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IThasgenerallybeenassumedthattheblackpigments(melanins)whichoccur normally or pathologically in animal tisues, hair, skin, feathers, etc. are chemically very inert substances, and in most cases their isolation has been carriedoutbydissolvingthetissueinboilingalkaliesorstrongacids. Thus Abel and Davis [1896] prepared melanins from both the skin and hair of a negrobyheatingthematerialat1000eitherwith5-6% potassiumhydroxide or witb concentrated hydrochloric acid until althe keratin had dissolved. Otherinvestigatorshaveusedevenmoredrasticmethodssuchasboilingwith moreconcentratedalkaliesorevenfuminghydrochloricacid.
IThasgenerallybeenassumedthattheblackpigments(melanins)whichoccur normally or pathologically in animal tisues, hair, skin, feathers, etc. are chemically very inert substances, and in most ca…