0 Bewertungen0% fanden dieses Dokument nützlich (0 Abstimmungen)
70 Ansichten10 Seiten
The document discusses properties of different azole antifungal drugs. It presents multiple choice questions to test knowledge about these drugs. All questions are correct except one - statement D in the last set of questions, which says that both ketoconazole and itraconazole can cause cardiac toxicity when taken with astemizole, as only ketoconazole has this interaction.
The document discusses properties of different azole antifungal drugs. It presents multiple choice questions to test knowledge about these drugs. All questions are correct except one - statement D in the last set of questions, which says that both ketoconazole and itraconazole can cause cardiac toxicity when taken with astemizole, as only ketoconazole has this interaction.
The document discusses properties of different azole antifungal drugs. It presents multiple choice questions to test knowledge about these drugs. All questions are correct except one - statement D in the last set of questions, which says that both ketoconazole and itraconazole can cause cardiac toxicity when taken with astemizole, as only ketoconazole has this interaction.
All of the following questions concerning the azole antifungal drugs are correct EXCEPT:
A. Some of these agents inhibit cytochrome P450 enzymes and cause
the plasma concentration of certain co-administered drugs to build up. B. Ketoconazole (Nizoral) has a greater likelihood of disrupting the synthesis of sex steroids than either itraconazole (Sporanox) or fluconazole (Diflucan). C. Both ketoconazole and itraconazole require gastric acidity for adequate oral absorption. D. In the clinical setting, itraconazole and fluconazole are gradually being replaced by ketoconazole.
All of the following questions concerning the azole antifungal drugs are correct EXCEPT:
A. Some of these agents inhibit cytochrome P450 enzymes and cause
the plasma concentration of certain co-administered drugs to build up. B. Ketoconazole (Nizoral) has a greater likelihood of disrupting the synthesis of sex steroids than either itraconazole (Sporanox) or fluconazole (Diflucan). C. Both ketoconazole and itraconazole require gastric acidity for adequate oral absorption. D. In the clinical setting, itraconazole and fluconazole are gradually being replaced by ketoconazole.
6. All of the following questions concerning specific antifungal drugs
are correct EXCEPT:
A. Itraconazole (Sporanox) is the agent of choice for chronic
suppression of Histoplasmosis in immunocompromised patients. B. Itraconazole's excellent penetration into the CSF allows its use for treatment of fungal infections in the central nervous system. C. Itraconazole is approved for treatment of onychomycoses. D. Both ketoconazole and itraconazole can both cause cardiac toxicity when co-administered with astemizole, a long-acting antihistamine.
6. All of the following questions concerning specific antifungal drugs are
correct EXCEPT:
A. Itraconazole (Sporanox) is the agent of choice for chronic
suppression of Histoplasmosis in immunocompromised patients. B. Itraconazole's excellent penetration into the CSF allows its use for treatment of fungal infections in the central nervous system. C. Itraconazole is approved for treatment of onychomycoses. D. Both ketoconazole and itraconazole can both cause cardiac toxicity when co-administered with astemizole, a long-acting antihistamine.
Select the single best answer from the following statements
about antifungal azoles.
A. Itraconazole (Sporanox) is approved for single-dose
treatment of vaginal yeast infections. B. Ketoconazole (Nizoral) is least likely to disturb synthesis of testosterone. C. Ketoconazole does not require gastric acidity for adequate oral absorption. D. Fluconazole's pharmacokinetic properties are virtually equivalent after IV and oral administration.
Select the single best answer from the following statements
about antifungal azoles.
A. Itraconazole (Sporanox) is approved for single-dose
treatment of vaginal yeast infections. B. Ketoconazole (Nizoral) is least likely to disturb synthesis of testosterone. C. Ketoconazole does not require gastric acidity for adequate oral absorption. D. Fluconazole's pharmacokinetic properties are virtually equivalent after IV and oral administration.
All of the following questions concerning specific antifungal drugs
are correct EXCEPT:
A. Itraconazole (Sporanox) is the agent of choice for chronic
suppression of Histoplasmosis in immunocompromised patients. B. Itraconazole's excellent penetration into the CSF allows its use for treatment of fungal infections in the central nervous system. C. Itraconazole is approved for treatment of onychomycoses. D. Both ketoconazole and itraconazole can both cause cardiac toxicity when co-administered with astemizole, a long-acting antihistamine.
All of the following questions concerning specific antifungal drugs are
correct EXCEPT:
A. Itraconazole (Sporanox) is the agent of choice for chronic
suppression of Histoplasmosis in immunocompromised patients. B. Itraconazole's excellent penetration into the CSF allows its use for treatment of fungal infections in the central nervous system. C. Itraconazole is approved for treatment of onychomycoses. D. Both ketoconazole and itraconazole can both cause cardiac toxicity when co-administered with astemizole, a long-acting antihistamine.