Beruflich Dokumente
Kultur Dokumente
Daniel G. Ye
Duke University
Christina S. Meade
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Delay discounting has been utilized extensively as a paradigm for impulsivity in substance users, because increased
delay discounting theoretically reflects a fundamental decision
making process present in substance using populations (Reynolds, 2006). While decision making is a complex process, part
of the phenomenology of substance dependence is that
substance-dependent persons often make choices that contradict
their stated goals. For example, a person may commit to quitting smoking one day, only to buy a pack of cigarettes the
following day. Delay discounting may be a key factor in how
that decision is reached. For those with high rates of delay
discounting, more distal rewards, like achieving 30 days of
sobriety or having funds to pay bills at the end of the month, are
underweighted compared with immediate rewards, such as substance use.
Delay discounting has been shown to correlate with other
measures of impulsivity, including trait impulsivity and sensation seeking (Caswell, Bond, Duka, & Morgan, 2015; Koff &
Lucas, 2011). However, other research has shown weak or
inconsistent associations (Mitchell, 1999; Vuchinich & Simpson, 1998). Research has demonstrated that higher delay discounting rates are associated with addictive behaviors across
many different substances, including nicotine, cocaine, opiates,
and alcohol compared with nondrug using controls (MacKillop
et al., 2011). Cocaine users in particular have demonstrated
greater delay discounting compared with nondrug users
(Garcia-Rodriguez, Secades-Villa, Weidberg, & Yoon, 2013;
Heil, Johnson, Higgins, & Bickel, 2006; Kirby & Petry, 2004).
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Method
Participants and Procedures
MCQ data was collected as part of a larger study examining the
neurocognitive effects of HIV and cocaine use (Meade, Towe,
Skalski, & Robertson, 2015). The community-based sample included 101 adult cocaine users who met the following inclusion
criteria: (a) 4 days of cocaine use in the past month or a positive
urine drug screen for cocaine, (b) 1 year of regular cocaine use,
and (c) lifetime cocaine dependence. Alcohol, marijuana, and
nicotine use were permitted, and current alcohol and marijuana
dependence were permitted if cocaine dependence was the principal diagnosis. For other drugs, individuals were excluded for
lifetime abuse or dependence, history of regular use, any use in the
past year, and/or a positive drug screen. Additional exclusion
criteria were: English nonfluency or illiteracy; ninth grade
education; serious neurological disorders (e.g., seizure disorder,
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Measures
Original Monetary Choice Questionnaire (MCQ-27).
Participants are presented with choices between smaller, immediate rewards and larger, delayed rewards (e.g., Would you prefer
$54 today or $80 in 30 days?; Kirby et al., 1999). The MCQ-27
includes a fixed set of 27 items with immediate rewards ranging
from $11$78 and delayed rewards ranging from $25$85 with a
delay of 7186 days. Delayed rewards are grouped into three
categories based on size, with nine items per category: small
($25$35), medium ($50 $60), and large ($75$85).
As described by Kirby et al. (1999), participants hyperbolic
discount parameter (k value) is determined by fitting data to the
following discount function equation: Vimmediate Vdelayed/(1
kD), in which V is the reward value in dollars and D is delay in
days (Mazur, 1984). Values of k range from 0.00016 to 0.25 for the
MCQ-27, with higher values indicating a greater preference for
smaller, immediate rewards over larger, delayed rewards. Each
possible k value increases by an order of approximately 2.5,
resulting in a logarithmic scale. K values are estimated by taking
the geometric midpoint between the discount rates associated with
each item and then examining the participants pattern of responses across trials to determine which k value is most consistent
with the response pattern. By examining the pattern of responses in
this way, one can infer a participants point of indifference between delayed and immediate rewards. To determine the most
consistent value, the proportion of a participants choices that are
consistent with each k value is calculated. The k value that yields
the highest proportion is the value assigned to the participant. If
two or more values have the same proportion, the participants
assigned k value is the geometric mean of those values. Because
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nearest whole dollar, and then the exact k for that dollar amount was
calculated with the formula. This resulted in k values for the MCQ-36
ranging from 0.00016 to 4.00. K values were also natural log transformed and ranked for the MCQ-36, with ranks ranging from 1 to 13.
Table 1 shows the items included in the MCQ-36 and their calculated
k values.
