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Introduction
Definition
o degenerative disease of synovial joints that causes progressive
loss of articular cartilage
Epidemiology
o incidence
hip OA (symptomatic)
88 per 100,000 per year
knee OA (symptomatic)
240 per 100,000 per year
Risk factors
o modifiable
articular trauma
occupation, repetitive knee bending
muscle weakness
large body mass
metabolic syndrome
central (abdominal) obesity, dyslipidemia (high
triglycerides and low-density lipoproteins), high
blood pressure, and elevated fasting glucose
levels.
o non-modifiable
gender
females >males
increased age
genetics
race
African American males are the least likely to
receive total joint replacement when compared to
whites and Hispanics
Pathophysiology
o pathoanatomy
articular cartilage
increased water content
alterations in proteoglycans
eventual decrease in amount of
proteoglycans
collagen abnormalities
organization and orientation are lost
binding of proteoglycans to hyaluronic acid
synovium and capsule
early phase of OA
mild inflammatory changes in synovium
middle phase of OA
moderate inflammatory changes of synovium
synthesis
examples
IL-1
IL-6
TNF-alpha
Genetics
o inheritance
non-mendilian
o genes potentially linked to OA
vitamin D receptor
estrogen receptor 1
inflammatory cytokines
IL-1
leads to catabolic effect
IL-4
matrilin-3
BMP-2, BMP-5
Presentation
History
o identify age, functional activity, pattern of arthritic involvement,
overall health and duration of symptoms
Symptoms
o recommended views
weight-bearing views of affected joint
o optional views
knee
sunrise view
PA view in 30 degrees of flexion
o findings
pattern of arthritic involvement
medial and/or lateral tibiofemoral, and/or
patellofemoral
characteristics
joint space narrowing
osteophytes
eburnation of bone
subchondral sclerosis
subchondral cysts
Studies
Histology
o loss of superficial chondrocytes
o replication and breakdown of the tidemark
o fissuring
o cartilage destruction with eburnation of subchondral bone
Treatment
Nonoperative
o non-steroidal anti-inflammatory drugs
indications
first line treatment for all patients with symptomatic
arthritis
technique
Non-steroidal anti-inflammatory drugs (first choice)
selection should be based on physician
preference, patient acceptability and cost
duration of treatment based on effectiveness,
side-effects and past medical history
outcomes
AAOS guidelines: strong evidence for
o rehabilitation, education and wellness activity
indications
first line treatment for all patients with symptomatic
arthritis
technique
self-management and education programs
combination of supervised exercises and home program
have shown the best results
these benefits lost after 6 months if exercises are
stopped
outcomes
AAOS guidelines strong evidence for
Operative
o high-tibial osteotomy
indications
younger patients with medial unicompartmental OA
technique
valgus producing proximal tibial oseotomy
outcomes
AAOS guidelines: limited evidence for
o unicompartmental arthroplasty (knee)
indications
isolated unicompartmental disease
outcomes
TKA have lower revision rates than UKA in the setting
of unicompartmental OA
o total knee arthroplasty
indications
symptomatic knee osteoarthritis
failed non-operative treatments
techniques
cruciate retaining vs. crucitate sacrificing implants show
no difference in outcomes
patellar resurfacing
no difference in pain or function with or without
patella resurfacing
lower reoperation rates with resurfacing
drains are not recommended
Introduction
Designs include
o unconstrained
posterior-cruciate retaining (CR)
posterior-cruciate substituting (PS)
o constrained
nonhinged
hinged
o fixed versus mobile bearing
History
19th century
o interposition of soft tissues for reconstruction of articular surfaces
1950s
o Walldius designs first hinged knee replacement
1958
o MacIntosh and McKeever introduce acrylic tibial plateau prosthesis
to correct deformity
1960s
o Gunston introduces first cemented surface arthroplasty of knee
joint
1970
o Guepar develops a new hinged prosthesis based on design by
Walldius that increases motion and decreases bone loss
~1973
o "total condylar prosthesis" is introduced which is first to resurface all
