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Study design
Retrospective.
Identification of quantitative parameters to distinguish between CAP and HCAP.
Patients admitted with a diagnosis of pneumonia.
Initially categorized as HCAP or CAP based on history and bacterial cultures.
Additional lab parameters compared:
Creactive protein (CRP);
Mean platelet volume (MPV);
Red blood cell distribution width (RDW);
Neutrophil/lymphocyte ratio (NLR).
126 patients.
Key results
2 lab parameters significantly distinguished HCAP from CAP:
Average NLR was 14.37 in HCAP and 9.39 in CAP (P<0.01);
Average RDW was 16% in HCAP and 14.098% in CAP (P<0.01).
http://www.univadis.co.uk/viewarticle/pneumonia-which-tests-di... 04-Jul-16
Limitations
Patients with HCAP may have additional infections affecting these parameters.
As infection severity increases, so does the NLR.
Prior use of medication may alter results.
Takeaway
Study shows 2 routine laboratory parameters that distinguish community-acquired from
healthcare-associated pneumonia, regardless of medical history or clinical signs and symptoms.
Study design
Retrospective.
Identification of quantitative parameters to distinguish between community-acquired
pneumonia (CAP) and healthcare-associated pneumonia (HCAP).
Patients admitted with a diagnosis of pneumonia.
Initially categorized as HCAP or CAP based on history and bacterial cultures.
Additional lab parameters compared:
Creactive protein (CRP);
Mean platelet volume (MPV );
Red blood cell distribution width (RDW);
Neutrophil/lymphocyte ratio (NLR).
126 patients.
http://www.univadis.co.uk/viewarticle/pneumonia-which-tests-di... 04-Jul-16
Limitations
Patients with HCAP may have additional infections affecting these parameters.
As infection severity increases, so does the NLR.
Prior use of medication may alter results.
References
http://www.univadis.co.uk/viewarticle/pneumonia-which-tests-di... 04-Jul-16