The MCQ-36 was computerized using ePrime (Psychology
Software Tools, Inc., http://www.pstnet.com). Choices were presented in random order, and participants indicated their response
using a computer mouse. Participants completed the full MCQ-36,
and then scores were generated for the original MCQ-27 and the
extended MCQ-36. Participants were told that all rewards were
hypothetical, and participants did not receive any money based on
their performance on the task.
Barratt Impulsiveness Scaleversion 11 (BIS-11). At the
neurocognitive assessment, participants completed the BIS-11
(Patton, Stanford, & Barratt, 1995), which is one of the oldest and
most widely used self-report measures of trait impulsivity (Stanford et al., 2009). The BIS-11 includes 30 items that describe
common impulsive or nonimpulsive behaviors and preferences.
Table 1
Items in the Extended Monetary Choice Questionnaire (MCQ-36)
Reward size
Amount today
Amount later
Delay in days
Calculated k valuea
Small
Small
Small
Small
Small
Small
Small
Small
Small
Smallb
Smallb
Smallb
Medium
Medium
Medium
Medium
Medium
Medium
Medium
Medium
Medium
Mediumb
Mediumb
Mediumb
Large
Large
Large
Large
Large
Large
Large
Large
Large
Largeb
Largeb
Largeb
34
28
22
25
19
24
14
15
11
6
5
7
54
47
54
49
40
34
27
25
20
12
13
12
78
80
67
69
55
54
41
33
31
17
13
17
35
30
25
30
25
35
25
35
30
25
30
35
55
50
60
60
55
50
50
60
55
50
55
60
80
85
75
85
75
80
75
80
85
80
75
85
186
179
136
80
53
29
19
13
7
5
3
1
117
160
111
89
62
30
21
14
7
5
2
1
162
157
119
91
61
30
20
14
7
6
3
1
0.00016
0.00040
0.00100
0.00250
0.00596
0.01580
0.04135
0.10256
0.24675
0.63333
1.66667
4.00000
0.00016
0.00040
0.00100
0.00252
0.00605
0.01569
0.04056
0.10000
0.25000
0.63333
1.61538
4.00000
0.00016
0.00040
0.00100
0.00255
0.00596
0.01605
0.04146
0.10173
0.24885
0.61765
1.58974
4.00000
Exact values calculated using the standard discount function equation, Vimmediate Vdelayed/(1 kD), in which
k represents the k value, V is the reward value in dollars and D is delay in days. b Item added to the MCQ-36
that was not included in the MCQ-27.
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1051
1052
Results
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This article is intended solely for the personal use of the individual user and is not to be disseminated broadly.
Participant Characteristics
The majority of participants were male (66%) and African
American (92%). Participants were 46.29 years old on average
(SD 8.46) and 49% of the sample was HIV-positive. Approximately 24% of the sample identified as gay, lesbian, or bisexual. Participants reported 12.24 years of education on average
(SD 2.40) and 84% reported being unemployed. Participants
had used cocaine on average 10.50 of the past 30 days (SD
7.64) and reported a mean of 17.80 years of regular cocaine use
(SD 7.48). The vast majority (88%) reported smoking as their
usual route of cocaine administration, and 85% of the sample
tested positive for cocaine in a urine drug screen completed on
the day the MCQ was administered.
Discussion
In this sample of active cocaine users, the modified MCQ-36
appeared to be successful in reducing a ceiling effect on k
scores compared with the MCQ-27. There was a clear ceiling
effect using the original MCQ-27 items, with over a quarter of
participants producing k values that exceeded the maximum
possible k value. This ceiling effect was reduced substantially
with the MCQ-36 to only four participants receiving the maximum possible k value. Based on these results, use of the
extended MCQ-36 may be warranted in populations with high
rates of impulsivity, such as out-of-treatment cocaine users, in
order to get a more accurate estimate of discounting parameters.