three compartments (PCL sacrificing)
Concepts in Prosthetic Design
Femoral rollback
o definition
o importance
o biomechanics
o design implications
both PCL retaining and PCL substituting designs allow for femoral
rollback
PCL retaining
PCL substituting
Constraint
o definition
the ability of a prosthesis to provide varus-valgus and flexionextension stability in the face of ligamentous laxity or bone loss
o importance
o design implications
cruciate-retaining
posterior-stabilized (cruciate-substituting)
rotating-hinge
Modularity
o definition
o options include
has an equivalent rate of aseptic loosening compared with allpolyethylene tibia component
o advantages
o disadvantages
Design
Indications
o arthritis with minimal bone loss, minimal soft tissue laxity, and an intact PCL
o varus deformity < 10 degrees
o valgus deformity < 15 degrees
Radiographs
o radiographs won't show box in the central portion of the femoral component
as PS knees have (see PS knee radiographs)
Advantages
o avoids tibial post-cam impingement/dislocation that may occur in PS knees
o more closely resembles normal knee kinematics (controversial)
o less distal femur needs to be cut than in a PS knee
o improved proprioception with preservation of native PCL
Disadvantages
o tight PCL may cause accelerated polyethylene wear
o loose or ruptured PCL may lead to flexion instability and subluxation
Design
o slightly more constrained prosthesis that requires sacrifice of PCL
o femoral component contains a cam that engages the tibial polyethylene post
during flexion
o polyethylene inserts are more congruent, or deeply "dished"
Indications
o previous patellectomy
o inflammatory arthritis
Radiographs
o lateral radiograph will show the outline of the cam, or box, in the femoral
component
Advantages
o easier to balance a knee with absent PCL
o arguably more range of motion
o easier surgical exposure
Disadvantages
o cam jump
mechanism
treatment
initial
final
mechanism
treatment
Design
varus/valgus stability
rotational stability
Indications
o LCL attenuation or deficiency
o MCL attenuation or deficiency
Radiographs
o
Advantages
o prosthesis allows stability in the face of soft tissue (ligamentous) or bony
deficiency
Disadvantages
o more femoral bone resection
o aseptic loosening
Design
o most constrained prosthesis with linked femoral and tibial components
(hinged)
o tibial bearing rotates around a yoke on the tibial platform (rotating hinge)
Indications
o global ligamentous deficiency
o hyperextension instability
Radiographs
o
Advantages
o prosthesis allows stability in the face of soft tissue (ligamentous) or bony
deficiency
Disadvantages
o aseptic loosening
Design
o minimally constrained prosthesis where the polyethylene can rotate on the
tibial baseplate
o PCL is removed at time of surgery
Indications
Advantages
o theoretically reduces polyethylene wear
Disadvantages
o bearing spin-out
mechanism
treatment
initial
closed reduction
final
TKA Approaches
Author: Mark Karadsheh
Topic updated on 02/11/15 10:51pm
Introduction
Incision planning
o if multiple incision, choose more lateral
Approaches
o "simple" primary knee arthroplasty approaches
medial parapatellar
midvastus
subvastus
minimally invasive
medial parapatellar
quadriceps snip
V-Y turndown
Overview
o most commonly completed through a straight midline incision
Advantages
o familiar for most orthopaedic surgeons
o excellent exposure even in challenging cases
Disadvantages
o possible failure of medial capsular repair
o development of lateral patellar subluxation
o access to lateral retinaculum less direct
o may jeopardize patellar circulation if lateral release is performed
Overview
o useful for addressing lateral contractures but difficult eversion of
patella makes exposure challenging
Advantages
Disadvantages
o technically demanding
Overview
o similar approach to medial parapatellar that spares VMO insertion
and may lead to quicker recovery
Advantages
o vastus medialis insertion on quad tendon is not disrupted
o potentially allows accelerated rehab due to avoiding disruption of
extensor mechanism
o patellar tracking may be improved compared to medial parapatellar
approach
Disadvantages
o less extensile
o exposure difficult in obese patients
o exposure difficult with flexion contractures
