Beruflich Dokumente
Kultur Dokumente
MYELODYSPLASTIC
BENIGN HTN:
showing HYALINE ARTERIOLOSCLEROSIS.
AFB STAINING:showing bacilli inside macrophages
MYELOBLAST:granular cytoplasm and 3-5 prominent nucleoli
LYMPHOBLAST:Agranular cytoplasm with no nucleoli
SECONDARY T.B.--caseous necrotic areas with many CAVITATORY lesions.
ELECTRON MICROSCOPY:1) shows "DENSE CORE GRANULES "( you can appreciate round dark black structures which are
NEUROSECRETORY GRANULES )
2) seen in NEUROENDOCRINE TUMOURS
3) MARKERS are ------ chromogranin, neuron specific enolase, synaptophysin, leucine -7
Malignant hypertension showing --1)ONION SKIN APPEARENCE...
2) HYPERPLASTIC ARTERIOSCLEROSIS...
3) FIBRINOID NECROSIS
ZELLBALLEN PATTERN(nests of chief cells surrounded by vascular septae)
seen in PARAGANGLIOMA.
AUER RODS - single rod like cytoplasmic structure)----max. in AML-M3( ACUTE PROMYELOCYTIC LEUKEMIA)...
CONGENITAL NEMALINE ROD MYOPATHY( LIGHT MICROSCOPY) ROD LIKE CYTOPLASMIC INCLUSIONS ( floppy
infant )
DERMATITIS HERPETIFORMIS:a/w HLA DQ-2 AND HLA-DQ-8.
SUBEPIDERMAL BLISTERS( neutrophilic microabscess in dermal pappilae)
DIRECT IMMUNOFLUOROSCENCE showing SELECTIVE IgA depositon at DERMAL -PAPPILAE TIP---- DERMATITIS
HERPETIFORMIS
CONGENITAL NEMALINE ROD MYOPATHY( electron MICROSCOPY) showing Z- band ( made of actinin; and also
known as ZEBRA BODIES)
HAIRY CELL( HAIRY CELL LEUKEMIA :
PHASE -CONTRAST MICROSCOPY--CD 11,25,103+VE.....
MOST SPECIFIC MARKER---ANNEXIN A1
RANKES COMPLEX :Ghons focus alongwith FIBROSIS and CALCIFICATION known as RANKES COMPLEX.
LACUNAR REED STERNBERG CELLS:-(notice clear space around nucleus thats why lacunar!!!!! its artifact!!!!)
Seen in NODULAR SCLEROSIS HL
CD 15+/30+
NESTROF TEST (Naked Eye Single Tube Rbc Osmotic Fragility test):Thallessemia screening
interpretation of test ---1).lines seen --NORMAL.