d

Officer

October 17, 2011

Re: Iain MacLeod

Global Health Fellowship in Medicine at BIDMC

Scottish Livingstone Hospital Botswana
Beth Israel Deaconess Medical Center Boston, MA

To: Immigration Officer

The
Israel
Deaconess
Global
Healthsupport
Fellowship
was launched in 2015 to enable
I amBeth
writing
this letter
to provide
the strongest
possible in
forMedicine
Dr. Iain MacLeod,
who has applied
for the leaders
permanent
Immigration
Petition.disparities
I am an Associate
clinicians
to become
inresidency
addressing
global health
by developing and strengthening skills
Professor in Medicine at Harvard Medical School and Associate Professor in
asImmunology
effective,and
humble
practitioners
innovators
resource-challenged
Infectious
Diseases at and
Harvard
School ofin
Public
Health. My primary settings. The fellowship centers
research
interests are in the in
prevention
mother-to-child
HIV transmission
(PMTCT)
on
core responsibilities
clinicalofstewardship,
medical
education
and quality improvement provided in
and the reduction of morbidity and mortality among infants born to HIV-infected women.
the
context
of
a
robust,
long-term
local
partnership.
Since 1999, I have studied infant outcomes and peripartum PMTCT strategies in

letter to provideBotswana.
the strongest
support
forofDr.
I am the
principalpossible
investigator
the Iain
Mma MacLeod,
Bana Study, which evaluated
virologic
efficacyImmigration
and HIV transmission
ratesIamong
730Associate
women receiving 3 different
for the permanent
residency
Petition.
am
an
The
fellowship
includes:
antiretroviral combinations during pregnancy, delivery, and breastfeeding. The results
edicine at Harvard
andwas
Professor
in to lessatthan
showed
that
each of School
the treatments
effective
and cut
HIV transmission
1
- Medical
6 consecutive
months
asAssociate
clinician-educators
in Botswana
Scottish
Livingston Hospital (SLH)
percent.
am also aSchool
co-investigator
for a pilot
implementation
study to provide male
Infectious Diseases
at IHarvard
of
Public
Health.
My
primary
o Ward/teaching
attending
overseeing
rotating US medical residents
infant circumcision
services in Botswana.
I workresponsibilities,
closely with the Botswana
PMTCT
are in the prevention
mother-to-child
HIV
transmission
(PMTCT)
Program,ofand
I am
a member and
of
theBotswana
PMTCT
Advisory
Panel
for the
Health
(>30/year)
medical
interns
andWorld
students
Infectious
Disease
residents,
and students who are
of morbidity andOrganization.
mortality among
infants
born
to HIV-infected
women.
oI mentor
Unique
tofellows,
gain HIV.
clinical
experience
in managing a truly wide range of medical
interested in research
projectsopportunity
related to international
ave studied infant outcomes conditions
and peripartum
PMTCT
strategies
in
including
infectious
and non-communicable
diseases in both inpatient and
Dr. MacLeod has collaborated with me on some important projects. We recently
the principal investigator
of
the
Mma
Bana
Study,
which
evaluated
outpatient
settings.
submitted a publication to the journal Antimicrobial Agents and Chemotherapy titled
y and HIV transmission
among
730
receiving
3 different
Abacavirrates
alters
transcription
offocus
inflammatory
cytokines
in virologically
suppressed,
o the
Fellows
willwomen
on
local
capacity
building through
provision of:
HIV-infected women. He was given a Young Investigator Award for his presentation of
mbinations duringthispregnancy,
delivery,
and breastfeeding.
The resultsand mentorship
Outstanding
clinical stewardship
work at the Conference on Retroviruses and Opportunistic Infections this year. Our
the first
report
of
differences
in cytokine
expression
cut Dedicated
medical
education
of the treatmentsdata
waswere
effective
and
HIV
transmission
to less
than 1 mediated at the
transcriptional level in HIV-infected individuals treated with an abacavir-containing

Collaborative
quality
/
process
improvement
projects, with expectation of
o a co-investigator
for
a
pilot
implementation
study
to
provide
male
regimen. Previous studies chose to assess circulating inflammatory
mediators based on
their reportedI associations
with
cardiovascular
diseases and PMTCT
systemic inflammation. Our
scholarly
workBotswana
on services in Botswana.
work closely
with the
approach allowed us to simultaneously profile the expression of a large number of
groups,
Local
systems
strengthening
in clinical service delivery
am a member ofcytokines
the PMTCT
Advisory
Panel
for results
the
World
in two treatment
and these
suggest a Health
heightened transcriptional
response
for
inflammatory
mediators
in
those
treated
with
the
drug. His work has

Medicine
consult
service
at
SLH
mentor Infectious Disease fellows, residents, and students who are
highlighted that there is a need to expand the scope of research on abacavir beyond the
HIV.
Administrative support to Country Program Director
arch projects related
to international
traditional
biomarkers of
systemic inflammation to understand cellular messaging and
ultimately,
the mechanism
of inflammation.
- 6 months
as hospitalist
in the

Boston area BIDMC Hospital Medicine group

o
Inpatient
ward
attending
opportunities
at a nationally renowned internal medicine
as collaborated with me on some important projects.
We recently
residency
program
ication to the journal Antimicrobial Agents and Chemotherapy titled
- Regular clinical
case in
conferences
throughout
the year
he transcription of inflammatory
cytokines
virologically
suppressed,
-
Online
course
work
towards
completion
of
a
certificate
in Tropical Medicine & Hygiene (UMinn)
men. He was given a Young Investigator Award for his presentation of
- Round-trip
airfare to Botswana;
provision
of in-country
work-related transport
Conference on Retroviruses
and Opportunistic
Infections
this year.
Our
-
Annual
salary
of
$75K
irst report of differences in cytokine expression mediated at the

vel in HIV-infected individuals treated with an abacavir-containing

We are seeking compassionate, energetic, humble candidates who are comfortable working in a
s studies chose to assess circulating inflammatory mediators based on
demanding resource-challenging environment in Africa. Candidates must be equally comfortable
ociations with cardiovascular diseases and systemic inflammation. Our
assuming responsibilities as an attending-level physician in a top US hospital medicine group. We desire
d us to simultaneously profile the expression of a large number of
motivated learners and team players enthusiastic about addressing global health disparities.
treatment groups, and these results suggest a heightened transcriptional
ammatory mediators
in information
those treated
with
drug.Botswana
His work
has and the Global Health Fellowship, please
For more
about
the the
BIDMC
Program
here is a need tovisit
expand
the
scope
of
research
on
abacavir
beyond
the
http://www.bidmc.org/Medical-Education/Departments/Medicine/Residency-in-Internalrkers of systemic
inflammation
to
understand
cellular
messaging
and
Medicine/GlobalHealth/Botswana.aspx
echanism of inflammation.
or contact Fellowship Director Dr. Jonathan Crocker at jcrocker@bidmc.harvard.edu, or at 617-754-4677.
Interested candidates should submit
Updated CV
Personal statement outlining this fellowship opportunity aligns with your overall career goals
2 letters of recommendation