Relative contraindications
o ROM <80 degrees
o obese patient
o hypertrophic arthritis
o previous HTO
Subvastus Approach
Overview
o muscle belly of vastus medialis is lifted off intermuscular septum
Advantages
o patellar vascularity preserved
o extensor mechanism remains intact
o minimal need for lateral retinacular release
Disadvantages
o least extensile
o potential for denervation of VMO
Relative contraindications
o revision TKA
o large quadriceps
o previous HTO
o obese patient
o previous parapatellar arthrotomy
Overview
o often need special instruments for exposure and implant insertion
o technically demanding
Outcomes
o short term data suggests more rapid recovery
o long term data needed to compare outcomes to traditional exposures
Extensile Exposures
Quadriceps snip
o technique
o advantages
o disadvantages
V-Y turndown
o technique
o advantages
o disadvantages
extensor lag
o advantages
excellent exposure
o disadvantages
non-union
Definitions
o simultaneous
o sequential
one surgeon performing one TKA and then the contralateral TKA under one
anesthetic
o staged
Other
Introduction
Important consideration
o pre-op planning
o component insertion
o ligament balancing
o prosthetic design selection
Normal anatomy
o distal femur in 5-7 degrees of valgus
o proximal tibia is 2-3 degrees of varus
Technical goals
o restore mechanical alignment (mechanical alignment of 0)
o restore joint line ( allows proper function of preserved
Radiographs
o standing AP and lateral of knee
to evaluate for
joint space narrowing
collateral ligament insufficiency (look for lateral
gapping)
subluxation of femur on tibia
bone defects
o standing full-length radiographs (AP and Lateral)
are indicated to determine an accurate valgus cut angle when
the patient has
femoral or tibial deformity
very tall or short stature
o extension and flexion laterals
o sunrise view
Femoral Alignment
Anatomic axis femur (AAF)
Introduction
Definition
o both medial and lateral ligaments may be stretched or
contracted with time
Goal is to create symmetrical bone cuts, and then release the tight
medial ligaments and tighten the lax lateral ligaments to balance
flexion and extension gaps
Lateral tightening
o use a prosthesis that is sized to "fill up" the gap and make the
stretched lateral ligaments taut
Introduction
Goal is to obtain a gap that is equal in flexion and extension. This will
ensure that the tibial insert is stable throughout the arc of motion.
o balancing is complex due to two radii of curvatures
(patellofemoral articulation and tibiofemoral articulation)
o often requires soft tissue release and bony resection to obtain
balance
General Rules
o adjust femur if asymmetric
distal femur cut affects extension gap
posterior femur cut affects flexion gap
o adjust tibia if problem is symmetric (same in both flexion and
extension)
tibia cut affects both flexion and extension gap
o remember increasing/decreasing the size of the femoral
component only changes the AP diameter and does not affect
the height of the prosthesis.
Evaluation & Treatment
The following chart shows different conditions found with the trials in place and the
treatment strategy for each condition.
Tight in Flexion
(can not fully flex)
Tight in Extension,
Tight in Flexion
Tight in
Extension
(can not fully
extend)
Balanced in
Flexion
Tight in Extension,
Balanced in Flexion
Problem:
Problem:
Did not cut enough
Did not cut enough distal femur or did not
tibia
release enough
Solution:
posterior capsule
Cut more proximal
Solution:
tibia
1) Release posterior
capsule
2) Cut more distal
femur
Balanced in
Balanced
in Extension, Tight in
Flexion
Extension
Problem:
Did not cut enough
Loose in Flexion
(large drawer test)
Tight in Extension,
Loose in Flexion
Problem:
Distal femur too long.
Solution:
1) Resect more distal
femur or use thinner
distal femoral
augmentation wedge
(revision scenario)
2) Upsize femoral
component
Balanced in
Balanced in Extension,
extension, Balanced
Loose in Flexion
in Flexion (Perfect)
Problem:
Loose in Extension,
Tight in Flexion
Loose in Extension,
Loose in Extension,
Balanced in Flexion
Loose in Flexion
Problem:
Problem:
Loose in
Solution:
Cut too much distal Cut too much tibia.
Extension 1) Downsize femur
femur.
