discolor
Cucumis
Week 4
PRELIMINARY EXAM
Course Content/Subject
Matter
MIDTERMS
5. Amino Acids
a. Structures and
Functions
b. Molecular Handedness
and Amino Acids
c. Essential Amino Acids
654)
Stoker, H.S. (2011).
Biochemistry. (pg. 1011)
sativus Linn.
Week 5
LEARNING PLAN
Teaching and Learning
Textbooks/References
Activities (TLAs)
McMurry, J., Ballantine
D.S., Hoeger C. A., &
Peterson, V. E. (2013).
Fundamentals of
General, Organic, and
Biological Chemistry.
(pg. 552 )
Assessment Task
(ATs)
Resource
Materials
1. Use of Animation
2. Group Discussion and
Sharing
3. Express Ones Opinion
1. Quiz/Seatwork
2. Scientific Article:
The Importance of
Essential Amino
Acids and Effects of
Deficiencies
3. Group Work
1.
2.
3.
4.
5.
Hard Work
Keenness
Patience
Cooperation
Perseverance
PowerPoint
Presentation
1. Quiz/Seatwork
2. Scientific Article:
Proteins in the Diet
3. Scientific Article:
Collagen A Tale of
Two Diseases
4. Scientific Article:
Prions: Proteins
That Causes
1. Patience
2. Accuracy
3. Perseverance
PowerPoint
Presentation
Time
Table
Week 6
Science
Laboratory,
Apparatuses,
and
Reagents
6.
Proteins
a. Structures and
Functions
b. Primary Protein
Structure
c. Secondary, Tertiary, and
Quaternary Protein
Structure
d. Chemical Properties of
Science
Laboratory,
Apparatuses,
and
Reagents
Week 7
give examples
Proteins
Course Content/Subject
Matter
MIDTERM EXAM
SEMI-FINALS
8. Chemical Messengers:
Hormones,
Neurotransmitters, and
Drugs
a. Messenger Molecules
b. Hormones and the
Endocrine System
c. Neurotransmitters
d. Histamine and
Antihistamine
Diseases
5. Laboratory Activity:
Test for the
Presence of Protein
LEARNING PLAN
Teaching and Learning
Textbooks/References
Activities (TLAs)
McMurry, J., Ballantine
D.S., Hoeger C. A., &
Peterson, V. E. (2013).
Fundamentals of
General, Organic, and
Biological Chemistry.
(pg. 774-793 )
Stoker, H.S. (2011).
Biochemistry. (pg. 239282)
McMurry, J & Castellion
M.E. (2007). Essentials
of General, Organic,
and Biological
Chemistry.4th Ed. (pg.
739)
Stroker, H.S. (2013).
Exploring General,
Organic and Biological
Chemistry. 2nd Ed. (pg.
798)
Assessment Task
(ATs)
1. Quiz/Seatwork
2. Scientific Article :
Proteins in the Diet
3. Scientific Article: Its
a Ribozyme!
4. Scientific Article :
Prions: Viruses and
AIDS
5. Laboratory Activity:
Extracting DNA
Patience
Accuracy
Perseverance
Cooperation
Resource
Materials
PowerPoint
Presentation
Time
Table
Week
89
Science
Laboratory,
Apparatuses,
and
Reagents
Week 10
1. Name the glands of
the Endocrine
system and the
respective
hormones they
produce.
2. Scientific Article:
Homeostasis
3. Scientific Article:
Plant Hormones
1. Appreciate the
importance of
hormones and
neurotransmitters
2. Patience
3. Cooperation
4. Perseverance
PowerPoint
Presentation
Science
Articles
Week 11
synthesis, combinatorial
chemistry, and computeraided design in the
development of new drugs.
4. Laboratory Activity:
Plant Tissue Culture
5. Seatwork
6. Pop Quiz
Course Content/Subject
Matter
LEARNING PLAN
Teaching and Learning
Textbooks/References
Activities (TLAs)
McMurry, J., Ballantine
D.S., Hoeger C. A., &
Peterson, V. E. (2013).
Fundamentals of
General, Organic, and
Biological Chemistry.
(pg. 568-610 )
McMurry, J & Castellion
M.E. (2007). Essentials
of General, Organic,
and Biological
Chemistry.4th Ed. (pg.
540 - 561)
Smith, J.G. (2010).
General, Organic, and
Biological Chemistry.
(597)
Stroker, H.S. (2013).
Exploring General,
Organic and Biological
Chemistry. 2nd Ed. (pg.
754-787)
Stoker, H.S. (2011).
Biochemistry. (pg. 192227)
Nucum, Z.T. (2010).
Simplified Biochemistry.
(pg. 89)
1. Group Dynamics
2. Pair and Share
3. Analysis of Science
Articles
4. Laboratory Activity
Assessment Task
(ATs)
1. Quiz/Seatwork
2. Science Article:
Extremozymes
Enzymes from the
Edge
3. Science Article:
Enzymes in Medical
Diagnosis
4. Science Article:
Enzyme Inhibitors
as Drugs
5. Science Article:
Vitamins, Minerals,
and Food Labels
6. Laboratory Activity:
Testing the
Specificity of
Digestive Enzymes
Accuracy
Patience
Cooperation
Perseverance
Resource
Materials
PowerPoint
Presentation
Science
Laboratory,
Apparatuses,
and
Reagents
Time
Table
Week 12
Course Content/Subject
Matter
SEMI-FINAL EXAM
11.1. Describe carbohydrate
digestion, its location, the
enzymes involved, and
name the major products of
this process.