Table 2
Average K Values, ln K Values, and Ranks for the Original Monetary Choice Questionnaire (MCQ-27) and Extended Monetary
Choice Questionnaire (MCQ-36)
K value geo. mean (95% CI)a
ln k value M (SD)
Reward size
MCQ-27
MCQ-36
MCQ-27
MCQ-36
MCQ-27
MCQ-36
Small N 99
Medium N 98
Large N 97
Overall mean N 99
2.76 (1.34)
3.00 (1.35)
3.20 (1.38)
2.98 (1.20)
2.57 (1.62)
2.84 (1.61)
2.97 (1.80)
2.78 (1.51)
8.08 (1.58)
7.82 (1.58)
7.59 (1.63)
7.84 (1.43)
8.21 (1.81)
7.93 (1.80)
7.78 (2.02)
7.99 (1.69)
geo. mean geometric mean of raw k values, 95% CI 95% confidence intervals for each geometric mean.
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Small
Large
30
30
25
25
20
20
15
15
10
10
1 2
3 4 5 6 7 8 9 10 11 12 13
Ranked k values
1 2
Medium
30
30
25
20
20
15
15
10
10
5
0
3 4 5 6 7 8 9 10 11 12 13
Ranked k values
Overall Mean
35
25
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1 2
3 4 5 6 7 8 9 10 11 12 13
Ranked k values
1 2
3 4 5 6 7 8 9 10 11 12 13
Ranked k values
Figure 1. Histograms of ranked k-values across reward categories and by overall mean for the MCQ-36.
Shaded bars represent ranks from the original MCQ-27 items. Additional ranks from the extended k value scale
included in the MCQ-36 are unshaded. MCQ-27 Original Monetary Choice Questionnaire; MCQ-36
Extended Monetary Choice Questionnaire.
There were some notable differences between extreme responders and nonextreme responders on the SSS, though these
were not statistically significant after correcting for multiple
comparisons using the Bonferroni adjustment. Overall, extreme
responders had higher levels of sensation seeking compared
with nonextreme responders, and showed particularly high levels of sensation seeking in disinhibition and experience seeking.
Disinhibition reflects both social and sexual disinhibition that is
expressed in substance-use behaviors and variety in sexual
partners (Zuckerman et al., 1978). Experience seeking represents the pursuit of new sensations and experiences through the
mind and senses, and activities such as travel and a nonconforming lifestyle (Zuckerman et al., 1978).
There were few differences between extreme responders and
nonextreme responders on cocaine use, trait impulsivity, and
many other participant characteristics. The lack of differences
on cocaine use variables is very likely the result of strict
eligibility criteria for the sample related to frequency and
severity of cocaine use. Use of these strict criteria resulted in a
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Table 3
Comparison of Extreme Responders to Nonextreme Responders Using ANCOVA
Adjusted means
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Measure
Barratt Impulsiveness Scale
BIS-11 total score
Self-control
Motor impulsiveness
Attention
Cognitive instability
Cognitive complexity
Perseverance
Sensation Seeking Scale
SSS-V total score
Thrill and adventure seeking
Experience seeking
Disinhibition
Boredom susceptibility
Estimated premorbid verbal IQ
HRBS sex composite
BSI total score
Nonextreme responders
(N 73)
Extreme responders
(N 26)
65.18
14.69
14.51
9.93
4.66
13.16
8.23
65.52
15.60
13.71
10.28
5.04
13.12
7.78
F(1,
F(1,
F(1,
F(1,
F(1,
F(1,
F(1,
91)
91)
91)
91)
91)
91)
91)
.02
1.40
1.40
.29
1.04
.01
.87
14.22
3.23
4.62
4.14
2.23
86.83
3.37
0.49
17.04
3.52
5.56
5.48
2.47
82.71
4.34
0.53
F(1,
F(1,
F(1,
F(1,
F(1,
F(1,
F(1,
F(1,
91)
91)
91)
91)
91)
90)
91)
91)
5.14
.24
4.21
8.27
.37
2.04
1.19
.11
F value
Note. The covariates included were age, race, gender, years of education, sexual orientation, and occupational
status. Means presented represent the adjusted means after controlling for all covariates in the ANCOVA. BIS-11
point scales: total, 30 120; self-control, 6 24; motor impulsiveness, 728; attention, 520; cognitive instability,
312; cognitive complexity, 520; perseverance, 4 16. SSS-V point scales: total, 0 40; all subscales, 0 10.
ANCOVA analysis of covariance; SSS-V Sensation Seeking Scale - version V; HRBS HIV Risk
Behavior Scale; BSI Brief Symptom Inventory.
p .05. p .01.
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