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NH2

Heavy chain

Constant region

S
S

S
S

S
NH2

S
S

NH2

Light chain

NH2
S

CHO

HOOC

Variable
region
CHO

COOH

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Antibody

Antigen

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d
a

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150

120
Secondary
response

Primary response
90

60

30

Primary
immunization

30

60

90
Days

120

150

180

Booster dose
of antigen
(secondary immunization)

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Hapten

T Cell
receptor

T
Cell

B
Cell
Antigen
Macrophage

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Induction by
antigen
Ag
B Cell

Nucleus
Cytplasm
1st day

Ribosomes
2nd day

Endoplasmic
reticulum
3rd day

Antibody

4th day
Plasma cell
Nucleus
Antibody
Antibody
molecules
5th day

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