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dolescence is a critical period for the development of psychological difficulties. Peak years for initial episodes of Major Depressive Disorder (MDD) are between 14 and 24 years of age (Kessler,
Avenevoli, & Merikangas, 2001); similarly, anxiety-spectrum disorders often emerge during adolescence (Kessler et al., 2005). A
substantial body of evidence supports the notion that recurrent
episodes of affective illness result in episode sensitization; that is,
greater incidences of depressive or bipolar episodes are related
to higher likelihood of additional future episodes (Kessing, Hansen, Andersen, & Angst, 2004; Post, 2007). Furthermore, children and adolescents with a psychiatric illness are at increased
risk for developing a comorbid disorder (Costello, Mustillo, Erkanli, Keeler, & Angold, 2003). Taken together, these findings
augur for the development of interventions aimed at mitigating
the impact of psychiatric illness in youth. Given the known genetic contributions of both affective and anxiety disorders (Martin,
Ressler, Binder, & Nemeroff, 2009; Sullivan, Neale, & Kendler,
2000) as well as the impact of trauma on mood (McEwen, 2008),
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Kessing, L. V., Hansen, M. G., Andersen, P. K., & Angst, J. (2004). The
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Sullivan, P. F., Neale, M. C., & Kendler, K. S. (2000). Genetic epidemiology of major depression: Review and meta-analysis. American
Journal of Psychiatry, 157, 1552-1562.
Lorie A. Ritschel, Ph.D.
Atlanta, GA
E-mail: Lorie.ritschel@emory.edu
Reproduced with permission of the copyright owner. Further reproduction prohibited without permission.