ProvidingSolutionstoChallengingProblems

ThroughSimilarityBasedMachineLearning

HealthcareandLifeScienceinstitutionsaredatadrivenbynatureandtheneedto
focus their efforts on turning information into positive outcomes is crucial. The
amount of information needed to accurately recommend a prescription, monitor
diabetes, track the readmission ofa patient,determine patient outcomes,manage
medicationandsupplyormanagetherevenuecycleofaninstitutionistoogreatto
beprocessedmanually.Theavailabilityofpredictivedataanalyticsmeansthatvast
quantitiesofinformation neededcanbe processedwithoutturningtospreadsheets
and human inputting of numbers, which greatly reduces risks and empowers
institutions to make better analysis, recommendations and predictions than ever
before. However, with the proliferation of medical devices, sensors and the
availability of data from EMRs, the deluge of unstructured data is very prevalent,
causing traditional analyticmethodstostruggleinprocessing and extracting value
fromthedata.

While existing Machine Learning algorithms can predict the future with great
accuracy, neither do they tell you what will cause an event nor why. In a Sector
(likeHealthcareand Life Sciences) whereeventheslightestmarginoferrorcanbe
perilous, whatweneedisatoolthatcannotonlyprovidepredictionsbutalsojustify
thepredictionsandprovidingthereasoningbehindtheprediction(theWHY).


Tools that adapt and evolve with the data and possess the dexterity to retrieve
quantifiable information and predictions that are transparent, justifiable and
understandablearerequired.

At simMachines, we are able to address this crucial need, by providing a cutting

edge technology that delivers answers to complex unsolvable questions in an
easily comprehensible andintuitivemanner.Ourawardwinning MachineLearning
(ML) technology enables a user to discover and predict answers to previously
unsolvable Healthcare problems with unparalleled performance. By providing
discovery, predictions, classifications and clusterings with thecomplete reasoning
behind the analysis (the WHY), our analytics are a grey box in contrast to the
industrynormofablackbox.

Traditional analytic techniques involve(bothstructuredandunstructured),provide

the freedom to analyze any data type in any form andalsoveslicing and dicing
thedataintosmallmorselsforalgorithmstoingest,thuslosingextremelyvaluable
information. Moreover, Healthcare data is typically stored in silos (when data
cannot be linked by a standard key) with very limited options to bridge the
information present across multiple platforms. By directly using the raw
unstructureddataandhavingtheabilitytoperformrecordlinkagesacrossmultiple
data silos, we are able to draw connections and establishrelationshipsbetween
datainanunprecedentedmanner.

Our similaritybased ML analytics includes, but is not limitedto,thespreadsheet

vector oriented (Euclidean) analysis of other methods. The development of our
fast similarity (dense nearest neighbour) engine enables the analysis of data
shapes beyond vectors (words and numbers) including biologic, chemical,
genomic data,3Dshapesandimages,complex,compoundtimeseriesdata,and
other formsofdatalayouts.TheseBeyondEuclideananalyticcapabilitiesenable
thediscoveryofnewinformationfromvirtuallyanydatashape.

Variousapplicationexamplesinclude, butarenotlimitedto:
PrecisionMedicine,
Managing and predicting sugar level spikes to analyze diabetes, Patient
Outcomes&ReadmissionMonitoring,MedicationManagement,Financeand
Revenue Cycle Management, Healthcare Fraud and Abuse Detection,
BiotechAnalysisandDrugDiscovery.

HealthcareandLifeScienceApplications
ThesimMachinestechnologyisideallysuitedtomeettherigorousrequirementsin
thehealthandlifesciencemarkets.Clinicalapplicationsinclude:

IdentifyingPatientsatRiskToImprovePatientManagementatLowerCost
PredictPatientAdherenceIssues
PrecisionMedicine
MedicationandSupplyManagement
ComparativeEffectivenessDrugandDevices
PostSurgeryTraumaandInfectionPrevention

Providerandpayorandintegratedprovider/payorapplicationsinclude:

IdentificationHealthcareFraud,AbuseWaste
PatientOutcomes
Customer/PatientEngagement
PopulationHealthManagement
ProviderNetworkManagementandComparativeEffectiveness

Lifescienceapplicationsinclude:

DrugTargetandDiscovery
IndicationDiscovery
ClinicalTrialPatientSelectionandDataAnalysis
AdverseDrugEventAnalysis