11.2. Identify the pathways by
which glucose is
synthesized and broken
down.
11.3. Give an overview of
glycolysis pathway and its
FINALS
11. Carbohydrate Metabolism
a. Digestion of
Carbohydrates
b. Glucose Metabolism
c. Glycolysis
d. Regulation of Glucose
Metabolism and Energy
Production
e. Metabolism in Fasting
and Starvation
f. Metabolism in Diabetes
LEARNING PLAN
Teaching and Learning
Textbooks/References
Activities (TLAs)
McMurry, J., Ballantine
D.S., Hoeger C. A., &
Peterson, V. E. (2013).
Fundamentals of
General, Organic, and
Biological Chemistry.
(pg. 752-763 )
Stroker, H.S. (2013).
Exploring General,
Organic and Biological
Chemistry. 2nd Ed. (pg.
920-946)
Stoker, H.S. (2011).
Biochemistry. (pg. 376409)
Nucum, Z.T. (2010).
Simplified Biochemistry.
(pg. 172)
McMurry, J., Ballantine
D.S., Hoeger C. A., &
Peterson, V. E. (2013).
Fundamentals of
General, Organic, and
Biological Chemistry.
(pg. 692-713)
Stroker, H.S. (2013).
Exploring General,
Organic and Biological
Chemistry. 2nd Ed. (pg.
1. Group Dynamics
2. Pair and Share
3. Analysis of Science
Articles
Assessment Task
(ATs)
1. Quiz/Seatwork
2. Science Article:
Lipids and
Atherosclerosis
3. Science Article: Fat
Storage: A good
thing or Not?
4. Science Article: The
Liver, Clearinghouse
for Metabolism
Hard Work
Keenness
Patience
Cooperation
Perseverance
Resource
Materials
PowerPoint
Presentation
Time
Table
Week 13
Science
Articles
Week 14
1.
2.
3.
4.
Group Dynamics
Sharing of Opinions
Pair and Share
Simulation
1. Review Questions/
Problems
2. Science Article:
Tooth Decay
3. Science Article:
Diagnosis and
Monitoring of
Diabetes
4. Laboratory Activity:
Modelling Glucose
Regulation
1.
2.
3.
4.
Accuracy
Patience
Cooperation
Perseverance
PowerPoint
Presentation
Worksheets
and Activity
Sheets
Science
Article
Week 15
products.
11.4. Identify the hormones that
influence glucose
metabolism during
starvation and diabetes
mellitus.
Mellitus
g. Glycogenesis and
Glycogenolysis
h. Gluconeogenesis
Course Content/Subject
Matter
886-914)
Stoker, H.S. (2011).
Biochemistry. (pg. 327365)
Nucum, Z.T. (2010).
Simplified Biochemistry.
(pg. 127)
LEARNING PLAN
Teaching and Learning
Textbooks/References
Activities (TLAs)
McMurry, J., Ballantine
D.S., Hoeger C. A., &
Peterson, V. E. (2013).
Fundamentals of
General, Organic, and
Biological Chemistry.
(pg. 824-835 )
Stroker, H.S. (2013).
Exploring General,
Organic and Biological
Chemistry. 2nd Ed. (pg.
958-977)
Stoker, H.S. (2011).
Biochemistry. (pg. 419444)
Nucum, Z.T. (2010).
Simplified Biochemistry.
(pg. 223)
1. Group Dynamics
2. Pair and Share
3. Analysis of Animation
and Diagram
4. Laboratory Activity
1. Group Work
2. Pair and Share
3. Analysis of Animations
and Diagrams
4. Simulation
5. Laboratory Activity
Assessment Task
(ATs)
1. Quiz/Seatwork
2. Science Article:
Gout: When
Biochemistry Goes
Awry
3. Laboratory Activity:
Protein Digestion
Keenness
Accuracy
Patience
Cooperation
Perseverance
Resource
Materials
PowerPoint
Presentation
Time
Table
Week 16
Science
Laboratory,
Apparatuses,
and
Reagents
Science
Article
1. Quiz/Seatwork
2. Science Article: The
Blood-Brain Barrier
3. Science Article:
Automated Clinical
Laboratory Analysis
4. Laboratory Activity:
Predicting the
Success of Blood
Transfusions
5. Laboratory Activity:
Simulated Urinalysis
1. Accuracy
2. Patience
3. Cooperation
4. Perseverance
PowerPoint
Presentation
Science
Laboratory,
Apparatuses,
and
Reagents
Science
Article
Week 17
clotting.
13.4. Explain the relationship of
O2 and CO2 transport and
acid-base balance.
13.5. Describe the transfer of
water and solutes during
urine formation.
Formation
h. Urine Composition and
Function
FINAL EXAM
Week 18
Course Requirements
Grading System
Class Standing
40%
Written Examination
40%
Major Examination
Character
Project
10%
10%
Classroom Policies
Prepared by:
Approved by:
RYAN R. BAUTISTA
Faculty
CHARO G. GALANG
Librarian