Solution:
(recurvatum) and use thicker tibial
Solution:
1) Use thicker tibia PE
insert until balanced.
1) Augment distal
2) Use thicker tibial
femur
metal insert
Introduction
Patella baja is characterized by lowering of the patella relative to its
normal position
o may be congenital or acquired (this topic)
Pathophysiology of acquired patella baja
o common causes include
proximal tibial osteotomy
patella baja is the most common complication seen
Presentation
Symptoms
o anterior impingement knee pain
o knee stiffness
Physical exam
o mechanical block to full flexion
Imaging
Radiographs
o recommended views
o findings
Treatment
Nonoperative
o activity modifications, physical therapy
indications
Operative
o total knee replacement
indications
Techniques
technique
technique is difficult due to complexity of a tibial
transfer in proximity to a cemented tibial
component
outcomes
unpredictable bone healing leads to variable, and
often poor, outcomes
patients may be left with extensor lag
patellectomy
indications
severe patella baja
techniques
alters the tension in the anterior knee mechanism
therefore must use a cruciate substituting
system
TKA Rehabilitation
Author: Mark Karadsheh
Topic updated on 10/11/14 11:57am
Introduction
o case manager
o nursing staff
o patient and patient's family
Care can be broken down into different phases including
o inpatient acute care (hospital)
o inpatient extended care (rehab/SNF)
o outpatient home care
Inpatient Acute Care (Hospital)
Pain management
o preoperative
NSAIDS and opioids given immediately before procedure
reduce postoperative pain
o intraoperative
regional anesthesia (spinal and/or epidural)
preferred over general anesthesia
peripheral nerve blocks
useful adjuvant to decrease postoperative pain
periarticular multimodal drug injection
decrease postoperative pain with minimal risks
o postoperative
multimodal oral drug therapy
gold standard
Range of motion
o requirements
swing phase of gait
65 degrees of flexion
activities of daily living
90 degrees of flexion
rise from a chair
105 degrees of flexion
o continuous passive motion (CPM) machine
may improve early knee flexion
has not been shown to have a long-term benefit
Discharge home criteria
o medically stable
o 80-90 degrees AROM knee flexion
o ambulate 75-100 feet
o ascend or descend stairs
Inpatient Extended Care (Rehab)
Outpatient Care
Physical therapy
o 2-3x per week for at least 2 weeks
Return to activities
o low-impact closed chain exercises preferred
eliptical
biking
golf
handicap will show rise after TKA (stays same with THA)
running is discouraged
Driving recommendations
o 4 weeks after a right total knee
o less than 4 weeks after a left total knee
Introduction
smaller incision
less post-operative pain leading to shorter hospital
stays
o compared to osteotomy
faster rehabilitation and quicker recovery
improved cosmesis
higher initial success rate
fewer short-term complications
lasts longer
easier to convert to a TKA
Indications
Indications
o controversial and vary widely
o as an alternative to total knee arthroplasty or osteotomy for unicompartmental
disease
o classicaly reserved for older (>60), lower-demand, and thin (<82 kg) patients
o new effort to expand indications to include younger patients and patients with
more moderate arthrosis
Contraindications
o inflammatory arthritis
o ACL deficiency
Procedural tips
o avoid overcorrections
fractures
o correct varus deformity to 1-5 degrees of valgus
Complications
Stress fractures
o always involve tibia
o associated with high activity and patient weight
o clinically there will be a pain free interval followed by spontaneous pain with
activity
o blood commonly found on joint aspiration
Outcomes
Fixed-bearing
o 1st decade results
Mobile-bearing
o excellent clinical results with 15-year survivorship reported at 93%
Long-term results
o lateral compartment arthroplasties have equivalent results to medial
o revision rates are worse than total knee revision rates
polyethylene wear
Knee Arthrodesis
Author: Ben Taylor
Topic updated on 05/25/14 7:34pm
Introduction
Indications
o technique
Nonunion
Infection
Low back pain
Ipsilateral hip degenerative changes
Contralateral knee degenerative changes
Fracture
o supracondylar femur or proximal tibial metaphysis fractures
these occur from increased stress in these regions after
arthrodesis